ATE89604T1 - Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen. - Google Patents
Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen.Info
- Publication number
- ATE89604T1 ATE89604T1 AT88309724T AT88309724T ATE89604T1 AT E89604 T1 ATE89604 T1 AT E89604T1 AT 88309724 T AT88309724 T AT 88309724T AT 88309724 T AT88309724 T AT 88309724T AT E89604 T1 ATE89604 T1 AT E89604T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- aglycones
- avermectin
- cultures containing
- natural
- Prior art date
Links
- 239000005660 Abamectin Substances 0.000 title abstract 3
- RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 title abstract 2
- 108010046716 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide) Proteins 0.000 abstract 1
- 241001468227 Streptomyces avermitilis Species 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000000590 parasiticidal effect Effects 0.000 abstract 1
- 239000002297 parasiticide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11297287A | 1987-10-23 | 1987-10-23 | |
| EP88309724A EP0313297B1 (de) | 1987-10-23 | 1988-10-17 | Verfahren zur Herstellung von Aglykonen von Avermectin und sie enthaltende Kulturen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE89604T1 true ATE89604T1 (de) | 1993-06-15 |
Family
ID=22346865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88309724T ATE89604T1 (de) | 1987-10-23 | 1988-10-17 | Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0313297B1 (de) |
| JP (1) | JPH06104058B2 (de) |
| AT (1) | ATE89604T1 (de) |
| CA (1) | CA1337757C (de) |
| DE (1) | DE3881147T2 (de) |
| DK (1) | DK586988A (de) |
| ES (1) | ES2054822T3 (de) |
| IE (1) | IE61806B1 (de) |
| PT (1) | PT88826B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2888586B2 (ja) * | 1990-03-05 | 1999-05-10 | 社団法人北里研究所 | エバーメクチンの特定成分を選択生産するための微生物およびその選択的製造法 |
| FI942725L (fi) * | 1993-12-16 | 1995-06-17 | Pfizer | Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta |
| US6248579B1 (en) | 1998-02-13 | 2001-06-19 | Pfizer Inc | Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins |
| SK11722000A3 (sk) * | 1998-02-13 | 2001-04-09 | Pfizer Products Inc. | Gén streptomyces avermitilis riadici pomer b2 : b1 avermektínov |
| US6197591B1 (en) | 1998-09-14 | 2001-03-06 | Pfizer Inc. | Streptomyces avermitilis regulatory genes for increased avermectin production |
| HRP20020130A2 (en) | 1999-08-12 | 2003-06-30 | Pfizer Prod Inc | Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE434277B (sv) | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
| US4429042A (en) | 1978-09-08 | 1984-01-31 | Merck & Co., Inc. | Strain of Streptomyces for producing antiparasitic compounds |
| ES8800986A1 (es) * | 1985-07-27 | 1987-12-01 | Pfizer | Un procedimiento para la produccion de un nuevo derivado de avermectina |
| IN167980B (de) * | 1987-01-23 | 1991-01-19 | Pfizer | |
| DE3883408T2 (de) * | 1987-01-23 | 1993-12-09 | Pfizer | Verfahren zur Herstellung von Avermectinen und die verwendeten Kulturen. |
-
1988
- 1988-10-17 ES ES88309724T patent/ES2054822T3/es not_active Expired - Lifetime
- 1988-10-17 DE DE8888309724T patent/DE3881147T2/de not_active Expired - Fee Related
- 1988-10-17 AT AT88309724T patent/ATE89604T1/de not_active IP Right Cessation
- 1988-10-17 EP EP88309724A patent/EP0313297B1/de not_active Expired - Lifetime
- 1988-10-21 IE IE319288A patent/IE61806B1/en not_active IP Right Cessation
- 1988-10-21 CA CA000580988A patent/CA1337757C/en not_active Expired - Fee Related
- 1988-10-21 DK DK586988A patent/DK586988A/da not_active Application Discontinuation
- 1988-10-21 PT PT88826A patent/PT88826B/pt not_active IP Right Cessation
- 1988-10-21 JP JP63265943A patent/JPH06104058B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0313297B1 (de) | 1993-05-19 |
| ES2054822T3 (es) | 1994-08-16 |
| DK586988A (da) | 1989-06-14 |
| IE883192L (en) | 1989-04-23 |
| JPH06104058B2 (ja) | 1994-12-21 |
| IE61806B1 (en) | 1994-11-30 |
| EP0313297A3 (en) | 1990-07-25 |
| DE3881147T2 (de) | 1993-09-02 |
| DE3881147D1 (de) | 1993-06-24 |
| JPH01153083A (ja) | 1989-06-15 |
| PT88826B (pt) | 1993-01-29 |
| DK586988D0 (da) | 1988-10-21 |
| CA1337757C (en) | 1995-12-19 |
| EP0313297A2 (de) | 1989-04-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY103514A (en) | Process for production of a avermectins and cultures therefor. | |
| MY102581A (en) | Process for production of avermectins and cultures therefor | |
| AU9058091A (en) | Preparation of nucleic acid samples | |
| AU7346087A (en) | Bioreactor for cultivation of microorganisms | |
| DE3856477D1 (de) | Verfahren zur Herstellung von 2'-deoxy-2',2'-difluornukleosiden | |
| BR8501374A (pt) | Microorganismos capazes de produzir l-carnitina e processo para preparacao de l-carnitina | |
| ATE89604T1 (de) | Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen. | |
| NO842546L (no) | Antracycylinderivater, en mikrobiologisk fremgangsmaate til deres fremstilling og deres anvendelse som cytostatika | |
| DE3888587D1 (de) | AB-006-Antibiotika und Verfahren zu deren Herstellung. | |
| DE69232259D1 (de) | Verfahren zur Herstellung von Interleukin-6 Zusammensetzungen | |
| ATE81341T1 (de) | Verfahren zur herstellung von antibiotica 10381b. | |
| ATE34176T1 (de) | 2'-chloropentostatin, eine diese verbindung enthaltende pharmazeutische zusammensetzung und ein mikroorganismus zur herstellung dieser verbindung. | |
| PT87092A (pt) | Process for the preparation of milbemycin derivatives useful as parasiticides and insecticides | |
| DE69225610D1 (de) | Verfahren zur herstellung von avermectin und kulturen dafür | |
| DK684987A (da) | Amycin og derivater deraf, fremgangsmaade til deres fremstilling og deres anvendelse samt mikroorganisme | |
| PT83534A (de) | Verfahren zur herstellung von cholesterinoxidase durch fermentation von streptomyces hydrogenans | |
| EP0318060A3 (en) | Griseolic acid derivatives, their preparation and their use | |
| PT80357A (de) | Mikrobiologisches verfahren zur herstellung von anthracyclin-derivaten | |
| AU603415C (en) | Process for production of avermectins and cultures therefor | |
| AU603416C (en) | Process for production of B avermectins and cultures therefor | |
| ATE15694T1 (de) | Verfahren zur herstellung eines immobilisierten enzymsystems und reinigung von glucose-isomerase. | |
| BG60106B2 (bg) | Метод за култивиране на водорасли | |
| JPS54154598A (en) | Method of increasing the yield of antibiotics |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |