PL2059513T3 - Sposób wytwarzania pochodnych 1,2,4-oksadiazolowych kwasu benzoesowego - Google Patents

Sposób wytwarzania pochodnych 1,2,4-oksadiazolowych kwasu benzoesowego

Info

Publication number
PL2059513T3
PL2059513T3 PL07837899T PL07837899T PL2059513T3 PL 2059513 T3 PL2059513 T3 PL 2059513T3 PL 07837899 T PL07837899 T PL 07837899T PL 07837899 T PL07837899 T PL 07837899T PL 2059513 T3 PL2059513 T3 PL 2059513T3
Authority
PL
Poland
Prior art keywords
preparation
benzoic acids
oxadiazole benzoic
oxadiazole
acids
Prior art date
Application number
PL07837899T
Other languages
English (en)
Inventor
Neil G Almstead
Peter Seongwoo Hwang
Seemon Pines
Young-Choon Moon
James J Takasugi
Original Assignee
Ptc Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ptc Therapeutics Inc filed Critical Ptc Therapeutics Inc
Publication of PL2059513T3 publication Critical patent/PL2059513T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL07837899T 2006-09-08 2007-09-06 Sposób wytwarzania pochodnych 1,2,4-oksadiazolowych kwasu benzoesowego PL2059513T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US84359506P 2006-09-08 2006-09-08
PCT/US2007/019561 WO2008030570A1 (en) 2006-09-08 2007-09-06 Processes for the preparation of 1,2,4-oxadiazole benzoic acids
EP07837899A EP2059513B1 (en) 2006-09-08 2007-09-06 Process for the preparation of 1,2,4-oxadiazole benzoic acids

Publications (1)

Publication Number Publication Date
PL2059513T3 true PL2059513T3 (pl) 2013-06-28

Family

ID=38935880

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07837899T PL2059513T3 (pl) 2006-09-08 2007-09-06 Sposób wytwarzania pochodnych 1,2,4-oksadiazolowych kwasu benzoesowego

Country Status (24)

Country Link
US (2) US7678922B2 (pl)
EP (1) EP2059513B1 (pl)
JP (2) JP5955494B2 (pl)
KR (1) KR101466368B1 (pl)
CN (1) CN101535284B (pl)
AR (3) AR062715A1 (pl)
AU (1) AU2007292915B2 (pl)
BR (1) BRPI0716996B8 (pl)
CA (2) CA2842625C (pl)
CL (1) CL2007002606A1 (pl)
DK (1) DK2059513T3 (pl)
ES (1) ES2404348T3 (pl)
IL (1) IL197445A (pl)
MX (1) MX2009002439A (pl)
MY (1) MY148598A (pl)
NZ (2) NZ598012A (pl)
PE (2) PE20120669A1 (pl)
PL (1) PL2059513T3 (pl)
PT (1) PT2059513E (pl)
RU (1) RU2495030C2 (pl)
TW (1) TWI482761B (pl)
UA (1) UA99265C2 (pl)
WO (1) WO2008030570A1 (pl)
ZA (1) ZA200901782B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3345895B1 (en) * 2003-04-11 2019-12-04 PTC Therapeutics, Inc. 1,2,4-oxadiazole benzoic acid compound and its use for nonsense suppression and the treatment of disease
CA2603402C (en) 2005-04-08 2017-10-31 Ptc Therapeutics, Inc. Compositions of an orally active 1,2,4-oxadiazole for nonsense mutation suppression therapy
RU2462246C2 (ru) * 2006-03-30 2012-09-27 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Способы получения функционального белка из днк, имеющей нонсенс-мутацию, и лечения нарушений, ассоциированных с ней
ES2404348T3 (es) * 2006-09-08 2013-05-27 Ptc Therapeutics, Inc. Procedimiento para la preparación de ácidos 1, 2, 4-oxadiazol-benzoicos
EP2068871B1 (en) 2006-09-25 2013-12-25 PTC Therapeutics, Inc. Hydroxylated 1,2,4-oxadiazole benzoic acid compounds, compositions thereof and the use for nonsense suppression
CL2007002743A1 (es) * 2006-09-25 2008-07-11 Pct Therapeutics Inc Soc Organ Forma cristalina del acido 3-[5-(2-fluorofenil)-[1,2,4]oxadiazol-3-il]-benzoico; composicion farmaceutica que comprende a dicha forma cristalina; y su uso para modular la terminacion prematura de traslado o decaimiento de marn, tales como carcicoma.
SI2073805T1 (sl) 2006-10-12 2015-10-30 Ptc Therapeutics, Inc. Postopki za odmerjanje peroralno aktivnega 1,2,4-oksadiazola za zdravljenje supresije nesmiselnih mutacij
CN101714009A (zh) * 2009-05-14 2010-05-26 翁印嵩 集成通用电话功能的计算机
EP2668951B9 (en) 2011-01-25 2017-03-15 Viviabiotech, S.L. 1,2,4-oxadiazole derivatives as drugs modulating the glp-1 peptide receptor
AU2013286860B2 (en) 2012-07-02 2017-10-26 Monsanto Technology Llc Processes for the preparation of 3,5-disubstituted-1,2,4-oxadiazoles
JP6946001B2 (ja) 2014-03-06 2021-10-06 ピーティーシー セラピューティクス， インコーポレイテッド 薬学的組成物、および１，２，４−オキサジアゾール安息香酸の塩
CN105461650B (zh) * 2014-09-12 2018-04-13 杭州普晒医药科技有限公司 一种噁二唑化合物的溶剂化物及其制备方法
CN106316885B (zh) * 2015-07-03 2019-02-12 普济生物科技（台州）有限公司 一种3-[5-(2-氟苯基)-1,2,4-噁二唑-3-基]苯甲酸的制备方法
HK1251965A1 (zh) 2015-10-30 2019-05-10 Ptc医疗公司 用於治疗癫痫的方法
TW201808922A (zh) 2016-06-20 2018-03-16 台灣神隆股份有限公司 製備阿塔魯仁及其中間體的方法
WO2020128816A2 (en) 2018-12-20 2020-06-25 Pfizer Inc. Pharmaceutical compositions and methods comprising a combination of a benzoxazole transthyretin stabilizer and an additional therapeutic agent
WO2020210432A1 (en) 2019-04-10 2020-10-15 Ptc Therapeutics, Inc. Method for treating nonsense mutation mediated duchenne muscular dystrophy in pediatric patients
WO2022112919A1 (en) 2020-11-25 2022-06-02 Pfizer Inc. (aza)benzothiazolyl substituted pyrazole compounds
CN113045510B (zh) * 2021-03-31 2022-05-27 北京大学生命科学华东产业研究院 一种阿塔鲁伦的制备方法
CN114920667B (zh) * 2022-06-30 2024-06-21 湖南大学 一种阿塔鲁伦酯的电化学制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2801509A1 (de) * 1978-01-12 1979-07-19 Schering Ag 1,2,4-oxadiazolderivate, verfahren zur herstellung dieser verbindungen sowie diese enthaltende selektive herbizide mittel
DE3905242A1 (de) * 1989-02-21 1990-08-23 Basf Ag Verfahren zur herstellung von phenyloxdiazolylanilinen
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
DE4425794A1 (de) * 1994-07-21 1996-01-25 Basf Ag Nitrofarbstoffe
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
KR20040004705A (ko) * 2001-06-08 2004-01-13 시토비아 인크. 카스파제의 활성제 및 아폽토시스의 유도제로서의 치환된3-아릴-5-아릴-[1,2,4]-옥사디아졸과 유사체 및 이의 용도
MY151199A (en) * 2001-11-02 2014-04-30 Rigel Pharmaceuticals Inc Substituted diphenyl heterocycles useful for treating hcv infection
AU2003268064A1 (en) * 2002-08-09 2004-02-25 Astrazeneca Ab Oxadiazoles as modulators of metabotropic glutamate receptor-5
GB0303503D0 (en) 2003-02-14 2003-03-19 Novartis Ag Organic compounds
EP3345895B1 (en) * 2003-04-11 2019-12-04 PTC Therapeutics, Inc. 1,2,4-oxadiazole benzoic acid compound and its use for nonsense suppression and the treatment of disease
WO2004110351A2 (en) * 2003-05-14 2004-12-23 Anadys Pharmaceuticals, Inc. Heterocyclic compounds for treating hepatitis c virus
CA2603402C (en) * 2005-04-08 2017-10-31 Ptc Therapeutics, Inc. Compositions of an orally active 1,2,4-oxadiazole for nonsense mutation suppression therapy
ES2404348T3 (es) * 2006-09-08 2013-05-27 Ptc Therapeutics, Inc. Procedimiento para la preparación de ácidos 1, 2, 4-oxadiazol-benzoicos

Also Published As

Publication number Publication date
PE20120669A1 (es) 2012-06-01
CA2842625C (en) 2016-07-12
EP2059513B1 (en) 2013-01-23
CA2662749C (en) 2015-01-20
MY148598A (en) 2013-05-15
WO2008030570A1 (en) 2008-03-13
PT2059513E (pt) 2013-04-30
CA2842625A1 (en) 2008-03-13
AR118922A2 (es) 2021-11-10
US20080139818A1 (en) 2008-06-12
US7678922B2 (en) 2010-03-16
BRPI0716996B8 (pt) 2021-05-25
DK2059513T3 (da) 2013-05-06
AR062715A1 (es) 2008-11-26
IL197445A0 (en) 2009-12-24
TWI482761B (zh) 2015-05-01
NZ575511A (en) 2012-02-24
RU2009113019A (ru) 2010-10-20
CN101535284B (zh) 2014-12-10
US8367841B2 (en) 2013-02-05
RU2495030C2 (ru) 2013-10-10
IL197445A (en) 2014-01-30
AR107474A2 (es) 2018-05-02
BRPI0716996B1 (pt) 2021-02-09
KR101466368B1 (ko) 2014-11-27
BRPI0716996A2 (pt) 2013-10-08
JP2014193896A (ja) 2014-10-09
TW200823180A (en) 2008-06-01
CL2007002606A1 (es) 2008-04-18
AU2007292915A1 (en) 2008-03-13
KR20090054464A (ko) 2009-05-29
JP5955494B2 (ja) 2016-07-20
CN101535284A (zh) 2009-09-16
ES2404348T3 (es) 2013-05-27
US20100063297A1 (en) 2010-03-11
NZ598012A (en) 2013-08-30
JP2010502715A (ja) 2010-01-28
ZA200901782B (en) 2010-06-30
CA2662749A1 (en) 2008-03-13
PE20080771A1 (es) 2008-06-13
MX2009002439A (es) 2009-03-27
EP2059513A1 (en) 2009-05-20
HK1134094A1 (en) 2010-04-16
UA99265C2 (ru) 2012-08-10
AU2007292915B2 (en) 2012-07-26

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