PT1044009E - Processos e composições que utilizam produtos da fermentação de arroz vermelho - Google Patents
Processos e composições que utilizam produtos da fermentação de arroz vermelho Download PDFInfo
- Publication number
- PT1044009E PT1044009E PT98954688T PT98954688T PT1044009E PT 1044009 E PT1044009 E PT 1044009E PT 98954688 T PT98954688 T PT 98954688T PT 98954688 T PT98954688 T PT 98954688T PT 1044009 E PT1044009 E PT 1044009E
- Authority
- PT
- Portugal
- Prior art keywords
- methods
- fermentation products
- red rice
- compositions
- rice fermentation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Polymers & Plastics (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Neurosurgery (AREA)
- Virology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/965,202 US6046022A (en) | 1996-09-30 | 1997-11-06 | Methods and compositions employing red rice fermentation products |
PCT/IB1998/001918 WO1999023996A2 (en) | 1997-11-06 | 1998-11-06 | Compositions containing red rice fermentation products, frementation processes and monascus strains therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1044009E true PT1044009E (pt) | 2008-03-20 |
Family
ID=25509625
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT98954688T PT1044009E (pt) | 1997-11-06 | 1998-11-06 | Processos e composições que utilizam produtos da fermentação de arroz vermelho |
Country Status (13)
Country | Link |
---|---|
US (3) | US6046022A (pt) |
EP (1) | EP1044009B8 (pt) |
JP (1) | JP2003521217A (pt) |
KR (1) | KR100683233B1 (pt) |
AT (1) | ATE383164T1 (pt) |
AU (1) | AU1170999A (pt) |
BR (1) | BR9815272A (pt) |
CA (1) | CA2309100C (pt) |
DE (1) | DE69838988T2 (pt) |
DK (1) | DK1044009T3 (pt) |
ES (1) | ES2299217T3 (pt) |
PT (1) | PT1044009E (pt) |
WO (1) | WO1999023996A2 (pt) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2758037B2 (ja) * | 1989-08-04 | 1998-05-25 | 株式会社アマダ | タレットパンチプレスの金型インデックス装置 |
US7238348B2 (en) * | 1996-09-30 | 2007-07-03 | Beijing Peking University Wbl Corporation Ltd. | Method of treatment of osteoporosis with compositions of red rice fermentation products |
US6376476B1 (en) * | 1996-12-13 | 2002-04-23 | Zymogenetics Corporation | Isoprenoid pathway inhibitors for stimulating bone growth |
US6410521B1 (en) | 1998-06-12 | 2002-06-25 | Osteoscreen, Inc. | Nutritional supplements for stimulating bone growth |
US6372462B2 (en) * | 1999-10-15 | 2002-04-16 | Medmyco Ltd. | Process for producing, methods and compositions of cholesterol lowering agents from higher basidiomycetes mushrooms |
DE19951474A1 (de) * | 1999-10-26 | 2001-05-23 | Homoeopathie Union Dhu Arzneim | Celluloseether stabilisierte Öl-in-Wasser Emulsionen als Träger für homöopatische und pflanzliche Wirkstoffe |
KR20010038797A (ko) * | 1999-10-27 | 2001-05-15 | 김길환 | 홍국을 이용한 일산화질소 생성제 조성물 및 이를 이용한 약품 조성물 |
JP4585070B2 (ja) * | 1999-12-08 | 2010-11-24 | 丸善製薬株式会社 | サイクリックampホスホジエステラーゼ阻害剤および抗アレルギー・抗炎症剤 |
WO2001043711A1 (en) * | 1999-12-14 | 2001-06-21 | Unilever Plc | Cosmetic skin conditioning compositions containing red yeast rice extract |
AUPQ711700A0 (en) * | 2000-04-26 | 2000-05-18 | Macquarie Research Limited | Fluorescent compounds |
US6436406B1 (en) * | 2000-06-15 | 2002-08-20 | A. Glenn Braswell | Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides and atherosclerosis |
EP1176208A1 (en) * | 2000-07-28 | 2002-01-30 | Société des Produits Nestlé S.A. | Koji molds and use thereof for preparing cholesterol-lowering products |
EP1190629A1 (de) * | 2000-09-18 | 2002-03-27 | EnergyBalance AG | Omega-3 Fettsäuren mit Vitamin E-Nahrungskonzentrat |
KR100404067B1 (ko) * | 2001-01-04 | 2003-11-01 | 주식회사 이지바이오시스템 | 유기태 셀레늄 함유 홍보리쌀 및 그의 제조방법 |
JP3711377B2 (ja) * | 2001-01-31 | 2005-11-02 | 共栄化学工業株式会社 | 乳化剤及び乳化化粧料並びにその製造法 |
EP1358343A2 (en) * | 2001-02-09 | 2003-11-05 | Unilever N.V. | Process for the preparation of one or more statins by fermentation |
US20020197274A1 (en) * | 2001-04-19 | 2002-12-26 | Ming-Shi Shiao | Lithospermic acid-containing composition |
FR2834718B1 (fr) * | 2002-01-15 | 2004-12-24 | Cognis France Sa | Substances actives cosmetiques et/ou pharmaceutiques |
KR100554963B1 (ko) * | 2002-01-18 | 2006-02-24 | 지니스생명공학 주식회사 | 가축사료 첨가제용 홍국균 배양배지 및 그 방법과 생산제품 |
IL147942A0 (en) * | 2002-01-31 | 2002-08-14 | Enzymotec Ltd | Method of fractionation of phytosterol esters in oil and products obtained thereby |
KR100455905B1 (ko) * | 2002-02-20 | 2004-11-06 | 주식회사한국신약 | 색소생산능이 높은 모나스커스 퍼퍼러스 klhs4 |
KR100379075B1 (en) * | 2002-03-07 | 2003-04-08 | Jinis Biopharmaceuticals Co | Method for producing low cholesterol animal food product and food product therefrom |
US6953574B2 (en) * | 2002-06-21 | 2005-10-11 | Technology Commercialization, Inc. | Method for producing a fermented hydrolyzed medium containing microorganisms |
US20040081663A1 (en) * | 2002-10-25 | 2004-04-29 | Chun-Min Chang | Pharmaceutical composition for treatment and prevention of cancer and the preparation thereof |
IL155136A0 (en) * | 2003-02-10 | 2003-10-31 | Enzymotec Ltd | A composition for reducing blood cholesterol and triglycerides |
US20060233863A1 (en) * | 2003-02-10 | 2006-10-19 | Enzymotec Ltd. | Oils enriched with diacylglycerols and phytosterol esters and unit dosage forms thereof for use in therapy |
US7157107B2 (en) * | 2004-01-14 | 2007-01-02 | Tzu-Ming Pan | Method for producing eggs with low cholesterol level |
RU2006141847A (ru) * | 2004-04-28 | 2008-06-10 | Юнилевер Н.В. (Nl) | Композиция, содержащая статины |
KR101268206B1 (ko) * | 2004-08-09 | 2013-05-27 | 엔지모테크 리미티드 | 당뇨병용 식품 |
RU2394576C2 (ru) * | 2004-08-10 | 2010-07-20 | Энзимотек Лтд. | Способы лечения, требующие фитокомпонентов |
US20060153900A1 (en) * | 2005-01-13 | 2006-07-13 | Pins Joel J | Dietary supplement for treatment of lipid risk factors |
US20060292679A1 (en) * | 2005-06-27 | 2006-12-28 | Jerome Pellaud | Beer containing monascus-derived pigments |
US20080102081A1 (en) * | 2006-08-08 | 2008-05-01 | ALEXIS Brian | Preparations and applications for treatment of high cholesterol levels |
US20080166420A1 (en) * | 2007-01-04 | 2008-07-10 | Sones Scott F | Krill Oil Compositions |
US20100119600A1 (en) | 2007-06-01 | 2010-05-13 | Joar Opheim | Substances for reducing occurrence of major cardiac events comprising red yeast rice extract and omega-3 polyunsaturated fatty acid or derivative thereof |
US20120171311A1 (en) * | 2007-06-01 | 2012-07-05 | Opheim Joar A | Substances for reducing occurrence of major cardiac events comprising epa or derivatives thereof, optionally, dha or derivatives thereof and monacolin k |
US20080299187A1 (en) * | 2007-06-01 | 2008-12-04 | Joar Opheim | Substances for Reducing Occurence of Major Cardiac Events in Humans |
FR2936711B1 (fr) * | 2008-10-06 | 2012-09-21 | Holymark | Composition orale, en particulier complement alimentaire comprenant un extrait sec de feuilles d'artichaut et de la levure de riz rouge |
KR101079800B1 (ko) | 2009-04-16 | 2011-11-04 | 연세대학교 산학협력단 | 지방전구세포의 분화를 저해하는 모나스커스 색소 아민 유도체 |
TW201038205A (en) * | 2009-04-29 | 2010-11-01 | Sunway Biotech Co Ltd | The compositions of Monascus fermented products with a function that reduces body fatness formation and the method for manufacturing the same |
KR101048032B1 (ko) * | 2009-10-15 | 2011-07-13 | 성신여자대학교 산학협력단 | 천연 Statin과 CoQ10 화합물이 강화된 약제학적 조성물 |
FR2951908B1 (fr) * | 2009-11-03 | 2012-03-30 | Valorimer | Composition comprenant une poudre de nopal et de la levure de riz rouge et complement alimentaire comprenant cette composition |
FR2957754B1 (fr) * | 2010-03-26 | 2012-04-27 | Inst Nat De La Rech Agronomique Inra | Utilisation d'un produit de fermentation fongique comme complement alimentaire |
KR20120021725A (ko) * | 2010-08-13 | 2012-03-09 | 양영국 | 홍국을 이용한 기능성 곡류의 제조방법 |
WO2012063985A2 (ko) * | 2010-11-12 | 2012-05-18 | 김용문 | 콜레스테롤 저하용 햄버거 및 이의 제조방법 |
TWI473612B (zh) * | 2010-12-23 | 2015-02-21 | Food Industry Res & Dev Inst | 新穎紫紅麴酮、其製備方法及紫紅麴酮之應用 |
CN102526333B (zh) * | 2011-01-04 | 2014-04-09 | 统欣生物科技股份有限公司 | 调整血脂及保护心血管的组合物 |
CN102617533B (zh) * | 2011-02-01 | 2014-08-27 | 北京北大维信生物科技有限公司 | 一种从红曲中分离的化合物、其制备方法及用途 |
CN102621238A (zh) * | 2011-02-01 | 2012-08-01 | 北京北大维信生物科技有限公司 | 一种测定HMG-CoA还原酶抑制剂浓度的方法 |
GB201115417D0 (en) * | 2011-09-06 | 2011-10-19 | Ip Science Ltd | Products and methods |
TWI518094B (zh) * | 2011-12-26 | 2016-01-21 | Univ Beijing Peking Wbl Biotech Co Ltd | One kind of derivatives of sterols, their preparation and use |
WO2013138409A1 (en) * | 2012-03-14 | 2013-09-19 | Nordic Naturals, Inc. | Red yeast rice extract high in monacolin k content |
CN102757874B (zh) * | 2012-06-28 | 2015-02-18 | 吉山红(福建)酒业有限公司 | 一种富含洛伐他汀的红曲黄酒及其酿造方法 |
RO128803A0 (ro) | 2012-10-12 | 2013-09-30 | Ion Gigel Fulga | Compoziţie pentru tratamentul sau prevenirea dislipidemiilor |
US9168277B2 (en) | 2013-03-14 | 2015-10-27 | Auburn University | Nutraceutical compositions produced from co-products of corn or milo ethanol fermentation and methods of making and using thereof |
ITUB20150541A1 (it) | 2015-03-03 | 2016-09-03 | Acraf | Composizione comprendente sostanze e/o estratti naturali |
CN105124597A (zh) * | 2015-08-04 | 2015-12-09 | 江苏大学 | 一种红曲玉米皮功能性食品的制备方法及其应用 |
ITUA20162441A1 (it) * | 2016-04-08 | 2017-10-08 | Massimo Farinon | Pasta alimentare |
CN110013016A (zh) * | 2018-03-29 | 2019-07-16 | 晨钟荣福国际中医药实业有限公司 | 一种藕瘦身营养粉及其制备方法和用途 |
EP3590356A1 (en) | 2018-07-05 | 2020-01-08 | Uriach Consumer Healthcare, S.L. | Composition for controlling and reducing blood cholesterol levels |
CN111729065A (zh) * | 2020-08-05 | 2020-10-02 | 温州海鹤药业有限公司 | 一种三余神曲的生产工艺 |
CN112245512A (zh) * | 2020-11-11 | 2021-01-22 | 烟台大学 | 一种用于治疗慢性良性的胃病及食管病的中药组合物的制备方法 |
EP4000626A1 (en) | 2020-11-16 | 2022-05-25 | concrete flowers GmbH | Pharmaceutical preparation |
CN112602880B (zh) * | 2020-12-14 | 2022-06-24 | 安徽农业大学 | 一种提高曲种发酵生产红曲米色价的方法 |
CN116083252B (zh) * | 2023-04-12 | 2023-06-27 | 北京一品堂医药科技有限公司 | 一种高产降脂天然莫拉可林k的红曲米发酵制备方法 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5612114B2 (pt) | 1974-06-07 | 1981-03-18 | ||
US4049495A (en) | 1974-06-07 | 1977-09-20 | Sankyo Company Limited | Physiologically active substances and fermentative process for producing the same |
US4031250A (en) * | 1974-11-20 | 1977-06-21 | General Foods Corporation | Method for imparting red color to animal food |
DE2748825C2 (de) | 1976-11-02 | 1986-11-27 | Sankyo Co., Ltd., Tokio/Tokyo | Substituierte 3,5-Dihydroxyheptansäurederivate und diese enthaltende Arzneimittel gegen Hyperlipämie |
JPS5925599B2 (ja) | 1979-02-20 | 1984-06-19 | 三共株式会社 | 新生理活性物質モナコリンkおよびその製造法 |
JPS55150898A (en) * | 1979-05-11 | 1980-11-25 | Sankyo Co Ltd | Preparation of a new physiologically active substance mb-530b |
US4319039A (en) | 1979-06-15 | 1982-03-09 | Merck & Co., Inc. | Preparation of ammonium salt of hypocholesteremic fermentation product |
US4231938A (en) | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
US4294926A (en) | 1979-06-15 | 1981-10-13 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
ES493726A0 (es) | 1979-07-27 | 1981-06-16 | Sankyo Co | Un procedimiento para la preparacion de sales y esteres, de monacolina k utiles como agentes antitlipercolesteremicos. |
US4294846A (en) | 1979-09-21 | 1981-10-13 | Merck & Co., Inc. | Hypocholesteremic fermentation products and products of preparation |
US4342767A (en) | 1980-01-23 | 1982-08-03 | Merck & Co., Inc. | Hypocholesteremic fermentation products |
US4420491A (en) | 1980-05-28 | 1983-12-13 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
JPS5843783A (ja) * | 1981-09-08 | 1983-03-14 | Akira Endo | 麹 |
JPS62132878A (ja) * | 1985-12-04 | 1987-06-16 | Nippon Kayaku Co Ltd | 新生理活性物質モナコリンm及びその製造法 |
JPS63198973A (ja) * | 1987-02-14 | 1988-08-17 | Gunze Ltd | 紅麹の製造方法 |
CA2062023A1 (en) * | 1992-02-10 | 1993-08-11 | Jagroop S. Dahiya | Novel fungal strains and use thereof in antibiotic production |
CN1075875A (zh) * | 1993-01-01 | 1993-09-08 | 北京大学 | 降脂红曲及制备方法 |
SI9300303A (en) * | 1993-06-08 | 1994-12-31 | Krka Tovarna Zdravil | Process for isolation of hypolipemic effective substance |
BG61613B1 (bg) * | 1994-06-24 | 1998-01-30 | Анна Куюмджиева | Щам моnаsсus рurрurеus-продуцент на пигмент и биоактивни продукти |
CN1106230A (zh) * | 1994-10-19 | 1995-08-09 | 袁保善 | 红绿长生素及其专门生产工艺 |
CN1110560A (zh) * | 1995-01-24 | 1995-10-25 | 成都世新药物技术开发中心 | 脂必妥药剂 |
CN1155421A (zh) * | 1996-09-26 | 1997-07-30 | 张茂良 | 一种治疗高血脂症及相关心脑血管疾病的红曲制剂 |
CN1173361A (zh) * | 1997-07-22 | 1998-02-18 | 朱建中 | 降压降脂降血糖红曲药物及其制备方法 |
-
1997
- 1997-11-06 US US08/965,202 patent/US6046022A/en not_active Expired - Lifetime
-
1998
- 1998-11-06 CA CA002309100A patent/CA2309100C/en not_active Expired - Lifetime
- 1998-11-06 DK DK98954688T patent/DK1044009T3/da active
- 1998-11-06 DE DE69838988T patent/DE69838988T2/de not_active Expired - Lifetime
- 1998-11-06 ES ES98954688T patent/ES2299217T3/es not_active Expired - Lifetime
- 1998-11-06 AU AU11709/99A patent/AU1170999A/en not_active Abandoned
- 1998-11-06 WO PCT/IB1998/001918 patent/WO1999023996A2/en active IP Right Grant
- 1998-11-06 BR BR9815272-6A patent/BR9815272A/pt not_active Application Discontinuation
- 1998-11-06 KR KR1020007004921A patent/KR100683233B1/ko not_active IP Right Cessation
- 1998-11-06 AT AT98954688T patent/ATE383164T1/de active
- 1998-11-06 PT PT98954688T patent/PT1044009E/pt unknown
- 1998-11-06 JP JP2000520093A patent/JP2003521217A/ja active Pending
- 1998-11-06 EP EP98954688A patent/EP1044009B8/en not_active Expired - Lifetime
-
2000
- 2000-04-04 US US09/542,438 patent/US6632428B1/en not_active Expired - Lifetime
-
2002
- 2002-12-17 US US10/321,259 patent/US20030194413A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2003521217A (ja) | 2003-07-15 |
CA2309100C (en) | 2009-09-15 |
DK1044009T3 (da) | 2008-04-28 |
EP1044009A2 (en) | 2000-10-18 |
ATE383164T1 (de) | 2008-01-15 |
WO1999023996A2 (en) | 1999-05-20 |
AU1170999A (en) | 1999-05-31 |
US6632428B1 (en) | 2003-10-14 |
US20030194413A1 (en) | 2003-10-16 |
US6046022A (en) | 2000-04-04 |
BR9815272A (pt) | 2000-12-19 |
DE69838988D1 (de) | 2008-02-21 |
ES2299217T3 (es) | 2008-05-16 |
KR20010031848A (ko) | 2001-04-16 |
KR100683233B1 (ko) | 2007-02-20 |
CA2309100A1 (en) | 1999-05-20 |
EP1044009A4 (en) | 2001-07-18 |
WO1999023996A3 (en) | 1999-08-19 |
EP1044009B1 (en) | 2008-01-09 |
DE69838988T2 (de) | 2009-01-15 |
EP1044009B8 (en) | 2008-02-20 |
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