PL2161260T3 - Sposób semisyntezy dla wytwarzania 10-deacetylo-n-debenzoilo-paklitakselu - Google Patents

Sposób semisyntezy dla wytwarzania 10-deacetylo-n-debenzoilo-paklitakselu

Info

Publication number
PL2161260T3
PL2161260T3 PL09175976T PL09175976T PL2161260T3 PL 2161260 T3 PL2161260 T3 PL 2161260T3 PL 09175976 T PL09175976 T PL 09175976T PL 09175976 T PL09175976 T PL 09175976T PL 2161260 T3 PL2161260 T3 PL 2161260T3
Authority
PL
Poland
Prior art keywords
preparation
debenzoyl
deacetyl
paclitaxel
semisynthesis
Prior art date
Application number
PL09175976T
Other languages
English (en)
Inventor
Ezio Bombardelli
Bruno Gabetta
Andrea Gambini
Gabriele Fontana
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP04425752A external-priority patent/EP1647552A1/en
Priority claimed from EP05007888A external-priority patent/EP1712552A1/en
Application filed by Indena Spa filed Critical Indena Spa
Publication of PL2161260T3 publication Critical patent/PL2161260T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
PL09175976T 2004-10-08 2005-10-07 Sposób semisyntezy dla wytwarzania 10-deacetylo-n-debenzoilo-paklitakselu PL2161260T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US61684004P 2004-10-08 2004-10-08
EP04425752A EP1647552A1 (en) 2004-10-08 2004-10-08 Semisynthesis process for the preparation of 10-deacetyl-n-debenzoyl-paclitaxel
EP05007888A EP1712552A1 (en) 2005-04-11 2005-04-11 Semisynthesis process for the preparation of 10-deacetyl-n-debenzoyl-paclitaxel
EP09175976.1A EP2161260B1 (en) 2004-10-08 2005-10-07 Semisynthesis process for the preparation of 10 deacetyl-n-debenzoyl-paclitaxel
EP05798522A EP1797059B1 (en) 2004-10-08 2005-10-07 Semisynthesis process for the preparation of 10-deacetyl-n-debenzoyl-paclitaxel

Publications (1)

Publication Number Publication Date
PL2161260T3 true PL2161260T3 (pl) 2015-06-30

Family

ID=35445727

Family Applications (2)

Application Number Title Priority Date Filing Date
PL09175976T PL2161260T3 (pl) 2004-10-08 2005-10-07 Sposób semisyntezy dla wytwarzania 10-deacetylo-n-debenzoilo-paklitakselu
PL05798522T PL1797059T3 (pl) 2004-10-08 2005-10-07 Sposób semisyntezy do wytwarzania 10-deacetylo-N-debenzoilopaklitakselu

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL05798522T PL1797059T3 (pl) 2004-10-08 2005-10-07 Sposób semisyntezy do wytwarzania 10-deacetylo-N-debenzoilopaklitakselu

Country Status (21)

Country Link
US (3) US7446126B2 (pl)
EP (2) EP1797059B1 (pl)
JP (2) JP4971169B2 (pl)
KR (2) KR101216885B1 (pl)
CN (2) CN101704804B (pl)
AT (1) ATE451360T1 (pl)
AU (2) AU2005291357B2 (pl)
CA (2) CA2791783C (pl)
DE (1) DE602005018238D1 (pl)
DK (2) DK1797059T3 (pl)
ES (2) ES2531393T3 (pl)
HK (2) HK1108317A1 (pl)
IL (2) IL182396A (pl)
MX (1) MX2007004157A (pl)
NO (2) NO339631B1 (pl)
NZ (2) NZ585629A (pl)
PL (2) PL2161260T3 (pl)
PT (2) PT2161260E (pl)
RU (2) RU2510395C2 (pl)
SI (2) SI2161260T1 (pl)
WO (1) WO2006037653A1 (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
ITMI20050614A1 (it) * 2005-04-12 2006-10-13 Indena Spa Processo per la purificazione della 10-deacetilbaccatina iii dalla 10-deacetil-2-debenzoil-2-pentenoilbaccatina iii
JP2009533330A (ja) * 2006-03-21 2009-09-17 ドクター レディズ ラボラトリーズ リミテッド ドセタキセルの多形体およびプロセス
PL210984B1 (pl) * 2006-10-31 2012-03-30 Inst Farmaceutyczny Sposób wytwarzania docetakselu
PL388144A1 (pl) 2009-05-29 2010-12-06 Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie
KR101149600B1 (ko) * 2009-12-31 2012-05-29 주식회사 삼양제넥스바이오 고순도 무수결정형 도세탁셀 제조방법
WO2011139899A2 (en) 2010-05-03 2011-11-10 Teikoku Pharma Usa, Inc. Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
EP2959131B1 (en) 2013-02-19 2019-05-29 United Technologies Corporation Composite attachment structure with 3d weave
CN108822062B (zh) * 2018-09-07 2020-08-28 无锡紫杉药业有限公司 一种多西他赛的精制方法
WO2020249507A1 (en) 2019-06-11 2020-12-17 Indena S.P.A. Anhydrous crystalline form of cabazitaxel, a process for its preparation and pharmaceutical compositions containing it

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
FR2696458B1 (fr) 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2718963B1 (fr) * 1994-04-25 1996-05-24 Rhone Poulenc Rorer Sa Nouvelle composition pharmaceutique à base de taxoïdes.
CA2170661A1 (en) * 1995-03-22 1996-09-23 John K. Thottathil Novel methods for the preparation of taxanes using oaxzolidine intermediates
IT1308636B1 (it) * 1999-03-02 2002-01-09 Indena Spa Procedimento per la preparazione di tassani da 10-desacetilbaccatinaiii.
IT1318678B1 (it) * 2000-08-10 2003-08-27 Indena Spa Procedimento per la preparazione di derivati della baccatina iii.
IT1320107B1 (it) * 2000-11-28 2003-11-18 Indena Spa Procedimento per la preparazione di derivati tassanici.
US6881852B2 (en) * 2002-02-05 2005-04-19 Dabur India Limited Process of purification of paclitaxel and docetaxel
ITMI20020782A1 (it) 2002-04-12 2003-10-13 Indena Spa Processo semisintetico per la preparazione di n-debenzoilpaclitaxel
PE20050206A1 (es) * 2003-05-26 2005-03-26 Schering Ag Composicion farmaceutica que contiene un inhibidor de histona deacetilasa
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel

Also Published As

Publication number Publication date
US7446126B2 (en) 2008-11-04
PT1797059E (pt) 2009-12-21
RU2009143794A (ru) 2011-06-10
JP5593342B2 (ja) 2014-09-24
IL208290A0 (en) 2010-12-30
RU2007112775A (ru) 2008-10-10
KR20070062533A (ko) 2007-06-15
SI2161260T1 (sl) 2015-05-29
NZ585629A (en) 2012-01-12
BRPI0516566A (pt) 2008-09-09
HK1140490A1 (en) 2010-10-15
WO2006037653A1 (en) 2006-04-13
IL182396A0 (en) 2007-07-24
EP1797059B1 (en) 2009-12-09
EP2161260A1 (en) 2010-03-10
IL208290A (en) 2012-03-29
SI1797059T1 (sl) 2010-02-26
DK1797059T3 (da) 2010-04-06
NZ554344A (en) 2010-09-30
EP2161260B1 (en) 2015-01-21
KR101216885B1 (ko) 2012-12-28
KR101146839B1 (ko) 2012-05-16
CA2582545C (en) 2013-01-08
NO339631B1 (no) 2017-01-16
JP2008515840A (ja) 2008-05-15
AU2005291357B2 (en) 2011-04-14
HK1108317A1 (en) 2008-05-02
MX2007004157A (es) 2007-06-20
CA2791783C (en) 2014-12-09
NO340930B1 (no) 2017-07-17
KR20090038496A (ko) 2009-04-20
PT2161260E (pt) 2015-03-02
EP1797059A1 (en) 2007-06-20
RU2384578C2 (ru) 2010-03-20
CA2582545A1 (en) 2006-04-13
ES2531393T3 (es) 2015-03-13
CN101048395A (zh) 2007-10-03
AU2011201419A1 (en) 2011-04-14
JP2012136544A (ja) 2012-07-19
CN100584836C (zh) 2010-01-27
DK2161260T3 (da) 2015-03-16
US20080200700A1 (en) 2008-08-21
ATE451360T1 (de) 2009-12-15
RU2510395C2 (ru) 2014-03-27
CN101704804B (zh) 2015-03-18
US20060079571A1 (en) 2006-04-13
NO20071835L (no) 2007-05-07
IL182396A (en) 2011-12-29
CA2791783A1 (en) 2006-04-13
AU2011201419B2 (en) 2012-01-19
CN101704804A (zh) 2010-05-12
DE602005018238D1 (de) 2010-01-21
PL1797059T3 (pl) 2010-05-31
US8318957B2 (en) 2012-11-27
NO20161147A1 (no) 2007-05-07
US20080167369A1 (en) 2008-07-10
ES2333738T3 (es) 2010-02-26
AU2005291357A1 (en) 2006-04-13
JP4971169B2 (ja) 2012-07-11

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