PL2326735T3 - Zmiany genetyczne w dehydrogenazie izocytrynianowej i innych genach w glejaku złośliwym - Google Patents

Zmiany genetyczne w dehydrogenazie izocytrynianowej i innych genach w glejaku złośliwym

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Publication number
PL2326735T3
PL2326735T3 PL09792198T PL09792198T PL2326735T3 PL 2326735 T3 PL2326735 T3 PL 2326735T3 PL 09792198 T PL09792198 T PL 09792198T PL 09792198 T PL09792198 T PL 09792198T PL 2326735 T3 PL2326735 T3 PL 2326735T3
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PL
Poland
Prior art keywords
genes
genetic alterations
malignant glioma
isocitrate dehydrogenase
isocitrate
Prior art date
Application number
PL09792198T
Other languages
English (en)
Inventor
Bert Vogelstein
Kenneth W. Kinzler
D. Williams Parsons
Xiaosong Zhang
Jimmy Cheng-Ho Lin
Rebecca J. Leary
Philipp Angenendt
Nickolas Papadopoulos
Victor Velculescu
Giovanni Parmigiani
Rachel Karchin
Sian Jones
Hai Yan
Darell Bigner
Chien-Tsun Kuan
Gregory J. Riggins
Original Assignee
The Johns Hopkins University
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Johns Hopkins University, Duke University filed Critical The Johns Hopkins University
Publication of PL2326735T3 publication Critical patent/PL2326735T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
PL09792198T 2008-09-03 2009-09-03 Zmiany genetyczne w dehydrogenazie izocytrynianowej i innych genach w glejaku złośliwym PL2326735T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9373908P 2008-09-03 2008-09-03
US11039708P 2008-10-31 2008-10-31
US16273709P 2009-03-24 2009-03-24

Publications (1)

Publication Number Publication Date
PL2326735T3 true PL2326735T3 (pl) 2017-04-28

Family

ID=41228200

Family Applications (2)

Application Number Title Priority Date Filing Date
PL12188429T PL2546365T3 (pl) 2008-09-03 2009-09-03 Zmiany genetyczne w dehydrogenazie izocytrynianowej i innych genach w glejaku złośliwym
PL09792198T PL2326735T3 (pl) 2008-09-03 2009-09-03 Zmiany genetyczne w dehydrogenazie izocytrynianowej i innych genach w glejaku złośliwym

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL12188429T PL2546365T3 (pl) 2008-09-03 2009-09-03 Zmiany genetyczne w dehydrogenazie izocytrynianowej i innych genach w glejaku złośliwym

Country Status (11)

Country Link
US (7) US8685660B2 (pl)
EP (4) EP3266879B1 (pl)
JP (3) JP5421374B2 (pl)
CN (1) CN102177251B (pl)
AU (1) AU2009288004B2 (pl)
CA (1) CA2736125C (pl)
DK (2) DK2546365T3 (pl)
ES (3) ES2609414T3 (pl)
MX (3) MX359574B (pl)
PL (2) PL2546365T3 (pl)
WO (1) WO2010028099A1 (pl)

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CN102177251B (zh) 2017-06-16
ES2608310T3 (es) 2017-04-07
US20170081730A1 (en) 2017-03-23
US10837064B2 (en) 2020-11-17
CA2736125A1 (en) 2010-03-11
EP2607498B1 (en) 2017-05-03
PL2546365T3 (pl) 2017-07-31
MX2011002409A (es) 2011-09-06
WO2010028099A1 (en) 2010-03-11
DK2326735T3 (en) 2017-01-16
JP6016755B2 (ja) 2016-10-26
JP2014110786A (ja) 2014-06-19
EP2326735B1 (en) 2016-11-16
CA2736125C (en) 2019-04-09
JP5421374B2 (ja) 2014-02-19
AU2009288004B2 (en) 2015-02-05
ES2755139T3 (es) 2020-04-21
US20180282821A1 (en) 2018-10-04
JP2016129517A (ja) 2016-07-21
US20140187764A1 (en) 2014-07-03
CN102177251A (zh) 2011-09-07
US20120202207A1 (en) 2012-08-09
EP3266879A1 (en) 2018-01-10
US9353418B2 (en) 2016-05-31
EP2326735A1 (en) 2011-06-01
US20190106752A1 (en) 2019-04-11
ES2609414T3 (es) 2017-04-20
EP3266879B1 (en) 2019-07-03
US20210317532A1 (en) 2021-10-14
DK2546365T3 (en) 2017-01-16
MX359574B (es) 2018-10-03
US10894987B2 (en) 2021-01-19
US10704108B2 (en) 2020-07-07
EP2546365B1 (en) 2016-11-09
AU2009288004A1 (en) 2010-03-11
EP2607498A1 (en) 2013-06-26
MX343226B (es) 2016-10-28
US20110229479A1 (en) 2011-09-22
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US8685660B2 (en) 2014-04-01

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