PL2420232T3 - Antagonista receptora angiotensyny II do leczenia nadciśnienia tętniczego u kotów - Google Patents

Antagonista receptora angiotensyny II do leczenia nadciśnienia tętniczego u kotów

Info

Publication number
PL2420232T3
PL2420232T3 PL11186078T PL11186078T PL2420232T3 PL 2420232 T3 PL2420232 T3 PL 2420232T3 PL 11186078 T PL11186078 T PL 11186078T PL 11186078 T PL11186078 T PL 11186078T PL 2420232 T3 PL2420232 T3 PL 2420232T3
Authority
PL
Poland
Prior art keywords
angiotensin
cats
hypertension
treatment
receptor antagonist
Prior art date
Application number
PL11186078T
Other languages
English (en)
Inventor
Marcus Stark
Ulrike Sent
Ingo Lang
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37744125&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2420232(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of PL2420232T3 publication Critical patent/PL2420232T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL11186078T 2006-10-06 2007-10-04 Antagonista receptora angiotensyny II do leczenia nadciśnienia tętniczego u kotów PL2420232T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06121905A EP1908469A1 (en) 2006-10-06 2006-10-06 Angiotensin II receptor antagonist for the treatment of systemic diseases in cats
EP07820908.7A EP2086535B1 (en) 2006-10-06 2007-10-04 Angiotensin ii receptor antagonist for the treatment of systemic diseases in cats
EP11186078.9A EP2420232B1 (en) 2006-10-06 2007-10-04 Angiotensin II receptor antagonist for the treatment of hypertension in cats

Publications (1)

Publication Number Publication Date
PL2420232T3 true PL2420232T3 (pl) 2016-06-30

Family

ID=37744125

Family Applications (4)

Application Number Title Priority Date Filing Date
PL07820908T PL2086535T3 (pl) 2006-10-06 2007-10-04 Antagoniści receptora angiotensyny II do leczenia chorób ogólnoustrojowych u kotów
PL11186080T PL2420233T3 (pl) 2006-10-06 2007-10-04 Antagoniści receptora angiotensyny II do leczenia cukrzycy u kotów
PL11186078T PL2420232T3 (pl) 2006-10-06 2007-10-04 Antagonista receptora angiotensyny II do leczenia nadciśnienia tętniczego u kotów
PL11186070T PL2420231T3 (pl) 2006-10-06 2007-10-04 Antagoniści receptora angiotensyny II do leczenia chorób sercowo-naczyniowych u kotów

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PL07820908T PL2086535T3 (pl) 2006-10-06 2007-10-04 Antagoniści receptora angiotensyny II do leczenia chorób ogólnoustrojowych u kotów
PL11186080T PL2420233T3 (pl) 2006-10-06 2007-10-04 Antagoniści receptora angiotensyny II do leczenia cukrzycy u kotów

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL11186070T PL2420231T3 (pl) 2006-10-06 2007-10-04 Antagoniści receptora angiotensyny II do leczenia chorób sercowo-naczyniowych u kotów

Country Status (25)

Country Link
US (5) US8772278B2 (pl)
EP (5) EP1908469A1 (pl)
JP (5) JP5425631B2 (pl)
KR (2) KR101456151B1 (pl)
CN (6) CN114344293B (pl)
AR (1) AR063155A1 (pl)
BR (4) BRPI0718041A2 (pl)
CA (1) CA2665435C (pl)
CL (2) CL2007002897A1 (pl)
CO (1) CO6180425A2 (pl)
CY (2) CY1114266T1 (pl)
DK (4) DK2420232T3 (pl)
ES (4) ES2562182T3 (pl)
HR (1) HRP20130696T1 (pl)
HU (4) HUE027399T2 (pl)
LU (1) LU92282I2 (pl)
MX (4) MX360147B (pl)
NL (1) NL300616I2 (pl)
NZ (3) NZ597648A (pl)
PL (4) PL2086535T3 (pl)
PT (1) PT2086535E (pl)
SI (1) SI2086535T1 (pl)
TW (3) TWI539949B (pl)
WO (1) WO2008040774A2 (pl)
ZA (1) ZA200901218B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1908469A1 (en) 2006-10-06 2008-04-09 Boehringer Ingelheim Vetmedica Gmbh Angiotensin II receptor antagonist for the treatment of systemic diseases in cats
AR068814A1 (es) * 2007-08-29 2009-12-09 Orion Corp Composicion farmaceutica que comprende levosimendan y un inhibidor de la enzima conversina de la angiotensina (ace), y uso
WO2010097501A2 (en) * 2009-02-26 2010-09-02 Orion Corporation A combination treatment
PL2432452T3 (pl) 2009-05-20 2017-07-31 Boehringer Ingelheim Vetmedica Gmbh Farmaceutyczny pitny roztwór telmisartanu
CN102283832B (zh) * 2011-09-09 2013-04-10 南京正宽医药科技有限公司 一种预防或治疗高血压肥胖患者的药物组合物及用途
MX369832B (es) 2012-05-18 2019-11-22 Luoda Pharma Ltd Formulaciones líquidas que comprenden pimobendan y propilenglicol para el tratamiento de hipertensión y/o enfermedades cardiacas.
DE102012018903A1 (de) 2012-09-26 2014-03-27 Elisabeth Kurth Brustglocke für die manuelle Laktation von Milch aus der weiblichen Brust
CN105233288A (zh) * 2015-09-28 2016-01-13 青岛云天生物技术有限公司 一种治疗或预防肥胖型高血压的药物组合物及其用途
JP6800633B2 (ja) * 2016-07-04 2020-12-16 株式会社カネカ 非ヒト動物において腎機能の低下を抑制する方法
HRP20240703T1 (hr) * 2017-07-07 2024-08-16 Boehringer Ingelheim Vetmedica Gmbh Telmisartan za profilaksu ili liječenje hipertenzije kod mačaka
EP3996709A1 (en) * 2019-07-09 2022-05-18 Boehringer Ingelheim Vetmedica GmbH Telmisartan for the treatment of hypertension in dogs
WO2022145443A1 (ja) * 2020-12-28 2022-07-07 株式会社Cured 慢性腎臓病の治療用医薬組成物
US20240390332A1 (en) 2023-05-24 2024-11-28 Boehringer Ingelheim Vetmedica Gmbh Combination treatment and/or prevention of renal diseases and/or hypertension in non-human mammals comprising one or more SGLT-2 inhibitors and telmisartan

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1023027B (de) 1953-07-10 1958-01-23 Hoffmann La Roche Verfahren zur Herstellung von Polyendialdehyden
JPS5671074A (en) 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative
US4448778A (en) 1981-08-03 1984-05-15 Ici Americas Inc. Maltitol containing gel base systems
CA1334092C (en) 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
CA1338238C (en) 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
US5015651A (en) 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
US4880804A (en) 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
IE70593B1 (en) 1989-09-29 1996-12-11 Eisai Co Ltd Biphenylmethane derivative the use of it and pharmacological compositions containing same
PH30484A (en) 1990-02-19 1997-05-28 Ciba Geigy Acy compounds pharmaceutical composition containing said compound and method of use thereof
IE910913A1 (en) 1990-03-20 1991-09-25 Sanofi Sa N-substituted heterocyclic derivates, their preparation¹and pharmaceutical compositions containing them
US5196444A (en) 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
IE912956A1 (en) 1990-09-10 1992-03-11 Abbott Lab Angiotensin ii receptor antagonists
US6028091A (en) 1990-12-14 2000-02-22 Smithkline Beecham Plc Medicament
GB9027210D0 (en) 1990-12-14 1991-02-06 Smithkline Beecham Plc Medicaments
SI9210098B (sl) 1991-02-06 2000-06-30 Dr. Karl Thomae Benzimidazoli, zdravila, ki te spojine vsebujejo, in postopek za njihovo pripravo
US5591762A (en) 1991-02-06 1997-01-07 Dr. Karl Thomae Gmbh Benzimidazoles useful as angiotensin-11 antagonists
US5196537A (en) 1991-03-21 1993-03-23 G. D. Searle & Co. 5-apylheteroarylalkyl-1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
GB9110636D0 (en) 1991-05-16 1991-07-03 Glaxo Group Ltd Chemical compounds
WO1993020816A1 (en) 1992-04-13 1993-10-28 Zeneca Limited Angiotensin ii antagonists against disorders associated with impaired neuronal conduction velocity, especially diabetic neuropathy
JP3862295B2 (ja) * 1993-09-30 2006-12-27 独立行政法人理化学研究所 抗肥満剤
CA2186606A1 (en) 1994-03-29 1995-10-05 Edward B. Nelson Treatment of atherosclerosis with angiotensin ii receptor blocking imidazoles
HUP9801593A2 (hu) * 1995-04-07 1999-01-28 Novartis Ag. Benazeprilt vagy benazeprilátot és valzartánt tartalmazó kombinált gyógyszerkészítmények és azok alkalmazása
EP0910375B1 (en) * 1996-06-24 2002-05-02 Merck & Co., Inc. A composition of enalapril and losartan
JPH11315034A (ja) * 1998-03-04 1999-11-16 Takeda Chem Ind Ltd アンギオテンシンii拮抗作用を有する化合物の徐放性製剤、その製造法および用途
WO1999044590A1 (en) 1998-03-04 1999-09-10 Takeda Chemical Industries, Ltd. Sustained-release preparation for aii antagonist, production and use thereof
US6204281B1 (en) * 1998-07-10 2001-03-20 Novartis Ag Method of treatment and pharmaceutical composition
DE19901921C2 (de) 1999-01-19 2001-01-04 Boehringer Ingelheim Pharma Polymorphe von Telmisartan, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung eines Arzneimittels
US6358986B1 (en) 1999-01-19 2002-03-19 Boehringer Ingelheim Pharma Kg Polymorphs of telmisartan
DE10018401A1 (de) * 2000-04-13 2001-10-25 Boehringer Ingelheim Pharma Verwendung von Bradycardica bei der Behandlung von mit Hypertrophie einhergehenden Myocarderkrankungen und neue Arzneimittelkombinationen
EP1329217A4 (en) 2000-10-06 2007-04-04 Takeda Pharmaceutical Solid preparations
EP1389105A4 (en) 2001-05-14 2005-08-17 Merck & Co Inc Methods of Treatment
US20040219208A1 (en) * 2001-08-03 2004-11-04 Ryu Kawamura Sustained-release medicines
US6737432B2 (en) 2001-10-31 2004-05-18 Boehringer Ingelheim Pharma Kg Crystalline form of telmisartan sodium
DE10153737A1 (de) 2001-10-31 2003-05-28 Boehringer Ingelheim Pharma Kristallines Natriumsalz des Telmisartans, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
US20060014839A1 (en) * 2002-05-17 2006-01-19 Califf Robert M Combination of angiotensin II receptor blocker and beta-blocker for secondary prevention of myocardial infarction
US7232828B2 (en) 2002-08-10 2007-06-19 Bethesda Pharmaceuticals, Inc. PPAR Ligands that do not cause fluid retention, edema or congestive heart failure
CA2497048A1 (en) * 2002-08-28 2004-03-11 Curis, Inc. Conjoint administration of morphogens and ace inhibitors in treatment of chronic renal failure
US8980870B2 (en) 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations
DE10244681A1 (de) 2002-09-24 2004-04-08 Boehringer Ingelheim International Gmbh Neue feste Telmisartan enthaltende pharmazeutische Formulierungen und deren Herstellung
DE10335027A1 (de) 2003-07-31 2005-02-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von Angiotensin II Rezeptor Antagonisten
WO2005070462A2 (en) * 2004-01-12 2005-08-04 Sepracor, Inc. Compositions comprising (s)-amlodipine and an angiotensin receptor blocker and methods of their use
DE102004008804A1 (de) * 2004-02-20 2005-09-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mehrschichttablette
EP1579862A1 (en) * 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
WO2005123070A1 (en) * 2004-06-09 2005-12-29 Fibrogen, Inc. Dual blockade of renin-angiotensin system reduces connective tissue growth factor levels in diabetic nephropathy
CN1602960A (zh) * 2004-07-23 2005-04-06 海南国栋药物研究所有限公司 一种防治心脑血管病及糖尿病等代谢综合症的复合制剂
CN100364532C (zh) * 2004-09-30 2008-01-30 江苏恒瑞医药股份有限公司 包含氨氯地平和血管紧张素ⅱ受体抑制剂的组合物
DK1814527T4 (da) * 2004-11-05 2020-12-07 Boehringer Ingelheim Int Dobbeltlagstablet omfattende telmisartan og amlodipin
CN1813707A (zh) * 2004-12-01 2006-08-09 鲁南制药集团股份有限公司 用于治疗高血压的含有单硝酸异山梨酯的药物组合物
US20070026026A1 (en) 2005-08-01 2007-02-01 David Delmarre Oral liquid losartan compositions
EP1908469A1 (en) 2006-10-06 2008-04-09 Boehringer Ingelheim Vetmedica Gmbh Angiotensin II receptor antagonist for the treatment of systemic diseases in cats
EP1970053A1 (en) 2007-03-14 2008-09-17 Boehringer Ingelheim Pharma GmbH & Co. KG Pharmaceutical composition
PL2432452T3 (pl) 2009-05-20 2017-07-31 Boehringer Ingelheim Vetmedica Gmbh Farmaceutyczny pitny roztwór telmisartanu

Also Published As

Publication number Publication date
US10357479B2 (en) 2019-07-23
DK2086535T3 (da) 2013-07-22
CN114344293B (zh) 2024-04-19
CN102580095A (zh) 2012-07-18
US20170128423A1 (en) 2017-05-11
HUE027399T2 (en) 2016-09-28
NL300616I2 (pl) 2016-06-01
WO2008040774A3 (en) 2008-07-10
CO6180425A2 (es) 2010-07-19
NZ576109A (en) 2012-02-24
HRP20130696T1 (hr) 2013-09-30
BRPI0718041A2 (pt) 2015-05-12
AR063155A1 (es) 2008-12-30
CA2665435C (en) 2016-03-29
US9585873B2 (en) 2017-03-07
HUS1300062I1 (hu) 2013-11-28
NZ609533A (en) 2014-08-29
KR20090080954A (ko) 2009-07-27
CN114344293A (zh) 2022-04-15
JP2013216709A (ja) 2013-10-24
PL2420233T3 (pl) 2016-07-29
ES2425482T3 (es) 2013-10-15
MX360150B (es) 2018-10-24
DK2420233T3 (en) 2016-04-11
CL2012001349A1 (es) 2012-10-12
LU92282I9 (pl) 2019-01-17
HUE027280T2 (en) 2016-09-28
CY1114266T1 (el) 2015-11-04
CA2665435A1 (en) 2008-04-10
LU92282I2 (fr) 2013-11-19
DK2420231T3 (en) 2016-04-11
JP5899165B2 (ja) 2016-04-06
BR122013019533A2 (pt) 2015-07-14
CN109125730A (zh) 2019-01-04
TWI539949B (zh) 2016-07-01
BR122013019534A2 (pt) 2015-07-14
CN102580095B (zh) 2015-12-09
EP2420233A2 (en) 2012-02-22
CY2013037I1 (el) 2015-11-04
JP6151123B2 (ja) 2017-06-21
ES2567041T3 (es) 2016-04-19
CN101522191B (zh) 2012-05-16
TWI539950B (zh) 2016-07-01
PL2086535T3 (pl) 2013-10-31
TWI415605B (zh) 2013-11-21
EP2420231B1 (en) 2016-01-13
EP2086535B1 (en) 2013-05-22
MX360147B (es) 2018-10-24
EP2420233A3 (en) 2012-04-18
KR101529541B1 (ko) 2015-06-17
JP2016094436A (ja) 2016-05-26
WO2008040774A2 (en) 2008-04-10
JP6337170B2 (ja) 2018-06-06
EP2420231A2 (en) 2012-02-22
EP2086535A2 (en) 2009-08-12
JP2013216708A (ja) 2013-10-24
MX2009002340A (es) 2009-03-23
PL2420231T3 (pl) 2016-07-29
CN101522191A (zh) 2009-09-02
MX360148B (es) 2018-10-24
TW200831078A (en) 2008-08-01
AU2007304216A1 (en) 2008-04-10
US8772278B2 (en) 2014-07-08
KR101456151B1 (ko) 2014-11-04
CN105148272A (zh) 2015-12-16
EP1908469A1 (en) 2008-04-09
JP2017122115A (ja) 2017-07-13
HUS1800044I1 (hu) 2018-12-28
US9308197B2 (en) 2016-04-12
ES2565519T3 (es) 2016-04-05
US20180193317A1 (en) 2018-07-12
ES2562182T3 (es) 2016-03-02
EP2420231A3 (en) 2012-04-11
EP2420232A2 (en) 2012-02-22
ZA200901218B (en) 2010-03-31
CL2007002897A1 (es) 2008-03-07
KR20140088601A (ko) 2014-07-10
BR122013019535A2 (pt) 2015-07-14
US9949954B2 (en) 2018-04-24
EP2420232B1 (en) 2016-01-06
CN102512678A (zh) 2012-06-27
US20140288138A1 (en) 2014-09-25
JP2010505796A (ja) 2010-02-25
SI2086535T1 (sl) 2013-09-30
DK2420232T3 (en) 2016-03-07
US20130190373A1 (en) 2013-07-25
JP5425631B2 (ja) 2014-02-26
TW201332547A (zh) 2013-08-16
AU2007304216B2 (en) 2013-06-13
EP2420232A3 (en) 2012-05-02
US20080146543A1 (en) 2008-06-19
CY2013037I2 (el) 2015-11-04
TW201402115A (zh) 2014-01-16
PT2086535E (pt) 2013-08-22
NZ597648A (en) 2013-05-31
EP2420233B1 (en) 2016-01-13

Similar Documents

Publication Publication Date Title
HUS1800044I1 (hu) Angiotenzin-II-receptor antagonisták macskák magas vérnyomásának kezelésére
HUS1600025I1 (hu) Egy angiotenzin receptor antagonistát és egy NEP inhibitort tartalmazó gyógyászati kombinációk
IL198650A0 (en) Progesterone receptor antagonists
ZA200907094B (en) Gonadotropin-releasing hormone receptor antagonists and methods relating thereto
PL2137191T3 (pl) Antagoniści obwodowego receptora opioidowego i ich zastosowania
HRP20150661T1 (en) Peripheral opioid receptor and antagonists and uses thereof
IL195807A0 (en) Cgrp receptor antagonists
ZA200904479B (en) Nitroderivatives as angiotensin II receptor antagonists
IL192693A0 (en) Urotensin ii receptor antagonists
EP1874302A4 (en) ANTAGONISTS OF ANGIOTENSIN II RECEPTORS
IL196758A0 (en) Urotensin ii receptor antagonists
ZA200903499B (en) Indoles which act as via receptor antagonists
ZA200810681B (en) Treating obesity with muscaring receptor mi antagonists
GB2450580B (en) Poly-TLR antagonist
IL193427A0 (en) Polypeptide antagonist
ZA200704717B (en) Pharmaceutical combinations of an angiotensin receptor antagonist and an NEP inhibitor
IL162631A0 (en) Disease treatment via inhibition ofil1 receptor anDisease treatment via inhibition ofil1 receptor antagonist tagonist
ZA200906849B (en) Mineralcorticoid receptor antagonists for the treatment of endomertriosis
AU2006905576A0 (en) Novel Angiotensin II Antagonists