PL2059513T3 - Sposób wytwarzania pochodnych 1,2,4-oksadiazolowych kwasu benzoesowego - Google Patents

Sposób wytwarzania pochodnych 1,2,4-oksadiazolowych kwasu benzoesowego

Info

Publication number
PL2059513T3
PL2059513T3 PL07837899T PL07837899T PL2059513T3 PL 2059513 T3 PL2059513 T3 PL 2059513T3 PL 07837899 T PL07837899 T PL 07837899T PL 07837899 T PL07837899 T PL 07837899T PL 2059513 T3 PL2059513 T3 PL 2059513T3
Authority
PL
Poland
Prior art keywords
preparation
benzoic acids
oxadiazole benzoic
oxadiazole
acids
Prior art date
Application number
PL07837899T
Other languages
English (en)
Polish (pl)
Inventor
Neil G Almstead
Peter Seongwoo Hwang
Seemon Pines
Young-Choon Moon
James J Takasugi
Original Assignee
Ptc Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ptc Therapeutics Inc filed Critical Ptc Therapeutics Inc
Publication of PL2059513T3 publication Critical patent/PL2059513T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL07837899T 2006-09-08 2007-09-06 Sposób wytwarzania pochodnych 1,2,4-oksadiazolowych kwasu benzoesowego PL2059513T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US84359506P 2006-09-08 2006-09-08
EP07837899A EP2059513B1 (en) 2006-09-08 2007-09-06 Process for the preparation of 1,2,4-oxadiazole benzoic acids
PCT/US2007/019561 WO2008030570A1 (en) 2006-09-08 2007-09-06 Processes for the preparation of 1,2,4-oxadiazole benzoic acids

Publications (1)

Publication Number Publication Date
PL2059513T3 true PL2059513T3 (pl) 2013-06-28

Family

ID=38935880

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07837899T PL2059513T3 (pl) 2006-09-08 2007-09-06 Sposób wytwarzania pochodnych 1,2,4-oksadiazolowych kwasu benzoesowego

Country Status (24)

Country Link
US (2) US7678922B2 (enExample)
EP (1) EP2059513B1 (enExample)
JP (2) JP5955494B2 (enExample)
KR (1) KR101466368B1 (enExample)
CN (1) CN101535284B (enExample)
AR (3) AR062715A1 (enExample)
AU (1) AU2007292915B2 (enExample)
BR (1) BRPI0716996B8 (enExample)
CA (2) CA2662749C (enExample)
CL (1) CL2007002606A1 (enExample)
DK (1) DK2059513T3 (enExample)
ES (1) ES2404348T3 (enExample)
IL (1) IL197445A (enExample)
MX (1) MX2009002439A (enExample)
MY (1) MY148598A (enExample)
NZ (2) NZ598012A (enExample)
PE (2) PE20080771A1 (enExample)
PL (1) PL2059513T3 (enExample)
PT (1) PT2059513E (enExample)
RU (1) RU2495030C2 (enExample)
TW (1) TWI482761B (enExample)
UA (1) UA99265C2 (enExample)
WO (1) WO2008030570A1 (enExample)
ZA (1) ZA200901782B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2910551T3 (pl) 2003-04-11 2017-09-29 Ptc Therapeutics, Inc. Związki kwasu 1,2,4-oksadiazolobenzoesowego i ich zastosowanie do supresji mutacji nonsensownych i leczenia choroby
PT2402002T (pt) 2005-04-08 2018-10-08 Ptc Therapeutics Inc Composições de 1,2,4-oxadiazole oralmente activo para terapia de supressão de mutações nonsense
CA2647903C (en) 2006-03-30 2016-12-13 Ptc Therapeutics, Inc. Methods for the production of functional protein from dna having a nonsense mutation and the treatment of disorders associated therewith
WO2008030570A1 (en) * 2006-09-08 2008-03-13 Ptc Therapeutics, Inc. Processes for the preparation of 1,2,4-oxadiazole benzoic acids
EP2068871B1 (en) 2006-09-25 2013-12-25 PTC Therapeutics, Inc. Hydroxylated 1,2,4-oxadiazole benzoic acid compounds, compositions thereof and the use for nonsense suppression
SI2076501T1 (sl) * 2006-09-25 2016-05-31 Ptc Therapeutics, Inc. Kristalinične oblike 3-(5-(2-florofenil)-1,2,4) oksadiazol-3-il)-benzojske kisline
ES2538359T3 (es) 2006-10-12 2015-06-19 Ptc Therapeutics, Inc. Métodos para administrar un 1,2,4-oxadiazol activo por vía oral para terapia de supresión de mutación sin sentido
CN101714009A (zh) * 2009-05-14 2010-05-26 翁印嵩 集成通用电话功能的计算机
ES2610362T3 (es) 2011-01-25 2017-04-27 Viviabiotech, S.L. Derivados de 1,2,4-oxadiazol como fármacos moduladores del receptor para el péptido glp-1
UA114915C2 (uk) 2012-07-02 2017-08-28 Монсанто Текнолоджи Ллс Спосіб одержання 3,5-дизаміщених 1,2,4-оксадіазолів (варіанти)
TWI695717B (zh) 2014-03-06 2020-06-11 美商 Ptc 治療公司 １,２,４-二唑苯甲酸之鹽及醫藥組合物
CN105461650B (zh) * 2014-09-12 2018-04-13 杭州普晒医药科技有限公司 一种噁二唑化合物的溶剂化物及其制备方法
CN106316885B (zh) * 2015-07-03 2019-02-12 普济生物科技（台州）有限公司 一种3-[5-(2-氟苯基)-1,2,4-噁二唑-3-基]苯甲酸的制备方法
MX2018005361A (es) 2015-10-30 2018-06-07 Ptc Therapeutics Inc Metodos para tratar epilepsia.
TW201808922A (zh) 2016-06-20 2018-03-16 台灣神隆股份有限公司 製備阿塔魯仁及其中間體的方法
US12268669B2 (en) 2018-12-20 2025-04-08 Pfizer Inc. Pharmaceutical compositions and methods comprising a combination of a benzoxazole transthyretin stabilizer and an additional therapeutic agent
EA202192767A1 (ru) 2019-04-10 2021-12-29 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Способ лечения опосредуемой нонсенс-мутацией мышечной дистрофии дюшенна у педиатрических пациентов
WO2022112919A1 (en) 2020-11-25 2022-06-02 Pfizer Inc. (aza)benzothiazolyl substituted pyrazole compounds
CN113045510B (zh) * 2021-03-31 2022-05-27 北京大学生命科学华东产业研究院 一种阿塔鲁伦的制备方法
CN114920667B (zh) * 2022-06-30 2024-06-21 湖南大学 一种阿塔鲁伦酯的电化学制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2801509A1 (de) * 1978-01-12 1979-07-19 Schering Ag 1,2,4-oxadiazolderivate, verfahren zur herstellung dieser verbindungen sowie diese enthaltende selektive herbizide mittel
DE3905242A1 (de) * 1989-02-21 1990-08-23 Basf Ag Verfahren zur herstellung von phenyloxdiazolylanilinen
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
DE4425794A1 (de) * 1994-07-21 1996-01-25 Basf Ag Nitrofarbstoffe
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
CA2449544A1 (en) * 2001-06-08 2002-12-19 Cytovia, Inc. Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs
MY151199A (en) * 2001-11-02 2014-04-30 Rigel Pharmaceuticals Inc Substituted diphenyl heterocycles useful for treating hcv infection
US20040132726A1 (en) * 2002-08-09 2004-07-08 Astrazeneca Ab And Nps Pharmaceuticals, Inc. New compounds
GB0303503D0 (en) 2003-02-14 2003-03-19 Novartis Ag Organic compounds
PL2910551T3 (pl) * 2003-04-11 2017-09-29 Ptc Therapeutics, Inc. Związki kwasu 1,2,4-oksadiazolobenzoesowego i ich zastosowanie do supresji mutacji nonsensownych i leczenia choroby
US20050075375A1 (en) * 2003-05-14 2005-04-07 Anadys Pharmaceuticals, Inc. Heterocyclic compounds for treating hepatitis C virus
PT2402002T (pt) * 2005-04-08 2018-10-08 Ptc Therapeutics Inc Composições de 1,2,4-oxadiazole oralmente activo para terapia de supressão de mutações nonsense
WO2008030570A1 (en) * 2006-09-08 2008-03-13 Ptc Therapeutics, Inc. Processes for the preparation of 1,2,4-oxadiazole benzoic acids

Also Published As

Publication number Publication date
WO2008030570A1 (en) 2008-03-13
UA99265C2 (ru) 2012-08-10
TWI482761B (zh) 2015-05-01
DK2059513T3 (da) 2013-05-06
ZA200901782B (en) 2010-06-30
AR062715A1 (es) 2008-11-26
CA2662749A1 (en) 2008-03-13
US8367841B2 (en) 2013-02-05
JP2010502715A (ja) 2010-01-28
CA2842625C (en) 2016-07-12
RU2495030C2 (ru) 2013-10-10
AR118922A2 (es) 2021-11-10
EP2059513B1 (en) 2013-01-23
EP2059513A1 (en) 2009-05-20
PT2059513E (pt) 2013-04-30
BRPI0716996A2 (pt) 2013-10-08
CA2842625A1 (en) 2008-03-13
IL197445A (en) 2014-01-30
AU2007292915A1 (en) 2008-03-13
TW200823180A (en) 2008-06-01
PE20080771A1 (es) 2008-06-13
ES2404348T3 (es) 2013-05-27
AU2007292915B2 (en) 2012-07-26
AR107474A2 (es) 2018-05-02
BRPI0716996B1 (pt) 2021-02-09
US20080139818A1 (en) 2008-06-12
NZ598012A (en) 2013-08-30
JP5955494B2 (ja) 2016-07-20
CL2007002606A1 (es) 2008-04-18
MY148598A (en) 2013-05-15
US7678922B2 (en) 2010-03-16
CN101535284A (zh) 2009-09-16
US20100063297A1 (en) 2010-03-11
KR101466368B1 (ko) 2014-11-27
MX2009002439A (es) 2009-03-27
HK1134094A1 (en) 2010-04-16
NZ575511A (en) 2012-02-24
RU2009113019A (ru) 2010-10-20
CA2662749C (en) 2015-01-20
PE20120669A1 (es) 2012-06-01
JP2014193896A (ja) 2014-10-09
CN101535284B (zh) 2014-12-10
BRPI0716996B8 (pt) 2021-05-25
KR20090054464A (ko) 2009-05-29
IL197445A0 (en) 2009-12-24

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