PL200682B1 - Pochodne pirazyny, sposoby ich wytwarzania i zastosowanie oraz kompozycja farmaceutyczna - Google Patents

Pochodne pirazyny, sposoby ich wytwarzania i zastosowanie oraz kompozycja farmaceutyczna

Info

Publication number
PL200682B1
PL200682B1 PL348768A PL34876800A PL200682B1 PL 200682 B1 PL200682 B1 PL 200682B1 PL 348768 A PL348768 A PL 348768A PL 34876800 A PL34876800 A PL 34876800A PL 200682 B1 PL200682 B1 PL 200682B1
Authority
PL
Poland
Prior art keywords
choh
alk
cycloalk
carbon atoms
cor
Prior art date
Application number
PL348768A
Other languages
English (en)
Polish (pl)
Other versions
PL348768A1 (en
Inventor
Hervé Bouchard
Alain Commercon
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of PL348768A1 publication Critical patent/PL348768A1/xx
Publication of PL200682B1 publication Critical patent/PL200682B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL348768A 1999-01-11 2000-01-07 Pochodne pirazyny, sposoby ich wytwarzania i zastosowanie oraz kompozycja farmaceutyczna PL200682B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9900186A FR2788274B1 (fr) 1999-01-11 1999-01-11 Nouveaux derives de polyhydroxypyrazines, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR2000/000026 WO2000042027A1 (fr) 1999-01-11 2000-01-07 Nouveaux derives de polyhydroxypyrazines, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
PL348768A1 PL348768A1 (en) 2002-06-03
PL200682B1 true PL200682B1 (pl) 2009-01-30

Family

ID=9540746

Family Applications (1)

Application Number Title Priority Date Filing Date
PL348768A PL200682B1 (pl) 1999-01-11 2000-01-07 Pochodne pirazyny, sposoby ich wytwarzania i zastosowanie oraz kompozycja farmaceutyczna

Country Status (24)

Country Link
US (1) US6818637B2 (de)
EP (1) EP1140861B1 (de)
JP (1) JP4516694B2 (de)
KR (1) KR100648324B1 (de)
CN (1) CN1145615C (de)
AT (1) ATE244226T1 (de)
AU (1) AU774627B2 (de)
BR (1) BR0007449B1 (de)
CA (1) CA2359463C (de)
CZ (1) CZ301380B6 (de)
DE (1) DE60003631T2 (de)
DK (1) DK1140861T3 (de)
EA (1) EA003550B1 (de)
ES (1) ES2198273T3 (de)
FR (1) FR2788274B1 (de)
HU (1) HU228761B1 (de)
IL (2) IL143945A0 (de)
NO (1) NO320398B1 (de)
NZ (1) NZ512911A (de)
PL (1) PL200682B1 (de)
PT (1) PT1140861E (de)
SK (1) SK286389B6 (de)
WO (1) WO2000042027A1 (de)
ZA (1) ZA200105657B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100425596C (zh) * 2006-03-29 2008-10-15 中国烟草总公司郑州烟草研究院 脱氧果糖嗪的制备方法
CN101697972B (zh) * 2009-11-16 2011-08-10 朱峰 新曲霉酸在制备抗肿瘤药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2238081A1 (en) * 1995-11-22 1997-05-29 S. Jane Desolms Inhibitors of farnesyl-protein transferase
FR2744365B1 (fr) * 1996-02-06 1998-02-27 Inst Malgache Rech Appl Melanges isolables a partir de graines d'eugenia jambolana lamarck, leur preparation et l'utilisation de ces melanges et certains de leurs constituants comme medicaments
FR2766185B1 (fr) * 1997-07-18 2001-06-15 Rhone Poulenc Rorer Sa Medicaments contenant en tant que principe actif au moins un derive substitue de polyhydroxylalkylpyrazines, les nouveaux derives polyhydroxylalkylpyrazines et leur preparation

Also Published As

Publication number Publication date
US6818637B2 (en) 2004-11-16
PT1140861E (pt) 2003-11-28
IL143945A0 (en) 2002-04-21
EA003550B1 (ru) 2003-06-26
ZA200105657B (en) 2002-10-10
AU774627B2 (en) 2004-07-01
NO20013416L (no) 2001-09-06
CZ20012483A3 (cs) 2001-10-17
CZ301380B6 (cs) 2010-02-03
FR2788274A1 (fr) 2000-07-13
US20020077324A1 (en) 2002-06-20
NZ512911A (en) 2003-10-31
WO2000042027A1 (fr) 2000-07-20
CA2359463A1 (fr) 2000-07-20
SK9762001A3 (en) 2001-12-03
DE60003631D1 (de) 2003-08-07
ES2198273T3 (es) 2004-02-01
NO320398B1 (no) 2005-11-28
EP1140861B1 (de) 2003-07-02
IL143945A (en) 2006-04-10
SK286389B6 (sk) 2008-09-05
EA200100767A1 (ru) 2001-12-24
CN1352638A (zh) 2002-06-05
JP2002534513A (ja) 2002-10-15
CN1145615C (zh) 2004-04-14
NO20013416D0 (no) 2001-07-10
PL348768A1 (en) 2002-06-03
JP4516694B2 (ja) 2010-08-04
HUP0105104A3 (en) 2002-09-30
HU228761B1 (en) 2013-05-28
CA2359463C (fr) 2009-09-15
DE60003631T2 (de) 2004-06-03
DK1140861T3 (da) 2003-10-20
BR0007449B1 (pt) 2011-08-09
HUP0105104A2 (hu) 2002-07-29
ATE244226T1 (de) 2003-07-15
AU3051500A (en) 2000-08-01
BR0007449A (pt) 2001-10-16
KR20010101456A (ko) 2001-11-14
FR2788274B1 (fr) 2001-02-09
EP1140861A1 (de) 2001-10-10
KR100648324B1 (ko) 2006-11-23

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