ZA200801171B - 3, IIB-CIS-dihydrotetrabenazine for the treatment of a proliferative disease or an inflammation - Google Patents

3, IIB-CIS-dihydrotetrabenazine for the treatment of a proliferative disease or an inflammation

Info

Publication number
ZA200801171B
ZA200801171B ZA200801171A ZA200801171A ZA200801171B ZA 200801171 B ZA200801171 B ZA 200801171B ZA 200801171 A ZA200801171 A ZA 200801171A ZA 200801171 A ZA200801171 A ZA 200801171A ZA 200801171 B ZA200801171 B ZA 200801171B
Authority
ZA
South Africa
Prior art keywords
dihydrotetrabenazine
cis
treatment
iib
inflammation
Prior art date
Application number
ZA200801171A
Other languages
English (en)
Inventor
Duffield Andrew John
Yarrow Jean Elisabeth
Original Assignee
Ie Cambridge Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ie Cambridge Lab Ltd filed Critical Ie Cambridge Lab Ltd
Publication of ZA200801171B publication Critical patent/ZA200801171B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA200801171A 2005-08-05 2006-08-04 3, IIB-CIS-dihydrotetrabenazine for the treatment of a proliferative disease or an inflammation ZA200801171B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0516168.2A GB0516168D0 (en) 2005-08-05 2005-08-05 Pharmaceutical compounds

Publications (1)

Publication Number Publication Date
ZA200801171B true ZA200801171B (en) 2009-08-26

Family

ID=34984180

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200801170A ZA200801170B (en) 2005-08-05 2006-08-04 3,11B-cis-dihydrotetrabenazine for the treatment of a proliferative disease or an inflammation
ZA200801171A ZA200801171B (en) 2005-08-05 2006-08-04 3, IIB-CIS-dihydrotetrabenazine for the treatment of a proliferative disease or an inflammation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA200801170A ZA200801170B (en) 2005-08-05 2006-08-04 3,11B-cis-dihydrotetrabenazine for the treatment of a proliferative disease or an inflammation

Country Status (24)

Country Link
US (1) US20090275605A1 (xx)
EP (2) EP1861100B1 (xx)
JP (1) JP2009503045A (xx)
KR (1) KR20080033501A (xx)
CN (1) CN101321528B (xx)
AT (1) ATE412414T1 (xx)
AU (1) AU2006277836B8 (xx)
CA (1) CA2620952A1 (xx)
CY (1) CY1108729T1 (xx)
DE (1) DE602006003415D1 (xx)
DK (1) DK1861100T3 (xx)
ES (1) ES2317564T3 (xx)
GB (1) GB0516168D0 (xx)
HK (1) HK1111084A1 (xx)
HR (1) HRP20090017T3 (xx)
MX (1) MX2008001546A (xx)
NZ (1) NZ566010A (xx)
PL (1) PL1861100T3 (xx)
PT (1) PT1861100E (xx)
RS (1) RS50720B (xx)
RU (1) RU2409364C2 (xx)
SI (1) SI1861100T1 (xx)
WO (1) WO2007017643A1 (xx)
ZA (2) ZA200801170B (xx)

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* Cited by examiner, † Cited by third party
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GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds
GB0514501D0 (en) * 2005-07-14 2005-08-24 Cambridge Lab Ireland Ltd Pharmaceutical compounds
CN101553487B (zh) 2006-11-08 2012-06-13 纽罗克里生物科学有限公司 取代的3-异丁基-9,10-二甲氧基-1,3,4,6,7,11b-六氢-2H-吡啶并[2,1-a]异喹啉-2-醇化合物和与其相关的方法
GB0721669D0 (en) * 2007-11-02 2007-12-12 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB0810857D0 (en) * 2008-06-13 2008-07-23 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
US20110053866A1 (en) * 2008-08-12 2011-03-03 Biovail Laboratories International (Barbados) S.R.L. Pharmaceutical compositions
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof
GB2463451A (en) * 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
JP2013527237A (ja) 2010-06-01 2013-06-27 オースペックス・ファーマシューティカルズ・インコーポレイテッド ベンゾキノロン系ｖｍａｔ２阻害剤
CN102285984B (zh) * 2010-11-25 2012-10-10 江苏威凯尔医药科技有限公司 (2R,3R,11bR)-二氢丁苯那嗪及相关化合物的制备方法
KR20160111999A (ko) 2014-01-27 2016-09-27 오스펙스 파마슈티칼스, 인코포레이티드 소포성 모노아민 수송체 2의 벤조퀴놀린 억제제
MA41177A (fr) * 2014-12-15 2017-10-24 Esteve Labor Dr Utilisation de ligands des récepteurs sigma dans l'arthrose
JP6845531B2 (ja) 2016-03-25 2021-03-17 国立大学法人東北大学 免疫チェックポイント阻害作用を有するインドールアルカロイド型化合物
CN109283263B (zh) * 2017-07-21 2019-06-25 南京正大天晴制药有限公司 用于雷替曲塞合成质量控制的检测分析方法
CN109283279B (zh) * 2017-07-21 2019-11-01 南京正大天晴制药有限公司 通过高效液相色谱法分离测定雷替曲塞及其对映异构体的方法

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KR100682506B1 (ko) * 2005-01-18 2007-02-15 (주)젠크로스 프라지콴텔, 또는 이의 염을 포함하는 약학 조성물
GB0514501D0 (en) * 2005-07-14 2005-08-24 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB0810857D0 (en) * 2008-06-13 2008-07-23 Cambridge Lab Ireland Ltd Pharmaceutical compounds
US20110053866A1 (en) * 2008-08-12 2011-03-03 Biovail Laboratories International (Barbados) S.R.L. Pharmaceutical compositions
GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
GB2463451A (en) * 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
CA2620952A1 (en) 2007-02-15
ZA200801170B (en) 2009-12-30
CY1108729T1 (el) 2014-04-09
US20090275605A1 (en) 2009-11-05
CN101321528A (zh) 2008-12-10
EP1861100B1 (en) 2008-10-29
AU2006277836B2 (en) 2011-11-10
HRP20090017T3 (en) 2009-03-31
AU2006277836A1 (en) 2007-02-15
ES2317564T3 (es) 2009-04-16
HK1111084A1 (en) 2008-08-01
RU2008108516A (ru) 2009-09-10
AU2006277836B8 (en) 2011-12-08
RU2409364C2 (ru) 2011-01-20
DK1861100T3 (da) 2008-12-15
PL1861100T3 (pl) 2009-06-30
CN101321528B (zh) 2011-05-25
EP1964565A1 (en) 2008-09-03
JP2009503045A (ja) 2009-01-29
SI1861100T1 (sl) 2009-04-30
PT1861100E (pt) 2008-12-26
WO2007017643A1 (en) 2007-02-15
NZ566010A (en) 2010-05-28
RS50720B (sr) 2010-08-31
KR20080033501A (ko) 2008-04-16
EP1861100A1 (en) 2007-12-05
MX2008001546A (es) 2008-04-04
ATE412414T1 (de) 2008-11-15
DE602006003415D1 (de) 2008-12-11
GB0516168D0 (en) 2005-09-14

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