PL2201122T3 - Enancjoselektywna enzymatyczna redukcja ketozwiązków - Google Patents

Enancjoselektywna enzymatyczna redukcja ketozwiązków

Info

Publication number
PL2201122T3
PL2201122T3 PL08802486T PL08802486T PL2201122T3 PL 2201122 T3 PL2201122 T3 PL 2201122T3 PL 08802486 T PL08802486 T PL 08802486T PL 08802486 T PL08802486 T PL 08802486T PL 2201122 T3 PL2201122 T3 PL 2201122T3
Authority
PL
Poland
Prior art keywords
enzymatic reduction
keto compounds
enantioselective enzymatic
enantioselective
keto
Prior art date
Application number
PL08802486T
Other languages
English (en)
Inventor
Antje Gupta
Maria Dupont
Anke Tschentscher
Original Assignee
Cambrex Iep Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambrex Iep Gmbh filed Critical Cambrex Iep Gmbh
Publication of PL2201122T3 publication Critical patent/PL2201122T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL08802486T 2007-09-27 2008-09-22 Enancjoselektywna enzymatyczna redukcja ketozwiązków PL2201122T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT15302007 2007-09-27
EP08802486.4A EP2201122B1 (en) 2007-09-27 2008-09-22 Enantioselective enzymatic reduction of keto compounds
PCT/EP2008/007992 WO2009040080A1 (en) 2007-09-27 2008-09-22 Process for the enantioselective enzymatic reduction of intermediates

Publications (1)

Publication Number Publication Date
PL2201122T3 true PL2201122T3 (pl) 2018-01-31

Family

ID=40352741

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08802486T PL2201122T3 (pl) 2007-09-27 2008-09-22 Enancjoselektywna enzymatyczna redukcja ketozwiązków

Country Status (14)

Country Link
US (1) US8932835B2 (pl)
EP (1) EP2201122B1 (pl)
JP (1) JP2010539910A (pl)
KR (1) KR101474815B1 (pl)
CN (1) CN101809158B (pl)
AU (1) AU2008303842B2 (pl)
CA (1) CA2697038C (pl)
ES (1) ES2647069T3 (pl)
HU (1) HUE035577T2 (pl)
PL (1) PL2201122T3 (pl)
PT (1) PT2201122T (pl)
TW (1) TWI601825B (pl)
WO (1) WO2009040080A1 (pl)
ZA (1) ZA201001052B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3409765B1 (en) 2009-06-22 2021-08-04 Codexis, Inc. Ketoreductase-mediated stereoselective route to alpha chloroalcohols
BRPI0924997B1 (pt) 2009-06-22 2024-01-16 Sk Biopharmaceuticals Co., Ltd Método para preparar um composto de éster do ácido 1-aril-2- tetrazoil etil carbâmico
US8404461B2 (en) * 2009-10-15 2013-03-26 SK Biopharmaceutical Co. Ltd. Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester
US9080192B2 (en) 2010-02-10 2015-07-14 Codexis, Inc. Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system
EA027209B1 (ru) * 2012-06-18 2017-06-30 Лабораторио Кимико Интернационале С.П.А. Ферментативное восстановление
DE102013104418B4 (de) * 2013-04-30 2018-09-27 Cambrex Iep Gmbh Biokatalytisches Verfahren für die Herstellung von (R)-3-Chinuclidinol
WO2019012095A1 (en) 2017-07-14 2019-01-17 C-Lecta Gmbh TCO-reductase
CN111836899B (zh) * 2017-12-20 2024-06-25 欧伦股份公司 制备用于通过酶还原合成光学活性β-氨基醇的中间体的方法以及合成中间体
CN111690696B (zh) * 2020-07-07 2021-12-31 南京朗恩生物科技有限公司 一种生物催化制备达芦那韦中间体的方法
CN114540456A (zh) * 2020-11-25 2022-05-27 弈柯莱生物科技(上海)股份有限公司 拆分2-(苄氧基羰基氨基)-2-(氧杂环丁烷-3-基)乙酸甲酯的方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4014573C1 (pl) 1990-05-07 1991-10-10 Forschungszentrum Juelich Gmbh, 5170 Juelich, De
JP3672307B2 (ja) 1992-03-13 2005-07-20 フォルシュングスツェントルム・ユーリッヒ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 新規ケトエステル‐還元酵素，その製造方法及びこれを酵素酸化還元反応に使用する方法
JP3574682B2 (ja) 1993-09-24 2004-10-06 ダイセル化学工業株式会社 新規な酵素、該酵素を製造する方法、該酵素をコードするｄｎａ、該ｄｎａを含む形質転換体、該酵素による光学活性アルコール等の製造方法
JP3529904B2 (ja) * 1995-06-19 2004-05-24 鐘淵化学工業株式会社 光学活性１−ハロ−３−アミノ−４−フェニル−２−ブタノール誘導体の製造法
DE19610984A1 (de) 1996-03-21 1997-09-25 Boehringer Mannheim Gmbh Alkohol-Dehydrogenase und deren Verwendung zur enzymatischen Herstellung chiraler Hydroxyverbindungen
USH1893H (en) * 1996-07-23 2000-10-03 Bristol-Myers Squibb Company Enzymatic reduction method for the preparation of halohydrins
US6737264B1 (en) * 1999-01-21 2004-05-18 Kaneka Corporation Method for purifying and isolating (2s,3s)- or (2r,3s)-halohydrin derivatives
JP2001149088A (ja) 1999-11-24 2001-06-05 Nippon Kayaku Co Ltd 光学活性１−置換−３−アミノ−４−フェニル−２−ブタノール誘導体の製造方法
CA2360376C (en) * 1999-12-03 2005-04-26 Noriyuki Kizaki Novel carbonyl reductase, gene thereof and method of using the same
US20020042124A1 (en) 2000-08-16 2002-04-11 Patel Ramesh N. Stereoselective reduction of substituted oxo-butanes
DE10119274A1 (de) 2001-04-20 2002-10-31 Juelich Enzyme Products Gmbh Enzymatisches Verfahren zur enantioselektiven Reduktion von Ketoverbindungen
JP2003289874A (ja) * 2002-04-03 2003-10-14 Kanegafuchi Chem Ind Co Ltd 共役ポリケトン還元酵素遺伝子とその利用
DE10327454A1 (de) * 2003-06-18 2005-01-20 Juelich Enzyme Products Gmbh Oxidoreduktase aus Pichia capsulata
WO2006046455A1 (ja) * 2004-10-27 2006-05-04 Kaneka Corporation 新規カルボニル還元酵素、その遺伝子、およびその利用法
AT501496B1 (de) * 2005-02-21 2007-03-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
AT502395B1 (de) 2005-07-27 2007-03-15 Iep Gmbh Oxidoreduktasen zur stereoselektiven reduktion von ketoverbindungen
DE102005044736A1 (de) * 2005-09-19 2007-03-22 Basf Ag Neue Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von optisch aktiven Alkanolen
AT502185B1 (de) * 2005-09-23 2007-02-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
AT503017B1 (de) * 2005-12-19 2007-07-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von hydroxyketoverbindungen
AT504542B1 (de) * 2006-12-07 2008-09-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von secodionderivaten

Also Published As

Publication number Publication date
AU2008303842B2 (en) 2014-07-31
TWI601825B (zh) 2017-10-11
PT2201122T (pt) 2017-11-15
ZA201001052B (en) 2011-04-28
RU2010116394A (ru) 2011-11-10
WO2009040080A1 (en) 2009-04-02
TW200920846A (en) 2009-05-16
CA2697038A1 (en) 2009-04-02
EP2201122B1 (en) 2017-08-16
JP2010539910A (ja) 2010-12-24
KR101474815B1 (ko) 2014-12-19
HUE035577T2 (en) 2018-05-28
CN101809158A (zh) 2010-08-18
KR20100065344A (ko) 2010-06-16
US20100248317A1 (en) 2010-09-30
ES2647069T3 (es) 2017-12-19
CA2697038C (en) 2013-06-18
AU2008303842A1 (en) 2009-04-02
CN101809158B (zh) 2015-04-08
EP2201122A1 (en) 2010-06-30
US8932835B2 (en) 2015-01-13

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