PL353874A1 - Gen Streptomyces avermitilis decydujący o stosunkuGen Streptomyces avermitilis decydujący o stosunku awermektyn B1:B2 awermektyn B1:B2 - Google Patents

Gen Streptomyces avermitilis decydujący o stosunkuGen Streptomyces avermitilis decydujący o stosunku awermektyn B1:B2 awermektyn B1:B2

Info

Publication number
PL353874A1
PL353874A1 PL00353874A PL35387400A PL353874A1 PL 353874 A1 PL353874 A1 PL 353874A1 PL 00353874 A PL00353874 A PL 00353874A PL 35387400 A PL35387400 A PL 35387400A PL 353874 A1 PL353874 A1 PL 353874A1
Authority
PL
Poland
Prior art keywords
streptomyces avermitilis
avermitilis
streptomyces
Prior art date
Application number
PL00353874A
Other languages
English (en)
Other versions
PL203818B1 (pl
Inventor
YanChen Yan Chen
ClaesGustafsson Claes Gustafsson
AnkeKrebber Anke Krebber
Jeremy StephenMinshull Jeremy Stephen Minshull
Sun AiRaillard Sun Ai Raillard
Kim JonelleStutzman-Engwall Kim Jonelle Stutzman-Engwall
Original Assignee
Pfizer Products Inc.Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc.Pfizer Products Inc. filed Critical Pfizer Products Inc.Pfizer Products Inc.
Publication of PL353874A1 publication Critical patent/PL353874A1/pl
Publication of PL203818B1 publication Critical patent/PL203818B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL353874A 1999-08-12 2000-07-24 Cząsteczka polinukleotydowa, zrekombinowany wektor, komórka gospodarz Streptomyces, sposób wytwarzania nowego szczepu S. avermitilis, komórka Streptomyces avermitilis, sposób wytwarzania awermektyn i kompozycja awermektyn cykloheksylo-B2:cykloheksylo-B1 PL203818B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14864599P 1999-08-12 1999-08-12
PCT/IB2000/001017 WO2001012821A1 (en) 1999-08-12 2000-07-24 Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins

Publications (2)

Publication Number Publication Date
PL353874A1 true PL353874A1 (pl) 2003-12-01
PL203818B1 PL203818B1 (pl) 2009-11-30

Family

ID=22526696

Family Applications (1)

Application Number Title Priority Date Filing Date
PL353874A PL203818B1 (pl) 1999-08-12 2000-07-24 Cząsteczka polinukleotydowa, zrekombinowany wektor, komórka gospodarz Streptomyces, sposób wytwarzania nowego szczepu S. avermitilis, komórka Streptomyces avermitilis, sposób wytwarzania awermektyn i kompozycja awermektyn cykloheksylo-B2:cykloheksylo-B1

Country Status (39)

Country Link
US (3) US6632673B1 (pl)
EP (1) EP1200606B1 (pl)
JP (1) JP3884651B2 (pl)
KR (1) KR100489856B1 (pl)
CN (1) CN1186446C (pl)
AP (1) AP2002002418A0 (pl)
AR (1) AR022646A1 (pl)
AT (1) ATE341632T1 (pl)
AU (1) AU778837B2 (pl)
BG (1) BG65902B1 (pl)
BR (1) BRPI0013119B8 (pl)
CA (1) CA2380872C (pl)
CO (1) CO5290295A1 (pl)
CY (1) CY1105778T1 (pl)
CZ (1) CZ304402B6 (pl)
DE (1) DE60031126T2 (pl)
DK (1) DK1200606T3 (pl)
EA (1) EA200200056A1 (pl)
ES (1) ES2272299T3 (pl)
GT (1) GT200000136A (pl)
HK (1) HK1046710B (pl)
HR (1) HRP20020130A2 (pl)
HU (1) HU230600B1 (pl)
IL (2) IL147563A0 (pl)
IS (1) IS6250A (pl)
MA (1) MA26813A1 (pl)
MX (1) MXPA02001513A (pl)
NO (1) NO20020664L (pl)
NZ (1) NZ516517A (pl)
OA (1) OA11998A (pl)
PA (1) PA8499501A1 (pl)
PE (1) PE20010690A1 (pl)
PL (1) PL203818B1 (pl)
PT (1) PT1200606E (pl)
SK (1) SK288086B6 (pl)
TN (1) TNSN00171A1 (pl)
UY (1) UY26286A1 (pl)
WO (1) WO2001012821A1 (pl)
ZA (1) ZA200201072B (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2272299T3 (es) * 1999-08-12 2007-05-01 Pfizer Products Inc. Gen de streptomyces avermitilis que dirige la relacion de avermectinas b2:b1.
CN1630712B (zh) 2002-02-12 2011-09-28 辉瑞产品公司 指导b2:b1除虫菌素比例的除虫链霉菌基因
US7943160B2 (en) * 2002-05-09 2011-05-17 Scimetrics Limited Corp. Pest control methods
US9493744B2 (en) * 2012-06-20 2016-11-15 Genentech, Inc. Methods for viral inactivation and other adventitious agents
KR102657859B1 (ko) 2021-04-07 2024-04-16 윤재식 일체형 내화 소켓

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234831A (en) 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
US5525506A (en) 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
IN167980B (pl) * 1987-01-23 1991-01-19 Pfizer
US5238848A (en) 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
ATE89604T1 (de) 1987-10-23 1993-06-15 Pfizer Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen.
US5240850A (en) 1987-10-23 1993-08-31 Pfizer Inc. Cultures for production of avermectin aglycones
US5252474A (en) 1989-03-31 1993-10-12 Merck & Co., Inc. Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use
DE69023036T2 (de) 1989-03-31 1996-06-13 Merck & Co Inc Klonierung von Streptomyces avermitilis Genen zur Biosynthese von Avermectin und Verfahren zu ihrer Verwendung.
BR9407211A (pt) 1993-07-30 1996-09-17 Pfizer Genes codificadores do complexo de desidrogenase de alfa- cetoácidos de cadeia ramificada derivados de streptomyces avermitilis
FI942725L (fi) 1993-12-16 1995-06-17 Pfizer Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6096548A (en) 1996-03-25 2000-08-01 Maxygen, Inc. Method for directing evolution of a virus
WO1998013487A1 (en) 1996-09-27 1998-04-02 Maxygen, Inc. Methods for optimization of gene therapy by recursive sequence shuffling and selection
AU743305C (en) 1997-01-17 2006-03-30 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
EP1030861A4 (en) 1997-10-31 2001-09-05 Maxygen Inc MODIFICATION OF VIRUSTROPISMIUS AND THE ECONOMIC SPECTRUM BY VIRAL GENOM MIXING
US6248579B1 (en) * 1998-02-13 2001-06-19 Pfizer Inc Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins
YU50900A (sh) * 1998-02-13 2004-03-12 Pfizer Produsts Inc. Streptomyces avermitilis gen koji usmerava odnos b2:b1 avermektina
ES2272299T3 (es) * 1999-08-12 2007-05-01 Pfizer Products Inc. Gen de streptomyces avermitilis que dirige la relacion de avermectinas b2:b1.

Also Published As

Publication number Publication date
EP1200606A1 (en) 2002-05-02
HUP0202487A3 (en) 2004-07-28
US20030232415A1 (en) 2003-12-18
CN1186446C (zh) 2005-01-26
SK288086B6 (sk) 2013-06-03
MXPA02001513A (es) 2002-07-02
HU230600B1 (hu) 2017-02-28
EP1200606B1 (en) 2006-10-04
DK1200606T3 (da) 2007-01-08
HK1046710A1 (en) 2003-01-24
CO5290295A1 (es) 2003-06-27
NO20020664D0 (no) 2002-02-11
PT1200606E (pt) 2006-12-29
BRPI0013119B8 (pt) 2021-05-25
SK1392002A3 (en) 2002-12-03
BG106479A (bg) 2002-10-31
OA11998A (en) 2006-04-18
AU778837B2 (en) 2004-12-23
BR0013119A (pt) 2002-04-23
EA200200056A1 (ru) 2002-06-27
MA26813A1 (fr) 2004-12-20
ZA200201072B (en) 2003-04-30
IS6250A (is) 2002-01-25
US7858340B2 (en) 2010-12-28
CY1105778T1 (el) 2011-02-02
PA8499501A1 (es) 2001-12-14
WO2001012821A1 (en) 2001-02-22
CZ304402B6 (cs) 2014-04-16
UY26286A1 (es) 2001-03-16
CZ2002296A3 (cs) 2002-08-14
ES2272299T3 (es) 2007-05-01
BG65902B1 (bg) 2010-04-30
GT200000136A (es) 2002-02-01
CA2380872A1 (en) 2001-02-22
CA2380872C (en) 2007-11-27
DE60031126D1 (de) 2006-11-16
IL147563A (en) 2009-06-15
HUP0202487A2 (en) 2002-10-28
TNSN00171A1 (fr) 2005-11-10
PL203818B1 (pl) 2009-11-30
AP2002002418A0 (en) 2002-03-31
US6632673B1 (en) 2003-10-14
AU5838600A (en) 2001-03-13
NZ516517A (en) 2003-10-31
HK1046710B (zh) 2005-05-13
BR0013119B1 (pt) 2014-02-25
KR100489856B1 (ko) 2005-05-17
NO20020664L (no) 2002-02-11
AR022646A1 (es) 2002-09-04
ATE341632T1 (de) 2006-10-15
US20040009560A1 (en) 2004-01-15
JP2003507017A (ja) 2003-02-25
HRP20020130A2 (en) 2003-06-30
KR20020029379A (ko) 2002-04-18
JP3884651B2 (ja) 2007-02-21
PE20010690A1 (es) 2001-07-06
CN1373809A (zh) 2002-10-09
DE60031126T2 (de) 2007-02-08
IL147563A0 (en) 2002-08-14

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