PL3020729T3 - Przeciwciała przeciw ludzkiej il-22 i ich zastosowania - Google Patents

Przeciwciała przeciw ludzkiej il-22 i ich zastosowania

Info

Publication number
PL3020729T3
PL3020729T3 PL15184078T PL15184078T PL3020729T3 PL 3020729 T3 PL3020729 T3 PL 3020729T3 PL 15184078 T PL15184078 T PL 15184078T PL 15184078 T PL15184078 T PL 15184078T PL 3020729 T3 PL3020729 T3 PL 3020729T3
Authority
PL
Poland
Prior art keywords
antibodies against
against human
uses therefor
therefor
human
Prior art date
Application number
PL15184078T
Other languages
English (en)
Inventor
Jing Li
Ralph R. Minter
Davinder S. Gill
Geertruida M. Veldman
Lynette A. Fouser
Viia Valge-Archer
David C. Lowe
Caroline S. Russell
Suzanne E. Cohen
Albert B. Thom
Original Assignee
Wyeth Llc
Medimmune Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38236225&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3020729(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc, Medimmune Limited filed Critical Wyeth Llc
Publication of PL3020729T3 publication Critical patent/PL3020729T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL15184078T 2006-02-21 2007-02-21 Przeciwciała przeciw ludzkiej il-22 i ich zastosowania PL3020729T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77459606P 2006-02-21 2006-02-21
PCT/US2007/004430 WO2007098170A1 (en) 2006-02-21 2007-02-21 Antibodies against human il-22 and uses therefor
EP07751204A EP1991584B1 (en) 2006-02-21 2007-02-21 Antibodies against human il-22 and uses therefor
EP11188458.1A EP2431392B1 (en) 2006-02-21 2007-02-21 Antibodies against human IL-22 and uses therefor
EP15184078.2A EP3020729B1 (en) 2006-02-21 2007-02-21 Antibodies against human il-22 and uses therefor

Publications (1)

Publication Number Publication Date
PL3020729T3 true PL3020729T3 (pl) 2019-12-31

Family

ID=38236225

Family Applications (2)

Application Number Title Priority Date Filing Date
PL15184078T PL3020729T3 (pl) 2006-02-21 2007-02-21 Przeciwciała przeciw ludzkiej il-22 i ich zastosowania
PL07751204T PL1991584T3 (pl) 2006-02-21 2007-02-21 Przeciwciała skierowane przeciwko ludzkiej IL-22 oraz ich zastosowanie

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL07751204T PL1991584T3 (pl) 2006-02-21 2007-02-21 Przeciwciała skierowane przeciwko ludzkiej IL-22 oraz ich zastosowanie

Country Status (31)

Country Link
US (4) US7901684B2 (pl)
EP (3) EP1991584B1 (pl)
JP (1) JP5150516B2 (pl)
KR (2) KR20080113214A (pl)
CN (1) CN101426816B (pl)
AR (1) AR059604A1 (pl)
AT (1) ATE538137T1 (pl)
AU (1) AU2007217751B2 (pl)
BR (1) BRPI0708101B8 (pl)
CA (1) CA2643226C (pl)
CR (1) CR10237A (pl)
DK (2) DK1991584T3 (pl)
EC (1) ECSP088751A (pl)
ES (2) ES2377463T3 (pl)
HN (1) HN2008001292A (pl)
HU (1) HUE044595T2 (pl)
IL (1) IL193605A (pl)
MX (2) MX337778B (pl)
MY (1) MY146664A (pl)
NO (1) NO20083715L (pl)
NZ (1) NZ570878A (pl)
PE (1) PE20080111A1 (pl)
PL (2) PL3020729T3 (pl)
PT (2) PT3020729T (pl)
RU (1) RU2467016C2 (pl)
SA (1) SA07280062B1 (pl)
SG (1) SG172628A1 (pl)
SI (2) SI3020729T1 (pl)
TW (1) TWI417301B (pl)
WO (1) WO2007098170A1 (pl)
ZA (1) ZA200807278B (pl)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2367965C (en) * 1999-04-28 2015-12-01 Kenneth Jacobs Human gil-19/ae289 proteins and polynucleotides encoding same
CN105859886A (zh) 2005-12-02 2016-08-17 健泰科生物技术公司 牵涉与il-22和il-22r结合的抗体的组合物和方法
TWI417301B (zh) * 2006-02-21 2013-12-01 Wyeth Corp 對抗人類介白素-２２（ｉｌ-２２）之抗體及其用途
US20110159011A1 (en) * 2008-08-28 2011-06-30 Wyeth Llc Uses of il-22, il-17, and il-1 family cytokines in autoimmune diseases
WO2011022093A2 (en) 2009-04-13 2011-02-24 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for detecting the presence of an analyte in a sample
AU2010291985B2 (en) 2009-09-14 2016-05-05 The Regents Of The University Of Colorado Modulation of yeast-based immunotherapy products and responses
JP5937019B2 (ja) * 2010-03-12 2016-06-22 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 磁気センサに基づく結合反応速度の定量的な分析
EP2566514A4 (en) * 2010-05-03 2013-11-27 Abbvie Inc METHODS OF INHIBITING FIBROSIS WITH ANTI-PAI-1 ANTIBODIES
CN103382223B (zh) * 2012-04-01 2015-06-10 上海益杰生物技术有限公司 针对表皮生长因子受体隐蔽表位和t细胞抗原的多功能抗体多肽
WO2014015133A1 (en) * 2012-07-19 2014-01-23 National Cheng Kung University Treatment of osteoarthritis using il-20 antagonists
EP2890711B1 (en) * 2012-08-31 2017-01-04 Argen-X Nv Method for producing antibody molecules having inter-species, intra-target cross-reactivity
CA2903587C (en) 2013-03-15 2021-09-28 Genentech, Inc. Il-22 polypeptides and il-22 fc fusion proteins and methods of use
CN105139918B (zh) * 2015-06-26 2017-04-12 哈尔滨工业大学 一种柔板印刷用低银高性能导电浆料及其制备方法
CN105601739B (zh) * 2016-02-22 2019-01-18 王晨辉 一种人源化抗白介素22基因工程抗体及其应用
WO2018039107A1 (en) * 2016-08-22 2018-03-01 Medimmune, Llc Binding molecules specific for notch4 and uses thereof
US20190317098A1 (en) * 2016-11-24 2019-10-17 Huvet Bio, Inc. Composition for diagnosis of diseases
KR102533814B1 (ko) 2016-11-28 2023-05-19 추가이 세이야쿠 가부시키가이샤 리간드 결합 활성을 조정 가능한 리간드 결합 분자
KR20240018673A (ko) 2016-11-28 2024-02-13 추가이 세이야쿠 가부시키가이샤 항원 결합 도메인 및 운반 부분을 포함하는 폴리펩티드
JP7482630B2 (ja) 2017-11-28 2024-05-14 中外製薬株式会社 抗原結合ドメインおよび運搬部分を含むポリペプチド
TWI818934B (zh) 2017-11-28 2023-10-21 日商中外製藥股份有限公司 可調整配體結合活性的配體結合分子
KR102536314B1 (ko) * 2018-05-23 2023-05-25 주식회사 휴벳바이오 질환의 진단용 조성물
CA3102391A1 (en) * 2018-06-05 2019-12-12 Bioatla, Inc. Anti-il-22 antibodies, antibody fragments, their immunoconjugates and uses thereof
EP3863602A1 (en) * 2018-10-11 2021-08-18 Alivio Therapeutics, Inc. Non-injectable hydrogel formulations for smart release
KR102226826B1 (ko) * 2020-08-06 2021-03-11 주식회사 휴벳바이오 버피 코트 시료에 사용하기 위한 췌장암 진단용 조성물
IL303294A (en) 2020-12-07 2023-07-01 UCB Biopharma SRL Antibodies against interleukin-22
AU2021395729A1 (en) 2020-12-07 2023-07-13 UCB Biopharma SRL Multi-specific antibodies and antibody combinations
KR20230165212A (ko) 2021-03-02 2023-12-05 다나-파버 캔서 인스티튜트 인크. 적혈구 장애의 치료 방법
WO2023110942A1 (en) 2021-12-14 2023-06-22 Charité-Universitätsmedizin Berlin Prevention of impaired fracture healing
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

Family Cites Families (93)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
JPS5896026A (ja) 1981-10-30 1983-06-07 Nippon Chemiphar Co Ltd 新規ウロキナ−ゼ誘導体およびその製造法ならびにそれを含有する血栓溶解剤
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4609546A (en) 1982-06-24 1986-09-02 Japan Chemical Research Co., Ltd. Long-acting composition
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
JPS6147500A (ja) 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
EP0206448B1 (en) 1985-06-19 1990-11-14 Ajinomoto Co., Inc. Hemoglobin combined with a poly(alkylene oxide)
US4766106A (en) 1985-06-26 1988-08-23 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
WO1987005330A1 (en) 1986-03-07 1987-09-11 Michel Louis Eugene Bergh Method for enhancing glycoprotein stability
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
DE3883899T3 (de) 1987-03-18 1999-04-22 Sb2, Inc., Danville, Calif. Geänderte antikörper.
US6018026A (en) 1988-01-22 2000-01-25 Zymogenetics, Inc. Biologically active dimerized and multimerized polypeptide fusions
US5750375A (en) 1988-01-22 1998-05-12 Zymogenetics, Inc. Methods of producing secreted receptor analogs and biologically active dimerized polypeptide fusions
DE768377T1 (de) 1988-09-02 1998-01-02 Dyax Corp Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8905669D0 (en) 1989-03-13 1989-04-26 Celltech Ltd Modified antibodies
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
DK0585287T3 (da) 1990-07-10 2000-04-17 Cambridge Antibody Tech Fremgangsmåde til fremstilling af specifikke bindingsparelementer
GB9021679D0 (en) 1990-10-05 1990-11-21 Gorman Scott David Antibody preparation
CA2095633C (en) 1990-12-03 2003-02-04 Lisa J. Garrard Enrichment method for variant proteins with altered binding properties
ES2287206T3 (es) 1991-03-01 2007-12-16 Dyax Corporation Proceso para el desarrollo de mini-proteinas de union.
WO1992018619A1 (en) 1991-04-10 1992-10-29 The Scripps Research Institute Heterodimeric receptor libraries using phagemids
EP0940468A1 (en) 1991-06-14 1999-09-08 Genentech, Inc. Humanized antibody variable domain
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
US5833976A (en) * 1991-08-06 1998-11-10 Schering Corporation Use of interleukin-10 (IL-10) to treat endotoxin- or superantigen-induced toxicity
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
GB9214857D0 (en) 1992-07-13 1992-08-26 Medical Res Council Human nucleic acid fragments and their use
DE69330523D1 (de) 1992-08-21 2001-09-06 Vrije Universiteit Brussel Bru Immunoglobuline ohne leichte ketten
US5789192A (en) 1992-12-10 1998-08-04 Schering Corporation Mammalian receptors for interleukin-10 (IL-10)
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast
ES2162863T3 (es) 1993-04-29 2002-01-16 Unilever Nv Produccion de anticuerpos o fragmentos (funcionalizados) de los mismos derivados de inmunoglobulinas de cadena pesada de camelidae.
WO1994029351A2 (en) 1993-06-16 1994-12-22 Celltech Limited Antibodies
US5674487A (en) * 1994-09-28 1997-10-07 Univ Jefferson Method for treating autoimmune diseases
EP0823941A4 (en) 1995-04-28 2001-09-19 Abgenix Inc HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES
ES2176484T3 (es) 1995-08-18 2002-12-01 Morphosys Ag Bancos de proteinas/(poli)peptidos.
DK0929578T3 (da) 1996-02-09 2003-08-25 Abbott Lab Bermuda Ltd Humane antistoffer, der binder human TNFalfa
US20010006637A1 (en) * 1996-04-19 2001-07-05 Tohru Akahoshi Rheumatoid arthritis remedy containing anti-il-8 antibody as active ingredient
ES2294799T3 (es) 1996-06-27 2008-04-01 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. Moleculas de anticuerpos que interactuan especificamente con el sitio activo o hendidura de una molecula diana.
US6492507B1 (en) * 1996-10-23 2002-12-10 Incyte Genomics, Inc. Polynucleotides encoding human eosinophil-derived basic protein
EP1500329B1 (en) 1996-12-03 2012-03-21 Amgen Fremont Inc. Human antibodies that specifically bind human TNF alpha
ATE319745T1 (de) 1997-05-21 2006-03-15 Biovation Ltd Verfahren zur herstellung von nicht-immunogenen proteinen
WO2002016611A2 (en) 2000-08-24 2002-02-28 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US20030032057A1 (en) * 1997-08-26 2003-02-13 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6551799B2 (en) * 1999-12-07 2003-04-22 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US6350892B1 (en) 1997-09-23 2002-02-26 Bristol-Myers Squibb Company Trifluoromethyl ketone analogs as selective cPLA2 inhibitors
JP4481489B2 (ja) * 1998-01-23 2010-06-16 エフ．ホフマン−ラ ロシュ アーゲー ヒトｉｌ−１２に対する抗体
EP1082433A4 (en) 1998-05-29 2003-01-02 Human Genome Sciences Inc Interleukins 21 and 22
US20010023070A1 (en) * 1998-05-29 2001-09-20 Reinhard Ebner Interleukins-21 and 22
US7081528B2 (en) * 1998-10-26 2006-07-25 Ludwig Institute For Cancer Research Isolated nucleic acid molecules encoding T cell derived inducible factors
AU760224B2 (en) * 1998-10-26 2003-05-08 Wyeth Isolated nucleic acid molecules which encode T cell inducible factors (TIFs), the proteins encoded, and uses thereof
US6274710B1 (en) * 1998-10-26 2001-08-14 Ludwig Institute For Cancer Research Antibodies which specifically bind T Cell inducible factors (TIFs)
AU776910B2 (en) 1998-12-08 2004-09-23 Merck Patent Gesellschaft Mit Beschrankter Haftung Modifying protein immunogenicity
KR20120091477A (ko) 1999-03-25 2012-08-17 애보트 게엠베하 운트 콤파니 카게 사람 ｉｌ-12에 결합하는 사람 항체 및 이의 제조방법
US6939545B2 (en) * 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
US7307161B1 (en) * 1999-04-28 2007-12-11 Genetics Institute, Llc Human Gil-19/AE289 polynucleotides
AU5151100A (en) * 1999-05-19 2000-12-05 Incyte Genomics, Inc. Extracellular signaling molecules
AU5047600A (en) 1999-05-27 2000-12-18 Schering Corporation Mammalian interleukin-10 homologs: il-d110 and il-d210
ATE449109T1 (de) 1999-06-15 2009-12-15 Genentech Inc Sekretierte und transmembran-polypeptide sowie nukleinsäuren zu deren kodierung
AU2253301A (en) * 1999-12-03 2001-06-12 Zymogenetics Inc. Human cytokine receptor
WO2001046422A1 (en) 1999-12-23 2001-06-28 Zymogenetics, Inc. Novel cytokine zcyto18
US20030170823A1 (en) * 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
WO2001055112A1 (en) 2000-01-27 2001-08-02 American Cyanamid Company Method for preparing alpha-sulfonyl hydroxamic acid derivatives
JP2004500086A (ja) * 2000-02-10 2004-01-08 アボット・ラボラトリーズ ヒトインターロイキン１８に結合する抗体とその調整方法および使用方法
US20030012788A1 (en) * 2000-07-27 2003-01-16 Jean-Christophe Renauld Method for influencing kinase pathways with IL-22
ES2349312T3 (es) 2000-07-27 2010-12-29 Wyeth Llc Uso de anticuerpos antagonistas del receptor de il-10 para inhibir la inducción por il-tif/il-21 de proteínas de fase aguda.
US7094570B2 (en) * 2003-03-11 2006-08-22 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which encode a soluble IL-TIF/IL-22 receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
US7829084B2 (en) 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
US20030133939A1 (en) 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
CA2438238A1 (en) 2001-02-23 2002-09-06 Genetics Institute, Llc. Composition comprising il-22 inhibitors and use thereof for treating inflammatory disorders
US7638604B2 (en) * 2001-02-23 2009-12-29 Genetics Institute, Llc Monoclonal antibodies against interleukin-22
US20040058445A1 (en) 2001-04-26 2004-03-25 Ledbetter Jeffrey Alan Activation of tumor-reactive lymphocytes via antibodies or genes recognizing CD3 or 4-1BB
US20020187512A1 (en) 2001-09-10 2002-12-12 Nagem Ronaldo Alves Pinto Crystal structure of human interleukin-22
US7265211B2 (en) * 2002-03-22 2007-09-04 Zymogenetics, Inc. Anti-IL-TIF antibodies and methods of making
ATE518884T1 (de) * 2002-05-01 2011-08-15 Human Genome Sciences Inc Spezifisch an chemokin beta-4 bindende antikörper
US6921538B2 (en) * 2002-05-10 2005-07-26 Allergan, Inc. Therapeutic treatments for neuropsychiatric disorders
CN1839157A (zh) * 2003-06-23 2006-09-27 遗传研究所公司 抗白介素－22抗体及其应用
CA2612746A1 (en) 2005-07-04 2007-01-11 Samsung Electronics Co., Ltd. Position measuring system and method using wireless broadband (wibro) signal
TW200744634A (en) 2006-02-21 2007-12-16 Wyeth Corp Methods of using antibodies against human IL-22
TWI417301B (zh) 2006-02-21 2013-12-01 Wyeth Corp 對抗人類介白素-２２（ｉｌ-２２）之抗體及其用途
US8359965B2 (en) 2007-09-17 2013-01-29 Oxford J Craig Apparatus and method for broad spectrum radiation attenuation

Also Published As

Publication number Publication date
US20070243589A1 (en) 2007-10-18
EP1991584B1 (en) 2011-12-21
CN101426816A (zh) 2009-05-06
AU2007217751A1 (en) 2007-08-30
AR059604A1 (es) 2008-04-16
HK1120813A1 (en) 2009-04-09
ZA200807278B (en) 2009-05-27
ES2738731T3 (es) 2020-01-24
KR101616712B1 (ko) 2016-04-29
SA07280062B1 (ar) 2012-03-13
JP5150516B2 (ja) 2013-02-20
US20110275790A1 (en) 2011-11-10
US7901684B2 (en) 2011-03-08
US8182817B2 (en) 2012-05-22
EP2431392B1 (en) 2015-09-09
HUE044595T2 (hu) 2019-11-28
KR20080113214A (ko) 2008-12-29
US20100184960A1 (en) 2010-07-22
US8187603B2 (en) 2012-05-29
DK3020729T3 (da) 2019-07-29
EP2431392A1 (en) 2012-03-21
US20130005033A1 (en) 2013-01-03
PL1991584T3 (pl) 2012-05-31
CN101426816B (zh) 2012-12-12
US8470993B2 (en) 2013-06-25
PT1991584E (pt) 2012-02-20
EP3020729B1 (en) 2019-06-26
KR20140100589A (ko) 2014-08-14
BRPI0708101B1 (pt) 2020-01-14
DK1991584T3 (da) 2012-04-02
RU2008134137A (ru) 2010-03-27
IL193605A (en) 2015-07-30
ECSP088751A (es) 2008-11-27
ATE538137T1 (de) 2012-01-15
PE20080111A1 (es) 2008-02-20
HN2008001292A (es) 2012-02-13
CR10237A (es) 2008-11-26
CA2643226C (en) 2016-04-12
BRPI0708101A2 (pt) 2011-05-17
BRPI0708101B8 (pt) 2021-05-25
CA2643226A1 (en) 2007-08-30
SG172628A1 (en) 2011-07-28
TWI417301B (zh) 2013-12-01
SI1991584T1 (sl) 2012-05-31
RU2467016C2 (ru) 2012-11-20
IL193605A0 (en) 2011-08-01
JP2009531023A (ja) 2009-09-03
MY146664A (en) 2012-09-14
ES2377463T3 (es) 2012-03-27
MX2008010708A (es) 2008-11-14
MX337778B (es) 2016-03-18
NO20083715L (no) 2008-11-06
TW200801041A (en) 2008-01-01
EP3020729A1 (en) 2016-05-18
PT3020729T (pt) 2019-08-06
EP1991584A1 (en) 2008-11-19
SI3020729T1 (sl) 2019-10-30
NZ570878A (en) 2011-09-30
AU2007217751B2 (en) 2012-08-23
BRPI0708101A8 (pt) 2019-01-22
WO2007098170A1 (en) 2007-08-30

Similar Documents

Publication Publication Date Title
ZA200807278B (en) Antibodies against human IL-22 and uses therefor
IL195658A0 (en) Anti-nkg2a antibodies and uses thereof
ZA200900351B (en) Prlr-specific antibody and uses thereof
EP2097534A4 (en) HUMAN ANTIBODIES BINDING TO CD70 AND USES THEREOF
IL205866A0 (en) Antibodies against human nkg2d and uses thereof
SI2327423T1 (sl) Človeška protitelesa proti človeškemu interlevkinu-22 (IL-22)
IL200012A0 (en) Anti-robo4 antibodies and uses therefor
ZA201102004B (en) Antibodies against human il 17 and uses thereof
IL200610A0 (en) Human monoclonal anti-ip-10 antibodies and uses thereof
IL187375A0 (en) Anti-gm-csf antibodies and uses therefor
IL184024A0 (en) Irta-5 antibodies and their uses
ZA200707339B (en) Human antibodies against rabies and uses thereof
ZA200904657B (en) Human antibodies that bind CD70 and uses thereof
ZA200906516B (en) Novel human anti-R7V antibodies and uses thereof
AP2008004471A0 (en) Anti-Alpha2 Intergin antibodies and their uses
ZA200705716B (en) IRTA-2 antibodies and their uses
ZA200905136B (en) Anti-robo4 antibodies and uses therefor