PH9669A - Imidazo-(5,1-f)-as-triazin-4(3h)-ones,their compositions and method of use - Google Patents

Imidazo-(5,1-f)-as-triazin-4(3h)-ones,their compositions and method of use

Info

Publication number
PH9669A
PH9669A PH14090*UA PH14090A PH9669A PH 9669 A PH9669 A PH 9669A PH 14090 A PH14090 A PH 14090A PH 9669 A PH9669 A PH 9669A
Authority
PH
Philippines
Prior art keywords
triazin
imidazo
ones
compositions
Prior art date
Application number
PH14090*UA
Other languages
English (en)
Inventor
L Lunts
A Oxford
S Garside
D Hartley
Original Assignee
L Lunts
A Oxford
S Garside
D Hartley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by L Lunts, A Oxford, S Garside, D Hartley filed Critical L Lunts
Publication of PH9669A publication Critical patent/PH9669A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH14090*UA 1971-11-19 1972-11-16 Imidazo-(5,1-f)-as-triazin-4(3h)-ones,their compositions and method of use PH9669A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5375071A GB1400999A (en) 1971-11-19 1971-11-19 Imidazo-triazine compounds and their use in therapeutic compositions

Publications (1)

Publication Number Publication Date
PH9669A true PH9669A (en) 1976-02-10

Family

ID=10468856

Family Applications (1)

Application Number Title Priority Date Filing Date
PH14090*UA PH9669A (en) 1971-11-19 1972-11-16 Imidazo-(5,1-f)-as-triazin-4(3h)-ones,their compositions and method of use

Country Status (18)

Country Link
US (1) US3840537A (enrdf_load_stackoverflow)
JP (1) JPS563873B2 (enrdf_load_stackoverflow)
AT (1) AT321923B (enrdf_load_stackoverflow)
AU (1) AU472127B2 (enrdf_load_stackoverflow)
BE (1) BE791025A (enrdf_load_stackoverflow)
CA (1) CA990292A (enrdf_load_stackoverflow)
CH (1) CH594671A5 (enrdf_load_stackoverflow)
DE (1) DE2255172A1 (enrdf_load_stackoverflow)
DK (1) DK138691B (enrdf_load_stackoverflow)
ES (1) ES408736A1 (enrdf_load_stackoverflow)
FR (1) FR2160407B1 (enrdf_load_stackoverflow)
GB (1) GB1400999A (enrdf_load_stackoverflow)
IE (1) IE37046B1 (enrdf_load_stackoverflow)
IL (1) IL40686A (enrdf_load_stackoverflow)
NL (1) NL7215646A (enrdf_load_stackoverflow)
PH (1) PH9669A (enrdf_load_stackoverflow)
SE (1) SE402915B (enrdf_load_stackoverflow)
ZA (1) ZA727532B (enrdf_load_stackoverflow)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1457873A (en) * 1973-01-04 1976-12-08 Allen & Hanburys Ltd Imidazotriazines
DE2314488C3 (de) * 1973-03-23 1979-01-04 C.H. Boehringer Sohn, 6507 Ingelheim 8-(2,6-Dichlorphenyl)-7-(4-chlorphenyl)-5-oxo-233,8-tetrahydro-imidazo [1,2-a] -s-triazin, Verfahren zu dessen Herstellung und dieses enthaltene Arzneimittel
DE2335193A1 (de) * 1973-07-11 1975-01-30 Hoechst Ag Bis-triazinobenzimidazole und ihre herstellung
US4115572A (en) * 1977-02-03 1978-09-19 American Cyanamid Company Imidazo-[1,5-d]-as-triazin-1(2H)-ones and method of ameliorating asthma
USRE30511E (en) * 1977-02-03 1981-02-10 American Cyanamid Company Imidazo[1,5-d]-as-triazine-4(3H)-ones and thiones
US4107307A (en) * 1977-02-03 1978-08-15 American Cyanamid Company Imidazo [1,5-d]-as-triazine-4(3H)-ones and thiones
DK109578A (da) * 1977-03-25 1978-09-26 Allen & Hanburys Ltd Fremgangsmaade til fremstilling af heterocycliske forbindelser
US4107308A (en) * 1977-10-18 1978-08-15 American Cyanamid Company Imidazo[1,5-d]-as-triazines
US4308384A (en) * 1978-09-18 1981-12-29 Glaxo Group Limited Production of triazinones
HU187474B (en) * 1981-11-18 1986-01-28 Gyogyszerkutato Intezet,Hu Process for producing new spiro-pyrazole-square bracket-1,5-d-square bracket closed-square bracket-1,2,4-square bracket closed-triazine derivatives
US4395547A (en) * 1982-02-10 1983-07-26 American Cyanamid Co. Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
US6624181B1 (en) * 1997-02-28 2003-09-23 Altana Pharma Ag Synergistic combination
US6362178B1 (en) 1997-11-12 2002-03-26 Bayer Aktiengesellschaft 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
DE19827640A1 (de) * 1998-06-20 1999-12-23 Bayer Ag 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone
EP1107747A4 (en) 1998-08-26 2003-04-23 Smithkline Beecham Corp COMPOSITIONS FOR THE TREATMENT OF PULMONARY DISEASES
EP2193808A1 (en) * 1999-08-21 2010-06-09 Nycomed GmbH Synergistic combination
JP4540295B2 (ja) * 2001-05-09 2010-09-08 バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト ２−フェニル置換イミダゾトリアジノンの新しい用途
GB0113343D0 (en) * 2001-06-01 2001-07-25 Bayer Ag Novel Heterocycles 2
GB0113344D0 (en) * 2001-06-01 2001-07-25 Bayer Ag Novel heterocycles 3
DE10135815A1 (de) 2001-07-23 2003-02-06 Bayer Ag Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
ES2326808T3 (es) * 2003-04-01 2009-10-20 Smithkline Beecham Corporation Compuestos de imidazotriazina para el tratamiento de enfermedades cancerosas.
TW201134828A (en) 2004-04-02 2011-10-16 Osi Pharm Inc 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors
DE102005001989A1 (de) * 2005-01-15 2006-07-20 Bayer Healthcare Ag Intravenöse Formulierungen von PDE-Inhibitoren
DE102005009241A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit kontrollierter Bioverfügbarkeit
DE102005009240A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
KR20080056250A (ko) * 2005-09-29 2008-06-20 바이엘 헬스케어 아게 비뇨기 장애의 치료를 위한 ｐｄｅ 억제제 및 이들의 조합
RS51843B (en) * 2005-11-17 2012-02-29 Osi Pharmaceuticals Llc. CONDENSED BICYCLIC m TOR INHIBITORS
US20100184769A1 (en) * 2007-06-13 2010-07-22 Bayer Schering Pharma Aktiengesellschaft Pde inhibitors for the treatment of hearing impairment
CN102405214A (zh) 2009-04-20 2012-04-04 Osi药物有限责任公司 C-吡嗪-甲胺的制备
CN103374002B (zh) * 2012-04-19 2015-07-15 山东轩竹医药科技有限公司 磷酸二酯酶-5抑制剂
JP2018508555A (ja) * 2015-03-16 2018-03-29 大日本住友製薬株式会社 二環性イミダゾロ誘導体
WO2017000276A1 (en) * 2015-07-01 2017-01-05 Merck Sharp & Dohme Corp. Bicyclic heterocyclic compounds as pde2 inhibitors
WO2017204316A1 (ja) * 2016-05-27 2017-11-30 塩野義製薬株式会社 ５－オキソ－１，２，４－トリアジン誘導体およびその医薬組成物

Also Published As

Publication number Publication date
CA990292A (en) 1976-06-01
AT321923B (de) 1975-04-25
GB1400999A (en) 1975-07-16
JPS4857993A (enrdf_load_stackoverflow) 1973-08-14
DK138691C (enrdf_load_stackoverflow) 1979-03-26
IE37046L (en) 1973-05-19
AU4819172A (en) 1974-05-16
FR2160407A1 (enrdf_load_stackoverflow) 1973-06-29
NL7215646A (enrdf_load_stackoverflow) 1973-05-22
ZA727532B (en) 1973-07-25
IE37046B1 (en) 1977-04-27
AU472127B2 (en) 1976-05-20
IL40686A (en) 1975-12-31
US3840537A (en) 1974-10-08
BE791025A (fr) 1973-05-07
JPS563873B2 (enrdf_load_stackoverflow) 1981-01-27
DE2255172A1 (de) 1973-05-24
FR2160407B1 (enrdf_load_stackoverflow) 1975-10-17
SE402915B (sv) 1978-07-24
DK138691B (da) 1978-10-16
ES408736A1 (es) 1976-03-01
IL40686A0 (en) 1972-12-29
CH594671A5 (enrdf_load_stackoverflow) 1978-01-13

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