PL3068764T3 - Sposób fluorowania związków - Google Patents

Sposób fluorowania związków

Info

Publication number
PL3068764T3
PL3068764T3 PL14805449T PL14805449T PL3068764T3 PL 3068764 T3 PL3068764 T3 PL 3068764T3 PL 14805449 T PL14805449 T PL 14805449T PL 14805449 T PL14805449 T PL 14805449T PL 3068764 T3 PL3068764 T3 PL 3068764T3
Authority
PL
Poland
Prior art keywords
fluorinating compounds
fluorinating
compounds
Prior art date
Application number
PL14805449T
Other languages
English (en)
Inventor
Laura Allen
Melanie SANFORD
Shin Hee Lee
Douglas Bland
Yang Cheng
Gary Roth
Joseck MUHUHI
Original Assignee
Dow Agrosciences Llc
The Regents Of The University Of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc, The Regents Of The University Of Michigan filed Critical Dow Agrosciences Llc
Publication of PL3068764T3 publication Critical patent/PL3068764T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/803Processes of preparation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/127Preparation from compounds containing pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PL14805449T 2013-11-12 2014-11-12 Sposób fluorowania związków PL3068764T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361902989P 2013-11-12 2013-11-12
PCT/US2014/065199 WO2015073525A1 (en) 2013-11-12 2014-11-12 Process for fluorinating compounds
EP14805449.7A EP3068764B1 (en) 2013-11-12 2014-11-12 Process for fluorinating compounds

Publications (1)

Publication Number Publication Date
PL3068764T3 true PL3068764T3 (pl) 2019-08-30

Family

ID=51999557

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14805449T PL3068764T3 (pl) 2013-11-12 2014-11-12 Sposób fluorowania związków

Country Status (14)

Country Link
US (1) US9493415B2 (pl)
EP (1) EP3068764B1 (pl)
JP (1) JP6563391B2 (pl)
CN (1) CN105899488B (pl)
AR (1) AR098398A1 (pl)
BR (1) BR102014028162A2 (pl)
CA (1) CA2929940A1 (pl)
ES (1) ES2720234T3 (pl)
HU (1) HUE043300T2 (pl)
IL (1) IL245542B (pl)
PL (1) PL3068764T3 (pl)
TW (1) TW201609652A (pl)
UY (1) UY35831A (pl)
WO (1) WO2015073525A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201609651A (zh) 2013-11-12 2016-03-16 陶氏農業科學公司 用於氟化化合物之過程(一)
BR102014028164A2 (pt) * 2013-11-12 2015-09-08 Dow Agrosciences Llc processo para fluoração de compostos
TWI726900B (zh) 2015-08-04 2021-05-11 美商陶氏農業科學公司 用於氟化化合物之過程

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GB8504268D0 (en) * 1985-02-19 1985-03-20 Shell Int Research Preparation of fluorinated pyridines
DE3827436A1 (de) * 1988-08-12 1990-02-15 Bayer Ag Verfahren zum einfuehren von fluoratomen an aromatische kerne durch nucleophilen austausch
EP0523671B1 (de) * 1991-07-17 1996-01-17 Hoechst Aktiengesellschaft Verfahren zur Herstellung von Chlorfluornitrobenzolen
CA2290712C (en) * 1995-09-22 2003-09-09 Wakunaga Pharmaceutical Co., Ltd. Novel pyridonecarboxylic acid derivatives or their salts, and antibacterial agents containing the same as their effective components
DE19817264A1 (de) * 1998-04-18 1999-10-21 Bayer Ag Neue Dihydropyrimidine
CA2445459A1 (fr) 2001-05-17 2002-11-21 Maxime Garayt Utilisation d'une composition de nature ionique comme reactif de substitution, composition constituant un reactif de fluoration et procede l'utilisant
CN1357530A (zh) * 2001-07-23 2002-07-10 昆山双鹤药业有限责任公司 用邻氯硝基苯制备2,3,4-三氟硝基苯的生产工艺
KR100441153B1 (ko) 2002-03-14 2004-07-21 주식회사 씨트리 유기 불소화합물의 제조방법
DE10227223A1 (de) 2002-06-18 2004-01-08 Kühlein, Klaus, Prof.Dr. Verfahren zur Herstellung substituierter organischer Verbindungen und Verwendung von Katalysatoren für Substitutionsreaktionen
WO2004048350A2 (en) 2002-11-28 2004-06-10 Astrazeneca Ab Oxazolidinones as antibacterial agents
EP1698606B1 (en) 2003-12-25 2013-02-20 Sumitomo Chemical Company, Limited Fluorinating agent and method for producing fluorine-containing compound using same
DE102004033525A1 (de) 2004-07-08 2006-02-02 Lanxess Deutschland Gmbh Verbessertes Verfahren zur Herstellung kernfluorierter Aromaten
US7592486B2 (en) 2004-09-16 2009-09-22 Board Of Regents Of The University Of Nebraska Anhydrous fluoride salts and reagents and methods for their production
ES2402145T3 (es) 2004-11-17 2013-04-29 Piramal Critical Care, Inc. Procedimiento para la preparación de sevoflurano
CN100344605C (zh) * 2006-06-30 2007-10-24 上海万溯化学有限公司 一种3-氟-5-硝基三氟甲苯的制备方法
AR068509A1 (es) * 2007-09-19 2009-11-18 Jerini Ag Antagosnistas del receptor de bradiquinina b1
CN101591211B (zh) * 2008-05-30 2012-10-03 南京理工大学 微波卤素交换氟化制备氟代化合物的方法
CN101519373B (zh) * 2008-12-30 2011-10-05 凯莱英医药化学(天津)有限公司 一种2,6-二氟吡啶的合成方法
CN101602712B (zh) * 2009-07-21 2011-04-06 南京第一农药集团有限公司 一种合成2-氟-3-氯-5-三氟甲基吡啶的方法
CN101648904B (zh) * 2009-09-14 2011-08-03 南京第一农药集团有限公司 一种2,3-二氟-5-氯吡啶的合成方法
CN101671217A (zh) * 2009-09-28 2010-03-17 南京第一农药集团有限公司 由有机多氯化合物制备有机氟氯化合物的方法
CN102531962A (zh) * 2010-12-30 2012-07-04 上海恩氟佳科技有限公司 2-氟-5-氯苯腈的制备方法
TWI537252B (zh) 2011-01-25 2016-06-11 陶氏農業科學公司 用於製備4-胺基-5-氟-3-鹵素-6-(經取代之)吡啶甲酸酯的方法(一)
TWI592401B (zh) 2011-01-25 2017-07-21 陶氏農業科學公司 用於製備4-胺基-3-氯-5-氟-6-(經取代的)吡啶甲酸酯的方法(一)
TWI529163B (zh) 2011-01-25 2016-04-11 陶氏農業科學公司 用於製備4-胺基-5-氟-3-鹵素-6-(經取代之)吡啶甲酸酯的方法
TWI520943B (zh) 2011-01-25 2016-02-11 陶氏農業科學公司 用於製備4-胺基-3-氯-5-氟-6-(經取代的)吡啶甲酸酯的方法(二)
FR2975990B1 (fr) 2011-06-01 2013-05-24 Rhodia Operations Procede de preparation d'un compose organique fluore
CN102617360B (zh) * 2012-03-01 2013-11-06 江西吉翔医药化工有限公司 3,5-二氯-2,4-二氟苯胺的合成方法
AR091856A1 (es) 2012-07-24 2015-03-04 Dow Agrosciences Llc Proceso para la preparacion de 4-amino-5-fluor-3-halo-6-(substituido) picolinatos
AR092355A1 (es) 2012-07-24 2015-04-15 Dow Agrosciences Llc Fluoruros de fluoropicolinoilo y procesos para su preparacion
CN103012279B (zh) * 2012-11-27 2015-01-28 浙江工业大学 一种4,5,6-三氟嘧啶化合物的制备方法
BR102013032022A2 (pt) 2012-12-13 2014-10-21 Dow Agrosciences Llc Processo para a preparação de 4-amino-5-fluoro-3-cloro-6-(substituído)picolinatos
WO2014093591A1 (en) 2012-12-13 2014-06-19 Dow Agrosciences Llc Processes for the preparation of 4-amino-3-halo-6- (substituted)picolinates and 4-amino-5-fluoro-3-halo-6- (substituted)picolinates
PL2931043T3 (pl) 2012-12-13 2018-01-31 Dow Agrosciences Llc Sposób wytwarzania 4-amino-5-fluoro-3-chloro 6-(podstawionych) pikolinianów
TW201609651A (zh) 2013-11-12 2016-03-16 陶氏農業科學公司 用於氟化化合物之過程(一)
BR102014028164A2 (pt) 2013-11-12 2015-09-08 Dow Agrosciences Llc processo para fluoração de compostos

Also Published As

Publication number Publication date
BR102014028162A2 (pt) 2015-09-08
US9493415B2 (en) 2016-11-15
AR098398A1 (es) 2016-05-26
HUE043300T2 (hu) 2019-08-28
JP6563391B2 (ja) 2019-08-21
CN105899488A (zh) 2016-08-24
JP2016538278A (ja) 2016-12-08
TW201609652A (zh) 2016-03-16
CA2929940A1 (en) 2015-05-21
WO2015073525A1 (en) 2015-05-21
IL245542B (en) 2019-01-31
IL245542A0 (en) 2016-06-30
US20150141654A1 (en) 2015-05-21
UY35831A (es) 2015-06-30
EP3068764A1 (en) 2016-09-21
CN105899488B (zh) 2019-09-03
ES2720234T3 (es) 2019-07-18
EP3068764B1 (en) 2019-02-20

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