PT1036794E - Derivados de 2-aril-8-oxodi-hidropurina processo para a sua producao composicoes medicinais que os contem e seus intermediarios - Google Patents

Derivados de 2-aril-8-oxodi-hidropurina processo para a sua producao composicoes medicinais que os contem e seus intermediarios

Info

Publication number
PT1036794E
PT1036794E PT98955937T PT98955937T PT1036794E PT 1036794 E PT1036794 E PT 1036794E PT 98955937 T PT98955937 T PT 98955937T PT 98955937 T PT98955937 T PT 98955937T PT 1036794 E PT1036794 E PT 1036794E
Authority
PT
Portugal
Prior art keywords
hydropurin
oxodi
intermediaries
aryl
contain
Prior art date
Application number
PT98955937T
Other languages
English (en)
Inventor
Teruya Murata
Kiyoshi Furukawa
Makoto Oka
Kaoru Masumoto
Katsunori Kondo
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of PT1036794E publication Critical patent/PT1036794E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PT98955937T 1997-12-03 1998-11-26 Derivados de 2-aril-8-oxodi-hidropurina processo para a sua producao composicoes medicinais que os contem e seus intermediarios PT1036794E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP35000097 1997-12-03

Publications (1)

Publication Number Publication Date
PT1036794E true PT1036794E (pt) 2003-11-28

Family

ID=18407561

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98955937T PT1036794E (pt) 1997-12-03 1998-11-26 Derivados de 2-aril-8-oxodi-hidropurina processo para a sua producao composicoes medicinais que os contem e seus intermediarios

Country Status (27)

Country Link
US (1) US6372740B1 (pt)
EP (1) EP1036794B1 (pt)
JP (1) JP3815966B2 (pt)
KR (1) KR100494347B1 (pt)
CN (1) CN1146566C (pt)
AR (1) AR017796A1 (pt)
AT (1) ATE248169T1 (pt)
AU (1) AU744014B2 (pt)
BR (1) BR9815140A (pt)
CA (1) CA2312885C (pt)
DE (1) DE69817611T2 (pt)
DK (1) DK1036794T3 (pt)
ES (1) ES2205574T3 (pt)
HK (1) HK1028769A1 (pt)
HU (1) HUP0004422A3 (pt)
ID (1) ID24929A (pt)
IL (1) IL135920A0 (pt)
NO (1) NO20002835L (pt)
NZ (1) NZ504457A (pt)
PL (1) PL191489B1 (pt)
PT (1) PT1036794E (pt)
RU (1) RU2223272C2 (pt)
SK (1) SK285703B6 (pt)
TR (1) TR200001600T2 (pt)
TW (1) TW502034B (pt)
WO (1) WO1999028320A1 (pt)
ZA (1) ZA9810490B (pt)

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US7989459B2 (en) * 2006-02-17 2011-08-02 Pharmacopeia, Llc Purinones and 1H-imidazopyridinones as PKC-theta inhibitors
US20090281075A1 (en) * 2006-02-17 2009-11-12 Pharmacopeia, Inc. Isomeric purinones and 1h-imidazopyridinones as pkc-theta inhibitors
US7951803B2 (en) * 2006-03-09 2011-05-31 Pharmacopeia, Llc 8-heteroarylpurine MNK2 inhibitors for treating metabolic disorders
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US7902187B2 (en) * 2006-10-04 2011-03-08 Wyeth Llc 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression
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RU2478635C2 (ru) 2006-10-19 2013-04-10 СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи Гетероарильные соединения, содержащие их композиции и способы лечения с применением этих соединений
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US8110578B2 (en) 2008-10-27 2012-02-07 Signal Pharmaceuticals, Llc Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway
US8473571B2 (en) 2009-01-08 2013-06-25 Microsoft Corporation Synchronizing presentation states between multiple applications
CN102656172B (zh) * 2009-09-09 2016-03-23 大日本住友制药株式会社 8-氧代二氢嘌呤衍生物
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WO2012168697A1 (en) 2011-06-06 2012-12-13 Imperial Innovations Limited Methods to predict binding affinity of tspo imaging agents to tspo
CN107157990B (zh) 2011-10-19 2020-01-07 西格诺药品有限公司 利用tor激酶抑制剂治疗癌症
UA114496C2 (uk) 2011-12-02 2017-06-26 Сігнал Фармасьютікалз, Елелсі ФАРМАЦЕВТИЧНІ КОМПОЗИЦІЇ 7-(6-(2-ГІДРОКСИПРОПАН-2-ІЛ)ПІРИДИН-3-ІЛ)-1-((ТРАНС)-4-МЕТОКСИЦИКЛОГЕКСИЛ)-3,4-ДИГІДРОПІРАЗИНО[2,3-b]ПІРАЗИН-2(1H)-ОНУ, ЇХ ТВЕРДІ ФОРМИ І СПОСОБИ ЇХ ЗАСТОСУВАННЯ
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BR112015016997A2 (pt) 2013-01-16 2017-07-11 Signal Pharm Llc composto, composição farmacêutica e método para o tratamento ou prevenção de câncer de mama
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Also Published As

Publication number Publication date
EP1036794A1 (en) 2000-09-20
PL340925A1 (en) 2001-03-12
US6372740B1 (en) 2002-04-16
SK7972000A3 (en) 2001-03-12
AU744014B2 (en) 2002-02-14
EP1036794A4 (en) 2001-12-12
DE69817611T2 (de) 2004-02-26
CN1146566C (zh) 2004-04-21
NZ504457A (en) 2001-12-21
WO1999028320A1 (fr) 1999-06-10
TW502034B (en) 2002-09-11
ZA9810490B (en) 1999-05-20
HUP0004422A3 (en) 2001-10-29
HUP0004422A2 (hu) 2001-04-28
DE69817611D1 (de) 2003-10-02
SK285703B6 (sk) 2007-06-07
DK1036794T3 (da) 2003-12-22
CN1284076A (zh) 2001-02-14
CA2312885A1 (en) 1999-06-10
ATE248169T1 (de) 2003-09-15
TR200001600T2 (tr) 2000-11-21
AU1260499A (en) 1999-06-16
JP3815966B2 (ja) 2006-08-30
NO20002835L (no) 2000-07-24
ID24929A (id) 2000-08-31
AR017796A1 (es) 2001-10-24
CA2312885C (en) 2008-01-29
ES2205574T3 (es) 2004-05-01
HK1028769A1 (en) 2001-03-02
RU2223272C2 (ru) 2004-02-10
BR9815140A (pt) 2000-10-10
EP1036794B1 (en) 2003-08-27
KR100494347B1 (ko) 2005-06-13
PL191489B1 (pl) 2006-05-31
NO20002835D0 (no) 2000-06-02
KR20010032686A (ko) 2001-04-25
IL135920A0 (en) 2001-05-20

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