PL2010649T3 - Ulepszone mutanty rozpuszczalnej dehydrogenazy glukozowej zależnej od chinonu pirolochinoliny - Google Patents

Ulepszone mutanty rozpuszczalnej dehydrogenazy glukozowej zależnej od chinonu pirolochinoliny

Info

Publication number
PL2010649T3
PL2010649T3 PL07724148T PL07724148T PL2010649T3 PL 2010649 T3 PL2010649 T3 PL 2010649T3 PL 07724148 T PL07724148 T PL 07724148T PL 07724148 T PL07724148 T PL 07724148T PL 2010649 T3 PL2010649 T3 PL 2010649T3
Authority
PL
Poland
Prior art keywords
glucose dehydrogenase
pyrroloquinoline quinone
soluble glucose
dependent soluble
improved mutants
Prior art date
Application number
PL07724148T
Other languages
English (en)
Inventor
Mara Boenitz-Dulat
Daniela Beck
Peter Kratzsch
Rainer Schmuck
Der Eltz Herbert Von
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36579921&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2010649(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL2010649T3 publication Critical patent/PL2010649T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL07724148T 2006-04-13 2007-04-11 Ulepszone mutanty rozpuszczalnej dehydrogenazy glukozowej zależnej od chinonu pirolochinoliny PL2010649T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06007779 2006-04-13
EP07724148.7A EP2010649B1 (en) 2006-04-13 2007-04-11 Improved mutants of pyrroloquinoline quinone dependent soluble glucose dehydrogenase

Publications (1)

Publication Number Publication Date
PL2010649T3 true PL2010649T3 (pl) 2017-08-31

Family

ID=36579921

Family Applications (2)

Application Number Title Priority Date Filing Date
PL17151869T PL3246402T3 (pl) 2006-04-13 2007-04-11 Ulepszone mutanty rozpuszczalnej dehydrogenazy glukozowej zależnej od pirolochinolinochinonu
PL07724148T PL2010649T3 (pl) 2006-04-13 2007-04-11 Ulepszone mutanty rozpuszczalnej dehydrogenazy glukozowej zależnej od chinonu pirolochinoliny

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL17151869T PL3246402T3 (pl) 2006-04-13 2007-04-11 Ulepszone mutanty rozpuszczalnej dehydrogenazy glukozowej zależnej od pirolochinolinochinonu

Country Status (14)

Country Link
US (1) US7732179B2 (pl)
EP (2) EP2010649B1 (pl)
JP (3) JP5683809B2 (pl)
KR (1) KR101168623B1 (pl)
CN (1) CN101421396B (pl)
AU (1) AU2007237478B2 (pl)
BR (1) BRPI0710131B1 (pl)
CA (1) CA2649135C (pl)
ES (2) ES2624805T3 (pl)
HU (2) HUE049911T2 (pl)
MX (1) MX2008013001A (pl)
PL (2) PL3246402T3 (pl)
PT (2) PT2010649T (pl)
WO (1) WO2007118647A1 (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5753720B2 (ja) * 2010-04-22 2015-07-22 アークレイ株式会社 バイオセンサ
US20130092536A1 (en) 2010-07-23 2013-04-18 Roche Diagnostics Operations, Inc. Zwitterion buffer containing compositions and uses in electroanalytical methods
US20130337485A1 (en) 2010-12-20 2013-12-19 Lek Pharmaceuticals D.D Enzymatic synthesis of active pharmaceutical ingredient and intermediates thereof
EP2465936A1 (en) 2010-12-20 2012-06-20 LEK Pharmaceuticals d.d. Enzymatic synthesis of statins and intermediates thereof
EP3901624B1 (en) 2010-12-22 2024-01-31 Roche Diabetes Care GmbH Methods to compensate for sources of error during electrochemical testing
CN102559624B (zh) * 2012-03-05 2013-10-16 浙江德清汇宁生物科技有限公司 一种吡咯喹啉醌依赖型葡萄糖脱氢酶的热稳定性突变体及其高通量筛选方法
CA2865678C (en) 2012-04-19 2018-03-13 Susanne BALDUS Method and device for determining an analyte concentration in blood
EP2811299A1 (en) 2013-06-07 2014-12-10 Roche Diagniostics GmbH Test element for detecting at least one analyte in a body fluid
JP6998863B2 (ja) 2015-09-25 2022-02-04 エフ．ホフマン－ラ ロシュ アーゲー 深共融溶媒におけるソルターゼａを利用したアミド基転移
WO2017050874A1 (en) 2015-09-25 2017-03-30 F. Hoffmann-La Roche Ag Process for producing thioesters employing a sortase a
CN105331590B (zh) * 2015-10-29 2020-02-28 英科隆生物技术（杭州）有限公司 葡萄糖特异性改善的可溶性吡咯喹啉醌依赖性葡萄糖脱氢酶突变体、聚核苷酸及其应用
CN111073866B (zh) 2015-10-29 2024-03-19 英科隆生物技术（杭州）有限公司 PQQ-sGDH突变体、聚核苷酸及其在葡萄糖检测中的应用
CN108350439A (zh) 2015-12-21 2018-07-31 豪夫迈·罗氏有限公司 来自粪产碱菌的突变体3-羟基丁酸脱氢酶及其相关方法和用途
WO2017137491A1 (en) 2016-02-09 2017-08-17 Roche Diabetes Care Gmbh Mutant 3-hydroxybutyrate dehydrogenase from rhodobacter sphaeroides as well as methods and uses involving the same
PL3523639T3 (pl) 2016-10-05 2025-03-17 F. Hoffmann-La Roche Ag Odczynniki wykrywające i układy elektrod do elementów diagnostycznych testów wieloanalitowych oraz sposoby ich zastosowania
CN115820608B (zh) * 2022-08-31 2024-06-04 中国海洋大学 λ-卡拉胶酶突变体OUC-CglA-DPQQ及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3716957A1 (de) 1987-05-20 1988-12-01 Boehringer Mannheim Gmbh Expressionsvektor zur regulierbaren expression von fremdgenen in prokaryonten
DE4311464A1 (de) 1993-04-08 1994-10-13 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen Bestimmung eines Analyten mit einer PQQ-abhängigen Dehydrogenase
DE19639169A1 (de) 1996-09-24 1998-04-02 Boehringer Mannheim Gmbh Redoxaktive Verbindungen und deren Anwendung
JPH10243786A (ja) 1997-03-03 1998-09-14 Koji Hayade 改変型グルコース脱水素酵素
US5997817A (en) 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
JPH11243949A (ja) 1998-03-03 1999-09-14 Toyobo Co Ltd Ｐｑｑを補欠分子族とするグルコースデヒドロゲナーゼおよびその製造方法
CA2368461A1 (en) * 1999-02-19 2000-08-24 Winfried Linxweiler Glucose dehydrogenase fusion proteins and their utilization in expression systems
JP2000350588A (ja) * 1999-04-08 2000-12-19 Koji Hayade グルコース脱水素酵素
TWI224136B (en) 1999-04-30 2004-11-21 Koji Sode Glucose dehydrogenase
JP3845618B2 (ja) * 2000-10-27 2006-11-15 エフ．ホフマン−ラ ロシュ アーゲー 可溶性ピロロキノリンキノン−依存性グルコースデヒドロゲナーゼのバリアント
JP2004344145A (ja) * 2002-05-27 2004-12-09 Toyobo Co Ltd 基質特異性または安定性に優れたピロロキノリンキノン（ｐｑｑ）依存性グルコースデヒドロゲナーゼ改変体
JP2004173538A (ja) * 2002-11-25 2004-06-24 Amano Enzyme Inc ピロロキノリンキノン依存性グルコース脱水素酵素
CA2570593C (en) * 2004-07-20 2012-03-20 F. Hoffmann-La Roche Ag Genetically engineered pyrroloquinoline quinone dependent glucose dehydrogenase comprising an amino acid insertion

Also Published As

Publication number Publication date
EP3246402A1 (en) 2017-11-22
PL3246402T3 (pl) 2020-10-19
BRPI0710131B1 (pt) 2020-03-10
EP3246402B1 (en) 2020-05-20
AU2007237478B2 (en) 2011-05-19
US7732179B2 (en) 2010-06-08
PT2010649T (pt) 2017-05-03
HUE049911T2 (hu) 2020-11-30
ES2807530T3 (es) 2021-02-23
PT3246402T (pt) 2020-07-14
ES2624805T3 (es) 2017-07-17
HUE032804T2 (en) 2017-11-28
CA2649135A1 (en) 2007-10-25
MX2008013001A (es) 2008-10-17
EP2010649A1 (en) 2009-01-07
AU2007237478A1 (en) 2007-10-25
JP2016119904A (ja) 2016-07-07
HK1131633A1 (zh) 2010-01-29
US20090148874A1 (en) 2009-06-11
JP5683809B2 (ja) 2015-03-11
JP6185617B2 (ja) 2017-08-23
KR101168623B1 (ko) 2012-08-03
JP2009533033A (ja) 2009-09-17
CA2649135C (en) 2013-11-19
CN101421396B (zh) 2016-01-20
CN101421396A (zh) 2009-04-29
JP2013198497A (ja) 2013-10-03
JP5937547B2 (ja) 2016-06-22
KR20080106349A (ko) 2008-12-04
EP2010649B1 (en) 2017-03-08
BRPI0710131A2 (pt) 2011-08-02
WO2007118647A1 (en) 2007-10-25

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