DE60102899D1 - Verfahren zur lösung von glucagon-ähnlichen peptid-1 (glp-1) verbindungen - Google Patents

Verfahren zur lösung von glucagon-ähnlichen peptid-1 (glp-1) verbindungen

Info

Publication number
DE60102899D1
DE60102899D1 DE60102899T DE60102899T DE60102899D1 DE 60102899 D1 DE60102899 D1 DE 60102899D1 DE 60102899 T DE60102899 T DE 60102899T DE 60102899 T DE60102899 T DE 60102899T DE 60102899 D1 DE60102899 D1 DE 60102899D1
Authority
DE
Germany
Prior art keywords
glp
solution
compound
compounds
peptid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60102899T
Other languages
English (en)
Other versions
DE60102899T2 (de
Inventor
Francis Prouty
Joseph Vincent Junior Rinella
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE60102899D1 publication Critical patent/DE60102899D1/de
Application granted granted Critical
Publication of DE60102899T2 publication Critical patent/DE60102899T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
DE60102899T 2000-01-27 2001-01-16 Verfahren zur lösung von glucagon-ähnlichen peptid-1 (glp-1) verbindungen Expired - Lifetime DE60102899T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US17843800P 2000-01-27 2000-01-27
US178438P 2000-01-27
US22405800P 2000-08-09 2000-08-09
US224058P 2000-08-09
PCT/US2001/000010 WO2001055213A2 (en) 2000-01-27 2001-01-16 Process for solubilizing glucagon-like peptide 1 (glp-1) compounds

Publications (2)

Publication Number Publication Date
DE60102899D1 true DE60102899D1 (de) 2004-05-27
DE60102899T2 DE60102899T2 (de) 2005-03-31

Family

ID=26874307

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60102899T Expired - Lifetime DE60102899T2 (de) 2000-01-27 2001-01-16 Verfahren zur lösung von glucagon-ähnlichen peptid-1 (glp-1) verbindungen

Country Status (17)

Country Link
US (4) US7598222B2 (de)
EP (1) EP1257577B1 (de)
JP (1) JP2003523366A (de)
KR (1) KR20020073184A (de)
AT (1) ATE264870T1 (de)
AU (1) AU2001232735A1 (de)
BR (1) BR0107837A (de)
CA (1) CA2396920A1 (de)
DE (1) DE60102899T2 (de)
DK (1) DK1257577T3 (de)
ES (1) ES2218381T3 (de)
HU (1) HUP0204281A3 (de)
IL (2) IL150913A0 (de)
MX (1) MXPA02007231A (de)
PT (1) PT1257577E (de)
TR (1) TR200401142T4 (de)
WO (1) WO2001055213A2 (de)

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PT1931350E (pt) * 2005-09-14 2014-02-12 Takeda Pharmaceutical Administração de inibidores de dipeptidil peptidase
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KR20120060245A (ko) 2005-09-14 2012-06-11 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
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JP2009531456A (ja) * 2006-03-28 2009-09-03 武田薬品工業株式会社 （ｒ）−３−アミノピペリジン二塩酸塩の調製
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US8093236B2 (en) 2007-03-13 2012-01-10 Takeda Pharmaceuticals Company Limited Weekly administration of dipeptidyl peptidase inhibitors
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
EP3281663B8 (de) 2008-06-13 2022-09-21 MannKind Corporation Atemluftbetriebener trockenpulverinhalator zur verabreichung von medikamenten
US9364619B2 (en) 2008-06-20 2016-06-14 Mannkind Corporation Interactive apparatus and method for real-time profiling of inhalation efforts
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
AU2010203573A1 (en) 2009-01-08 2011-06-30 Mannkind Corporation Method for treating hyperglycemia with GLP-1
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
WO2010144789A2 (en) 2009-06-12 2010-12-16 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
US8642548B2 (en) * 2009-08-07 2014-02-04 Mannkind Corporation Val (8) GLP-1 composition and method for treating functional dyspepsia and/or irritable bowel syndrome
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CN102718858B (zh) * 2011-03-29 2014-07-02 天津药物研究院 胰高血糖素样肽-1类似物单体、二聚体及其制备方法与应用
CN105667994B (zh) 2011-04-01 2018-04-06 曼金德公司 用于药物药盒的泡罩包装
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DK2872205T3 (en) 2012-07-12 2017-02-27 Mannkind Corp DRY POWDER FORMAL ADMINISTRATION SYSTEM
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
KR102499439B1 (ko) 2013-03-15 2023-02-13 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
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HUE034308T2 (en) 2013-03-21 2018-02-28 Sanofi Aventis Deutschland Preparation of hydantoin-containing peptide products
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WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
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Also Published As

Publication number Publication date
US8268780B2 (en) 2012-09-18
IL189371A0 (en) 2008-06-05
EP1257577B1 (de) 2004-04-21
KR20020073184A (ko) 2002-09-19
HUP0204281A3 (en) 2007-03-28
MXPA02007231A (es) 2002-12-09
US8222205B2 (en) 2012-07-17
US7598222B2 (en) 2009-10-06
IL150913A0 (en) 2003-02-12
DE60102899T2 (de) 2005-03-31
WO2001055213A3 (en) 2002-02-28
ES2218381T3 (es) 2004-11-16
US20130072658A1 (en) 2013-03-21
US20120101034A9 (en) 2012-04-26
CA2396920A1 (en) 2001-08-02
PT1257577E (pt) 2004-08-31
US20030060412A1 (en) 2003-03-27
AU2001232735A1 (en) 2001-08-07
TR200401142T4 (tr) 2004-07-21
HUP0204281A2 (hu) 2003-04-28
US8455433B2 (en) 2013-06-04
JP2003523366A (ja) 2003-08-05
US20120208980A1 (en) 2012-08-16
BR0107837A (pt) 2003-01-14
US20110053838A1 (en) 2011-03-03
DK1257577T3 (da) 2004-08-02
ATE264870T1 (de) 2004-05-15
EP1257577A2 (de) 2002-11-20
WO2001055213A2 (en) 2001-08-02

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Legal Events

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8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN