PL1861100T3 - 3,11b-cis-Dihydrotetrabenazyna do leczenia chorób proliferacyjnych lub stanów zapalnych - Google Patents
3,11b-cis-Dihydrotetrabenazyna do leczenia chorób proliferacyjnych lub stanów zapalnychInfo
- Publication number
- PL1861100T3 PL1861100T3 PL06765213T PL06765213T PL1861100T3 PL 1861100 T3 PL1861100 T3 PL 1861100T3 PL 06765213 T PL06765213 T PL 06765213T PL 06765213 T PL06765213 T PL 06765213T PL 1861100 T3 PL1861100 T3 PL 1861100T3
- Authority
- PL
- Poland
- Prior art keywords
- dihydrotetrabenazine
- cis
- treatment
- inflammation
- proliferative disease
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 230000002062 proliferating effect Effects 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 title 1
- 230000004054 inflammatory process Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0516168.2A GB0516168D0 (en) | 2005-08-05 | 2005-08-05 | Pharmaceutical compounds |
| PCT/GB2006/002909 WO2007017643A1 (en) | 2005-08-05 | 2006-08-04 | 3 , llB-CIS-DIHYDROTETRABENAZINE FOR THE TREATMENT OF A PROLIFERATIVE DISEASE OR AN INFLAMMATION |
| EP06765213A EP1861100B1 (en) | 2005-08-05 | 2006-08-04 | 3,11b-cis-dihydrotetrabenazine for the treatment of a proliferative disease or an inflammation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1861100T3 true PL1861100T3 (pl) | 2009-06-30 |
Family
ID=34984180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06765213T PL1861100T3 (pl) | 2005-08-05 | 2006-08-04 | 3,11b-cis-Dihydrotetrabenazyna do leczenia chorób proliferacyjnych lub stanów zapalnych |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20090275605A1 (enExample) |
| EP (2) | EP1964565A1 (enExample) |
| JP (1) | JP2009503045A (enExample) |
| KR (1) | KR20080033501A (enExample) |
| CN (1) | CN101321528B (enExample) |
| AT (1) | ATE412414T1 (enExample) |
| AU (1) | AU2006277836B8 (enExample) |
| CA (1) | CA2620952A1 (enExample) |
| CY (1) | CY1108729T1 (enExample) |
| DE (1) | DE602006003415D1 (enExample) |
| DK (1) | DK1861100T3 (enExample) |
| ES (1) | ES2317564T3 (enExample) |
| GB (1) | GB0516168D0 (enExample) |
| HR (1) | HRP20090017T3 (enExample) |
| MX (1) | MX2008001546A (enExample) |
| NZ (1) | NZ566010A (enExample) |
| PL (1) | PL1861100T3 (enExample) |
| PT (1) | PT1861100E (enExample) |
| RS (1) | RS50720B (enExample) |
| RU (1) | RU2409364C2 (enExample) |
| SI (1) | SI1861100T1 (enExample) |
| WO (1) | WO2007017643A1 (enExample) |
| ZA (2) | ZA200801170B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2410947B (en) * | 2004-02-11 | 2008-09-17 | Cambridge Lab Ltd | Pharmaceutical compounds |
| GB0514501D0 (en) * | 2005-07-14 | 2005-08-24 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
| DK2081929T3 (da) | 2006-11-08 | 2013-04-15 | Neurocrine Biosciences Inc | Substituerede 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11B-hexahydro-2H-pyrido[2,1-A]isoquinolin-2-ol-forbindelser og fremgangsmåder angående disse |
| GB0721669D0 (en) * | 2007-11-02 | 2007-12-12 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
| GB0810857D0 (en) * | 2008-06-13 | 2008-07-23 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
| GB2462611A (en) * | 2008-08-12 | 2010-02-17 | Cambridge Lab | Pharmaceutical composition comprising tetrabenazine |
| US20110053866A1 (en) * | 2008-08-12 | 2011-03-03 | Biovail Laboratories International (Barbados) S.R.L. | Pharmaceutical compositions |
| GB2463452A (en) * | 2008-09-08 | 2010-03-17 | Cambridge Lab | Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof |
| GB2463451A (en) | 2008-09-08 | 2010-03-17 | Cambridge Lab | 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia |
| GB2463283A (en) * | 2008-09-08 | 2010-03-10 | Cambridge Lab | 3,11b-cis-dihydrotetrabenazine for use in treating asthma |
| US20120003330A1 (en) | 2010-06-01 | 2012-01-05 | Auspex Pharmaceuticals, Inc. | Benzoquinolone inhibitors of vmat2 |
| CN102285984B (zh) * | 2010-11-25 | 2012-10-10 | 江苏威凯尔医药科技有限公司 | (2R,3R,11bR)-二氢丁苯那嗪及相关化合物的制备方法 |
| KR20160111999A (ko) | 2014-01-27 | 2016-09-27 | 오스펙스 파마슈티칼스, 인코포레이티드 | 소포성 모노아민 수송체 2의 벤조퀴놀린 억제제 |
| MA41177A (fr) * | 2014-12-15 | 2017-10-24 | Esteve Labor Dr | Utilisation de ligands des récepteurs sigma dans l'arthrose |
| US10550120B2 (en) | 2016-03-25 | 2020-02-04 | Tohoku University | Indole alkaloid compound having immune checkpoint inhibitory action |
| CN109283279B (zh) * | 2017-07-21 | 2019-11-01 | 南京正大天晴制药有限公司 | 通过高效液相色谱法分离测定雷替曲塞及其对映异构体的方法 |
| CN109283263B (zh) * | 2017-07-21 | 2019-06-25 | 南京正大天晴制药有限公司 | 用于雷替曲塞合成质量控制的检测分析方法 |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3009918A (en) * | 1961-11-21 | Chz ch | ||
| US2830993A (en) * | 1958-04-15 | Quinolizine derivatives | ||
| US3132147A (en) * | 1964-05-05 | |||
| US3209005A (en) * | 1965-09-28 | Hexahydro-llbh-benzo[a] quinolizines and processes therefor | ||
| US3079395A (en) * | 1963-02-26 | Novel z-oxq-benzoquinoliaine | ||
| US3095419A (en) * | 1963-06-25 | Process for preparing z-oxo-j- | ||
| US3123609A (en) * | 1964-03-03 | Benzo | ||
| US3159638A (en) * | 1964-12-01 | Xcha-chj | ||
| US3314966A (en) * | 1967-04-18 | Substituted benzo[a]quinolizines | ||
| US2954382A (en) * | 1960-09-27 | Xpreparation of hexahydrobenzoquinol- | ||
| US2843591A (en) | 1958-07-15 | Method for preparing same | ||
| US3053845A (en) * | 1962-09-11 | Benzofykedocolines | ||
| US3045021A (en) * | 1959-09-24 | 1962-07-17 | Hoffmann La Roche | Preparation of substituted 2-oxobenzoquinolizines |
| GB999092A (en) * | 1959-11-24 | 1965-07-21 | Wellcome Found | Method for making benzo(a)-quinolizine derivatives |
| US3375254A (en) * | 1961-09-29 | 1968-03-26 | Burroughs Wellcome Co | Manufacture of 1, 2, 3, 4, 6, 7-hexahydro-2-oxo-11bh-benzo(a)quinolizines |
| US3105079A (en) * | 1961-12-29 | 1963-09-24 | Pfizer & Co C | 10-aminobenzopyridocolines |
| US3390152A (en) * | 1965-10-21 | 1968-06-25 | Abbott Lab | 9, 10-alkoxy-3-alkyl-2, 2-(dithiosubstituted)-benzoquinolizines |
| US3634431A (en) * | 1969-12-22 | 1972-01-11 | Miles Lab | Acylated and alkylated derivatives of 2-aminohexahydrobenzo(a)quinolizines |
| US3635986A (en) * | 1969-12-22 | 1972-01-18 | Miles Lab | 2-substituted amino-hexahydrobenzo(a)quinolizines |
| YU264675A (en) * | 1974-10-23 | 1982-05-31 | Chinoin Gyogyszer Es Vegyeszet | Process for obtaining benzo (a)-quinolizidine derivatives |
| GB1513824A (en) * | 1975-05-22 | 1978-06-14 | Wyeth John & Brother Ltd | 1,3,4,6,7,11b-hexahydro-2h-benzo(a)quinolizine derivative |
| US4133812A (en) * | 1975-11-21 | 1979-01-09 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. | Process for producing benzo (a) quinolizine derivatives |
| US4304913A (en) * | 1978-11-20 | 1981-12-08 | Miles Laboratories, Inc. | Trans-2-substituted-amido-hexahydrobenzo [A]quinolizines |
| US4353656A (en) * | 1980-10-14 | 1982-10-12 | Xerox Corporation | Moving coil, multiple energy print hammer system including a closed loop servo |
| US4778054A (en) * | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| AU591152B2 (en) * | 1985-07-30 | 1989-11-30 | Glaxo Group Limited | Devices for administering medicaments to patients |
| GB9004781D0 (en) * | 1990-03-02 | 1990-04-25 | Glaxo Group Ltd | Device |
| US6087376A (en) * | 1997-02-05 | 2000-07-11 | University Of Kentucky Research Foundation | Use of lobeline compounds in the treatment of central nervous system diseases and pathologies |
| FR2794742B1 (fr) * | 1999-06-11 | 2005-06-03 | Sanofi Synthelabo | Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant |
| US6632666B2 (en) * | 2000-01-14 | 2003-10-14 | Biolife Solutions, Inc. | Normothermic, hypothermic and cryopreservation maintenance and storage of cells, tissues and organs in gel-based media |
| BR0110302A (pt) * | 2000-04-18 | 2003-01-14 | Agouron Pharma | Compostos de pirazol para inibição de proteìnas cinase, sal e pró-droga farmaceuticamente aceitável, metabólito farmaceuticamente ativo ou sal farmaceuticamente aceitável de metabólito, composição farmacêutica, método de tratamento de condição doentia em mamìferos mediada pela atividade de proteìna cinase, método de modulação ou inibição da atividade de um receptor de proteìna cinase |
| PL1638529T3 (pl) * | 2003-06-16 | 2017-03-31 | Andrx Pharmaceuticals, Llc. | Kompozycja doustna o przedłużonym uwalnianiu |
| GB2410947B (en) * | 2004-02-11 | 2008-09-17 | Cambridge Lab Ltd | Pharmaceutical compounds |
| KR100682506B1 (ko) * | 2005-01-18 | 2007-02-15 | (주)젠크로스 | 프라지콴텔, 또는 이의 염을 포함하는 약학 조성물 |
| GB0514501D0 (en) * | 2005-07-14 | 2005-08-24 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
| GB0810857D0 (en) * | 2008-06-13 | 2008-07-23 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
| GB2462611A (en) * | 2008-08-12 | 2010-02-17 | Cambridge Lab | Pharmaceutical composition comprising tetrabenazine |
| US20110053866A1 (en) * | 2008-08-12 | 2011-03-03 | Biovail Laboratories International (Barbados) S.R.L. | Pharmaceutical compositions |
| GB2463451A (en) * | 2008-09-08 | 2010-03-17 | Cambridge Lab | 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia |
| GB2463452A (en) * | 2008-09-08 | 2010-03-17 | Cambridge Lab | Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof |
| GB2463283A (en) * | 2008-09-08 | 2010-03-10 | Cambridge Lab | 3,11b-cis-dihydrotetrabenazine for use in treating asthma |
-
2005
- 2005-08-05 GB GBGB0516168.2A patent/GB0516168D0/en not_active Ceased
-
2006
- 2006-08-04 JP JP2008524588A patent/JP2009503045A/ja active Pending
- 2006-08-04 EP EP08104275A patent/EP1964565A1/en not_active Withdrawn
- 2006-08-04 HR HR20090017T patent/HRP20090017T3/xx unknown
- 2006-08-04 ZA ZA200801170A patent/ZA200801170B/xx unknown
- 2006-08-04 PT PT06765213T patent/PT1861100E/pt unknown
- 2006-08-04 RS RSP-2009/0015A patent/RS50720B/sr unknown
- 2006-08-04 PL PL06765213T patent/PL1861100T3/pl unknown
- 2006-08-04 US US11/997,675 patent/US20090275605A1/en not_active Abandoned
- 2006-08-04 EP EP06765213A patent/EP1861100B1/en not_active Expired - Lifetime
- 2006-08-04 ZA ZA200801171A patent/ZA200801171B/xx unknown
- 2006-08-04 CN CN2006800366007A patent/CN101321528B/zh not_active Expired - Fee Related
- 2006-08-04 RU RU2008108516/15A patent/RU2409364C2/ru not_active IP Right Cessation
- 2006-08-04 ES ES06765213T patent/ES2317564T3/es not_active Expired - Lifetime
- 2006-08-04 MX MX2008001546A patent/MX2008001546A/es active IP Right Grant
- 2006-08-04 DE DE602006003415T patent/DE602006003415D1/de not_active Expired - Lifetime
- 2006-08-04 CA CA002620952A patent/CA2620952A1/en not_active Abandoned
- 2006-08-04 DK DK06765213T patent/DK1861100T3/da active
- 2006-08-04 SI SI200630187T patent/SI1861100T1/sl unknown
- 2006-08-04 AU AU2006277836A patent/AU2006277836B8/en not_active Expired - Fee Related
- 2006-08-04 KR KR1020087005309A patent/KR20080033501A/ko not_active Withdrawn
- 2006-08-04 WO PCT/GB2006/002909 patent/WO2007017643A1/en not_active Ceased
- 2006-08-04 AT AT06765213T patent/ATE412414T1/de active
- 2006-08-04 NZ NZ566010A patent/NZ566010A/en not_active IP Right Cessation
-
2009
- 2009-01-27 CY CY20091100100T patent/CY1108729T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1108729T1 (el) | 2014-04-09 |
| DE602006003415D1 (de) | 2008-12-11 |
| DK1861100T3 (da) | 2008-12-15 |
| AU2006277836A1 (en) | 2007-02-15 |
| ZA200801171B (en) | 2009-08-26 |
| HK1111084A1 (en) | 2008-08-01 |
| ES2317564T3 (es) | 2009-04-16 |
| CN101321528B (zh) | 2011-05-25 |
| NZ566010A (en) | 2010-05-28 |
| GB0516168D0 (en) | 2005-09-14 |
| SI1861100T1 (sl) | 2009-04-30 |
| HRP20090017T3 (hr) | 2009-03-31 |
| EP1861100B1 (en) | 2008-10-29 |
| RS50720B (sr) | 2010-08-31 |
| ZA200801170B (en) | 2009-12-30 |
| RU2008108516A (ru) | 2009-09-10 |
| MX2008001546A (es) | 2008-04-04 |
| AU2006277836B2 (en) | 2011-11-10 |
| ATE412414T1 (de) | 2008-11-15 |
| WO2007017643A1 (en) | 2007-02-15 |
| CA2620952A1 (en) | 2007-02-15 |
| RU2409364C2 (ru) | 2011-01-20 |
| CN101321528A (zh) | 2008-12-10 |
| PT1861100E (pt) | 2008-12-26 |
| EP1964565A1 (en) | 2008-09-03 |
| KR20080033501A (ko) | 2008-04-16 |
| AU2006277836B8 (en) | 2011-12-08 |
| EP1861100A1 (en) | 2007-12-05 |
| JP2009503045A (ja) | 2009-01-29 |
| US20090275605A1 (en) | 2009-11-05 |
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