PL353770A1 - Gen Streptomyces avermitilis decydujący o stosunkuGen Streptomyces avermitilis decydujący o stosunku awermektyn B1:B2 awermektyn B1:B2 - Google Patents

Gen Streptomyces avermitilis decydujący o stosunkuGen Streptomyces avermitilis decydujący o stosunku awermektyn B1:B2 awermektyn B1:B2

Info

Publication number
PL353770A1
PL353770A1 PL00353770A PL35377000A PL353770A1 PL 353770 A1 PL353770 A1 PL 353770A1 PL 00353770 A PL00353770 A PL 00353770A PL 35377000 A PL35377000 A PL 35377000A PL 353770 A1 PL353770 A1 PL 353770A1
Authority
PL
Poland
Prior art keywords
streptomyces avermitilis
avermitilis
streptomyces
Prior art date
Application number
PL00353770A
Other languages
English (en)
Inventor
Kim JonelleStutzman-Engwall Kim Jonelle Stutzman-Engwall
Original Assignee
Pfizer Products Inc.Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc.Pfizer Products Inc. filed Critical Pfizer Products Inc.Pfizer Products Inc.
Publication of PL353770A1 publication Critical patent/PL353770A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623Avermectin; Milbemycin; Ivermectin; C-076

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL00353770A 1999-08-12 2000-07-19 Gen Streptomyces avermitilis decydujący o stosunkuGen Streptomyces avermitilis decydujący o stosunku awermektyn B1:B2 awermektyn B1:B2 PL353770A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/372,934 US6248579B1 (en) 1998-02-13 1999-08-12 Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins
PCT/IB2000/000996 WO2001012822A1 (en) 1999-08-12 2000-07-19 Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins

Publications (1)

Publication Number Publication Date
PL353770A1 true PL353770A1 (pl) 2003-12-01

Family

ID=23470234

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00353770A PL353770A1 (pl) 1999-08-12 2000-07-19 Gen Streptomyces avermitilis decydujący o stosunkuGen Streptomyces avermitilis decydujący o stosunku awermektyn B1:B2 awermektyn B1:B2

Country Status (37)

Country Link
US (8) US6248579B1 (pl)
EP (1) EP1200605B1 (pl)
JP (2) JP3688640B2 (pl)
KR (1) KR100486006B1 (pl)
CN (1) CN1186447C (pl)
AP (2) AP2002002417A0 (pl)
AR (1) AR021450A1 (pl)
AT (1) ATE283363T1 (pl)
AU (1) AU779756B2 (pl)
BG (1) BG106478A (pl)
BR (1) BR0013093A (pl)
CA (1) CA2381427A1 (pl)
CO (1) CO5290296A1 (pl)
CZ (1) CZ2002297A3 (pl)
DE (1) DE60016231T2 (pl)
EA (1) EA004569B1 (pl)
ES (1) ES2231214T3 (pl)
GT (2) GT200000138CA (pl)
HK (1) HK1046536B (pl)
HR (1) HRP20020131A2 (pl)
HU (1) HUP0202517A2 (pl)
IL (1) IL147562A0 (pl)
IS (1) IS6249A (pl)
MA (1) MA26811A1 (pl)
MX (1) MXPA02001514A (pl)
NO (1) NO20020665D0 (pl)
OA (1) OA11997A (pl)
PA (1) PA8499201A1 (pl)
PE (1) PE20010697A1 (pl)
PL (1) PL353770A1 (pl)
PT (1) PT1200605E (pl)
SK (1) SK1382002A3 (pl)
TN (1) TNSN00170A1 (pl)
UY (1) UY26287A1 (pl)
WO (1) WO2001012822A1 (pl)
YU (1) YU8402A (pl)
ZA (1) ZA200201071B (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2272299T3 (es) * 1999-08-12 2007-05-01 Pfizer Products Inc. Gen de streptomyces avermitilis que dirige la relacion de avermectinas b2:b1.
ATE373644T1 (de) 2002-02-05 2007-10-15 Bristol Myers Squibb Co N-substituierte 3-hydroxy-4-pyridinone und diese enthaltende pharmazeutika
CN1630712B (zh) 2002-02-12 2011-09-28 辉瑞产品公司 指导b2:b1除虫菌素比例的除虫链霉菌基因
US7943160B2 (en) * 2002-05-09 2011-05-17 Scimetrics Limited Corp. Pest control methods
WO2004067549A2 (de) * 2003-01-31 2004-08-12 Max-Delbrück-Centrum für Molekulare Medizin Peptide gegen kälteunverträglichkeit hervorrufende autoantikörper und ihre verwendung
KR100759130B1 (ko) 2005-02-12 2007-09-19 휴메드 주식회사 항 인테그린 항체 코팅스텐트 및 그의 제조방법
CN106148216B (zh) 2015-03-27 2019-06-04 浙江海正药业股份有限公司 一种链霉菌及其生产米尔贝霉素a3的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5238848A (en) 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
US5234831A (en) 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
US5525506A (en) 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
US5240850A (en) 1987-10-23 1993-08-31 Pfizer Inc. Cultures for production of avermectin aglycones
ATE89604T1 (de) 1987-10-23 1993-06-15 Pfizer Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen.
DE69023036T2 (de) 1989-03-31 1996-06-13 Merck & Co Inc Klonierung von Streptomyces avermitilis Genen zur Biosynthese von Avermectin und Verfahren zu ihrer Verwendung.
US5252474A (en) 1989-03-31 1993-10-12 Merck & Co., Inc. Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use
BR9407211A (pt) 1993-07-30 1996-09-17 Pfizer Genes codificadores do complexo de desidrogenase de alfa- cetoácidos de cadeia ramificada derivados de streptomyces avermitilis
US5665708A (en) * 1993-10-05 1997-09-09 Pfizer Inc. Process and antiparasitic intermediates for doramectin
FI942725L (fi) 1993-12-16 1995-06-17 Pfizer Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta
YU50900A (sh) * 1998-02-13 2004-03-12 Pfizer Produsts Inc. Streptomyces avermitilis gen koji usmerava odnos b2:b1 avermektina

Also Published As

Publication number Publication date
PE20010697A1 (es) 2001-07-05
NO20020665L (no) 2002-02-11
WO2001012822A1 (en) 2001-02-22
US7259241B2 (en) 2007-08-21
SK1382002A3 (en) 2002-11-06
AP2002002419A0 (en) 2002-03-31
AP2002002417A0 (en) 2002-03-31
US20030124607A1 (en) 2003-07-03
US20030129635A1 (en) 2003-07-10
TNSN00170A1 (fr) 2005-11-10
EP1200605B1 (en) 2004-11-24
UY26287A1 (es) 2001-03-16
AU779756B2 (en) 2005-02-10
EA004569B1 (ru) 2004-06-24
MA26811A1 (fr) 2004-12-20
ES2231214T3 (es) 2005-05-16
US20050196777A1 (en) 2005-09-08
JP2003507018A (ja) 2003-02-25
US20010024818A1 (en) 2001-09-27
US20030134313A1 (en) 2003-07-17
US7029887B2 (en) 2006-04-18
AR021450A1 (es) 2002-07-17
JP2005198658A (ja) 2005-07-28
HUP0202517A2 (hu) 2002-11-28
MXPA02001514A (es) 2002-07-02
PT1200605E (pt) 2005-04-29
IL147562A0 (en) 2002-08-14
NO20020665D0 (no) 2002-02-11
HRP20020131A2 (en) 2003-12-31
KR100486006B1 (ko) 2005-05-03
US6509159B2 (en) 2003-01-21
DE60016231T2 (de) 2005-12-08
KR20020022809A (ko) 2002-03-27
CN1186447C (zh) 2005-01-26
ZA200201071B (en) 2003-06-25
CO5290296A1 (es) 2003-06-27
JP3688640B2 (ja) 2005-08-31
PA8499201A1 (es) 2001-12-14
BR0013093A (pt) 2002-08-13
DE60016231D1 (de) 2004-12-30
US20030129636A1 (en) 2003-07-10
US6511841B2 (en) 2003-01-28
US6833263B2 (en) 2004-12-21
IS6249A (is) 2002-01-25
AU5702100A (en) 2001-03-13
EP1200605A1 (en) 2002-05-02
CN1370239A (zh) 2002-09-18
CA2381427A1 (en) 2001-02-22
EA200200057A1 (ru) 2002-06-27
US20010016350A1 (en) 2001-08-23
US6248579B1 (en) 2001-06-19
HK1046536B (zh) 2005-05-13
ATE283363T1 (de) 2004-12-15
HK1046536A1 (en) 2003-01-17
YU8402A (sh) 2006-03-03
OA11997A (en) 2006-04-18
GT200000138CA (es) 2002-02-02
GT200000138A (es) 2002-02-02
BG106478A (bg) 2004-02-27
CZ2002297A3 (cs) 2002-08-14

Similar Documents

Publication Publication Date Title
AU1727702A (en) Macrolide antibiotics
AU2002217277A1 (en) Macrolide antibiotics
PL348333A1 (en) Macrolides
AU6306100A (en) Improved passage-travelling device
IL144178A0 (en) Ketolide antibiotics
HUP0203707A3 (en) Oligosaccharide mixture
AP2002002396A0 (en) Lottery system
AU2001272719A1 (en) Macrolide antibiotics
IL142628A0 (en) Novel macrolide antibiotics
NZ513998A (en) Erythromycin derivatives
AU2002221895A1 (en) Macrolide solvates
EP1185802A4 (en) TRANSMISSION
PL353770A1 (pl) Gen Streptomyces avermitilis decydujący o stosunkuGen Streptomyces avermitilis decydujący o stosunku awermektyn B1:B2 awermektyn B1:B2
AU5789001A (en) Macrolide antiinfective agents
AU6842700A (en) Shuttle-cock shaped device
GB2356149B (en) Lottery system
PL353874A1 (pl) Gen Streptomyces avermitilis decydujący o stosunkuGen Streptomyces avermitilis decydujący o stosunku awermektyn B1:B2 awermektyn B1:B2
AU2002230386A1 (en) Sixteen-membered macrolide compounds
GB9914346D0 (en) Antibiotic agents
AU2796700A (en) 4-phenoxymethyl-substituted milbemycins
AU2283399A (en) Game device
GB9914348D0 (en) Antibiotic agents
GB9809219D0 (en) Antibiotic agents
HK1059623A (en) Macrolide solvates
PL332809A1 (en) Console

Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)