MA41177A - Utilisation de ligands des récepteurs sigma dans l'arthrose - Google Patents

Utilisation de ligands des récepteurs sigma dans l'arthrose

Info

Publication number
MA41177A
MA41177A MA041177A MA41177A MA41177A MA 41177 A MA41177 A MA 41177A MA 041177 A MA041177 A MA 041177A MA 41177 A MA41177 A MA 41177A MA 41177 A MA41177 A MA 41177A
Authority
MA
Morocco
Prior art keywords
arthrosis
receptor ligands
sigma receptor
sigma
ligands
Prior art date
Application number
MA041177A
Other languages
English (en)
Inventor
Manuel Merlos-Roca
Jose-Miguel Vela-Hernandez
Daniel Zamanillo-Castanedo
Original Assignee
Esteve Labor Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Labor Dr filed Critical Esteve Labor Dr
Publication of MA41177A publication Critical patent/MA41177A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
MA041177A 2014-12-15 2015-12-14 Utilisation de ligands des récepteurs sigma dans l'arthrose MA41177A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14382519 2014-12-15
EP15000261 2015-01-28

Publications (1)

Publication Number Publication Date
MA41177A true MA41177A (fr) 2017-10-24

Family

ID=54936995

Family Applications (1)

Application Number Title Priority Date Filing Date
MA041177A MA41177A (fr) 2014-12-15 2015-12-14 Utilisation de ligands des récepteurs sigma dans l'arthrose

Country Status (18)

Country Link
US (1) US20170273948A1 (fr)
EP (1) EP3233078A1 (fr)
JP (1) JP2017537104A (fr)
KR (1) KR20170096130A (fr)
CN (1) CN106999473A (fr)
AU (1) AU2015365954A1 (fr)
BR (1) BR112017010845A2 (fr)
CA (1) CA2968153A1 (fr)
IL (1) IL252339A0 (fr)
MA (1) MA41177A (fr)
MX (1) MX2017007792A (fr)
PH (1) PH12017500910A1 (fr)
RU (1) RU2017125134A (fr)
SG (1) SG11201704530UA (fr)
TN (1) TN2017000201A1 (fr)
TW (1) TW201630607A (fr)
WO (1) WO2016096125A1 (fr)
ZA (1) ZA201703503B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018002435A (es) * 2015-09-02 2018-06-15 Esteve Labor Dr Sales de 1- (4- (2- ((1- (3,4-difluorofenil) -1h-pirazol-3-il) metoxi) etil) piperazin-1-il) etanona.
ES2701975R1 (es) * 2016-07-12 2019-03-01 Esteve Pharmaceuticals Sa Uso de ligandos del receptor sigma en el dolor post-herpetico
WO2020113094A1 (fr) 2018-11-30 2020-06-04 Nuvation Bio Inc. Composés pyrrole et pyrazole et leurs procédés d'utilisation
EP4059498A1 (fr) * 2021-03-16 2022-09-21 Centre Hospitalier Universitaire Vaudois (CHUV) Procédés et compositions pour le traitement de pathologies associées à une hyperminéralisation

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1634872A1 (fr) * 2004-08-27 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Dérivés de pyrazole en tant qu'inhibiteurs des récepteurs sigma
KR101352012B1 (ko) * 2004-08-27 2014-01-15 라보라토리오스 델 드라. 에스테브.에스.에이. 시그마 수용체 저해제
EP1634873A1 (fr) * 2004-08-27 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Inhibiteurs des récepteurs sigma
JP2008179541A (ja) * 2005-05-02 2008-08-07 Mochida Pharmaceut Co Ltd 神経因性疼痛治療薬
GB0516168D0 (en) * 2005-08-05 2005-09-14 Cambridge Lab Ireland Ltd Pharmaceutical compounds
US8202872B2 (en) * 2006-03-01 2012-06-19 Laboratorios Del Dr. Esteve, S.A. Pyrazole derivatives as sigma receptor inhibitors
EP1847542A1 (fr) * 2006-04-21 2007-10-24 Laboratorios del Dr. Esteve S.A. Dérivés de spiro[benzopyran] ou de spiro[benzofuran] comme antagonistes du récepteur sigma
EP1921073A1 (fr) * 2006-11-10 2008-05-14 Laboratorios del Dr. Esteve S.A. 1,2,4-Triazoles en tant qu'inhibiteurs du récepteur sigma
EP1921071A1 (fr) * 2006-11-10 2008-05-14 Laboratorios del Dr. Esteve S.A. 1,2,3-Triazoles en tant qu'inhibiteurs du récepteur sigma
EP1982987A1 (fr) * 2007-04-16 2008-10-22 Laboratorios del Dr. Esteve S.A. Dérivés de spiro-pyrano-pyrazole
EP2113501A1 (fr) * 2008-04-25 2009-11-04 Laboratorios Del. Dr. Esteve, S.A. Pyrazoles de 5-Methyl-1-(naphthalen-2-YL)-1H- utiles en tant qu'inhibiteurs de récepteur sigma
EP2335688A1 (fr) * 2009-11-25 2011-06-22 Laboratorios Del. Dr. Esteve, S.A. Compositions pharmaceutiques comprenant des ligands du récepteur sigma
EP2353598A1 (fr) * 2010-02-04 2011-08-10 Laboratorios Del. Dr. Esteve, S.A. Ligands sigma pour utilisation dans la prévention et/ou le traitement de la douleur post-opératoire
EP2395003A1 (fr) * 2010-05-27 2011-12-14 Laboratorios Del. Dr. Esteve, S.A. Composés pyrazoliques en tant qu'inhibiteurs du récepteur sigma
EP2415471A1 (fr) * 2010-08-03 2012-02-08 Laboratorios Del. Dr. Esteve, S.A. Utilisation de ligands sigma dans l'hyperalgie induite par opioïdes

Also Published As

Publication number Publication date
ZA201703503B (en) 2019-11-27
SG11201704530UA (en) 2017-07-28
MX2017007792A (es) 2017-09-18
IL252339A0 (en) 2017-07-31
JP2017537104A (ja) 2017-12-14
RU2017125134A (ru) 2019-01-17
BR112017010845A2 (pt) 2017-12-26
RU2017125134A3 (fr) 2019-05-30
AU2015365954A1 (en) 2017-06-08
PH12017500910A1 (en) 2017-12-18
EP3233078A1 (fr) 2017-10-25
WO2016096125A1 (fr) 2016-06-23
TW201630607A (zh) 2016-09-01
TN2017000201A1 (en) 2018-10-19
CA2968153A1 (fr) 2016-06-23
KR20170096130A (ko) 2017-08-23
US20170273948A1 (en) 2017-09-28
CN106999473A (zh) 2017-08-01

Similar Documents

Publication Publication Date Title
IL252620A0 (en) Identification of vsig8 as a potential vista receptor and its use to prepare vista/vsig8 modulators
IL246661B (en) Human antibodies to pd–l1
IL248579B (en) Response of microbiome to substances
CL2014002680S1 (es) Gancho
CL2014002681S1 (es) Gancho
FR3027415B1 (fr) Modulateur de phase electro­optique
MA41177A (fr) Utilisation de ligands des récepteurs sigma dans l'arthrose
BR112016022703A2 (pt) fecho de contato destacável
FR3020033B1 (fr) Ensemble pour cycle
ES1109830Y (es) " senalador de prendas"
FR3017513B1 (fr) Bavoir jetable
TH1501006596A (th) สารประกอบไบเฮทเทอโรแอริล และการใช้งานของพวกมัน
TH1601000113A (th) สารประกอบมีฤทธิ์ทางการรักษาโรคและวิธีการใช้สารเหล่านั้น
UA31276S (uk) Бахіла одноразова
UA28865S (uk) Халат одноразовий
TH1601003401A (th) แอนทิบอดีแอนทิ-dpep3 ที่ใหม่และวิธีการของการใช้งาน
GB2524711B (en) Builder's hawk
FI10638U1 (fi) Hierontakoukku
TH1501004190B (th) เครื่องนุ่งห่มแบบบัสเทียร์ที่มีความสามารถในการรองรับ
TH1501007948A (th) ชั้น TiB2 และการใช้ของชั้น TiB2 ดังกล่าว
UA30121S (uk) Серга з'єднувальна
UA30120S (uk) Серга з'єднувальна
TH1501003886A (th) น้ำยาทำความสะอาด
UA29644S (uk) Кришка-сковорода
FR3019710B1 (fr) Jardiniere et kit pour jardiniere