BR0013119A - Gene de streptomyces avermitilis que regula a proporção de avermectinas b2:bl - Google Patents
Gene de streptomyces avermitilis que regula a proporção de avermectinas b2:blInfo
- Publication number
- BR0013119A BR0013119A BR0013119-9A BR0013119A BR0013119A BR 0013119 A BR0013119 A BR 0013119A BR 0013119 A BR0013119 A BR 0013119A BR 0013119 A BR0013119 A BR 0013119A
- Authority
- BR
- Brazil
- Prior art keywords
- avermectins
- proportion
- regulates
- ratio
- streptomyces avermitilis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14864599P | 1999-08-12 | 1999-08-12 | |
US60/148,645 | 1999-08-12 | ||
PCT/IB2000/001017 WO2001012821A1 (en) | 1999-08-12 | 2000-07-24 | Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0013119A true BR0013119A (pt) | 2002-04-23 |
BR0013119B1 BR0013119B1 (pt) | 2014-02-25 |
BRPI0013119B8 BRPI0013119B8 (pt) | 2021-05-25 |
Family
ID=22526696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0013119A BRPI0013119B8 (pt) | 1999-08-12 | 2000-07-24 | molécula polinucleotídica isolada, vetor recombinante purificado, célula hospedeira procariótica e célula de streptomyces avermitilis mutada, método para obtenção de uma nova cepa de s. avermitilis e processo para produção de avermectinas |
Country Status (39)
Country | Link |
---|---|
US (3) | US6632673B1 (pt) |
EP (1) | EP1200606B1 (pt) |
JP (1) | JP3884651B2 (pt) |
KR (1) | KR100489856B1 (pt) |
CN (1) | CN1186446C (pt) |
AP (1) | AP2002002418A0 (pt) |
AR (1) | AR022646A1 (pt) |
AT (1) | ATE341632T1 (pt) |
AU (1) | AU778837B2 (pt) |
BG (1) | BG65902B1 (pt) |
BR (1) | BRPI0013119B8 (pt) |
CA (1) | CA2380872C (pt) |
CO (1) | CO5290295A1 (pt) |
CY (1) | CY1105778T1 (pt) |
CZ (1) | CZ304402B6 (pt) |
DE (1) | DE60031126T2 (pt) |
DK (1) | DK1200606T3 (pt) |
EA (1) | EA200200056A1 (pt) |
ES (1) | ES2272299T3 (pt) |
GT (1) | GT200000136A (pt) |
HK (1) | HK1046710B (pt) |
HR (1) | HRP20020130A2 (pt) |
HU (1) | HU230600B1 (pt) |
IL (2) | IL147563A0 (pt) |
IS (1) | IS6250A (pt) |
MA (1) | MA26813A1 (pt) |
MX (1) | MXPA02001513A (pt) |
NO (1) | NO20020664D0 (pt) |
NZ (1) | NZ516517A (pt) |
OA (1) | OA11998A (pt) |
PA (1) | PA8499501A1 (pt) |
PE (1) | PE20010690A1 (pt) |
PL (1) | PL203818B1 (pt) |
PT (1) | PT1200606E (pt) |
SK (1) | SK288086B6 (pt) |
TN (1) | TNSN00171A1 (pt) |
UY (1) | UY26286A1 (pt) |
WO (1) | WO2001012821A1 (pt) |
ZA (1) | ZA200201072B (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3884651B2 (ja) * | 1999-08-12 | 2007-02-21 | ファイザー・プロダクツ・インク | B2アベルメクチン:b1アベルメクチンの比を指示するストレプトミセス・アベルミティリス遺伝子 |
RU2293117C2 (ru) * | 2002-02-12 | 2007-02-10 | Пфайзер Продактс Инк. | Ген streptomyces avermitilis и его применение для изменения соотношения авермектинов b2:b1 |
US7943160B2 (en) * | 2002-05-09 | 2011-05-17 | Scimetrics Limited Corp. | Pest control methods |
US9493744B2 (en) | 2012-06-20 | 2016-11-15 | Genentech, Inc. | Methods for viral inactivation and other adventitious agents |
KR102657859B1 (ko) | 2021-04-07 | 2024-04-16 | 윤재식 | 일체형 내화 소켓 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5525506A (en) | 1987-01-23 | 1996-06-11 | Pfizer Inc. | Process for production of avermectins and cultures therefor |
US5238848A (en) | 1987-01-23 | 1993-08-24 | Pfizer Inc | Cultures for production of avermectins |
IN167980B (pt) * | 1987-01-23 | 1991-01-19 | Pfizer | |
US5234831A (en) | 1987-01-23 | 1993-08-10 | Pfizer Inc | Cultures for production of B avermectins |
ES2054822T3 (es) | 1987-10-23 | 1994-08-16 | Pfizer | Procedimiento para la produccion de agliconas de avermectinas y sus cultivos. |
US5240850A (en) | 1987-10-23 | 1993-08-31 | Pfizer Inc. | Cultures for production of avermectin aglycones |
DE69023036T2 (de) | 1989-03-31 | 1996-06-13 | Merck & Co Inc | Klonierung von Streptomyces avermitilis Genen zur Biosynthese von Avermectin und Verfahren zu ihrer Verwendung. |
US5252474A (en) | 1989-03-31 | 1993-10-12 | Merck & Co., Inc. | Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
WO1995004150A1 (en) | 1993-07-30 | 1995-02-09 | Pfizer Inc. | Genes encoding branched-chain alpha-ketoacid dehydrogenase complex from streptomyces avermitilis |
FI942725A (fi) | 1993-12-16 | 1995-06-17 | Pfizer | Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta |
US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
US6335160B1 (en) | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
US5837458A (en) | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
US6117679A (en) | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
US6096548A (en) | 1996-03-25 | 2000-08-01 | Maxygen, Inc. | Method for directing evolution of a virus |
EP0964922A4 (en) | 1996-09-27 | 2000-10-25 | Maxygen Inc | METHOD FOR OPTIMIZING GENE THERAPY BY REPEATING SEQUENCE MIXING AND SELECTION |
EP1007732B1 (en) | 1997-01-17 | 2006-07-26 | Maxygen, Inc. | EVOLUTION OF procaryotic WHOLE CELLS BY RECURSIVE SEQUENCE RECOMBINATION |
EP1030861A4 (en) | 1997-10-31 | 2001-09-05 | Maxygen Inc | MODIFICATION OF VIRAL TROPISM AND THE DIVERSITY OF HOST SPECIES BY RECOMBINATION OF THE VIRAL GENOME |
US6248579B1 (en) * | 1998-02-13 | 2001-06-19 | Pfizer Inc | Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins |
BR9907893A (pt) * | 1998-02-13 | 2000-11-14 | Pfizer Prod Inc | Gene de streptomyces avermitilis que dirige a proporção de avermectinas b2:b1 |
JP3884651B2 (ja) * | 1999-08-12 | 2007-02-21 | ファイザー・プロダクツ・インク | B2アベルメクチン:b1アベルメクチンの比を指示するストレプトミセス・アベルミティリス遺伝子 |
-
2000
- 2000-07-24 JP JP2001516908A patent/JP3884651B2/ja not_active Expired - Lifetime
- 2000-07-24 CZ CZ2002-296A patent/CZ304402B6/cs not_active IP Right Cessation
- 2000-07-24 SK SK139-2002A patent/SK288086B6/sk not_active IP Right Cessation
- 2000-07-24 PT PT00944154T patent/PT1200606E/pt unknown
- 2000-07-24 NZ NZ516517A patent/NZ516517A/en unknown
- 2000-07-24 DK DK00944154T patent/DK1200606T3/da active
- 2000-07-24 ES ES00944154T patent/ES2272299T3/es not_active Expired - Lifetime
- 2000-07-24 WO PCT/IB2000/001017 patent/WO2001012821A1/en active Application Filing
- 2000-07-24 AU AU58386/00A patent/AU778837B2/en not_active Expired
- 2000-07-24 CN CNB008117470A patent/CN1186446C/zh not_active Expired - Lifetime
- 2000-07-24 DE DE60031126T patent/DE60031126T2/de not_active Expired - Lifetime
- 2000-07-24 AT AT00944154T patent/ATE341632T1/de active
- 2000-07-24 CA CA002380872A patent/CA2380872C/en not_active Expired - Lifetime
- 2000-07-24 EA EA200200056A patent/EA200200056A1/ru unknown
- 2000-07-24 HU HU0202487A patent/HU230600B1/hu unknown
- 2000-07-24 PL PL353874A patent/PL203818B1/pl unknown
- 2000-07-24 KR KR10-2002-7001807A patent/KR100489856B1/ko active IP Right Grant
- 2000-07-24 BR BRPI0013119A patent/BRPI0013119B8/pt not_active IP Right Cessation
- 2000-07-24 EP EP00944154A patent/EP1200606B1/en not_active Expired - Lifetime
- 2000-07-24 OA OA1200200025A patent/OA11998A/en unknown
- 2000-07-24 AP APAP/P/2002/002418A patent/AP2002002418A0/en unknown
- 2000-07-24 IL IL14756300A patent/IL147563A0/xx unknown
- 2000-07-24 MX MXPA02001513A patent/MXPA02001513A/es active IP Right Grant
- 2000-08-04 CO CO00058605A patent/CO5290295A1/es not_active Application Discontinuation
- 2000-08-10 UY UY26286A patent/UY26286A1/es not_active Application Discontinuation
- 2000-08-10 GT GT200000136A patent/GT200000136A/es unknown
- 2000-08-10 US US09/637,040 patent/US6632673B1/en not_active Expired - Lifetime
- 2000-08-10 PA PA20008499501A patent/PA8499501A1/es unknown
- 2000-08-10 AR ARP000104131A patent/AR022646A1/es active IP Right Grant
- 2000-08-10 PE PE2000000812A patent/PE20010690A1/es not_active Application Discontinuation
- 2000-08-11 TN TNTNSN00171A patent/TNSN00171A1/fr unknown
-
2002
- 2002-01-10 IL IL147563A patent/IL147563A/en active IP Right Grant
- 2002-01-25 IS IS6250A patent/IS6250A/is unknown
- 2002-02-07 MA MA26513A patent/MA26813A1/fr unknown
- 2002-02-07 ZA ZA200201072A patent/ZA200201072B/en unknown
- 2002-02-11 NO NO20020664A patent/NO20020664D0/no not_active Application Discontinuation
- 2002-02-12 HR HR20020130A patent/HRP20020130A2/hr not_active Application Discontinuation
- 2002-03-05 BG BG106479A patent/BG65902B1/bg unknown
- 2002-11-19 HK HK02108367.6A patent/HK1046710B/zh unknown
-
2003
- 2003-06-11 US US10/412,450 patent/US7858340B2/en not_active Expired - Fee Related
- 2003-06-11 US US10/412,444 patent/US20040009560A1/en not_active Abandoned
-
2006
- 2006-11-13 CY CY20061101647T patent/CY1105778T1/el unknown
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Legal Events
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B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B25A | Requested transfer of rights approved |
Owner name: PAH USA 15 LLC (US) |
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