DK2364988T3 - Stabile NAD/NADH-derivater - Google Patents
Stabile NAD/NADH-derivaterInfo
- Publication number
- DK2364988T3 DK2364988T3 DK11167471.9T DK11167471T DK2364988T3 DK 2364988 T3 DK2364988 T3 DK 2364988T3 DK 11167471 T DK11167471 T DK 11167471T DK 2364988 T3 DK2364988 T3 DK 2364988T3
- Authority
- DK
- Denmark
- Prior art keywords
- stable nad
- nadh derivatives
- nadh
- derivatives
- nad
- Prior art date
Links
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical class C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
- C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005035461A DE102005035461A1 (de) | 2005-07-28 | 2005-07-28 | Stabile NAD/NADH-Derivate |
| EP06776486.0A EP1907408B1 (de) | 2005-07-28 | 2006-07-28 | Stabile nad/nadh-derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2364988T3 true DK2364988T3 (da) | 2014-05-26 |
Family
ID=37137552
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK11167471.9T DK2364988T3 (da) | 2005-07-28 | 2006-07-28 | Stabile NAD/NADH-derivater |
| DK06776486.0T DK1907408T3 (da) | 2005-07-28 | 2006-07-28 | Stabile NAD/NADH-derivater |
| DK11167476.8T DK2364989T3 (da) | 2005-07-28 | 2006-07-28 | Stabile NAD/NADH-derivater |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06776486.0T DK1907408T3 (da) | 2005-07-28 | 2006-07-28 | Stabile NAD/NADH-derivater |
| DK11167476.8T DK2364989T3 (da) | 2005-07-28 | 2006-07-28 | Stabile NAD/NADH-derivater |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US8809013B2 (enExample) |
| EP (3) | EP2364989B1 (enExample) |
| JP (2) | JP5129133B2 (enExample) |
| KR (4) | KR101483899B1 (enExample) |
| CN (2) | CN103122371B (enExample) |
| AU (2) | AU2006274140B8 (enExample) |
| BR (1) | BRPI0614217A2 (enExample) |
| CA (2) | CA2737123A1 (enExample) |
| DE (1) | DE102005035461A1 (enExample) |
| DK (3) | DK2364988T3 (enExample) |
| ES (3) | ES2453150T3 (enExample) |
| MX (1) | MX2008000946A (enExample) |
| PL (3) | PL1907408T3 (enExample) |
| PT (3) | PT2364988E (enExample) |
| SG (1) | SG187511A1 (enExample) |
| WO (1) | WO2007012494A1 (enExample) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7553615B2 (en) * | 2005-07-28 | 2009-06-30 | Roche Diagnostics Operations, Inc. | Compounds, methods, complexes, apparatuses and uses relating to stabile forms of NAD/NADH |
| DE102005035461A1 (de) * | 2005-07-28 | 2007-02-15 | Roche Diagnostics Gmbh | Stabile NAD/NADH-Derivate |
| EP2022859A1 (de) * | 2007-08-01 | 2009-02-11 | Roche Diagnostics GmbH | Verfahren und Vorrichtung zur Bestimmung der Konzentration eines Analyten mittels Fluoreszenzmessung |
| CN101497638B (zh) * | 2008-01-30 | 2012-09-26 | 中国科学院大连化学物理研究所 | 一种nad+类似物及其合成和应用 |
| EP2093284A1 (de) * | 2008-02-19 | 2009-08-26 | F.Hoffmann-La Roche Ag | Stabilisierung von Dehydrogenasen mit stabilen Coenzymen |
| EP2226008A1 (de) | 2009-02-19 | 2010-09-08 | Roche Diagnostics GmbH | Verfahren zur Herstellung eines analytischen Magazins |
| EP2226007A1 (de) | 2009-02-19 | 2010-09-08 | Roche Diagnostics GmbH | Testelementmagazin mit abgedeckten Testfeldern |
| KR101604624B1 (ko) * | 2009-02-19 | 2016-03-28 | 에프. 호프만-라 로슈 아게 | 건식 화학 층에서 낮은 활성을 갖는 효소의 고속 반응 속도 |
| WO2010094427A2 (de) * | 2009-02-19 | 2010-08-26 | Roche Diagnostics Gmbh | Platzsparende magazinierung analytischer hilfsmittel |
| EP2398909B1 (de) | 2009-02-19 | 2015-07-22 | F. Hoffmann-La Roche AG | Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten |
| EP2459728B1 (en) * | 2009-07-27 | 2013-06-05 | Roche Diagnostics GmbH | Enzymatic synthesis of carba-NAD |
| WO2011012269A2 (en) | 2009-07-27 | 2011-02-03 | Roche Diagnostics Gmbh | Method and substances for preparation of n-substituted pyridinium compounds |
| EP2459536B1 (en) | 2009-07-27 | 2014-10-29 | Roche Diagnostics GmbH | Method and substances for preparation of n-substituted pyridinium compounds |
| EP2292751A1 (de) * | 2009-08-20 | 2011-03-09 | Roche Diagnostics GmbH | Stabilisierung von Enzymen mit stabilen Coenzymen |
| EP2287605A1 (de) * | 2009-08-20 | 2011-02-23 | Roche Diagnostics GmbH | Vereinfachte Magazinierung integrierter Systeme |
| EP2333544A1 (de) | 2009-12-11 | 2011-06-15 | F. Hoffmann-La Roche AG | Sterilisierbare Chemie für Testelemente |
| CA2782943C (en) | 2009-12-16 | 2014-09-09 | F. Hoffmann-La Roche Ag | Detecting the decomposition of enzymes in a test element by means of controlled release of a protected analyte |
| KR101252351B1 (ko) * | 2010-05-24 | 2013-04-08 | 동국대학교 산학협력단 | 전기효소적 합성 반응을 위한 ｎａｄ(ｐ) 유도체의 전기화학적 환원 방법 |
| CN102453067B (zh) * | 2010-10-29 | 2015-08-05 | 中国科学院大连化学物理研究所 | 一种nad+类似物的制备方法及其应用 |
| WO2012101095A1 (en) | 2011-01-26 | 2012-08-02 | Roche Diagnostics Gmbh | Method and substances for preparation of n-substituted pyridinium compounds |
| US9752990B2 (en) | 2013-09-30 | 2017-09-05 | Honeywell International Inc. | Low-powered system for driving a fuel control mechanism |
| WO2012140027A1 (de) | 2011-04-12 | 2012-10-18 | Roche Diagnostics Gmbh | Analytisches hilfsmittel |
| CN102863495A (zh) * | 2011-07-06 | 2013-01-09 | 上海执诚生物科技股份有限公司 | 一种含有nad+或nadh的稳定的组合物 |
| EP2760825B1 (de) | 2011-09-28 | 2016-09-14 | F.Hoffmann-La Roche Ag | Azomediatoren |
| JP6128808B2 (ja) * | 2011-11-15 | 2017-05-17 | 栄研化学株式会社 | 酵素活性の検出、測定方法およびこれを利用したキット |
| EP2620507A1 (en) | 2012-01-25 | 2013-07-31 | Roche Diagnostics GmbH | Method for the evaluation of the quality of a test element |
| EP2636750A1 (en) | 2012-03-06 | 2013-09-11 | Roche Diagniostics GmbH | Compatible solute ectoine as well as derivatives thereof for enzyme stabilization |
| JP6111323B2 (ja) | 2012-04-19 | 2017-04-05 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | 血液中の検体濃度を測定する方法および装置 |
| US8920628B2 (en) | 2012-11-02 | 2014-12-30 | Roche Diagnostics Operations, Inc. | Systems and methods for multiple analyte analysis |
| US8921061B2 (en) | 2012-11-02 | 2014-12-30 | Roche Diagnostics Operations, Inc. | Reagent materials and associated test elements |
| WO2014096184A1 (en) | 2012-12-20 | 2014-06-26 | Roche Diagnostics Gmbh | Method for analyzing a sample of a body fluid |
| CA2896152C (en) | 2012-12-20 | 2018-07-24 | F. Hoffmann-La Roche Ag | Method for evaluating medical measurement curves |
| EP2770064A1 (de) | 2013-02-22 | 2014-08-27 | F. Hoffmann-La Roche AG | Hocheffiziente Herstellung von Blutglucose-Teststreifen |
| EP2781919A1 (en) | 2013-03-19 | 2014-09-24 | Roche Diagniostics GmbH | Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid |
| WO2014180939A1 (en) | 2013-05-08 | 2014-11-13 | Roche Diagnostics Gmbh | Stabilization of enzymes by nicotinic acid |
| HK1213296A1 (zh) * | 2013-06-04 | 2016-06-30 | 豪夫迈‧罗氏有限公司 | 用於fret的新化合物及与其相关的方法 |
| EP2811299A1 (en) | 2013-06-07 | 2014-12-10 | Roche Diagniostics GmbH | Test element for detecting at least one analyte in a body fluid |
| EP3063169B1 (en) | 2013-10-29 | 2018-10-10 | F. Hoffmann-La Roche AG | Nano-enzyme containers for test elements |
| EP3074524B1 (en) | 2013-11-27 | 2019-11-06 | Roche Diabetes Care GmbH | Composition comprising up-converting phosphors for detecting an analyte |
| EP2927319A1 (en) | 2014-03-31 | 2015-10-07 | Roche Diagnostics GmbH | High load enzyme immobilization by crosslinking |
| CN106164054B (zh) | 2014-04-14 | 2019-05-07 | 豪夫迈·罗氏有限公司 | 吩嗪介导剂 |
| CN106687812A (zh) * | 2014-08-05 | 2017-05-17 | 贝克顿·迪金森公司 | 用于分析血液样品中的葡萄糖‑6‑磷酸脱氢酶活性的方法和组合物 |
| WO2016026959A1 (en) | 2014-08-22 | 2016-02-25 | Roche Diagnostics Gmbh | Redoxindicators |
| BR112017001444B1 (pt) | 2014-08-25 | 2022-08-16 | F. Hoffmann-La Roche Ag | Método para detectar pelo menos um analito em uma amostra de teste, elemento sensor, dispositivo de teste, sistema de teste, uso do elemento sensor e portador de dados |
| KR20180087329A (ko) | 2015-12-21 | 2018-08-01 | 에프. 호프만-라 로슈 아게 | 알칼리게네스 파에칼리스로부터의 돌연변이체 3-히드록시부티레이트 탈수소효소 뿐만 아니라 이의 관련 방법 및 용도 |
| WO2017137491A1 (en) | 2016-02-09 | 2017-08-17 | Roche Diabetes Care Gmbh | Mutant 3-hydroxybutyrate dehydrogenase from rhodobacter sphaeroides as well as methods and uses involving the same |
| CN109804240A (zh) | 2016-10-05 | 2019-05-24 | 豪夫迈·罗氏有限公司 | 用于多分析物诊断测试元件的检测试剂和电极布置以及其使用方法 |
| EP3339431A1 (en) | 2016-12-22 | 2018-06-27 | Roche Diabetes Care GmbH | Glucose dehydrogenase variants with improved properties |
| CN107966555A (zh) * | 2017-11-23 | 2018-04-27 | 中山市创艺生化工程有限公司 | 一种用于稳定保存nad或其衍生物的存储液 |
| CN111801425B (zh) | 2018-02-28 | 2024-02-23 | 豪夫迈·罗氏有限公司 | 用于连续分析物测量的生物相容性涂层 |
| CN111217744A (zh) * | 2018-11-26 | 2020-06-02 | 中国科学院大连化学物理研究所 | 一种d-氨基酸基nad+类似物及其合成和应用 |
| WO2022132963A1 (en) | 2020-12-15 | 2022-06-23 | Abbott Diabetes Care Inc. | Nad(p) depot for nad(p)-dependent enzyme-based sensors |
| WO2025245355A1 (en) | 2024-05-24 | 2025-11-27 | Abbott Diabetes Care Inc. | Dispensed area and drop solid content tunability |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53107486A (en) * | 1977-02-28 | 1978-09-19 | Wako Pure Chem Ind Ltd | Stabilized nadh aqueous solution |
| JPS61274636A (ja) | 1985-05-30 | 1986-12-04 | 西南自動車工業株式会社 | 活魚水槽 |
| US5801006A (en) * | 1997-02-04 | 1998-09-01 | Specialty Assays, Inc. | Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites |
| JP4260245B2 (ja) * | 1998-06-25 | 2009-04-30 | 株式会社三菱化学ヤトロン | 還元型ニコチンアミドアデニンジヌクレオチド類の分解を防止する方法及び分解防止用試薬 |
| US6380380B1 (en) | 1999-01-04 | 2002-04-30 | Specialty Assays, Inc. | Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates |
| WO2001094370A1 (en) | 2000-06-07 | 2001-12-13 | Wako Pure Chemical Industries, Ltd. | Coenzyme derivatives and enzymes appropriate therefor |
| DE10221845A1 (de) | 2002-05-16 | 2003-11-27 | Roche Diagnostics Gmbh | Verfahren und Reagenzsystem mit nicht-regenerierbarem Enzym-Coenzym-Komplex |
| DK1504113T3 (da) | 2002-05-16 | 2007-03-05 | Hoffmann La Roche | Fremgangsmåde til fremstilling af polymerlag |
| DE102005035461A1 (de) * | 2005-07-28 | 2007-02-15 | Roche Diagnostics Gmbh | Stabile NAD/NADH-Derivate |
-
2005
- 2005-07-28 DE DE102005035461A patent/DE102005035461A1/de not_active Withdrawn
-
2006
- 2006-07-28 PT PT111674719T patent/PT2364988E/pt unknown
- 2006-07-28 AU AU2006274140A patent/AU2006274140B8/en not_active Ceased
- 2006-07-28 KR KR20137030825A patent/KR101483899B1/ko not_active Expired - Fee Related
- 2006-07-28 DK DK11167471.9T patent/DK2364988T3/da active
- 2006-07-28 BR BRPI0614217-6A patent/BRPI0614217A2/pt not_active IP Right Cessation
- 2006-07-28 EP EP11167476.8A patent/EP2364989B1/de active Active
- 2006-07-28 JP JP2008523257A patent/JP5129133B2/ja active Active
- 2006-07-28 CA CA2737123A patent/CA2737123A1/en active Pending
- 2006-07-28 EP EP06776486.0A patent/EP1907408B1/de active Active
- 2006-07-28 PT PT111674768T patent/PT2364989E/pt unknown
- 2006-07-28 DK DK06776486.0T patent/DK1907408T3/da active
- 2006-07-28 CN CN201210559220.9A patent/CN103122371B/zh active Active
- 2006-07-28 ES ES11167471.9T patent/ES2453150T3/es active Active
- 2006-07-28 PL PL06776486T patent/PL1907408T3/pl unknown
- 2006-07-28 PL PL11167476T patent/PL2364989T3/pl unknown
- 2006-07-28 WO PCT/EP2006/007493 patent/WO2007012494A1/de not_active Ceased
- 2006-07-28 MX MX2008000946A patent/MX2008000946A/es active IP Right Grant
- 2006-07-28 PT PT67764860T patent/PT1907408E/pt unknown
- 2006-07-28 EP EP11167471.9A patent/EP2364988B1/de active Active
- 2006-07-28 PL PL11167471T patent/PL2364988T3/pl unknown
- 2006-07-28 KR KR1020087004422A patent/KR101035524B1/ko not_active Expired - Fee Related
- 2006-07-28 KR KR20127005354A patent/KR101483829B1/ko not_active Expired - Fee Related
- 2006-07-28 SG SG2013005301A patent/SG187511A1/en unknown
- 2006-07-28 CN CN2006800273591A patent/CN101233144B/zh active Active
- 2006-07-28 KR KR1020117002057A patent/KR20110028522A/ko not_active Ceased
- 2006-07-28 ES ES11167476.8T patent/ES2461624T3/es active Active
- 2006-07-28 ES ES06776486.0T patent/ES2461266T3/es active Active
- 2006-07-28 CA CA2614792A patent/CA2614792C/en active Active
- 2006-07-28 DK DK11167476.8T patent/DK2364989T3/da active
-
2008
- 2008-01-25 US US12/020,244 patent/US8809013B2/en active Active
-
2011
- 2011-02-04 AU AU2011200465A patent/AU2011200465B2/en not_active Revoked
-
2012
- 2012-08-03 JP JP2012172878A patent/JP5650695B2/ja active Active
-
2014
- 2014-03-23 US US14/222,645 patent/US9399790B2/en active Active
-
2016
- 2016-07-20 US US15/214,494 patent/US10167497B2/en active Active
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