PL2364989T3 - Stabilne pochodne NAD/NADH - Google Patents

Stabilne pochodne NAD/NADH

Info

Publication number
PL2364989T3
PL2364989T3 PL11167476T PL11167476T PL2364989T3 PL 2364989 T3 PL2364989 T3 PL 2364989T3 PL 11167476 T PL11167476 T PL 11167476T PL 11167476 T PL11167476 T PL 11167476T PL 2364989 T3 PL2364989 T3 PL 2364989T3
Authority
PL
Poland
Prior art keywords
nadh
derivatives
stable nad
nad
stable
Prior art date
Application number
PL11167476T
Other languages
English (en)
Polish (pl)
Inventor
Joachim Hoenes
Dieter Heindl
Carina Horn
Claudia Gaessler-Dietsche
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PL2364989T3 publication Critical patent/PL2364989T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL11167476T 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH PL2364989T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005035461A DE102005035461A1 (de) 2005-07-28 2005-07-28 Stabile NAD/NADH-Derivate
EP11167476.8A EP2364989B1 (de) 2005-07-28 2006-07-28 Stabile NAD/NADH-Derivate
EP06776486.0A EP1907408B1 (de) 2005-07-28 2006-07-28 Stabile nad/nadh-derivate

Publications (1)

Publication Number Publication Date
PL2364989T3 true PL2364989T3 (pl) 2014-08-29

Family

ID=37137552

Family Applications (3)

Application Number Title Priority Date Filing Date
PL11167476T PL2364989T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH
PL11167471T PL2364988T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH
PL06776486T PL1907408T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH

Family Applications After (2)

Application Number Title Priority Date Filing Date
PL11167471T PL2364988T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH
PL06776486T PL1907408T3 (pl) 2005-07-28 2006-07-28 Stabilne pochodne NAD/NADH

Country Status (16)

Country Link
US (3) US8809013B2 (enExample)
EP (3) EP2364988B1 (enExample)
JP (2) JP5129133B2 (enExample)
KR (4) KR101483899B1 (enExample)
CN (2) CN103122371B (enExample)
AU (2) AU2006274140B8 (enExample)
BR (1) BRPI0614217A2 (enExample)
CA (2) CA2614792C (enExample)
DE (1) DE102005035461A1 (enExample)
DK (3) DK2364989T3 (enExample)
ES (3) ES2461624T3 (enExample)
MX (1) MX2008000946A (enExample)
PL (3) PL2364989T3 (enExample)
PT (3) PT2364989E (enExample)
SG (1) SG187511A1 (enExample)
WO (1) WO2007012494A1 (enExample)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4786451B2 (ja) * 2005-07-28 2011-10-05 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト Ｎａｄ／ｎａｄｈの安定化
DE102005035461A1 (de) * 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate
EP2022859A1 (de) * 2007-08-01 2009-02-11 Roche Diagnostics GmbH Verfahren und Vorrichtung zur Bestimmung der Konzentration eines Analyten mittels Fluoreszenzmessung
CN101497638B (zh) * 2008-01-30 2012-09-26 中国科学院大连化学物理研究所 一种nad+类似物及其合成和应用
WO2010094632A1 (de) 2009-02-19 2010-08-26 F. Hoffmann-La Roche Ag Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten
EP2093284A1 (de) * 2008-02-19 2009-08-26 F.Hoffmann-La Roche Ag Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
EP2226008A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Verfahren zur Herstellung eines analytischen Magazins
EP2398909B1 (de) 2009-02-19 2015-07-22 F. Hoffmann-La Roche AG Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten
EP2226007A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Testelementmagazin mit abgedeckten Testfeldern
CN102325496B (zh) * 2009-02-19 2015-10-07 霍夫曼-拉罗奇有限公司 分析辅助工具的节省空间的储存
CA2769156C (en) * 2009-07-27 2015-02-10 F. Hoffmann-La Roche Ag Method and substances for preparation of n-substituted pyridinium compounds
JP5542931B2 (ja) * 2009-07-27 2014-07-09 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト Ｎ置換ピリジニウム化合物の調製のための方法及び物質
CA2769155C (en) * 2009-07-27 2015-04-28 F. Hoffmann-La Roche Ag Enzymatic synthesis of carba-nad
EP2287605A1 (de) 2009-08-20 2011-02-23 Roche Diagnostics GmbH Vereinfachte Magazinierung integrierter Systeme
EP2292751A1 (de) 2009-08-20 2011-03-09 Roche Diagnostics GmbH Stabilisierung von Enzymen mit stabilen Coenzymen
EP2333544A1 (de) 2009-12-11 2011-06-15 F. Hoffmann-La Roche AG Sterilisierbare Chemie für Testelemente
JP5777633B2 (ja) 2009-12-16 2015-09-09 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 保護された分析物の制御された放出によるテストエレメントにおける酵素の分解の検出
KR101252351B1 (ko) * 2010-05-24 2013-04-08 동국대학교 산학협력단 전기효소적 합성 반응을 위한 ｎａｄ(ｐ) 유도체의 전기화학적 환원 방법
CN102453067B (zh) * 2010-10-29 2015-08-05 中国科学院大连化学物理研究所 一种nad+类似物的制备方法及其应用
CA2819989C (en) 2011-01-26 2019-03-12 Peter Gebauer Method and substances for preparation of n-substituted pyridinium compounds
US9752990B2 (en) 2013-09-30 2017-09-05 Honeywell International Inc. Low-powered system for driving a fuel control mechanism
MX342218B (es) 2011-04-12 2016-09-21 Hoffmann La Roche Dispositivo analitico.
CN102863495A (zh) * 2011-07-06 2013-01-09 上海执诚生物科技股份有限公司 一种含有nad+或nadh的稳定的组合物
CN103958463A (zh) 2011-09-28 2014-07-30 霍夫曼-拉罗奇有限公司 偶氮介体
JP6128808B2 (ja) * 2011-11-15 2017-05-17 栄研化学株式会社 酵素活性の検出、測定方法およびこれを利用したキット
EP2620507A1 (en) 2012-01-25 2013-07-31 Roche Diagnostics GmbH Method for the evaluation of the quality of a test element
EP2636750A1 (en) 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
EP2839267B1 (de) 2012-04-19 2019-12-04 F.Hoffmann-La Roche Ag Verfahren und vorrichtung zur bestimmung einer analytkonzentration in blut
US8921061B2 (en) * 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
WO2014096174A1 (en) 2012-12-20 2014-06-26 Roche Diagnostics Gmbh Method for evaluating medical measurement curves
CN104854457B (zh) 2012-12-20 2016-09-14 霍夫曼-拉罗奇有限公司 用于分析体液样本的方法
EP2770064A1 (de) 2013-02-22 2014-08-27 F. Hoffmann-La Roche AG Hocheffiziente Herstellung von Blutglucose-Teststreifen
EP2781919A1 (en) 2013-03-19 2014-09-24 Roche Diagniostics GmbH Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid
WO2014180939A1 (en) 2013-05-08 2014-11-13 Roche Diagnostics Gmbh Stabilization of enzymes by nicotinic acid
JP2016528175A (ja) * 2013-06-04 2016-09-15 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｆｒｅｔに有用な新規化合物およびそれに関連する方法
EP2811299A1 (en) 2013-06-07 2014-12-10 Roche Diagniostics GmbH Test element for detecting at least one analyte in a body fluid
WO2015063025A1 (en) 2013-10-29 2015-05-07 F. Hoffmann-La Roche Ag Nano-enzyme containers for test elements
WO2015078899A1 (en) 2013-11-27 2015-06-04 Roche Diagnostics Gmbh Composition comprising up-converting phosphors for detecting an analyte
EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
JP6522003B2 (ja) 2014-04-14 2019-05-29 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ フェナジニウムメディエーター
US20170233787A1 (en) * 2014-08-05 2017-08-17 Becton, Dickinson And Company Methods and compositions for analyzing glucose-6-phosphate dehydrogenase activity in blood samples
EP3757096B1 (en) 2014-08-22 2025-03-12 Roche Diagnostics GmbH Redoxindicators for a use in cell viability testing
CN113444764B (zh) 2014-08-25 2024-04-19 豪夫迈·罗氏有限公司 对两个电极测试条进行干扰补偿
KR20180087329A (ko) 2015-12-21 2018-08-01 에프. 호프만-라 로슈 아게 알칼리게네스 파에칼리스로부터의 돌연변이체 3-히드록시부티레이트 탈수소효소 뿐만 아니라 이의 관련 방법 및 용도
JP6989528B2 (ja) 2016-02-09 2022-01-05 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft ロドバクター・スフェロイデス（Ｒｈｏｄｏｂａｃｔｅｒ ｓｐｈａｅｒｏｉｄｅｓ）由来の変異型３−ヒドロキシブチレート脱水素酵素及びそれを含む方法
CA3035874C (en) 2016-10-05 2025-09-09 F. Hoffmann-La Roche Ag DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTICAL DIAGNOSTIC TEST ELEMENTS, AS WELL AS THEIR METHODS OF USE
EP3339431A1 (en) 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Glucose dehydrogenase variants with improved properties
CN107966555A (zh) * 2017-11-23 2018-04-27 中山市创艺生化工程有限公司 一种用于稳定保存nad或其衍生物的存储液
HUE064713T2 (hu) 2018-02-28 2024-04-28 Hoffmann La Roche Biokompatibilitási bevonat folyamatos analitméréshez
CN111217744A (zh) * 2018-11-26 2020-06-02 中国科学院大连化学物理研究所 一种d-氨基酸基nad+类似物及其合成和应用
AU2021400588B2 (en) 2020-12-15 2025-04-10 Abbott Diabetes Care Inc. Nad(p) depot for nad(p)-dependent enzyme-based sensors
WO2025245355A1 (en) 2024-05-24 2025-11-27 Abbott Diabetes Care Inc. Dispensed area and drop solid content tunability

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53107486A (en) * 1977-02-28 1978-09-19 Wako Pure Chem Ind Ltd Stabilized nadh aqueous solution
JPS61274636A (ja) 1985-05-30 1986-12-04 西南自動車工業株式会社 活魚水槽
US5801006A (en) 1997-02-04 1998-09-01 Specialty Assays, Inc. Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites
JP4260245B2 (ja) * 1998-06-25 2009-04-30 株式会社三菱化学ヤトロン 還元型ニコチンアミドアデニンジヌクレオチド類の分解を防止する方法及び分解防止用試薬
US6380380B1 (en) 1999-01-04 2002-04-30 Specialty Assays, Inc. Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates
WO2001094370A1 (en) 2000-06-07 2001-12-13 Wako Pure Chemical Industries, Ltd. Coenzyme derivatives and enzymes appropriate therefor
AU2003240260B2 (en) 2002-05-16 2008-05-22 F. Hoffmann-La Roche Ag Method and reagent system having a non-regenerative enzyme-coenzyme complex
DE10221845A1 (de) 2002-05-16 2003-11-27 Roche Diagnostics Gmbh Verfahren und Reagenzsystem mit nicht-regenerierbarem Enzym-Coenzym-Komplex
DE102005035461A1 (de) * 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate

Also Published As

Publication number Publication date
KR101483829B1 (ko) 2015-01-16
KR20110028522A (ko) 2011-03-18
MX2008000946A (es) 2008-03-27
CN101233144B (zh) 2013-02-06
AU2006274140B2 (en) 2010-11-11
US20160326567A1 (en) 2016-11-10
EP2364989B1 (de) 2014-03-05
ES2453150T3 (es) 2014-04-04
EP1907408A1 (de) 2008-04-09
KR20080028507A (ko) 2008-03-31
PL1907408T3 (pl) 2014-07-31
CN103122371A (zh) 2013-05-29
DK2364989T3 (da) 2014-06-10
DK1907408T3 (da) 2014-06-10
CN103122371B (zh) 2016-12-28
AU2006274140A1 (en) 2007-02-01
CA2737123A1 (en) 2007-02-01
KR20140003637A (ko) 2014-01-09
AU2011200465A1 (en) 2011-02-24
DK2364988T3 (da) 2014-05-26
EP2364988B1 (de) 2014-02-26
JP5650695B2 (ja) 2015-01-07
PT2364988E (pt) 2014-04-03
SG187511A1 (en) 2013-02-28
BRPI0614217A2 (pt) 2011-03-22
ES2461624T3 (es) 2014-05-20
PT2364989E (pt) 2014-04-04
US9399790B2 (en) 2016-07-26
US20140206024A1 (en) 2014-07-24
CN101233144A (zh) 2008-07-30
WO2007012494A1 (de) 2007-02-01
AU2011200465B2 (en) 2012-02-09
CA2614792A1 (en) 2007-02-01
AU2006274140B8 (en) 2011-02-03
US10167497B2 (en) 2019-01-01
PL2364988T3 (pl) 2014-08-29
US20080213809A1 (en) 2008-09-04
EP1907408B1 (de) 2014-03-05
JP2009502844A (ja) 2009-01-29
EP2364989A1 (de) 2011-09-14
KR101035524B1 (ko) 2011-05-23
KR101483899B1 (ko) 2015-01-16
KR20120044372A (ko) 2012-05-07
JP5129133B2 (ja) 2013-01-23
HK1123308A1 (en) 2009-06-12
ES2461266T3 (es) 2014-05-19
US8809013B2 (en) 2014-08-19
DE102005035461A1 (de) 2007-02-15
CA2614792C (en) 2011-07-12
WO2007012494B1 (de) 2007-03-29
PT1907408E (pt) 2014-03-28
EP2364988A1 (de) 2011-09-14
JP2012224638A (ja) 2012-11-15

Similar Documents

Publication Publication Date Title
PL2364989T3 (pl) Stabilne pochodne NAD/NADH
DE502006001600D1 (en) Pyrazolylcarboxanilide
DE602006018441D1 (en) Arabinofuranosidasen
DE602006018627D1 (en) Cholesterol-absorptionsinhibitor
DE602006013270D1 (en) Prrs-impfstoffe
DE602006017073D1 (en) Aspartylproteasehemmer
DE602006016093D1 (en) Cyanoanthranilamidinsektizide
DK1866498T3 (en) C-profil
EP1871379A4 (en) CYANOARYLAMINE
DE602006003064D1 (en) Tripeptid- und tetrapeptid-thioether
DE602006009492D1 (en) Fluidmaschinen
DE602006016951D1 (en) 2-cyanoacrylatzusammensetzung
DE502005007477D1 (en) Delta-sigma-modulator
DE602006021065D1 (en) Lithium-batteriepack
EP1871655A4 (en) TRIGGER OPERATION FOR SIDE DRIVE
EP1871796A4 (en) VESICULINE
GB0506800D0 (en) New uses
DE502006002219D1 (en) Rotationspumpe
DE602006015303D1 (en) Lecknachweisflicken
DE502006007734D1 (en) Thiazolcarbonsäureanilide
GB2424168B (en) Stable aid
GB0522564D0 (en) Cells
GB0613762D0 (en) Slabline structure
GB0503644D0 (en) Catstep I
AU3401P (en) Archise Arctotis fastuosa