CN105601739B - 一种人源化抗白介素22基因工程抗体及其应用 - Google Patents
一种人源化抗白介素22基因工程抗体及其应用 Download PDFInfo
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- CN105601739B CN105601739B CN201610095313.9A CN201610095313A CN105601739B CN 105601739 B CN105601739 B CN 105601739B CN 201610095313 A CN201610095313 A CN 201610095313A CN 105601739 B CN105601739 B CN 105601739B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- Organic Chemistry (AREA)
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- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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Abstract
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201610095313.9A CN105601739B (zh) | 2016-02-22 | 2016-02-22 | 一种人源化抗白介素22基因工程抗体及其应用 |
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CN201610095313.9A CN105601739B (zh) | 2016-02-22 | 2016-02-22 | 一种人源化抗白介素22基因工程抗体及其应用 |
Publications (2)
Publication Number | Publication Date |
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CN105601739A CN105601739A (zh) | 2016-05-25 |
CN105601739B true CN105601739B (zh) | 2019-01-18 |
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CN201610095313.9A Active CN105601739B (zh) | 2016-02-22 | 2016-02-22 | 一种人源化抗白介素22基因工程抗体及其应用 |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201612337D0 (en) * | 2016-07-15 | 2016-08-31 | Argen-X N V | Ant-il-22r antibodies |
CN111218425B (zh) * | 2019-01-17 | 2022-02-08 | 百奥赛图(北京)医药科技股份有限公司 | 人源化转基因动物 |
CN110151794A (zh) * | 2019-06-03 | 2019-08-23 | 山东大学齐鲁医院 | 脆弱拟杆菌ych46在治疗或辅助治疗自身免疫性疾病中的应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101426816A (zh) * | 2006-02-21 | 2009-05-06 | 惠氏公司 | 抗人白介素22的抗体及其用途 |
EP1606317B1 (en) * | 2003-03-24 | 2010-07-28 | ZymoGenetics, Inc. | Anti-il-22ra antibodies and binding partners and methods of using in inflammation |
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2016
- 2016-02-22 CN CN201610095313.9A patent/CN105601739B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1606317B1 (en) * | 2003-03-24 | 2010-07-28 | ZymoGenetics, Inc. | Anti-il-22ra antibodies and binding partners and methods of using in inflammation |
CN101426816A (zh) * | 2006-02-21 | 2009-05-06 | 惠氏公司 | 抗人白介素22的抗体及其用途 |
Non-Patent Citations (2)
Title |
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IL-22 is required for Th17 cell–mediated pathology in a mouse model of psoriasis-like skin inflammation;Hak-Ling Ma,et al.;《The Journal of Clinical Investigation》;20080228;第118卷(第2期);第597–607页 |
寻常型银屑病患者外周血中Th22细胞及血清中IL-22的表达;简瑜;《中国优秀硕士学位论文全文数据库 医药卫生科技辑》;20121215(第12期);第E075-2页 |
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CN105601739A (zh) | 2016-05-25 |
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Effective date of registration: 20191204 Address after: 430075 room B111, floor 2, building B6, Wuhan National Biological Industry (Jiufeng innovation) base, No. 666, Gaoxin Avenue, Donghu New Technology Development Zone, Wuhan City, Hubei Province Patentee after: WUHAN YUANGU BIOTECHNOLOGY CO.,LTD. Address before: 430075, B5 building, building 666, high tech Avenue, East Lake Development Zone, Wuhan, Hubei, Wuhan, China, 6 floors Co-patentee before: WUHAN ANDIJINGSAI BIOTECHNOLOGY Co.,Ltd. Patentee before: Wang Chenhui |
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Denomination of invention: A humanized anti interleukin-22 genetically engineered antibody and its application Effective date of registration: 20230410 Granted publication date: 20190118 Pledgee: Bank of China Limited by Share Ltd. Wuhan Wuchang branch Pledgor: WUHAN YUANGU BIOTECHNOLOGY CO.,LTD. Registration number: Y2023980037582 |