BR0113296A - Processo para a preparação de sais de peptìdeos, seu uso e preparações farmacêuticas contendo os sais de peptìdeos - Google Patents

Processo para a preparação de sais de peptìdeos, seu uso e preparações farmacêuticas contendo os sais de peptìdeos

Info

Publication number
BR0113296A
BR0113296A BR0113296-2A BR0113296A BR0113296A BR 0113296 A BR0113296 A BR 0113296A BR 0113296 A BR0113296 A BR 0113296A BR 0113296 A BR0113296 A BR 0113296A
Authority
BR
Brazil
Prior art keywords
peptide salts
pharmaceutical preparations
preparation
preparations containing
peptide
Prior art date
Application number
BR0113296-2A
Other languages
English (en)
Inventor
Michael Damm
Waldemar Salonek
Juergen Engel
Horst Bauer
Gabriele Stach
Original Assignee
Zentaris Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27805895&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0113296(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zentaris Ag filed Critical Zentaris Ag
Publication of BR0113296A publication Critical patent/BR0113296A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

"PROCESSO PARA A PREPARAçãO DE SAIS DE PEPTìDEOS, SEU USO E PREPARAçõES FARMACêUTICAS CONTENDO OS SAIS DE PEPTìDEOS". A invenção refere-se a preparações farmacêuticas contendo sal de peptídeo, a sua preparação e ao seu uso. A invenção refere-se particularmente a preparações farmacêuticas contendo um sal de difícil solubilidade de agonistas ou antagonistas LHRH, tais como embonato de Cetrorelix, para a aplicação parenteral em mamíferos com efeito prolongado.
BR0113296-2A 2000-08-17 2001-08-09 Processo para a preparação de sais de peptìdeos, seu uso e preparações farmacêuticas contendo os sais de peptìdeos BR0113296A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10040700A DE10040700A1 (de) 2000-08-17 2000-08-17 Salze von biologisch aktiven Peptiden, ihre Herstellung und Verwendung
PCT/EP2001/009219 WO2002014347A2 (de) 2000-08-17 2001-08-09 Verfahren zur herstellung von peptidsalzen, deren verwendung und die peptidsalze enthaltende pharmazeutische zubereitungen
CA002355573A CA2355573A1 (en) 2000-08-17 2001-08-22 Method for the synthesis of peptide salts, their use and the pharmaceutical preparations, containing peptide salts

Publications (1)

Publication Number Publication Date
BR0113296A true BR0113296A (pt) 2003-07-15

Family

ID=27805895

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0113296-2A BR0113296A (pt) 2000-08-17 2001-08-09 Processo para a preparação de sais de peptìdeos, seu uso e preparações farmacêuticas contendo os sais de peptìdeos

Country Status (30)

Country Link
US (1) US6780972B2 (pt)
EP (1) EP1309607B1 (pt)
JP (1) JP2004506647A (pt)
CN (1) CN1187369C (pt)
AR (1) AR030371A1 (pt)
AT (1) ATE280779T1 (pt)
AU (2) AU1043902A (pt)
BG (1) BG107612A (pt)
BR (1) BR0113296A (pt)
CA (1) CA2355573A1 (pt)
CZ (1) CZ2003688A3 (pt)
DE (2) DE10040700A1 (pt)
DK (1) DK1309607T3 (pt)
EE (1) EE200300065A (pt)
ES (1) ES2230371T3 (pt)
HK (1) HK1058366A1 (pt)
HU (1) HUP0300738A3 (pt)
IL (1) IL154150A0 (pt)
MX (1) MXPA03001448A (pt)
NO (1) NO20030618L (pt)
NZ (1) NZ524023A (pt)
PL (1) PL204496B1 (pt)
PT (1) PT1309607E (pt)
RU (1) RU2266296C2 (pt)
SI (1) SI1309607T1 (pt)
SK (1) SK3032003A3 (pt)
TW (1) TWI236910B (pt)
UA (1) UA74005C2 (pt)
WO (1) WO2002014347A2 (pt)
ZA (1) ZA200300777B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
US7098305B2 (en) * 2001-09-06 2006-08-29 Ardana Bioscience Limited Sustained release of microcrystalline peptide suspensions
EP1674082A1 (de) * 2004-12-22 2006-06-28 Zentaris GmbH Verfahren zur Herstellung von sterilen Suspensionen oder Lyophilisaten schwerlöslicher basischer Peptidkomplexe, diese enthaltende pharmazeutische Formulierungen sowie ihre Verwendung als Arzneimittel
RU2525661C2 (ru) * 2012-11-15 2014-08-20 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова" Российской академии медицинских наук (ФГБУ "НИИВС им. И.И. Мечникова" РАМН) Способ получения высокотитражной антимикробной сыворотки для оценки антигенной активности противостафилококковых вакцин
CN107056894B (zh) * 2017-05-26 2021-07-20 济南康和医药科技有限公司 一种片段法固相合成醋酸加尼瑞克的方法
EP3590526A1 (en) * 2018-07-05 2020-01-08 Antev Limited A lyophilization process and a teverelix-tfa lyophilizate obtained thereby
CN114249800A (zh) * 2020-09-22 2022-03-29 深圳市星银医药有限公司 一种双羟萘酸多肽药物的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431635A (en) * 1979-06-13 1984-02-14 Coy David Howard LH-RH Antagonists
EP0041286B1 (en) * 1980-06-02 1984-08-15 Andrew Victor Schally Lh-rh antagonists
US4800191A (en) * 1987-07-17 1989-01-24 Schally Andrew Victor LHRH antagonists
DE4305225A1 (de) * 1993-02-19 1994-08-25 Asta Medica Ag Neues Herstellverfahren für Cetrorelix Lyophilisat
JP2944419B2 (ja) * 1993-05-10 1999-09-06 ノバルティス アクチエンゲゼルシャフト 持続性遊離組成物中の薬理学的活性成分の安定
CA2178592C (en) * 1993-12-09 2009-07-28 Jurgen Engel Long-acting injection suspensions and a process for their preparation
DE4342092B4 (de) * 1993-12-09 2007-01-11 Zentaris Gmbh Langwirkende Injektionssuspension und Verfahren zur Herstellung
US6054432A (en) * 1996-09-12 2000-04-25 Asta Medica Aktiengesellschaft Means for treating prostate hypertrophy and prostate cancer
EP1048301A4 (en) * 1998-01-16 2005-03-09 Takeda Chemical Industries Ltd COMPOSITIONS WITH DELAYED ACTIVE INGREDIENTS, PROCESS FOR THEIR PREPARATION AND THEIR USE

Also Published As

Publication number Publication date
SI1309607T1 (en) 2005-02-28
UA74005C2 (en) 2005-10-17
ES2230371T3 (es) 2005-05-01
DK1309607T3 (da) 2005-01-17
CA2355573A1 (en) 2003-02-22
CN1187369C (zh) 2005-02-02
ZA200300777B (en) 2003-09-18
EP1309607A2 (de) 2003-05-14
WO2002014347A2 (de) 2002-02-21
DE50104316D1 (de) 2004-12-02
HUP0300738A3 (en) 2004-08-30
CZ2003688A3 (cs) 2004-03-17
NZ524023A (en) 2004-11-26
AR030371A1 (es) 2003-08-20
ATE280779T1 (de) 2004-11-15
CN1447817A (zh) 2003-10-08
PL359495A1 (en) 2004-08-23
PL204496B1 (pl) 2010-01-29
AU1043902A (en) 2002-02-25
PT1309607E (pt) 2005-02-28
WO2002014347A3 (de) 2002-08-08
BG107612A (bg) 2003-12-31
JP2004506647A (ja) 2004-03-04
TWI236910B (en) 2005-08-01
HUP0300738A2 (hu) 2003-09-29
RU2003107560A (ru) 2005-01-27
SK3032003A3 (en) 2004-05-04
US6780972B2 (en) 2004-08-24
IL154150A0 (en) 2003-07-31
RU2266296C2 (ru) 2005-12-20
EP1309607B1 (de) 2004-10-27
MXPA03001448A (es) 2004-12-13
NO20030618D0 (no) 2003-02-07
DE10040700A1 (de) 2002-02-28
HK1058366A1 (en) 2004-05-14
US20020198146A1 (en) 2002-12-26
AU2002210439B2 (en) 2005-10-20
NO20030618L (no) 2003-02-07
EE200300065A (et) 2004-12-15

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: BLITZ F02-570 GMBH (DE)

Free format text: TRANSFERIDO POR FUSAO DE: ZENTARIS AG

B25D Requested change of name of applicant approved

Owner name: ZENTARIS GMBH (DE)

Free format text: ALTERADO DE: BLITZ F02-570 GMBH

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25G Requested change of headquarter approved

Owner name: ZENTARIS GMBH (DE)

Free format text: SEDE ALTERADA CONFORME PETICAO NO 020060058923-RJ DE 27.04.2006.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2156 DE 02/05/2012.