|
US8124759B2
(en)
*
|
2007-05-09 |
2012-02-28 |
Abbott Laboratories |
Inhibitors of protein kinases
|
|
US8242085B2
(en)
|
2007-05-10 |
2012-08-14 |
Biocryst Pharmaceuticals, Inc. |
Tetrahydrofuro [3,4-D] dioxolane compounds for use in the treatment of viral infections and cancer
|
|
TW200942243A
(en)
*
|
2008-03-05 |
2009-10-16 |
Biocryst Pharm Inc |
Antiviral therapeutic agents
|
|
US20090247750A1
(en)
*
|
2008-03-28 |
2009-10-01 |
Biocryst Pharmaceuticals, Inc. |
Process for preparing nucleoside analogs
|
|
HUE038946T2
(hu)
|
2008-04-23 |
2018-12-28 |
Gilead Sciences Inc |
1'-szubsztituált carba-nukleozid analógok antivirális kezelésre
|
|
WO2010002877A2
(en)
*
|
2008-07-03 |
2010-01-07 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
|
KR101834707B1
(ko)
|
2009-02-10 |
2018-03-05 |
길리애드 사이언시즈, 인코포레이티드 |
항바이러스 치료를 위한 카르바-뉴클레오시드 유사체
|
|
JP5767643B2
(ja)
|
2009-09-21 |
2015-08-19 |
ギリード・サイエンシズ・インコーポレーテッド |
1’−置換カルバヌクレオシド類似体の調製のためのプロセスおよび中間体
|
|
BR112012006261B1
(pt)
|
2009-09-21 |
2021-12-21 |
Gilead Sciences, Inc |
Compostos análogos de 2'-flúor substituído carbanucleosídeo, composto útil para a preparação do mesmo, composição farmacêutica e uso dos compostos análogos de 2'-flúor substituído carbanucleosídeo
|
|
US8455451B2
(en)
|
2009-09-21 |
2013-06-04 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
WO2011123493A1
(en)
|
2010-03-31 |
2011-10-06 |
Bristol-Myers Squibb Company |
Substituted pyrrolotriazines as protein kinase inhibitors
|
|
TW201201815A
(en)
|
2010-05-28 |
2012-01-16 |
Gilead Sciences Inc |
1'-substituted-carba-nucleoside prodrugs for antiviral treatment
|
|
KR101995598B1
(ko)
|
2010-07-19 |
2019-07-02 |
길리애드 사이언시즈, 인코포레이티드 |
부분입체 이성질성으로 순수한 포스포라미데이트 전구약물의 제조 방법
|
|
PE20130400A1
(es)
|
2010-07-22 |
2013-04-10 |
Gilead Sciences Inc |
Metodos y compuestos para tratar infecciones virales por paramyxoviridae
|
|
TW201305185A
(zh)
*
|
2010-09-13 |
2013-02-01 |
Gilead Sciences Inc |
用於抗病毒治療之2’-氟取代之碳-核苷類似物
|
|
SG188223A1
(en)
|
2010-09-20 |
2013-04-30 |
Gilead Sciences Inc |
2' -fluoro substituted carba-nucleoside analogs for antiviral treatment
|
|
CA2812962C
(en)
|
2010-09-22 |
2020-03-31 |
Alios Biopharma, Inc. |
Azido nucleosides and nucleotide analogs
|
|
WO2012088266A2
(en)
|
2010-12-22 |
2012-06-28 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
|
|
US8877733B2
(en)
|
2011-04-13 |
2014-11-04 |
Gilead Sciences, Inc. |
1′-substituted pyrimidine N-nucleoside analogs for antiviral treatment
|
|
PE20140570A1
(es)
|
2011-07-01 |
2014-04-28 |
Bayer Ip Gmbh |
Pirrolotriazinas sustituidas con hidroximetilarilo y sus usos
|
|
AR088441A1
(es)
|
2011-09-12 |
2014-06-11 |
Idenix Pharmaceuticals Inc |
Compuestos de carboniloximetilfosforamidato sustituido y composiciones farmaceuticas para el tratamiento de infecciones virales
|
|
CA2752008A1
(en)
|
2011-09-13 |
2013-03-13 |
Universite De Montreal |
Combination therapy using ribavirin as elf4e inhibitor
|
|
EP2794627B1
(en)
|
2011-12-22 |
2018-09-26 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
EA201791916A1
(ru)
|
2012-03-13 |
2018-07-31 |
Джилид Сайэнс, Инк. |
2'-замещенные карбануклеозидные аналоги для противовирусного лечения
|
|
US9441007B2
(en)
|
2012-03-21 |
2016-09-13 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
USRE48171E1
(en)
|
2012-03-21 |
2020-08-25 |
Janssen Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
AR090699A1
(es)
|
2012-04-18 |
2014-12-03 |
Biocryst Pharm Inc |
Compuestos inhibidores de la actividad de la arn polimerasa viral
|
|
SI2861595T1
(sl)
|
2012-06-13 |
2017-04-26 |
Incyte Holdings Corporation |
Substituirane triciklične spojine kot inhibitorji fgfr
|
|
US9388185B2
(en)
|
2012-08-10 |
2016-07-12 |
Incyte Holdings Corporation |
Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
|
|
HK1212235A1
(en)
*
|
2012-11-16 |
2016-06-10 |
Biocryst Pharmaceuticals, Inc. |
Antiviral azasugar-containing nucleosides
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
LT2986610T
(lt)
|
2013-04-19 |
2018-04-10 |
Incyte Holdings Corporation |
Bicikliniai heterociklai, kaip fgfr inhibitoriai
|
|
AU2014331863C1
(en)
|
2013-10-11 |
2019-05-16 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
|
UA119050C2
(uk)
|
2013-11-11 |
2019-04-25 |
Ґілеад Саєнсиз, Інк. |
ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ
|
|
WO2015143712A1
(en)
|
2014-03-28 |
2015-10-01 |
Merck Sharp & Dohme Corp. |
4'-substituted nucleoside reverse transcriptase inhibitors
|
|
TWI678369B
(zh)
|
2014-07-28 |
2019-12-01 |
美商基利科學股份有限公司 |
用於治療呼吸道合胞病毒感染之噻吩並[3,2-d]嘧啶、呋喃並[3,2-d]嘧啶及吡咯並[3,2-d]嘧啶化合物類
|
|
TWI673283B
(zh)
|
2014-08-21 |
2019-10-01 |
美商基利科學股份有限公司 |
2’-氯胺基嘧啶酮及嘧啶二酮核苷類
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
ES2749679T3
(es)
|
2014-10-22 |
2020-03-23 |
Bristol Myers Squibb Co |
Compuestos de pirrolotriazina amina sustituidos como inhibidores de PI3k
|
|
US10214537B2
(en)
|
2014-10-22 |
2019-02-26 |
Bristol-Myers Squibb Company |
Bicyclic heteroaryl amine compounds
|
|
TWI698444B
(zh)
*
|
2014-10-29 |
2020-07-11 |
美商基利科學股份有限公司 |
製備核糖苷的方法
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
WO2016134294A1
(en)
|
2015-02-20 |
2016-08-25 |
Incyte Corporation |
Bicyclic heterocycles as fgfr4 inhibitors
|
|
SG10201913036RA
(en)
|
2015-02-20 |
2020-02-27 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
HK1247829A1
(zh)
|
2015-03-06 |
2018-10-05 |
Atea Pharmaceuticals, Inc. |
用於治疗HCV的β-D-2'-脱氧-2'Α-氟-2'-β-C-取代-2-改性N6-取代的嘌呤核苷酸
|
|
CN104876935B
(zh)
*
|
2015-05-18 |
2017-04-19 |
南方医科大学 |
2‑氨基吡咯并[1,2‑f][1,2,4]三嗪类化合物、合成方法及应用
|
|
PT3349758T
(pt)
|
2015-09-16 |
2022-07-13 |
Gilead Sciences Inc |
Métodos para o tratamento de infeções pelo vírus arenaviridae
|
|
US10953029B2
(en)
|
2015-09-23 |
2021-03-23 |
Merck Sharp & Dohme Corp. |
4′-Substituted nucleoside reverse transcriptase inhibitors and preparations thereof
|
|
CN109071467B
(zh)
|
2016-03-09 |
2023-04-04 |
艾丽奥斯生物制药有限公司 |
无环抗病毒药
|
|
WO2017155949A1
(en)
|
2016-03-09 |
2017-09-14 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Methods and kits for use in preventing and treating vulvovaginal candidiasis
|
|
JP7034084B2
(ja)
|
2016-03-28 |
2022-03-11 |
インサイト・コーポレイション |
Tam阻害剤としてのピロロトリアジン化合物
|
|
LU100724B1
(en)
|
2016-07-14 |
2018-07-31 |
Atea Pharmaceuticals Inc |
Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
|
|
EP3512863B1
(en)
|
2016-09-07 |
2021-12-08 |
ATEA Pharmaceuticals, Inc. |
2'-substituted-n6-substituted purine nucleotides for rna virus treatment
|
|
CA3040540A1
(en)
|
2016-11-10 |
2018-05-17 |
Oyagen, Inc. |
Methods of treating and inhibiting ebola virus infection
|
|
EP4450129A3
(en)
|
2017-02-01 |
2025-03-19 |
ATEA Pharmaceuticals, Inc. |
Nucleotide hemi-sulfate salt for the treatment of hepatitis c virus
|
|
CN110869028B
(zh)
|
2017-03-14 |
2023-01-20 |
吉利德科学公司 |
治疗猫冠状病毒感染的方法
|
|
KR20190141747A
(ko)
|
2017-05-01 |
2019-12-24 |
길리애드 사이언시즈, 인코포레이티드 |
(S)-2-에틸부틸 2-(((S)-(((2R,3S,4R,5R)-5-(4-아미노피롤로[2,1-f] [1,2,4]트리아진-7-일)-5-시아노-3,4-디히드록시테트라히드로푸란-2-일)메톡시)(페녹시) 포스포릴)아미노)프로파노에이트의 결정질 형태
|
|
CN107056775A
(zh)
*
|
2017-05-24 |
2017-08-18 |
佛山科学技术学院 |
丙型肝炎病毒ns5b聚合酶抑制剂
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
US10675296B2
(en)
|
2017-07-11 |
2020-06-09 |
Gilead Sciences, Inc. |
Compositions comprising an RNA polymerase inhibitor and cyclodextrin for treating viral infections
|
|
US11040975B2
(en)
|
2017-12-08 |
2021-06-22 |
Merck Sharp & Dohme Corp. |
Carbocyclic nucleoside reverse transcriptase inhibitors
|
|
TW202012001A
(zh)
|
2018-04-10 |
2020-04-01 |
美商亞堤製藥公司 |
C型肝炎病毒(hcv)感染硬化之患者的治療
|
|
PL3788047T3
(pl)
|
2018-05-04 |
2025-04-14 |
Incyte Corporation |
Stałe postacie inhibitora fgfr i sposoby ich otrzymywania
|
|
KR20210018264A
(ko)
|
2018-05-04 |
2021-02-17 |
인사이트 코포레이션 |
Fgfr 억제제의 염
|
|
EP3894395A2
(en)
|
2018-12-12 |
2021-10-20 |
Janssen BioPharma, Inc. |
Cyclopentyl nucleoside analogs as anti-virals
|
|
WO2020185532A1
(en)
|
2019-03-08 |
2020-09-17 |
Incyte Corporation |
Methods of treating cancer with an fgfr inhibitor
|
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2021067374A1
(en)
|
2019-10-01 |
2021-04-08 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
CR20220169A
(es)
|
2019-10-14 |
2022-10-27 |
Incyte Corp |
Heterociclos bicíclicos como inhibidores de fgfr
|
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
JP7720840B2
(ja)
|
2019-12-04 |
2025-08-08 |
インサイト・コーポレイション |
Fgfr阻害剤としての三環式複素環
|
|
AU2020395185A1
(en)
|
2019-12-04 |
2022-06-02 |
Incyte Corporation |
Derivatives of an FGFR inhibitor
|
|
WO2021146424A1
(en)
|
2020-01-15 |
2021-07-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
CN118766947A
(zh)
|
2020-01-27 |
2024-10-15 |
吉利德科学公司 |
用于治疗SARS CoV-2感染的方法
|
|
WO2021158248A1
(en)
|
2020-02-04 |
2021-08-12 |
Oyagen, Inc. |
Method for treating coronavirus infections
|
|
CN113214262B
(zh)
*
|
2020-02-05 |
2023-07-07 |
华创合成制药股份有限公司 |
一种含有胍基的化合物及其制备方法和用途
|
|
CA3171648A1
(en)
|
2020-02-18 |
2021-08-26 |
Gilead Sciences, Inc. |
Antiviral compounds
|
|
TWI775313B
(zh)
|
2020-02-18 |
2022-08-21 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
TWI883391B
(zh)
|
2020-02-18 |
2025-05-11 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
TWI791193B
(zh)
|
2020-02-18 |
2023-02-01 |
美商基利科學股份有限公司 |
抗病毒化合物
|
|
US10874687B1
(en)
|
2020-02-27 |
2020-12-29 |
Atea Pharmaceuticals, Inc. |
Highly active compounds against COVID-19
|
|
CA3169340A1
(en)
|
2020-03-12 |
2021-09-16 |
Pavel R. Badalov |
Methods of preparing 1'-cyano nucleosides
|
|
JP7482250B2
(ja)
|
2020-04-06 |
2024-05-13 |
ギリアード サイエンシーズ, インコーポレイテッド |
1’-シアノ置換カルバヌクレオシド類似体の吸入製剤
|
|
PL4157272T3
(pl)
|
2020-05-29 |
2025-10-20 |
Gilead Sciences, Inc. |
Remdesiwir do leczenia zakażeń wirusowych
|
|
JP2023531524A
(ja)
|
2020-06-24 |
2023-07-24 |
ギリアード サイエンシーズ, インコーポレイテッド |
1’-シアノヌクレオシド類似体及びその使用
|
|
JP2023542455A
(ja)
*
|
2020-07-14 |
2023-10-10 |
スーチュワン ユニバーシティ |
3-デオキシ-2-ケトアルドン酸窒素含有誘導体、その製造方法及びその使用
|
|
LT4204421T
(lt)
|
2020-08-27 |
2024-06-25 |
Gilead Sciences, Inc. |
Virusinių infekcijų gydymui skirti junginiai ir būdai
|
|
TW202304459A
(zh)
|
2021-04-12 |
2023-02-01 |
美商英塞特公司 |
包含fgfr抑制劑及nectin-4靶向劑之組合療法
|
|
PL4323362T3
(pl)
|
2021-04-16 |
2025-08-18 |
Gilead Sciences, Inc. |
Sposoby wytwarzania karbanukleozydów z zastosowaniem amidów
|
|
EP4352060A1
(en)
|
2021-06-09 |
2024-04-17 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
US11939331B2
(en)
|
2021-06-09 |
2024-03-26 |
Incyte Corporation |
Tricyclic heterocycles as FGFR inhibitors
|
|
CN117500494A
(zh)
|
2021-06-17 |
2024-02-02 |
阿堤亚制药公司 |
有利的抗hcv联合疗法
|
|
AU2022328698B2
(en)
|
2021-08-18 |
2025-02-20 |
Gilead Sciences, Inc. |
Phospholipid compounds and methods of making and using the same
|
|
CN118119624A
(zh)
*
|
2021-08-20 |
2024-05-31 |
盐野义制药株式会社 |
具有病毒增殖抑制作用的核苷衍生物及其前药
|
|
US20230295172A1
(en)
|
2022-03-02 |
2023-09-21 |
Gilead Sciences, Inc. |
Compounds and methods for treatment of viral infections
|
|
US12357577B1
(en)
|
2024-02-02 |
2025-07-15 |
Gilead Sciences, Inc. |
Pharmaceutical formulations and uses thereof
|