BR9914777A - Moléculas isoladas de ácido nucléico que codificam os fatores induzìveis por células t (tifs), as proteìnas codificadas e os usos das mesmas - Google Patents

Moléculas isoladas de ácido nucléico que codificam os fatores induzìveis por células t (tifs), as proteìnas codificadas e os usos das mesmas

Info

Publication number
BR9914777A
BR9914777A BR9914777-7A BR9914777A BR9914777A BR 9914777 A BR9914777 A BR 9914777A BR 9914777 A BR9914777 A BR 9914777A BR 9914777 A BR9914777 A BR 9914777A
Authority
BR
Brazil
Prior art keywords
nucleic acid
acid molecules
tifs
cells
isolated nucleic
Prior art date
Application number
BR9914777-7A
Other languages
English (en)
Inventor
Laure Dumoutier
Jamila Louhed
Jean-Christophe Renauld
Original Assignee
Ludwig Inst Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26874873&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9914777(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US09/178,973 external-priority patent/US6274710B1/en
Application filed by Ludwig Inst Cancer Res filed Critical Ludwig Inst Cancer Res
Publication of BR9914777A publication Critical patent/BR9914777A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"MOLéCULAS ISOLADAS DE áCIDO NUCLEìCO QUE CODIFICAM OS FATORES INDUZìVEIS POR CéLULAS T (TIFs), AS PROTEìNAS CODIFICADAS E OS USOS DAS MESMAS" A presente invenção envolve a isolação das moléculas do ácido nucléico, a expressão das quais é regulada para cima, através da interleucina-9. As seq³ências de aminoácidos das proteínas que correspondem às moléculas do ácido nucléico mostram algumas características estruturais de citocinas. Além das moléculas do ácido nucléico e das proteínas, são apresentados os vários usos das moléculas. As moléculas são referidas como os fatores induzíveis por células T.
BR9914777-7A 1998-10-26 1999-10-18 Moléculas isoladas de ácido nucléico que codificam os fatores induzìveis por células t (tifs), as proteìnas codificadas e os usos das mesmas BR9914777A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/178,973 US6274710B1 (en) 1998-10-26 1998-10-26 Antibodies which specifically bind T Cell inducible factors (TIFs)
US09/354,243 US6359117B1 (en) 1998-10-26 1999-07-16 Isolated nucleic acid molecules which encode T cell inducible factors (TIFs), the proteins encoded, and uses therefor
PCT/US1999/024424 WO2000024758A1 (en) 1998-10-26 1999-10-18 ISOLATED NUCLEIC ACID MOLECULES WHICH ENCODE T CELL INDUCIBLE FACTORS (TIFs), THE PROTEINS ENCODED, AND USES THEREOF

Publications (1)

Publication Number Publication Date
BR9914777A true BR9914777A (pt) 2001-07-03

Family

ID=26874873

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9914777-7A BR9914777A (pt) 1998-10-26 1999-10-18 Moléculas isoladas de ácido nucléico que codificam os fatores induzìveis por células t (tifs), as proteìnas codificadas e os usos das mesmas

Country Status (9)

Country Link
US (1) US6331613B1 (pt)
EP (1) EP1131333B1 (pt)
JP (1) JP3769189B2 (pt)
CN (1) CN1238367C (pt)
AU (1) AU760224B2 (pt)
BR (1) BR9914777A (pt)
CA (1) CA2347066C (pt)
HK (1) HK1040401A1 (pt)
WO (1) WO2000024758A1 (pt)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002016611A2 (en) * 2000-08-24 2002-02-28 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US6551799B2 (en) 1999-12-07 2003-04-22 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US7081528B2 (en) * 1998-10-26 2006-07-25 Ludwig Institute For Cancer Research Isolated nucleic acid molecules encoding T cell derived inducible factors
US6274710B1 (en) * 1998-10-26 2001-08-14 Ludwig Institute For Cancer Research Antibodies which specifically bind T Cell inducible factors (TIFs)
AU2003262307B2 (en) * 1999-04-28 2007-03-22 Genetics Institute, Llc Human GIL-19/AE289 proteins and polynucleotides encoding same
US7307161B1 (en) 1999-04-28 2007-12-11 Genetics Institute, Llc Human Gil-19/AE289 polynucleotides
EP2357193B1 (en) * 1999-04-28 2015-11-04 Genetics Institute, LLC Human GIL-19/AE289 proteins and polynucleotides encoding same
US6939545B2 (en) * 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
SI1177312T1 (sl) * 1999-04-28 2008-04-30 Genetics Inst Llc Humani gil-19/ae289 proteini in polinukleotidi, ki omenjene kodirajo
EP1234035B1 (en) 1999-12-03 2010-02-24 ZymoGenetics, Inc. Human cytokine receptor
US7226591B2 (en) 2000-05-22 2007-06-05 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
AU2292601A (en) * 1999-12-23 2001-07-03 Zymogenetics Inc. Novel cytokine zcyto18
US20030170823A1 (en) 1999-12-23 2003-09-11 Presnell Scott R. Novel cytokine ZCYTO18
EP1806404B1 (en) * 2000-07-27 2010-08-18 Wyeth LLC Use of IL-10 receptor beta antagonistic antibodies for inhibiting IL-TIF/IL-21 induction of acute phase proteins
US20030012788A1 (en) * 2000-07-27 2003-01-16 Jean-Christophe Renauld Method for influencing kinase pathways with IL-22
US20030023033A1 (en) * 2001-07-26 2003-01-30 Laure Dumoutier Novel class II cytokine receptors and uses thereof
ATE547525T1 (de) 2000-08-08 2012-03-15 Zymogenetics Inc Lösliche zcyctor 11 cytokinrezeptoren
EP2014298A3 (en) * 2000-08-24 2009-10-07 Genentech, Inc. Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders
US7268223B2 (en) * 2000-09-22 2007-09-11 Wyeth Isolated nucleic acid molecules which encode a soluble IL-TIF receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
US7094570B2 (en) 2003-03-11 2006-08-22 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which encode a soluble IL-TIF/IL-22 receptor or binding protein which binds to IL-TIF/IL-22, and uses thereof
NZ527396A (en) * 2001-02-23 2007-12-21 Genetics Inst Llc Antibodies and fragments thereof for the binding of IL-22 and use therefore for treating inflammatory disorders
US7638604B2 (en) 2001-02-23 2009-12-29 Genetics Institute, Llc Monoclonal antibodies against interleukin-22
WO2002070655A2 (en) 2001-03-02 2002-09-12 Zymogenetics, Inc. Mouse cytokine receptor
US20030099608A1 (en) 2001-03-27 2003-05-29 Presnell Scott R. Human cytokine receptor
DE60228136D1 (de) 2001-04-20 2008-09-18 Zymogenetics Inc Cytokin-proteinfamilie
US7265211B2 (en) 2002-03-22 2007-09-04 Zymogenetics, Inc. Anti-IL-TIF antibodies and methods of making
EP1497415B1 (en) 2002-04-19 2010-12-29 ZymoGenetics, L.L.C. Methods for detection or modulation of the interaction of a cytokine receptor with its ligand
EP1606316A2 (en) 2003-03-24 2005-12-21 ZymoGenetics, Inc. Anti-il-20 antibodies and binding partners and methods of using in inflammation
WO2006047249A1 (en) 2004-10-22 2006-05-04 Zymogenetics, Inc. Anti-il-22ra antibodies and binding partners and methods of using in inflammation
CN100515491C (zh) * 2005-01-04 2009-07-22 健能隆医药技术（上海）有限公司 白介素-22的医药用途
WO2006086396A2 (en) 2005-02-08 2006-08-17 Zymogenetics, Inc. Anti-il-20, anti-il-22 and anti-il-22ra antibodies and binding partners and methods of using in inflammation
AU2006342792A1 (en) 2005-12-02 2007-11-08 Genentech, Inc. Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to IL-22 and IL-22R
TW200744634A (en) 2006-02-21 2007-12-16 Wyeth Corp Methods of using antibodies against human IL-22
TWI417301B (zh) 2006-02-21 2013-12-01 Wyeth Corp 對抗人類介白素-２２（ｉｌ-２２）之抗體及其用途
CN101361968B (zh) 2007-08-06 2011-08-03 健能隆医药技术（上海）有限公司 白介素-22在治疗脂肪肝中的应用
CN102260343A (zh) 2010-05-25 2011-11-30 健能隆医药技术（上海）有限公司 重组人g-csf二聚体在治疗神经损伤疾病中的用途
CN102380091A (zh) 2010-08-31 2012-03-21 健能隆医药技术（上海）有限公司 白介素-22在治疗病毒性肝炎中的应用
EP2737905B1 (en) 2011-07-25 2019-09-11 Generon (Shanghai) Corporation Ltd. Use of g-csf dimer in preparation of medicament for treatment of neurodegenerative diseases
CN103182072B (zh) 2011-12-27 2017-05-03 健能隆医药技术（上海）有限公司 白介素‑22在治疗和预防神经损伤疾病或神经退行性疾病中的用途
TR201809571T4 (tr) 2013-03-15 2018-07-23 Hoffmann La Roche Ll-22 polipeptidleri ile ıl-22 fc füzyon proteinleri ve kullanım yöntemleri.
CN104623637A (zh) 2013-11-07 2015-05-20 健能隆医药技术（上海）有限公司 Il-22二聚体在制备静脉注射药物中的应用
JP6472448B2 (ja) * 2014-07-31 2019-02-20 株式会社トランスジェニック 炎症レポーターシステム
CA2982657A1 (en) * 2015-04-17 2016-10-20 Elsalys Biotech Anti-tyro3 antibodies and uses thereof
WO2017181143A1 (en) 2016-04-15 2017-10-19 Generon (Shanghai) Corporation, Ltd. Use of il-22 in treating necrotizing enterocolitis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5814517A (en) * 1994-04-14 1998-09-29 Ligand Pharmaceuticals, Inc. DNA spacer regulatory elements responsive to cytokines and methods for their use
ZA967182B (en) * 1995-08-24 1998-05-25 Magainin Pharma Asthma associated factors as targets for treating atopic allergies including asthma and related disorders.
EP2357193B1 (en) 1999-04-28 2015-11-04 Genetics Institute, LLC Human GIL-19/AE289 proteins and polynucleotides encoding same
EP2909724B1 (en) 2012-10-19 2019-11-27 Hewlett-Packard Enterprise Development LP Asyncrhonous consistent snapshots in persistent memory stores
DE102012220050A1 (de) 2012-11-02 2014-05-08 Osram Opto Semiconductors Gmbh Organisches optoelektronisches Bauelement und Verfahren zum Betrieb des organischen optoelektronischen Bauelements

Also Published As

Publication number Publication date
HK1040401A1 (en) 2002-06-07
EP1131333B1 (en) 2010-06-02
JP3769189B2 (ja) 2006-04-19
AU6520699A (en) 2000-05-15
EP1131333A4 (en) 2005-03-02
EP1131333A1 (en) 2001-09-12
AU760224B2 (en) 2003-05-08
US6331613B1 (en) 2001-12-18
CA2347066A1 (en) 2000-05-04
CA2347066C (en) 2011-05-03
CN1238367C (zh) 2006-01-25
JP2002528066A (ja) 2002-09-03
CN1332748A (zh) 2002-01-23
WO2000024758A1 (en) 2000-05-04

Similar Documents

Publication Publication Date Title
BR9914777A (pt) Moléculas isoladas de ácido nucléico que codificam os fatores induzìveis por células t (tifs), as proteìnas codificadas e os usos das mesmas
ES2153037T3 (es) Lacasas purificadas de scytalidium y acidos nucleicos que las codifican.
ATE469911T1 (de) Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung
AR030236A1 (es) Moléculas similares a il-17 y usos de las mismas
PT765394E (pt) Lacases myceliophthora purificadas e acidos nucleicos que as codificam
ES2054878T3 (es) Expresion de la proapolipoproteina a-i humana.
ATE319818T1 (de) Polypeptide mit aminopeptidaseaktivität und für diese kodierende nukleinsäuren
DE69841110D1 (de) Verlängerte cdns, die für sekretierte proteine kodieren
BR9816013A (pt) Proteìna de ligação de interleucina-18
DE69930955D1 (de) Polypeptide mit lysophospholipaseaktivität und nukleinesäuren die sie kodieren
AR003125A1 (es) Antigenos bacterianos para el diagnostico de infecciones con helicobacter pylori, una molecula de adn que lo codifica, un vector, una celula huesped,procedimiento para producir el polipeptido, composiciones para vacunas adecuadas para uso terapeutico y profilactico, el uso del polipeptido en la
DE69617440D1 (de) Isolierte nukleinsäuremoleküle, peptide die mit hla-a2 moleküle (mhc) komplexe bilden, sowie deren verwendungen
DE69942861D1 (de) Ldcam genannte moleküle
DE60043428D1 (de) POLYPEPTIDE MIT VERZWEIGUNGSENZYM-AKTIVITäT UND FüR DIESE KODIERENDE NUKLEINSäUREN
AR023482A1 (es) Acidos nucleicos que codifican polipeptidos quimericos cd40/cd4ol, metodos para su produccion y usos de los mismos
AR030554A1 (es) Moleculas similares a receptores il-17 y usos de las mismas
AR013529A1 (es) Rantes amino-terminalmente truncado, moleculas de adn, vector de expresion, celula huesped, proceso recombinante para prepararlo, su uso para preparar un medicamento y composicion farmaceutica que lo comprende.
AU7303301A (en) Isolated nucleic acid molecules which encode t cell inducible factors, or interleukin-21, the proteins encoded, and uses thereof
ES2123269T3 (es) Receptores del factor 2 de liberacion de corticotropina.
PT84089B (pt) Sequencias de adn codificando para proteinas possuindo a actividade biologica dos inibidores de husi-tipo i, processos biotecnologicos para a preparacao das referidas proteinas e de composicoes farmaceuticas contendo as referidas proteinas
AR002742A1 (es) Proteina reguladora del tipo adiposo, procedimiento para producir dicha proteina, formulaciones farmaceuticas que la incluyen, molecula de adn aisladaque codifica dicha proteina, vector y celulas recombinantes que comprenden dicho adn
BR9902019A (pt) Moléculas de polinucleotìdios que codificam proteìnas de neospora.
BR9708005A (pt) C3 convertase resistente à regulação para baixo
ATE162853T1 (de) Menschlicher rekombinanter plazentaler ribonuklease-inhibitor und verfahren zur herstellung
BR0107655A (pt) Polinucleotìdeo isolado, vetor de expressão recombinante, polipeptìdeo, célula, método para produzir o polipeptìdeo, e, composição farmacêutica

Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007.