PL361356A1 - Nowe pochodne indolu i ich zastosowanie jako leków - Google Patents

Nowe pochodne indolu i ich zastosowanie jako leków

Info

Publication number
PL361356A1
PL361356A1 PL36135601A PL36135601A PL361356A1 PL 361356 A1 PL361356 A1 PL 361356A1 PL 36135601 A PL36135601 A PL 36135601A PL 36135601 A PL36135601 A PL 36135601A PL 361356 A1 PL361356 A1 PL 361356A1
Authority
PL
Poland
Prior art keywords
medicaments
indole derivatives
novel indole
novel
derivatives
Prior art date
Application number
PL36135601A
Other languages
English (en)
Other versions
PL208673B1 (pl
Inventor
Peter Emig
Gerald Bacher
Dietmar Reichert
Silke Baasner
Beate Aue
Bernd Nickel
Eckhard Günther
Original Assignee
Zentaris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Gmbh filed Critical Zentaris Gmbh
Publication of PL361356A1 publication Critical patent/PL361356A1/pl
Publication of PL208673B1 publication Critical patent/PL208673B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
PL361356A 2000-07-28 2001-07-26 Pochodne indolu, sposób wytwarzania pochodnych indolu, zastosowanie pochodnych indolu do wytwarzania leków oraz lek zawierający pochodną indolu PL208673B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10037310A DE10037310A1 (de) 2000-07-28 2000-07-28 Neue Indolderivate und deren Verwendung als Arzneimittel
PCT/EP2001/008644 WO2002010152A2 (de) 2000-07-28 2001-07-26 Neue indolderivate und deren verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
PL361356A1 true PL361356A1 (pl) 2004-10-04
PL208673B1 PL208673B1 (pl) 2011-05-31

Family

ID=7650860

Family Applications (1)

Application Number Title Priority Date Filing Date
PL361356A PL208673B1 (pl) 2000-07-28 2001-07-26 Pochodne indolu, sposób wytwarzania pochodnych indolu, zastosowanie pochodnych indolu do wytwarzania leków oraz lek zawierający pochodną indolu

Country Status (31)

Country Link
US (3) US7365081B2 (pl)
EP (3) EP1309585B1 (pl)
JP (1) JP5113973B2 (pl)
KR (1) KR100810453B1 (pl)
CN (1) CN1215066C (pl)
AR (1) AR055209A1 (pl)
AT (1) ATE392420T1 (pl)
AU (2) AU8975801A (pl)
BG (1) BG66457B1 (pl)
BR (1) BR0112807A (pl)
CA (3) CA2704693A1 (pl)
CY (1) CY1108770T1 (pl)
CZ (1) CZ304197B6 (pl)
DE (2) DE10037310A1 (pl)
DK (1) DK1309585T3 (pl)
ES (1) ES2303532T3 (pl)
HK (1) HK1058201A1 (pl)
HU (1) HU229254B1 (pl)
IL (2) IL153930A0 (pl)
MX (1) MXPA03000644A (pl)
NO (1) NO324594B1 (pl)
NZ (1) NZ524404A (pl)
PL (1) PL208673B1 (pl)
PT (1) PT1309585E (pl)
RU (1) RU2270196C9 (pl)
SI (1) SI1309585T1 (pl)
SK (1) SK288085B6 (pl)
TW (1) TWI291955B (pl)
UA (1) UA80670C2 (pl)
WO (1) WO2002010152A2 (pl)
ZA (1) ZA200300584B (pl)

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JP2005504790A (ja) 2001-09-13 2005-02-17 シンタ ファーマスーティカルズ コーポレイション 癌を治療するための３−グリオキシリルアミドインドール
EP1484329A1 (de) * 2003-06-06 2004-12-08 Zentaris GmbH Indolderivate mit Apoptose induzierender Wirkung
CA2526663C (en) * 2003-06-05 2011-07-19 Zentaris Gmbh Indole derivatives with apoptosis-inducing effect
US7205299B2 (en) * 2003-06-05 2007-04-17 Zentaris Gmbh Indole derivatives having an apoptosis-inducing effect
US7211588B2 (en) * 2003-07-25 2007-05-01 Zentaris Gmbh N-substituted indolyl-3-glyoxylamides, their use as medicaments and process for their preparation
US20050124623A1 (en) 2003-11-26 2005-06-09 Bender John A. Diazaindole-dicarbonyl-piperazinyl antiviral agents
US20060100432A1 (en) 2004-11-09 2006-05-11 Matiskella John D Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US7851476B2 (en) 2005-12-14 2010-12-14 Bristol-Myers Squibb Company Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine
US7807671B2 (en) 2006-04-25 2010-10-05 Bristol-Myers Squibb Company Diketo-piperazine and piperidine derivatives as antiviral agents
KR20090054984A (ko) 2006-08-07 2009-06-01 아이언우드 파마슈티컬스, 인코포레이티드 인돌 화합물
SG190667A1 (en) 2008-05-23 2013-06-28 Panmira Pharmaceuticals Llc 5-lipoxygenase-activating protein inhibitor
AR084433A1 (es) 2010-12-22 2013-05-15 Ironwood Pharmaceuticals Inc Inhibidores de la faah y composiciones farmaceuticas que los contienen

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FR3632M (fr) 1962-10-31 1965-10-25 Thomae Gmbh Dr K Dérivés de l'acide 6-amino-pénicillanique.
US6204261B1 (en) 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US3573294A (en) * 1968-03-14 1971-03-30 Glaxo Lab Ltd 7 - (arylglyoxamido)cephalosporanic acids and their salts and alpha-carbonyl derivatives
US5192770A (en) 1990-12-07 1993-03-09 Syntex (U.S.A.) Inc. Serotonergic alpha-oxoacetamides
US5480883A (en) * 1991-05-10 1996-01-02 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
CA2195850A1 (en) * 1994-08-03 1996-02-15 Guillaume Lebaut Substituted indoles
US5732113A (en) 1996-06-20 1998-03-24 Stanford University Timing and frequency synchronization of OFDM signals
DE19636150A1 (de) * 1996-09-06 1998-03-12 Asta Medica Ag N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung
US6514977B1 (en) 1997-05-22 2003-02-04 G.D. Searle & Company Substituted pyrazoles as p38 kinase inhibitors
AU765427B2 (en) 1998-02-25 2003-09-18 Genetics Institute, Llc Inhibitors of phospholipase enzymes
WO1999046267A1 (en) 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
DE19946301A1 (de) * 1998-04-02 2001-04-19 Asta Medica Ag Indolyl-3-glyoxylsäure-Derivate mit therapeutisch wertvollen Eigenschaften
DE19814838C2 (de) 1998-04-02 2001-01-18 Asta Medica Ag Indolyl-3-glyoxylsäure-Derivate mit Antitumorwirkung
AU5947399A (en) 1998-04-27 1999-11-16 Hoechst Marion Roussel Deutschland Gmbh A new glucose-6-phosphate translocase inhibitor L 970885 from an actinomycete SP., and chemical derivatives thereof, a process for the preparation and theirv use as pharmaceuticals
TR200003130T2 (tr) 1998-04-28 2001-01-22 Arzneimittelwerk Dresden Gmbh Yeni hidroksiindoller, bunların fosfodiesteraz 4 inhibitörleri olarak kullanımları ve hazırlanmaları için işlemler
EP1083918A1 (en) 1998-06-08 2001-03-21 Advanced Medicine, Inc. Novel therapeutic agents that modulate 5-ht receptors
EP1087960B1 (en) 1998-06-17 2011-03-23 Eisai R&D Management Co., Ltd. Macrocyclic analogs and methods of their use and preparation
GB9823871D0 (en) 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
WO2000031603A1 (de) * 1998-11-19 2000-06-02 Infineon Technologies Ag Schaltungsanordnung zum erzeugen einer stabilisierten versorgungsspannung für mehrere verbraucher
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WO2001017516A2 (en) 1999-09-10 2001-03-15 Novo Nordisk A/S Method of inhibiting protein tyrosine phosphatase 1b and/or t-cell protein tyrosine phosphatase and/or other ptpases with an asp residue at position 48
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AU2001269769A1 (en) 2000-06-07 2001-12-17 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Methods for making bis-heterocyclic alkaloids
DE10035927A1 (de) * 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
IT1318641B1 (it) * 2000-07-25 2003-08-27 Novuspharma Spa Ammidi di acidi 2-(1h-indol-3-il)-2-oxo-acetici ad attivita'antitumorale.
DE10037310A1 (de) * 2000-07-28 2002-02-07 Asta Medica Ag Neue Indolderivate und deren Verwendung als Arzneimittel
US7205299B2 (en) * 2003-06-05 2007-04-17 Zentaris Gmbh Indole derivatives having an apoptosis-inducing effect
GB0525623D0 (en) 2005-12-16 2006-01-25 Hill Nicholas P R RFID reader
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WO2008105082A1 (ja) * 2007-02-28 2008-09-04 Ibiden Co., Ltd. ハニカム構造体
WO2008105081A1 (ja) * 2007-02-28 2008-09-04 Ibiden Co., Ltd. ハニカムフィルタ
WO2008126334A1 (ja) * 2007-03-30 2008-10-23 Ibiden Co., Ltd. ハニカム構造体の製造方法
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JPWO2008126335A1 (ja) * 2007-03-30 2010-07-22 イビデン株式会社 ハニカム構造体及びハニカム構造体の製造方法
WO2008139608A1 (ja) * 2007-05-14 2008-11-20 Ibiden Co., Ltd. ハニカム構造体及び該ハニカム構造体の製造方法

Also Published As

Publication number Publication date
HU229254B1 (en) 2013-10-28
EP1939195A1 (de) 2008-07-02
HK1058201A1 (en) 2004-05-07
DE50113867D1 (de) 2008-05-29
CA2704693A1 (en) 2002-01-28
KR20030017658A (ko) 2003-03-03
US20030100597A1 (en) 2003-05-29
EP1309585A2 (de) 2003-05-14
CN1447805A (zh) 2003-10-08
HUP0300677A2 (hu) 2003-11-28
US8008324B2 (en) 2011-08-30
ATE392420T1 (de) 2008-05-15
DE10037310A1 (de) 2002-02-07
PL208673B1 (pl) 2011-05-31
ZA200300584B (en) 2003-07-18
CZ304197B6 (cs) 2013-12-27
NO20030382D0 (no) 2003-01-24
JP2004505075A (ja) 2004-02-19
US7365081B2 (en) 2008-04-29
KR100810453B1 (ko) 2008-03-07
SK288085B6 (sk) 2013-06-03
JP5113973B2 (ja) 2013-01-09
AU2001289758B2 (en) 2006-07-06
DK1309585T3 (da) 2008-06-23
WO2002010152A2 (de) 2002-02-07
RU2270196C2 (ru) 2006-02-20
SK2222003A3 (en) 2004-04-06
CY1108770T1 (el) 2014-04-09
MXPA03000644A (es) 2003-06-06
WO2002010152A3 (de) 2002-08-01
BG107560A (bg) 2003-10-31
RU2270196C9 (ru) 2007-11-27
CA2704691A1 (en) 2002-01-28
EP1309585B1 (de) 2008-04-16
UA80670C2 (en) 2007-10-25
US7989453B2 (en) 2011-08-02
CA2354210A1 (en) 2002-01-28
US20080153875A1 (en) 2008-06-26
EP2163552A1 (de) 2010-03-17
BR0112807A (pt) 2003-07-01
NO20030382L (no) 2003-02-20
NO324594B1 (no) 2007-11-26
NZ524404A (en) 2004-08-27
IL153930A (en) 2008-11-03
CA2354210C (en) 2010-09-14
PT1309585E (pt) 2008-06-09
TWI291955B (en) 2008-01-01
AU8975801A (en) 2002-02-13
BG66457B1 (bg) 2014-10-31
SI1309585T1 (sl) 2008-08-31
AR055209A1 (es) 2007-08-15
CN1215066C (zh) 2005-08-17
IL153930A0 (en) 2003-07-31
CZ2003500A3 (cs) 2004-03-17
US20080108819A1 (en) 2008-05-08
ES2303532T3 (es) 2008-08-16

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Legal Events

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RECP Rectifications of patent specification