PL101880B1 - A method of producing new derivatives of erytromycin - Google Patents
A method of producing new derivatives of erytromycin Download PDFInfo
- Publication number
- PL101880B1 PL101880B1 PL1976188538A PL18853876A PL101880B1 PL 101880 B1 PL101880 B1 PL 101880B1 PL 1976188538 A PL1976188538 A PL 1976188538A PL 18853876 A PL18853876 A PL 18853876A PL 101880 B1 PL101880 B1 PL 101880B1
- Authority
- PL
- Poland
- Prior art keywords
- group
- erythromycylamine
- carbon atoms
- general formula
- condensation product
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2515075A DE2515075C2 (de) | 1975-04-07 | 1975-04-07 | Erythromycinderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE19762606030 DE2606030A1 (de) | 1976-02-14 | 1976-02-14 | Neue erythromycinderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL101880B1 true PL101880B1 (pl) | 1979-02-28 |
Family
ID=25768725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL1976188538A PL101880B1 (pl) | 1975-04-07 | 1976-04-06 | A method of producing new derivatives of erytromycin |
Country Status (29)
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4847242A (en) | 1985-03-12 | 1989-07-11 | Beecham Group P.L.C. | 11-ether derivatives of erythromycins |
| DE3524572A1 (de) * | 1985-07-10 | 1987-01-15 | Thomae Gmbh Dr K | Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung |
| US5110800A (en) * | 1986-02-18 | 1992-05-05 | Eli Lilly And Company | Derivatives of erythromycylamine |
| US4945080A (en) * | 1987-05-26 | 1990-07-31 | Eli Lilly And Company | Dirithromycin metabolite |
| US5075289A (en) * | 1988-06-07 | 1991-12-24 | Abbott Laboratories | 9-r-azacyclic erythromycin antibiotics |
| CA2096969C (en) * | 1990-11-28 | 2000-11-21 | Masato Kashimura | 6-0-methylerythromycin a derivatives |
| US5556839A (en) * | 1991-04-29 | 1996-09-17 | Eli Lilly And Company | Form II Dirithromycin |
| ZA922777B (en) * | 1991-04-29 | 1993-10-15 | Lilly Co Eli | Pharmaceutical formulation containing dirithromycin |
| CZ281664B6 (cs) * | 1991-09-30 | 1996-12-11 | Eli Lilly And Company Patent Division Lilly Corporate Center | Způsob jednostupňové přípravy dirithromycinu |
| US5527780A (en) * | 1992-11-05 | 1996-06-18 | Roussel Uclaf | Erythromycin derivatives |
| DE4410637C1 (de) * | 1994-03-26 | 1995-09-21 | Boehringer Ingelheim Vetmed | Injizierbare Lösungen von Dirithromycin |
| FR2718450B1 (fr) * | 1994-04-08 | 1997-01-10 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| FR2719587B1 (fr) * | 1994-05-03 | 1996-07-12 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| AU9645998A (en) * | 1997-10-29 | 1999-05-17 | Taisho Pharmaceutical Co., Ltd. | Erythromycin a derivatives |
| US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
| US6565882B2 (en) | 2000-02-24 | 2003-05-20 | Advancis Pharmaceutical Corp | Antibiotic composition with inhibitor |
| US20020068078A1 (en) | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
| US6541014B2 (en) | 2000-10-13 | 2003-04-01 | Advancis Pharmaceutical Corp. | Antiviral product, use and formulation thereof |
| US6436906B1 (en) | 2001-04-02 | 2002-08-20 | Enanta Pharmaceuticals, Inc. | 9-amino-14-membered macrolides derived from leucomycins |
| JP2006528190A (ja) | 2003-07-21 | 2006-12-14 | アドバンシス ファーマスーティカル コーポレイション | 抗生物質製剤、その使用法及び作成方法 |
| JP2006528185A (ja) | 2003-07-21 | 2006-12-14 | アドバンシス ファーマスーティカル コーポレイション | 抗生物質製剤、その使用法及び作成方法 |
| EP1648415A4 (en) | 2003-07-21 | 2011-11-16 | Middlebrook Pharmaceuticals Inc | ANTIBIOTIC PRODUCT, ITS USE AND FORMULATION |
| AU2004264939A1 (en) | 2003-08-11 | 2005-02-24 | Middlebrook Pharmaceuticals, Inc. | Robust pellet |
| WO2005016278A2 (en) | 2003-08-12 | 2005-02-24 | Advancis Pharmaceuticals Corporation | Antibiotic product, use and formulation thereof |
| AU2004270170B2 (en) * | 2003-08-29 | 2011-01-27 | Shionogi, Inc. | Antibiotic product, use and formulation thereof |
| EP1663169A4 (en) | 2003-09-15 | 2010-11-24 | Middlebrook Pharmaceuticals In | ANTIBIOTICS, ITS USE AND FORMULATION |
| AU2005269981A1 (en) | 2004-07-02 | 2006-02-09 | Bonck, John A | Tablet for pulsed delivery |
| US8357394B2 (en) | 2005-12-08 | 2013-01-22 | Shionogi Inc. | Compositions and methods for improved efficacy of penicillin-type antibiotics |
| US8778924B2 (en) | 2006-12-04 | 2014-07-15 | Shionogi Inc. | Modified release amoxicillin products |
| US8299052B2 (en) * | 2006-05-05 | 2012-10-30 | Shionogi Inc. | Pharmaceutical compositions and methods for improved bacterial eradication |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3660376A (en) * | 1970-09-30 | 1972-05-02 | Lilly Co Eli | N-arylidene erythromycylamines |
-
1976
- 1976-03-01 AT AT149976A patent/AT342770B/de not_active IP Right Cessation
- 1976-03-26 GR GR50399A patent/GR60374B/el unknown
- 1976-03-29 US US05/671,421 patent/US4048306A/en not_active Expired - Lifetime
- 1976-03-29 BG BG032727A patent/BG27380A3/xx unknown
- 1976-03-30 DK DK145276A patent/DK138656C/da not_active IP Right Cessation
- 1976-03-30 FI FI760845A patent/FI63244C/fi not_active IP Right Cessation
- 1976-04-02 CH CH417476A patent/CH621800A5/de not_active IP Right Cessation
- 1976-04-05 LU LU74702A patent/LU74702A1/xx unknown
- 1976-04-05 DD DD192208A patent/DD125218A5/xx unknown
- 1976-04-05 LU LU88563C patent/LU88563I2/fr unknown
- 1976-04-06 YU YU00876/76A patent/YU87676A/xx unknown
- 1976-04-06 GB GB13942/76A patent/GB1520963A/en not_active Expired
- 1976-04-06 NZ NZ180529A patent/NZ180529A/xx unknown
- 1976-04-06 RO RO85433A patent/RO68441B/ro unknown
- 1976-04-06 JP JP51038681A patent/JPS51128991A/ja active Granted
- 1976-04-06 CA CA249,700A patent/CA1060005A/en not_active Expired
- 1976-04-06 SU SU762343016A patent/SU682134A3/ru active
- 1976-04-06 NO NO761172A patent/NO141411C/no unknown
- 1976-04-06 SE SE7604052A patent/SE425566B/xx not_active IP Right Cessation
- 1976-04-06 MX MX000145U patent/MX3277E/es unknown
- 1976-04-06 PL PL1976188538A patent/PL101880B1/pl unknown
- 1976-04-06 NL NLAANVRAGE7603569,A patent/NL180107C/xx not_active IP Right Cessation
- 1976-04-06 AU AU12722/76A patent/AU498418B2/en not_active Expired
- 1976-04-06 IL IL49359A patent/IL49359A/xx unknown
- 1976-04-06 PT PT64977A patent/PT64977B/pt unknown
- 1976-04-06 CS CS762265A patent/CS196304B2/cs unknown
- 1976-04-06 HU HU76TO1026A patent/HU175186B/hu unknown
- 1976-04-06 ES ES446737A patent/ES446737A1/es not_active Expired
- 1976-04-07 FR FR7610144A patent/FR2306703A1/fr active Granted
- 1976-04-07 IE IE732/76A patent/IE43598B1/en not_active IP Right Cessation
-
1977
- 1977-03-05 ES ES456567A patent/ES456567A1/es not_active Expired
-
1980
- 1980-04-10 CH CH277580A patent/CH624413A5/de not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL101880B1 (pl) | A method of producing new derivatives of erytromycin | |
| JP3334980B2 (ja) | 新規なエリスロマイシン誘導体、それらの製造法及びそれらの薬剤としての用途 | |
| CS208798B2 (en) | Method of making the new derivatives of the n-substituted aziridin-2-carboxyl acid | |
| HU190541B (en) | Process for preparing disubstituted proline derivatives | |
| RU2129546C1 (ru) | 6,9-бис(аминозамещенные)-бензо(g)изохинолин-5,10-дионы, способ их получения, фармацевтическая композиция на их основе и способ ингибирования опухолей у млекопитающих | |
| AU759618B2 (en) | Tan-1057 derivatives | |
| JPS5973599A (ja) | Ｃ−２０−修飾マクロライド誘導体 | |
| WO2011013735A1 (ja) | 新規フラバノン誘導体 | |
| JPS60126284A (ja) | ピリドンカルボン酸誘導体およびその塩 | |
| US4080380A (en) | 2-Naphthyl-lower-alkylamines | |
| DE3880874T2 (de) | Morpholin-Derivate, deren Verfahren zur Herstellung und sie enthaltende pharmazeutische Zusammensetzungen. | |
| FR2461705A1 (fr) | Nouveaux derives de 1-(4-aminobenzyl)-2,3-dioxopiperazine et leurs sels d'addition d'acides, a action carcinostatique, et procedes pour les preparer | |
| JPH04244083A (ja) | 三環状ピリドン誘導体 | |
| US4578377A (en) | Derivatives of cephalosporins, their process of separation and antibiotic drugs containing the said derivatives | |
| CN111072740B (zh) | 红霉素a酮内酯类抗生素衍生物、其制备方法及应用 | |
| KR930003611B1 (ko) | 퀴놀론 카복실산 유도체의 제조방법 | |
| US4064270A (en) | N'-(Aminoacylaminophenyl) acetamidines | |
| JPS63166876A (ja) | ピリドンカルボン酸誘導体 | |
| JPS6229585A (ja) | エーテル化若しくはエステル化しうるジヒドロキシ基により位置２で置換された４―ｏｈキノリンカルボン酸の新規の誘導体、その製造方法、及び医薬としてのその使用 | |
| PL108305B1 (en) | Method of producing new erythromycin derivatives | |
| IE58497B1 (en) | New process for the preparation of derivatives of 4h-1, 2,4-triazole, the new triazoles so obtained, their use as medicaments and the pharmaceutical compositions containing them | |
| US3647779A (en) | Kasugamycin substituted antibacterial agents | |
| KR0147888B1 (ko) | 3-(1-아미노시클로알킬)피롤리딘 유도체 및 이의 제조방법 | |
| JPH0437073B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| HU179080B (en) | Process for producing new 1,4-dithiepino-square bracket-2,3-c-square bracket closed-pyrrole derivatives |