PL2173737T3 - Sposób modulowania receptora GPR119 sprzężonego z białkiem G i wybrane związki - Google Patents
Sposób modulowania receptora GPR119 sprzężonego z białkiem G i wybrane związkiInfo
- Publication number
- PL2173737T3 PL2173737T3 PL08781868T PL08781868T PL2173737T3 PL 2173737 T3 PL2173737 T3 PL 2173737T3 PL 08781868 T PL08781868 T PL 08781868T PL 08781868 T PL08781868 T PL 08781868T PL 2173737 T3 PL2173737 T3 PL 2173737T3
- Authority
- PL
- Poland
- Prior art keywords
- protein
- coupled receptor
- selected compounds
- modulating gpr119
- gpr119
- Prior art date
Links
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 title 1
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95016207P | 2007-07-17 | 2007-07-17 | |
EP08781868A EP2173737B1 (en) | 2007-07-17 | 2008-07-16 | Method for modulating gpr119 g protein-coupled receptor and selected compounds |
PCT/US2008/070103 WO2009012277A1 (en) | 2007-07-17 | 2008-07-16 | Method for modulating gpr119 g protein-coupled receptor and selected compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2173737T3 true PL2173737T3 (pl) | 2012-06-29 |
Family
ID=39864683
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL08781868T PL2173737T3 (pl) | 2007-07-17 | 2008-07-16 | Sposób modulowania receptora GPR119 sprzężonego z białkiem G i wybrane związki |
PL08781867T PL2170864T3 (pl) | 2007-07-17 | 2008-07-16 | Agoniści receptora gpr119 sprężonego z białkiem g - pirydon |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL08781867T PL2170864T3 (pl) | 2007-07-17 | 2008-07-16 | Agoniści receptora gpr119 sprężonego z białkiem g - pirydon |
Country Status (27)
Families Citing this family (51)
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AU2005310467B2 (en) * | 2004-12-01 | 2011-06-23 | Msd K.K. | Substituted pyridone derivative |
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ATE540945T1 (de) | 2007-07-17 | 2012-01-15 | Bristol Myers Squibb Co | Verfahren zur modulation des gpr119-g- proteingekoppelten rezeptors und ausgewählte verbindungen |
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TW201006821A (en) * | 2008-07-16 | 2010-02-16 | Bristol Myers Squibb Co | Pyridone and pyridazone analogues as GPR119 modulators |
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CA2730593A1 (en) * | 2008-07-16 | 2010-01-21 | Schering Corporation | Bicyclic heterocycle derivatives and use thereof as gpr119 modulators |
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US8293729B2 (en) | 2009-06-24 | 2012-10-23 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical composition and methods relating thereto |
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WO2011113947A1 (en) | 2010-03-18 | 2011-09-22 | Boehringer Ingelheim International Gmbh | Combination of a gpr119 agonist and the dpp-iv inhibitor linagliptin for use in the treatment of diabetes and related conditions |
JP2013523822A (ja) | 2010-04-08 | 2013-06-17 | ブリストル−マイヤーズ スクイブ カンパニー | Gpr119修飾因子としてのピリミジニルピペリジニルオキシピリジノ類似体 |
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