PT1140189E - Combinacoes de inibidores do transporte do acido biliar ileal e de derivados do acido fibrico para indicacoes cardiovasculares - Google Patents
Combinacoes de inibidores do transporte do acido biliar ileal e de derivados do acido fibrico para indicacoes cardiovascularesInfo
- Publication number
- PT1140189E PT1140189E PT99965903T PT99965903T PT1140189E PT 1140189 E PT1140189 E PT 1140189E PT 99965903 T PT99965903 T PT 99965903T PT 99965903 T PT99965903 T PT 99965903T PT 1140189 E PT1140189 E PT 1140189E
- Authority
- PT
- Portugal
- Prior art keywords
- ileal
- inhibitors
- transport
- combinations
- acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11395598P | 1998-12-23 | 1998-12-23 | |
US14260399P | 1999-07-07 | 1999-07-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1140189E true PT1140189E (pt) | 2003-09-30 |
Family
ID=26811676
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99965903T PT1140189E (pt) | 1998-12-23 | 1999-12-17 | Combinacoes de inibidores do transporte do acido biliar ileal e de derivados do acido fibrico para indicacoes cardiovasculares |
Country Status (24)
Country | Link |
---|---|
US (2) | US6638969B1 (pt) |
EP (2) | EP1140189B1 (pt) |
JP (1) | JP2002533413A (pt) |
KR (1) | KR20010102964A (pt) |
CN (1) | CN1342090A (pt) |
AR (1) | AR022023A1 (pt) |
AT (1) | ATE240120T1 (pt) |
AU (1) | AU776658B2 (pt) |
BR (1) | BR9916565A (pt) |
CA (1) | CA2356607A1 (pt) |
CZ (1) | CZ20012342A3 (pt) |
DE (1) | DE69907960T2 (pt) |
DK (1) | DK1140189T3 (pt) |
EA (1) | EA200100707A1 (pt) |
ES (1) | ES2200588T3 (pt) |
HK (2) | HK1040926B (pt) |
HU (1) | HUP0104793A2 (pt) |
IL (1) | IL143947A0 (pt) |
MX (1) | MXPA01006472A (pt) |
NO (1) | NO20013162L (pt) |
NZ (1) | NZ512537A (pt) |
PL (1) | PL348580A1 (pt) |
PT (1) | PT1140189E (pt) |
WO (1) | WO2000038727A1 (pt) |
Families Citing this family (74)
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GB0121337D0 (en) | 2001-09-04 | 2001-10-24 | Astrazeneca Ab | Chemical compounds |
GB0121621D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
GB0121622D0 (en) | 2001-09-07 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
TWI331143B (en) | 2001-09-08 | 2010-10-01 | Astrazeneca Uk Ltd | Benzothiadiazepine derivatives, process for preparing them, and pharmaceutical composition comprising them |
GB0209467D0 (en) | 2002-04-25 | 2002-06-05 | Astrazeneca Ab | Chemical compounds |
GB0213669D0 (en) | 2002-06-14 | 2002-07-24 | Astrazeneca Ab | Chemical compounds |
GB0304194D0 (en) | 2003-02-25 | 2003-03-26 | Astrazeneca Ab | Chemical compounds |
GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
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US8907095B2 (en) | 2007-10-22 | 2014-12-09 | Merck Sharp & Dohme Corp. | Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 |
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AU2009270971A1 (en) | 2008-07-16 | 2010-01-21 | Schering Corporation | Bicyclic Heterocycle Derivatives and use thereof as GPR119 modulators |
EP2379547A1 (en) | 2008-12-16 | 2011-10-26 | Schering Corporation | Pyridopyrimidine derivatives and methods of use thereof |
EP2379562A1 (en) | 2008-12-16 | 2011-10-26 | Schering Corporation | Bicyclic pyranone derivatives as nicotinic acid receptor agonists |
WO2010075273A1 (en) | 2008-12-23 | 2010-07-01 | Schering Corporation | Bicyclic heterocycle derivatives and methods of use thereof |
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US8722882B2 (en) | 2008-12-23 | 2014-05-13 | Merck Sharp & Dohme Corp. | Pyrimidine derivatives as GPCR modulators for use in the treatment of obesity and diabetes |
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US10786529B2 (en) | 2016-02-09 | 2020-09-29 | Albireo Ab | Oral cholestyramine formulation and use thereof |
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US10441604B2 (en) | 2016-02-09 | 2019-10-15 | Albireo Ab | Cholestyramine pellets and methods for preparation thereof |
ES2874546T3 (es) | 2016-02-09 | 2021-11-05 | Albireo Ab | Formulación oral de colestiramina y uso de la misma |
JP6954926B2 (ja) | 2016-02-09 | 2021-10-27 | アルビレオ・アクチボラグ | 経口コレスチラミン製剤及びその使用 |
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US10793534B2 (en) | 2018-06-05 | 2020-10-06 | Albireo Ab | Benzothia(di)azepine compounds and their use as bile acid modulators |
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US11801226B2 (en) | 2018-06-20 | 2023-10-31 | Albireo Ab | Pharmaceutical formulation of odevixibat |
CA3100691A1 (en) | 2018-06-20 | 2019-12-26 | Albireo Ab | Crystal modifications of odevixibat |
US10722457B2 (en) | 2018-08-09 | 2020-07-28 | Albireo Ab | Oral cholestyramine formulation and use thereof |
US11007142B2 (en) | 2018-08-09 | 2021-05-18 | Albireo Ab | Oral cholestyramine formulation and use thereof |
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FI3921028T3 (fi) | 2019-02-06 | 2023-01-31 | Bentsotiadiatsepiinin yhdisteet ja niiden käyttö sappihapon modulaattoreina | |
US10941127B2 (en) | 2019-02-06 | 2021-03-09 | Albireo Ab | Benzothiadiazepine compounds and their use as bile acid modulators |
US10975045B2 (en) | 2019-02-06 | 2021-04-13 | Aibireo AB | Benzothiazepine compounds and their use as bile acid modulators |
CN113453753B (zh) | 2019-02-06 | 2024-07-23 | 阿尔比里奥公司 | 苯并硫氮杂环庚三烯化合物及其用作胆汁酸调节剂的用途 |
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JP2023504644A (ja) | 2019-12-04 | 2023-02-06 | アルビレオ・アクチボラグ | ベンゾチアジアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 |
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HUE065571T2 (hu) | 2019-12-04 | 2024-06-28 | Albireo Ab | Benzotia(di)azepin vegyületek és alkalmazásuk epesav modulátorként |
EP4069359B1 (en) | 2019-12-04 | 2024-01-03 | Albireo AB | Benzothia(di)azepine compounds and their use as bile acid modulators |
ES2973355T3 (es) | 2019-12-04 | 2024-06-19 | Albireo Ab | Compuestos de benzotia(di)azepina y su uso como moduladores del ácido biliar |
US11014898B1 (en) | 2020-12-04 | 2021-05-25 | Albireo Ab | Benzothiazepine compounds and their use as bile acid modulators |
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-
1999
- 1999-12-17 DE DE69907960T patent/DE69907960T2/de not_active Expired - Fee Related
- 1999-12-17 CN CN99816270A patent/CN1342090A/zh active Pending
- 1999-12-17 JP JP2000590678A patent/JP2002533413A/ja active Pending
- 1999-12-17 US US09/465,642 patent/US6638969B1/en not_active Expired - Fee Related
- 1999-12-17 MX MXPA01006472A patent/MXPA01006472A/es unknown
- 1999-12-17 BR BR9916565-1A patent/BR9916565A/pt not_active IP Right Cessation
- 1999-12-17 WO PCT/US1999/027948 patent/WO2000038727A1/en not_active Application Discontinuation
- 1999-12-17 CZ CZ20012342A patent/CZ20012342A3/cs unknown
- 1999-12-17 ES ES99965903T patent/ES2200588T3/es not_active Expired - Lifetime
- 1999-12-17 CA CA002356607A patent/CA2356607A1/en not_active Abandoned
- 1999-12-17 EP EP99965903A patent/EP1140189B1/en not_active Revoked
- 1999-12-17 NZ NZ512537A patent/NZ512537A/en unknown
- 1999-12-17 KR KR1020017008084A patent/KR20010102964A/ko not_active Application Discontinuation
- 1999-12-17 AT AT99965903T patent/ATE240120T1/de not_active IP Right Cessation
- 1999-12-17 AU AU21579/00A patent/AU776658B2/en not_active Ceased
- 1999-12-17 PT PT99965903T patent/PT1140189E/pt unknown
- 1999-12-17 PL PL99348580A patent/PL348580A1/xx not_active Application Discontinuation
- 1999-12-17 EP EP03009706A patent/EP1336413A1/en not_active Withdrawn
- 1999-12-17 IL IL14394799A patent/IL143947A0/xx unknown
- 1999-12-17 EA EA200100707A patent/EA200100707A1/ru unknown
- 1999-12-17 DK DK99965903T patent/DK1140189T3/da active
- 1999-12-17 HU HU0104793A patent/HUP0104793A2/hu unknown
- 1999-12-23 AR ARP990106754A patent/AR022023A1/es not_active Application Discontinuation
-
2001
- 2001-06-22 NO NO20013162A patent/NO20013162L/no not_active Application Discontinuation
-
2002
- 2002-04-10 HK HK02102722.9A patent/HK1040926B/zh not_active IP Right Cessation
- 2002-09-11 HK HK02106673.9A patent/HK1045114A1/zh unknown
-
2003
- 2003-09-02 US US10/652,306 patent/US20040048846A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1140189A1 (en) | 2001-10-10 |
DE69907960D1 (de) | 2003-06-18 |
EA200100707A1 (ru) | 2001-12-24 |
CA2356607A1 (en) | 2000-07-06 |
CN1342090A (zh) | 2002-03-27 |
AU776658B2 (en) | 2004-09-16 |
BR9916565A (pt) | 2002-01-29 |
DK1140189T3 (da) | 2003-09-15 |
WO2000038727A1 (en) | 2000-07-06 |
HK1040926A1 (en) | 2002-06-28 |
KR20010102964A (ko) | 2001-11-17 |
ATE240120T1 (de) | 2003-05-15 |
IL143947A0 (en) | 2002-04-21 |
HK1045114A1 (zh) | 2002-11-15 |
EP1140189B1 (en) | 2003-05-14 |
HUP0104793A2 (en) | 2002-06-29 |
AU2157900A (en) | 2000-07-31 |
MXPA01006472A (es) | 2004-03-10 |
NO20013162L (no) | 2001-08-21 |
NZ512537A (en) | 2003-11-28 |
NO20013162D0 (no) | 2001-06-22 |
US20040048846A1 (en) | 2004-03-11 |
CZ20012342A3 (cs) | 2001-12-12 |
EP1336413A1 (en) | 2003-08-20 |
AR022023A1 (es) | 2002-09-04 |
US6638969B1 (en) | 2003-10-28 |
DE69907960T2 (de) | 2004-02-26 |
PL348580A1 (en) | 2002-06-03 |
HK1040926B (zh) | 2003-10-17 |
ES2200588T3 (es) | 2004-03-01 |
JP2002533413A (ja) | 2002-10-08 |
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