PL2470191T3 - Sposoby i kompozycje do profilaktyki lub leczenia stanów okulistycznych - Google Patents

Sposoby i kompozycje do profilaktyki lub leczenia stanów okulistycznych

Info

Publication number
PL2470191T3
PL2470191T3 PL10812524T PL10812524T PL2470191T3 PL 2470191 T3 PL2470191 T3 PL 2470191T3 PL 10812524 T PL10812524 T PL 10812524T PL 10812524 T PL10812524 T PL 10812524T PL 2470191 T3 PL2470191 T3 PL 2470191T3
Authority
PL
Poland
Prior art keywords
compositions
treating
preventing
methods
ophthalmic condition
Prior art date
Application number
PL10812524T
Other languages
English (en)
Inventor
Liping Liu
Shibo Tang
Xiaoling Liang
Original Assignee
Stealth Peptides Int Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stealth Peptides Int Inc filed Critical Stealth Peptides Int Inc
Publication of PL2470191T3 publication Critical patent/PL2470191T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0815Tripeptides with the first amino acid being basic
    • C07K5/0817Tripeptides with the first amino acid being basic the first amino acid being Arg
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL10812524T 2009-08-24 2010-08-23 Sposoby i kompozycje do profilaktyki lub leczenia stanów okulistycznych PL2470191T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US23644009P 2009-08-24 2009-08-24
US23774509P 2009-08-28 2009-08-28
US34847010P 2010-05-26 2010-05-26
EP10812524.6A EP2470191B1 (en) 2009-08-24 2010-08-23 Methods and compositions for preventing or treating ophthalmic conditions
PCT/US2010/046338 WO2011025734A1 (en) 2009-08-24 2010-08-23 Methods and compositions for preventing or treating ophthalmic conditions

Publications (1)

Publication Number Publication Date
PL2470191T3 true PL2470191T3 (pl) 2014-09-30

Family

ID=43628336

Family Applications (2)

Application Number Title Priority Date Filing Date
PL10812524T PL2470191T3 (pl) 2009-08-24 2010-08-23 Sposoby i kompozycje do profilaktyki lub leczenia stanów okulistycznych
PL20156769.0T PL3708178T3 (pl) 2009-08-24 2010-08-23 Peptyd do stosowania w zapobieganiu lub leczeniu zwyrodnienia plamki żółtej

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL20156769.0T PL3708178T3 (pl) 2009-08-24 2010-08-23 Peptyd do stosowania w zapobieganiu lub leczeniu zwyrodnienia plamki żółtej

Country Status (17)

Country Link
US (8) US8470784B2 (pl)
EP (18) EP4302829B1 (pl)
JP (8) JP6120399B2 (pl)
CN (3) CN102625709A (pl)
CA (1) CA2772094C (pl)
DK (2) DK2470191T3 (pl)
ES (3) ES2487633T3 (pl)
FI (1) FI3708178T3 (pl)
HK (4) HK1204958A1 (pl)
HR (1) HRP20231277T1 (pl)
HU (1) HUE064800T2 (pl)
LT (1) LT3708178T (pl)
PL (2) PL2470191T3 (pl)
PT (2) PT3708178T (pl)
SI (2) SI2470191T1 (pl)
SM (1) SMT202300433T1 (pl)
WO (1) WO2011025734A1 (pl)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120084680A1 (en) 2010-10-01 2012-04-05 Imerj LLC Gesture capture for manipulation of presentations on one or more device displays
EP4541320A3 (en) 2008-09-29 2025-07-09 Edwards Lifesciences CardiAQ LLC Heart valve
CA2739275C (en) 2008-10-01 2017-01-17 Impala, Inc. Delivery system for vascular implant
JP2012523894A (ja) 2009-04-15 2012-10-11 カルディアック バルブ テクノロジーズ,インコーポレーテッド 血管インプラント及びその配設システム
EP4302829B1 (en) * 2009-08-24 2025-05-21 Stealth BioTherapeutics Inc. Peptide for use in preventing or treating macular degeneration
EP3375449A1 (en) 2010-03-15 2018-09-19 Stealth Peptides International, Inc. Combination therapies using cyclosporine and aromatic cationic peptides
EP2563359A1 (en) * 2010-04-30 2013-03-06 Allergan, Inc. Novel treatment for age related macular degeneration and ocular ischemic disease associated with complement activation by targeting 5-lipoxygenase
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
US10272040B2 (en) 2010-08-12 2019-04-30 Nanyang Technological University Liposomal formulation for ocular drug delivery
EP3488941A1 (en) * 2011-03-24 2019-05-29 Cornell University Aromatic-cationic peptides and uses of same
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
CN102327600A (zh) * 2011-09-14 2012-01-25 中国人民解放军军事医学科学院放射与辐射医学研究所 用于预防和治疗辐射损伤的rx31肽
US9182935B2 (en) 2011-09-27 2015-11-10 Z124 Secondary single screen mode activation through menu option
EP3466439A1 (en) * 2011-12-09 2019-04-10 Stealth Peptides International, Inc. Aromatic-cationic peptides and uses of same
EP3281634A1 (en) * 2012-02-22 2018-02-14 Stealth Peptides International, Inc. Method and compositions for preventing or treating ophthalmic conditions
WO2013149172A1 (en) * 2012-03-30 2013-10-03 Stealth Peptides International, Inc. Methods and compositions for the prevention and treatment neuropathy
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
EP3485897A1 (en) 2012-08-02 2019-05-22 Stealth Peptides International, Inc. D-arg-2'6'-dmt-lys-phe-nh2 for decreasing statin side effects
CA2888899C (en) 2012-10-24 2023-02-21 Japan Innovative Therapeutics, Inc. Use of tryptase inhibitors in the treatment retinopathy of prematurity
US9265458B2 (en) 2012-12-04 2016-02-23 Sync-Think, Inc. Application of smooth pursuit cognitive testing paradigms to clinical drug development
HUE046924T2 (hu) 2013-03-01 2020-03-30 Stealth Biotherapeutics Corp Módszerek és készítmények Barth szindróma megelõzésében vagy kezelésében történõ alkalmazásra
CA2916884C (en) * 2013-03-01 2021-02-09 Stealth Biotherapeutics Corp Methods for the treatment of mitochondrial disease
US9380976B2 (en) 2013-03-11 2016-07-05 Sync-Think, Inc. Optical neuroinformatics
US10583002B2 (en) 2013-03-11 2020-03-10 Neovasc Tiara Inc. Prosthetic valve with anti-pivoting mechanism
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US10047395B2 (en) 2013-06-26 2018-08-14 Stealth Biotherapeutics Corp Methods and compositions for detecting and diagnosing diseases and conditions
US20160193278A1 (en) * 2013-08-01 2016-07-07 Stealth Biotherapeutics Corp Methods and compositions for preventing or treating leber's hereditary optic neuropathy
WO2015023680A1 (en) * 2013-08-12 2015-02-19 Stealth Peptides International, Inc. Combination therapy for the treatment of ischemia-reperfusion injury
AU2014339890A1 (en) * 2013-10-25 2016-06-02 Children's Medical Center Corporation Methods of treating or preventing vascular diseases of the retina
CA2932408A1 (en) * 2013-12-02 2015-06-11 Stealth Biotherapeutics Corp Compositions and methods for treating vitiligo
US20160317606A1 (en) * 2014-01-06 2016-11-03 Stealth Bio Therapeutics Corp Methods and compositions for preventing or treating dominant optic atrophy
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery
CA2945149A1 (en) 2014-04-10 2015-10-15 Lankenau Institute For Medical Research Methods and compositions for the treatment of ocular diseases and disorders
WO2015183988A1 (en) * 2014-05-28 2015-12-03 Stealth Peptides International, Inc. Therapeutic compositions including therapeutic small molecules and uses thereof
JP2017538728A (ja) * 2014-12-19 2017-12-28 ケミン、インダストリーズ、インコーポレーテッドKemin Industries, Inc. イオントフォレシスを用いた生物活性分子の眼内送達
ES2903397T3 (es) 2015-12-30 2022-04-01 Marshall Univ Research Corporation Composiciones y métodos para tratar la retinopatía
CA3017359A1 (en) 2016-03-11 2017-09-14 Scott M. Duncan Crystalline salt forms
US10870678B2 (en) 2016-04-11 2020-12-22 Arcuate Therapeutics, Inc. Chiral peptides
WO2017177262A1 (en) 2016-04-11 2017-10-19 University Of Canberra Ophthalmic compositions comprising levodopa, an antioxidant and an aqueous carrier
US11034724B2 (en) 2017-04-05 2021-06-15 Stealth Biotherapeutics Corp. Crystalline salt forms of Boc-D-Arg-DMT-Lys-(Boc)-Phe-NH2
US20180318319A1 (en) 2017-05-04 2018-11-08 Ocular Science, Inc. Compositions and Methods for Treating Eyes and Methods of Preparation
CA3081553C (en) 2017-11-17 2022-11-15 Cellix Bio Private Limited Compositions and methods for the treatment of eye disorders
US10676506B2 (en) 2018-01-26 2020-06-09 Stealth Biotherapeutics Corp. Crystalline bis- and tris-hydrochloride salt of elamipretide
PL424452A1 (pl) * 2018-01-31 2019-08-12 Forty-Four Pharmaceuticals Spółka Z Ograniczoną Odpowiedzialnością Inhibitory obojętnej endopeptydazy (NEP) i ludzkiej rozpuszczalnej endopeptydazy (hSEP) do profilaktyki i leczenia chorób oczu
EP3787749A4 (en) * 2018-05-03 2022-01-26 Alimera Sciences, Inc. METHODS OF TREATMENT OF RETINAL DISEASES
WO2020018455A1 (en) * 2018-07-16 2020-01-23 Stealth Biotherapeutics Corp Compositions and methods for the treatment of traumatic optic neuropathy
EP3852608A4 (en) * 2018-09-21 2022-09-28 Aufbau Medical Innovations Limited COMPOSITIONS AND METHODS FOR TREATING GLAUCOMA
WO2020144546A1 (en) * 2019-01-12 2020-07-16 Cellix Bio Private Limited Combination of selective alpha-adrenergic receptor agonist or an anticholinergic agent and lipoic acid and uses thereof
JP2020174859A (ja) * 2019-04-17 2020-10-29 学校法人日本医科大学 網膜剥離が生じるリスクが低い網膜変性症(rd)モデルマウスを取得する方法
WO2020214990A1 (en) * 2019-04-17 2020-10-22 Ascidian Therapeutics, Inc. Abca4 cell line and methods of use
US11071724B2 (en) 2019-05-17 2021-07-27 Ocular Science, Inc. Compositions and methods for treating presbyopia
WO2020240558A1 (en) * 2019-05-28 2020-12-03 Elgan Pharma Ltd Compositions and methods for treating retinopathy
CA3173100A1 (en) * 2020-03-25 2021-09-30 John T. G. PENA Processes and agents for glaucoma
CN116744904A (zh) * 2020-12-24 2023-09-12 参天制药株式会社 含有依匹斯汀或其盐和硫系抗氧化剂的经皮施予用医药组合物
AU2022370358A1 (en) * 2021-10-20 2024-05-02 Stealth Biotherapeutics Inc. Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions
WO2023069255A1 (en) * 2021-10-20 2023-04-27 Stealth Biotherapeutics Inc. Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions
US20230226105A1 (en) * 2021-11-10 2023-07-20 Reverspah Llc Methods and compositions for treating cancer
CN114099678A (zh) * 2021-11-23 2022-03-01 浙江大学 基于Keap1-Nrf2信号通路的晶状体损伤抑制剂
KR102662922B1 (ko) * 2022-05-31 2024-05-03 주식회사 세네릭스 신규의 d-아미노산 유도체 및 이를 포함하는 약학 조성물

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US5602100A (en) * 1988-06-30 1997-02-11 Astra Ab Dermorphin analogs having pharmacological activity
ES2085865T3 (es) * 1988-06-30 1996-06-16 Astra Ab Analogos de dermorfina, sus metodos de preparacion, composiciones farmaceuticas, y metodos de tratamiento terapeutico que los emplean.
US5652122A (en) * 1989-12-21 1997-07-29 Frankel; Alan Nucleic acids encoding and methods of making tat-derived transport polypeptides
US5858784A (en) 1991-12-17 1999-01-12 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol- and liposome-based delivery
US5716644A (en) 1992-06-11 1998-02-10 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
US5674534A (en) 1992-06-11 1997-10-07 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
DE69630918T2 (de) * 1995-06-09 2004-10-28 Hisamitsu Pharmaceutical Co., Inc., Tosu Matrix für Iontophorese
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US5885958A (en) * 1997-03-25 1999-03-23 Administrators Of The Tulane Educational Fund Mu-opiate receptor peptides
US5989463A (en) 1997-09-24 1999-11-23 Alkermes Controlled Therapeutics, Inc. Methods for fabricating polymer-based controlled release devices
AU1818299A (en) * 1997-12-10 1999-06-28 Washington University Anti-pathogen system and methods of use thereof
US6268398B1 (en) * 1998-04-24 2001-07-31 Mitokor Compounds and methods for treating mitochondria-associated diseases
US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
SE9900961D0 (sv) * 1999-03-16 1999-03-16 Astra Ab Novel compounds
CA2386239A1 (en) * 1999-10-04 2001-04-12 University Of Medicine And Dentistry Of New Jersey Methods for identifying rna binding compounds
US6759520B1 (en) * 1999-10-28 2004-07-06 The New England Medical Center Hospitals, Inc. Chimeric analgesic peptides
US20050192215A1 (en) * 2000-01-21 2005-09-01 Malabika Ghosh Methods and materials relating to novel polypeptides and polynucleotides
JP2001270832A (ja) * 2000-03-27 2001-10-02 Ito En Ltd 網膜障害予防剤
AU2001277908A1 (en) * 2000-07-18 2002-01-30 Cornell Research Foundation Inc. Medicinal uses of mu-opioid receptor agonists
US6900178B2 (en) * 2000-09-12 2005-05-31 University Of Kentucky Research Foundation Protection against ischemia and reperfusion injury
US20070015146A1 (en) * 2001-05-22 2007-01-18 Gene Logic, Inc. Molecular nephrotoxicology modeling
US7259180B2 (en) * 2002-08-14 2007-08-21 University Of Georgia Research Foundation, Inc. Methods and compositions for treatment of macular and retinal disease
US7354574B2 (en) * 2002-11-07 2008-04-08 Advanced Ocular Systems Limited Treatment of ocular disease
US20060172972A1 (en) 2002-12-20 2006-08-03 Chakshu Research Inc Formulation and method for administration of ophthalmologically active agents
PT1599216E (pt) * 2003-02-04 2013-12-17 Cornell Res Foundation Inc Métodos de prevenção da transição de permeabilidade mitocondrial
JP2004323486A (ja) * 2003-04-30 2004-11-18 National Institute Of Advanced Industrial & Technology 網膜及び/又はブドウ膜疾患の予防乃至治療用点眼薬
ZA200509229B (en) * 2003-05-01 2007-03-28 Cornell Res Foundation Inc Method and carrier complexes for delivering molecules to cells
WO2005032481A2 (en) * 2003-09-30 2005-04-14 Scios Inc. Quinazoline derivatives as medicaments
NZ549393A (en) * 2004-01-23 2009-07-31 Cornell Res Foundation Inc Methods for reducing oxidative damage
US20050245497A1 (en) 2004-04-08 2005-11-03 Penfold Philip L Treatment of ophthalmic conditions
US20050272101A1 (en) * 2004-06-07 2005-12-08 Prasad Devarajan Method for the early detection of renal injury
JP4760111B2 (ja) 2005-04-26 2011-08-31 株式会社セガ 映像オブジェクト表現用データ構造生成プログラム、映像オブジェクト表現用データ構造生成方法、映像ソフト開発装置、映像処理プログラム、映像処理方法、映像処理装置、映像オブジェクト表現用データ構造、および、記録媒体
US8088773B2 (en) 2005-05-12 2012-01-03 The Texas A&M University System Therapeutic compositions and methods
JP2007043629A (ja) * 2005-06-30 2007-02-15 Sony Corp グラフィック・ユーザ・インタフェース装置と操作入力処理方法及び双方向コミュニケーション装置
AU2006270035A1 (en) 2005-07-15 2007-01-25 Chakshu Research Inc. Formulation and method for administration of ophthalmologically active agents
KR20150013353A (ko) * 2005-09-16 2015-02-04 코넬 리서치 화운데이션,인크. Cd36 발현을 감소시키는 방법
EP1932534A1 (en) 2005-10-05 2008-06-18 Aqumen Biopharmaceuticals K.K. Method of inhibiting angiogenesis by using ephrin b2
US20070259377A1 (en) * 2005-10-11 2007-11-08 Mickey Urdea Diabetes-associated markers and methods of use thereof
TW200744627A (en) 2006-02-21 2007-12-16 Pfizer Prod Inc Methods for the treatment of macular degeneration and related eye conditions
BRPI0709977A2 (pt) * 2006-04-14 2011-08-02 Novartis Ag uso de anticorpos de il-1 para o tratamento de distúrbios oftálmicos
US20080027082A1 (en) * 2006-06-19 2008-01-31 Berthold Hocher Use of adenosine a1 antagonists in radiocontrast media induced nephropathy
DE102006042329B4 (de) * 2006-09-01 2008-08-21 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zum selektiven plasmachemischen Trockenätzen von auf Oberflächen von Silicium-Wafern ausgebildetem Phosphorsilikatglas
EP2104509A4 (en) 2006-12-11 2010-03-24 Univ Utah Res Found COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL ANGIOGENESIS AND VASPERMEABILITY
JP2008195655A (ja) * 2007-02-14 2008-08-28 Kitasato Institute 糖尿病白内障の治療剤
JP2008247898A (ja) * 2007-03-08 2008-10-16 Santen Pharmaceut Co Ltd トリテルペノイドを有効成分として含有する酸化ストレスが関連する眼疾患の予防又は治療剤
ES2370751T3 (es) * 2007-05-25 2011-12-22 Santen Pharmaceutical Co., Ltd Agente profiláctico o terapéutico para la degeneración macular asociada a la edad.
EP2712620A1 (en) * 2008-02-07 2014-04-02 Cornell University Methods for Preventing or Treating Insulin Resistance
WO2009108695A2 (en) * 2008-02-26 2009-09-03 Cornell University Methods for prevention and treatment of acute renal injury
CN102573881A (zh) 2009-03-20 2012-07-11 通用医疗公司以马萨诸塞州通用医疗公司名义经营 预防和治疗烧伤损伤和继发性并发症的方法
FR2945540B1 (fr) 2009-05-15 2012-06-08 Rhodia Operations Procede de preparation de mousse polyamide et mousse susceptible d'etre obtenue par ce procede
JP5909182B2 (ja) 2009-08-12 2016-04-26 コーネル ユニヴァーシティー 代謝性症候群を予防し又は治療するための方法
EP4302829B1 (en) * 2009-08-24 2025-05-21 Stealth BioTherapeutics Inc. Peptide for use in preventing or treating macular degeneration
EP2528934A4 (en) * 2010-01-25 2013-08-21 Univ Cornell AROMATIC-CATIONIC PEPTIDES AND USES THEREOF
US20130040901A1 (en) * 2010-02-26 2013-02-14 University Of Florida Research Foundation Inc. Mitochondrial-targeted antioxidants protect against mechanical ventilation-induced diaphragm dysfunction and skeletal muscle atrophy
EP2566880A4 (en) 2010-05-03 2014-10-08 Stealth Peptides Int Inc AROMATIC-CATIONIC PEPTIDES AND USES THEREOF
HK1197028A1 (en) 2011-06-14 2015-01-02 Stealth Peptides International, Inc. Aromatic-cationic peptides and uses of same
CA2916492A1 (en) * 2013-06-27 2014-12-31 Stealth Biotherapeutics Corp Peptide therapeutics and methods for using same
US20160199437A1 (en) * 2015-01-08 2016-07-14 D. Travis Wilson Therapeutic compositions including iron chelators and uses thereof
US20160228491A1 (en) * 2015-02-09 2016-08-11 Stealth Biotherapeutics Corp Therapeutic compositions including phenazine-3-one and phenothiazine-3-one derivatives and uses thereof

Also Published As

Publication number Publication date
JP2018162329A (ja) 2018-10-18
EP3485896A1 (en) 2019-05-22
CA2772094A1 (en) 2011-03-03
JP2017141306A (ja) 2017-08-17
SMT202300433T1 (it) 2024-01-10
US20210154259A1 (en) 2021-05-27
HK1204958A1 (en) 2015-12-11
EP4302829A3 (en) 2024-03-27
US20160058825A1 (en) 2016-03-03
US20200061147A1 (en) 2020-02-27
CN105056206A (zh) 2015-11-18
EP2962695A1 (en) 2016-01-06
ES2964555T3 (es) 2024-04-08
HK1217900A1 (en) 2017-01-27
SI2470191T1 (sl) 2014-08-29
EP3150215A1 (en) 2017-04-05
EP3175862A1 (en) 2017-06-07
ES2487633T3 (es) 2014-08-22
EP2470191B1 (en) 2014-05-07
EP3524256A1 (en) 2019-08-14
EP2957291A1 (en) 2015-12-23
JP2023179733A (ja) 2023-12-19
EP3708178A1 (en) 2020-09-16
US20230346874A1 (en) 2023-11-02
EP3494983A1 (en) 2019-06-12
HRP20231277T1 (hr) 2024-02-02
HK1206258A1 (en) 2016-01-08
EP2813235A1 (en) 2014-12-17
EP3124036A1 (en) 2017-02-01
EP4302829B1 (en) 2025-05-21
DK3708178T3 (da) 2023-11-13
EP3338788A1 (en) 2018-06-27
EP4596049A3 (en) 2025-08-13
PL3708178T3 (pl) 2024-05-13
EP4596049A2 (en) 2025-08-06
HK1247821A1 (zh) 2018-10-05
US20230381264A1 (en) 2023-11-30
JP2013502460A (ja) 2013-01-24
EP3292868A1 (en) 2018-03-14
WO2011025734A1 (en) 2011-03-03
JP2022001609A (ja) 2022-01-06
HUE064800T2 (hu) 2024-04-28
JP2025181975A (ja) 2025-12-11
JP6332757B2 (ja) 2018-05-30
EP2470191A4 (en) 2013-04-17
LT3708178T (lt) 2023-12-27
JP2020128431A (ja) 2020-08-27
US9023807B2 (en) 2015-05-05
US20140044689A1 (en) 2014-02-13
PT3708178T (pt) 2023-11-16
JP7642965B2 (ja) 2025-03-11
CA2772094C (en) 2018-04-03
EP2826487A1 (en) 2015-01-21
US11612633B2 (en) 2023-03-28
EP2990049A1 (en) 2016-03-02
FI3708178T3 (fi) 2023-11-09
US8470784B2 (en) 2013-06-25
JP2016026188A (ja) 2016-02-12
CN107412722A (zh) 2017-12-01
EP2470191A1 (en) 2012-07-04
SI3708178T1 (sl) 2024-01-31
JP6120399B2 (ja) 2017-04-26
EP3708178B1 (en) 2023-10-04
DK2470191T3 (da) 2014-07-07
HK1172833A1 (en) 2013-05-03
PT2470191E (pt) 2014-06-12
US9549963B2 (en) 2017-01-24
US11944662B2 (en) 2024-04-02
US20170326197A1 (en) 2017-11-16
CN102625709A (zh) 2012-08-01
EP4302829A2 (en) 2024-01-10
EP3318264A1 (en) 2018-05-09
ES3036317T3 (en) 2025-09-17
JP6381737B2 (ja) 2018-08-29
US20110177047A1 (en) 2011-07-21
US10188692B2 (en) 2019-01-29

Similar Documents

Publication Publication Date Title
PL2470191T3 (pl) Sposoby i kompozycje do profilaktyki lub leczenia stanów okulistycznych
EP2817018A4 (en) METHODS AND COMPOSITIONS FOR PREVENTING OR TREATING OPHTHALMIC CONDITIONS
EP2608778A4 (en) COMPOSITIONS AND METHODS FOR TREATING BONE ANOMALIES
BR112012004979A2 (pt) composições para o tratamento de semente e métodos
EP2579816A4 (en) Implant components and methods
DK2419732T3 (da) Prionfrie nanopartikelsammensætninger og fremgangsmåder
IL202015A0 (en) Methods and compositions for treating skin conditions
BRPI1007477A2 (pt) método, e, composição de tratamento de poço
EP2655334A4 (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF DISEASES
EP2496084A4 (en) COMPOSITIONS AND METHODS FOR TREATING COLITIS
IL215932A0 (en) Compositions and methods for treating burns
BR112013012485A2 (pt) método de tratamento com inibidor braf
EP2429584A4 (en) TREATMENT PROCEDURE AND COMPOSITIONS
BRPI1011325A2 (pt) composições e métodos para o tratamento de inflamação
EP2635282A4 (en) COMPOSITIONS AND METHOD FOR THE TREATMENT OF MYELOFIBROSIS
BRPI1007929A2 (pt) "métodos e composições para o tratamento de neovascularização".
IL210097A0 (en) Compositions and methods for treating unfluenza
BRPI1013927A2 (pt) métodos e composições para o tratamento de lúpus
HUE063599T2 (hu) Eljárások ödémás fibroszklerotikus pannikulopátia kezelésére vagy csökkentésére
EP2590674A4 (en) COMPOSITIONS AND METHODS FOR INFLUENZA TREATMENT
EP2323579A4 (en) METHODS AND DEVICES FOR TREATING PRESBYOPIA
ZA201303222B (en) Composition and method for treating skin conditions
PL2632550T3 (pl) Sposoby i kompozycja do leczenia biegunki związanej z HIV
BRPI1016257A2 (pt) composições compreendendo finafloxacino e métodos para tratar infecções oftálmicas, ópticas ou nasais
BRPI1009141A2 (pt) composições e métodos para profilaxia e tratamento de vícios