MA41177A - Utilisation de ligands des récepteurs sigma dans l'arthrose - Google Patents
Utilisation de ligands des récepteurs sigma dans l'arthroseInfo
- Publication number
- MA41177A MA41177A MA041177A MA41177A MA41177A MA 41177 A MA41177 A MA 41177A MA 041177 A MA041177 A MA 041177A MA 41177 A MA41177 A MA 41177A MA 41177 A MA41177 A MA 41177A
- Authority
- MA
- Morocco
- Prior art keywords
- arthrosis
- receptor ligands
- sigma receptor
- sigma
- ligands
- Prior art date
Links
- 201000008482 osteoarthritis Diseases 0.000 title 1
- 239000003982 sigma receptor ligand Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14382519 | 2014-12-15 | ||
EP15000261 | 2015-01-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA41177A true MA41177A (fr) | 2017-10-24 |
Family
ID=54936995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA041177A MA41177A (fr) | 2014-12-15 | 2015-12-14 | Utilisation de ligands des récepteurs sigma dans l'arthrose |
Country Status (18)
Country | Link |
---|---|
US (1) | US20170273948A1 (fr) |
EP (1) | EP3233078A1 (fr) |
JP (1) | JP2017537104A (fr) |
KR (1) | KR20170096130A (fr) |
CN (1) | CN106999473A (fr) |
AU (1) | AU2015365954A1 (fr) |
BR (1) | BR112017010845A2 (fr) |
CA (1) | CA2968153A1 (fr) |
IL (1) | IL252339A0 (fr) |
MA (1) | MA41177A (fr) |
MX (1) | MX2017007792A (fr) |
PH (1) | PH12017500910A1 (fr) |
RU (1) | RU2017125134A (fr) |
SG (1) | SG11201704530UA (fr) |
TN (1) | TN2017000201A1 (fr) |
TW (1) | TW201630607A (fr) |
WO (1) | WO2016096125A1 (fr) |
ZA (1) | ZA201703503B (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2018002435A (es) * | 2015-09-02 | 2018-06-15 | Esteve Labor Dr | Sales de 1- (4- (2- ((1- (3,4-difluorofenil) -1h-pirazol-3-il) metoxi) etil) piperazin-1-il) etanona. |
ES2701975R1 (es) * | 2016-07-12 | 2019-03-01 | Esteve Pharmaceuticals Sa | Uso de ligandos del receptor sigma en el dolor post-herpetico |
WO2020113094A1 (fr) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Composés pyrrole et pyrazole et leurs procédés d'utilisation |
EP4059498A1 (fr) * | 2021-03-16 | 2022-09-21 | Centre Hospitalier Universitaire Vaudois (CHUV) | Procédés et compositions pour le traitement de pathologies associées à une hyperminéralisation |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1634872A1 (fr) * | 2004-08-27 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Dérivés de pyrazole en tant qu'inhibiteurs des récepteurs sigma |
KR101352012B1 (ko) * | 2004-08-27 | 2014-01-15 | 라보라토리오스 델 드라. 에스테브.에스.에이. | 시그마 수용체 저해제 |
EP1634873A1 (fr) * | 2004-08-27 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Inhibiteurs des récepteurs sigma |
JP2008179541A (ja) * | 2005-05-02 | 2008-08-07 | Mochida Pharmaceut Co Ltd | 神経因性疼痛治療薬 |
GB0516168D0 (en) * | 2005-08-05 | 2005-09-14 | Cambridge Lab Ireland Ltd | Pharmaceutical compounds |
US8202872B2 (en) * | 2006-03-01 | 2012-06-19 | Laboratorios Del Dr. Esteve, S.A. | Pyrazole derivatives as sigma receptor inhibitors |
EP1847542A1 (fr) * | 2006-04-21 | 2007-10-24 | Laboratorios del Dr. Esteve S.A. | Dérivés de spiro[benzopyran] ou de spiro[benzofuran] comme antagonistes du récepteur sigma |
EP1921073A1 (fr) * | 2006-11-10 | 2008-05-14 | Laboratorios del Dr. Esteve S.A. | 1,2,4-Triazoles en tant qu'inhibiteurs du récepteur sigma |
EP1921071A1 (fr) * | 2006-11-10 | 2008-05-14 | Laboratorios del Dr. Esteve S.A. | 1,2,3-Triazoles en tant qu'inhibiteurs du récepteur sigma |
EP1982987A1 (fr) * | 2007-04-16 | 2008-10-22 | Laboratorios del Dr. Esteve S.A. | Dérivés de spiro-pyrano-pyrazole |
EP2113501A1 (fr) * | 2008-04-25 | 2009-11-04 | Laboratorios Del. Dr. Esteve, S.A. | Pyrazoles de 5-Methyl-1-(naphthalen-2-YL)-1H- utiles en tant qu'inhibiteurs de récepteur sigma |
EP2335688A1 (fr) * | 2009-11-25 | 2011-06-22 | Laboratorios Del. Dr. Esteve, S.A. | Compositions pharmaceutiques comprenant des ligands du récepteur sigma |
EP2353598A1 (fr) * | 2010-02-04 | 2011-08-10 | Laboratorios Del. Dr. Esteve, S.A. | Ligands sigma pour utilisation dans la prévention et/ou le traitement de la douleur post-opératoire |
EP2395003A1 (fr) * | 2010-05-27 | 2011-12-14 | Laboratorios Del. Dr. Esteve, S.A. | Composés pyrazoliques en tant qu'inhibiteurs du récepteur sigma |
EP2415471A1 (fr) * | 2010-08-03 | 2012-02-08 | Laboratorios Del. Dr. Esteve, S.A. | Utilisation de ligands sigma dans l'hyperalgie induite par opioïdes |
-
2015
- 2015-12-14 MA MA041177A patent/MA41177A/fr unknown
- 2015-12-15 CA CA2968153A patent/CA2968153A1/fr not_active Abandoned
- 2015-12-15 TW TW104142067A patent/TW201630607A/zh unknown
- 2015-12-15 BR BR112017010845A patent/BR112017010845A2/pt not_active Application Discontinuation
- 2015-12-15 SG SG11201704530UA patent/SG11201704530UA/en unknown
- 2015-12-15 MX MX2017007792A patent/MX2017007792A/es unknown
- 2015-12-15 CN CN201580068190.3A patent/CN106999473A/zh active Pending
- 2015-12-15 RU RU2017125134A patent/RU2017125134A/ru not_active Application Discontinuation
- 2015-12-15 EP EP15813267.0A patent/EP3233078A1/fr not_active Withdrawn
- 2015-12-15 TN TN2017000201A patent/TN2017000201A1/en unknown
- 2015-12-15 JP JP2017528776A patent/JP2017537104A/ja active Pending
- 2015-12-15 KR KR1020177018377A patent/KR20170096130A/ko unknown
- 2015-12-15 AU AU2015365954A patent/AU2015365954A1/en not_active Abandoned
- 2015-12-15 US US15/532,168 patent/US20170273948A1/en not_active Abandoned
- 2015-12-15 WO PCT/EP2015/002524 patent/WO2016096125A1/fr active Application Filing
-
2017
- 2017-05-17 IL IL252339A patent/IL252339A0/en unknown
- 2017-05-17 PH PH12017500910A patent/PH12017500910A1/en unknown
- 2017-05-22 ZA ZA201703503A patent/ZA201703503B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA201703503B (en) | 2019-11-27 |
SG11201704530UA (en) | 2017-07-28 |
MX2017007792A (es) | 2017-09-18 |
IL252339A0 (en) | 2017-07-31 |
JP2017537104A (ja) | 2017-12-14 |
RU2017125134A (ru) | 2019-01-17 |
BR112017010845A2 (pt) | 2017-12-26 |
RU2017125134A3 (fr) | 2019-05-30 |
AU2015365954A1 (en) | 2017-06-08 |
PH12017500910A1 (en) | 2017-12-18 |
EP3233078A1 (fr) | 2017-10-25 |
WO2016096125A1 (fr) | 2016-06-23 |
TW201630607A (zh) | 2016-09-01 |
TN2017000201A1 (en) | 2018-10-19 |
CA2968153A1 (fr) | 2016-06-23 |
KR20170096130A (ko) | 2017-08-23 |
US20170273948A1 (en) | 2017-09-28 |
CN106999473A (zh) | 2017-08-01 |
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