DK1861100T3 - 3,11B-cis-dihydrotetrabenazin til behandling af en profilerativ sygdom eller en inflammation - Google Patents

3,11B-cis-dihydrotetrabenazin til behandling af en profilerativ sygdom eller en inflammation

Info

Publication number
DK1861100T3
DK1861100T3 DK06765213T DK06765213T DK1861100T3 DK 1861100 T3 DK1861100 T3 DK 1861100T3 DK 06765213 T DK06765213 T DK 06765213T DK 06765213 T DK06765213 T DK 06765213T DK 1861100 T3 DK1861100 T3 DK 1861100T3
Authority
DK
Denmark
Prior art keywords
dihydrotetrabenazine
cis
treatment
disease
profiler
Prior art date
Application number
DK06765213T
Other languages
English (en)
Inventor
Andrew John Duffield
Jean Elisabeth Yarrow
Original Assignee
Cambridge Lab Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Lab Ireland Ltd filed Critical Cambridge Lab Ireland Ltd
Application granted granted Critical
Publication of DK1861100T3 publication Critical patent/DK1861100T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK06765213T 2005-08-05 2006-08-04 3,11B-cis-dihydrotetrabenazin til behandling af en profilerativ sygdom eller en inflammation DK1861100T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0516168.2A GB0516168D0 (en) 2005-08-05 2005-08-05 Pharmaceutical compounds
PCT/GB2006/002909 WO2007017643A1 (en) 2005-08-05 2006-08-04 3 , llB-CIS-DIHYDROTETRABENAZINE FOR THE TREATMENT OF A PROLIFERATIVE DISEASE OR AN INFLAMMATION

Publications (1)

Publication Number Publication Date
DK1861100T3 true DK1861100T3 (da) 2008-12-15

Family

ID=34984180

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06765213T DK1861100T3 (da) 2005-08-05 2006-08-04 3,11B-cis-dihydrotetrabenazin til behandling af en profilerativ sygdom eller en inflammation

Country Status (24)

Country Link
US (1) US20090275605A1 (da)
EP (2) EP1964565A1 (da)
JP (1) JP2009503045A (da)
KR (1) KR20080033501A (da)
CN (1) CN101321528B (da)
AT (1) ATE412414T1 (da)
AU (1) AU2006277836B8 (da)
CA (1) CA2620952A1 (da)
CY (1) CY1108729T1 (da)
DE (1) DE602006003415D1 (da)
DK (1) DK1861100T3 (da)
ES (1) ES2317564T3 (da)
GB (1) GB0516168D0 (da)
HK (1) HK1111084A1 (da)
HR (1) HRP20090017T3 (da)
MX (1) MX2008001546A (da)
NZ (1) NZ566010A (da)
PL (1) PL1861100T3 (da)
PT (1) PT1861100E (da)
RS (1) RS50720B (da)
RU (1) RU2409364C2 (da)
SI (1) SI1861100T1 (da)
WO (1) WO2007017643A1 (da)
ZA (2) ZA200801170B (da)

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GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds
GB0514501D0 (en) * 2005-07-14 2005-08-24 Cambridge Lab Ireland Ltd Pharmaceutical compounds
JP5290185B2 (ja) 2006-11-08 2013-09-18 ニューロクライン バイオサイエンシーズ，インコーポレイテッド 置換３−イソブチル−９，１０−ジメトキシ−１，３，４，６，７，１１ｂ−ヘキサヒドロ−２Ｈ−ピリド［２，１−ａ］イソキノリン−２−オール化合物およびそれに関連する方法
GB0721669D0 (en) * 2007-11-02 2007-12-12 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB0810857D0 (en) * 2008-06-13 2008-07-23 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
US20110053866A1 (en) * 2008-08-12 2011-03-03 Biovail Laboratories International (Barbados) S.R.L. Pharmaceutical compositions
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
GB2463451A (en) * 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof
US20120003330A1 (en) 2010-06-01 2012-01-05 Auspex Pharmaceuticals, Inc. Benzoquinolone inhibitors of vmat2
CN102285984B (zh) * 2010-11-25 2012-10-10 江苏威凯尔医药科技有限公司 (2R,3R,11bR)-二氢丁苯那嗪及相关化合物的制备方法
EP3398602A1 (en) 2014-01-27 2018-11-07 Auspex Pharmaceuticals, Inc. Benzoquinoline inhibitors of vesicular monoamine transporter 2
MA41177A (fr) * 2014-12-15 2017-10-24 Esteve Labor Dr Utilisation de ligands des récepteurs sigma dans l'arthrose
WO2017164407A1 (ja) * 2016-03-25 2017-09-28 国立大学法人東北大学 免疫チェックポイント阻害作用を有するインドールアルカロイド型化合物
CN109283263B (zh) * 2017-07-21 2019-06-25 南京正大天晴制药有限公司 用于雷替曲塞合成质量控制的检测分析方法
CN109283279B (zh) * 2017-07-21 2019-11-01 南京正大天晴制药有限公司 通过高效液相色谱法分离测定雷替曲塞及其对映异构体的方法

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US3095419A (en) * 1963-06-25 Process for preparing z-oxo-j-
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US3053845A (en) * 1962-09-11 Benzofykedocolines
US3314966A (en) * 1967-04-18 Substituted benzo[a]quinolizines
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GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds
KR100682506B1 (ko) * 2005-01-18 2007-02-15 (주)젠크로스 프라지콴텔, 또는 이의 염을 포함하는 약학 조성물
GB0514501D0 (en) * 2005-07-14 2005-08-24 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB0810857D0 (en) * 2008-06-13 2008-07-23 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
US20110053866A1 (en) * 2008-08-12 2011-03-03 Biovail Laboratories International (Barbados) S.R.L. Pharmaceutical compositions
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
GB2463451A (en) * 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
EP1964565A1 (en) 2008-09-03
ES2317564T3 (es) 2009-04-16
EP1861100B1 (en) 2008-10-29
HRP20090017T3 (en) 2009-03-31
NZ566010A (en) 2010-05-28
PT1861100E (pt) 2008-12-26
CA2620952A1 (en) 2007-02-15
PL1861100T3 (pl) 2009-06-30
CN101321528B (zh) 2011-05-25
MX2008001546A (es) 2008-04-04
HK1111084A1 (en) 2008-08-01
AU2006277836B8 (en) 2011-12-08
CN101321528A (zh) 2008-12-10
ATE412414T1 (de) 2008-11-15
CY1108729T1 (el) 2014-04-09
DE602006003415D1 (de) 2008-12-11
SI1861100T1 (sl) 2009-04-30
RU2409364C2 (ru) 2011-01-20
GB0516168D0 (en) 2005-09-14
ZA200801170B (en) 2009-12-30
WO2007017643A1 (en) 2007-02-15
ZA200801171B (en) 2009-08-26
US20090275605A1 (en) 2009-11-05
RU2008108516A (ru) 2009-09-10
KR20080033501A (ko) 2008-04-16
JP2009503045A (ja) 2009-01-29
EP1861100A1 (en) 2007-12-05
RS50720B (sr) 2010-08-31
AU2006277836A1 (en) 2007-02-15
AU2006277836B2 (en) 2011-11-10

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