ES408736A1 - Procedimiento para la preparacion de compuestos imidazo- triazinonas. - Google Patents
Procedimiento para la preparacion de compuestos imidazo- triazinonas.Info
- Publication number
- ES408736A1 ES408736A1 ES408736A ES408736A ES408736A1 ES 408736 A1 ES408736 A1 ES 408736A1 ES 408736 A ES408736 A ES 408736A ES 408736 A ES408736 A ES 408736A ES 408736 A1 ES408736 A1 ES 408736A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- group
- formula
- compounds
- represent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5375071A GB1400999A (en) | 1971-11-19 | 1971-11-19 | Imidazo-triazine compounds and their use in therapeutic compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
ES408736A1 true ES408736A1 (es) | 1976-03-01 |
Family
ID=10468856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES408736A Expired ES408736A1 (es) | 1971-11-19 | 1972-11-17 | Procedimiento para la preparacion de compuestos imidazo- triazinonas. |
Country Status (18)
Country | Link |
---|---|
US (1) | US3840537A (es) |
JP (1) | JPS563873B2 (es) |
AT (1) | AT321923B (es) |
AU (1) | AU472127B2 (es) |
BE (1) | BE791025A (es) |
CA (1) | CA990292A (es) |
CH (1) | CH594671A5 (es) |
DE (1) | DE2255172A1 (es) |
DK (1) | DK138691B (es) |
ES (1) | ES408736A1 (es) |
FR (1) | FR2160407B1 (es) |
GB (1) | GB1400999A (es) |
IE (1) | IE37046B1 (es) |
IL (1) | IL40686A (es) |
NL (1) | NL7215646A (es) |
PH (1) | PH9669A (es) |
SE (1) | SE402915B (es) |
ZA (1) | ZA727532B (es) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1457873A (en) * | 1973-01-04 | 1976-12-08 | Allen & Hanburys Ltd | Imidazotriazines |
DE2314488C3 (de) * | 1973-03-23 | 1979-01-04 | C.H. Boehringer Sohn, 6507 Ingelheim | 8-(2,6-Dichlorphenyl)-7-(4-chlorphenyl)-5-oxo-233,8-tetrahydro-imidazo [1,2-a] -s-triazin, Verfahren zu dessen Herstellung und dieses enthaltene Arzneimittel |
DE2335193A1 (de) * | 1973-07-11 | 1975-01-30 | Hoechst Ag | Bis-triazinobenzimidazole und ihre herstellung |
US4115572A (en) * | 1977-02-03 | 1978-09-19 | American Cyanamid Company | Imidazo-[1,5-d]-as-triazin-1(2H)-ones and method of ameliorating asthma |
US4107307A (en) * | 1977-02-03 | 1978-08-15 | American Cyanamid Company | Imidazo [1,5-d]-as-triazine-4(3H)-ones and thiones |
USRE30511E (en) * | 1977-02-03 | 1981-02-10 | American Cyanamid Company | Imidazo[1,5-d]-as-triazine-4(3H)-ones and thiones |
DK109578A (da) * | 1977-03-25 | 1978-09-26 | Allen & Hanburys Ltd | Fremgangsmaade til fremstilling af heterocycliske forbindelser |
US4107308A (en) * | 1977-10-18 | 1978-08-15 | American Cyanamid Company | Imidazo[1,5-d]-as-triazines |
US4308384A (en) * | 1978-09-18 | 1981-12-29 | Glaxo Group Limited | Production of triazinones |
HU187474B (en) * | 1981-11-18 | 1986-01-28 | Gyogyszerkutato Intezet,Hu | Process for producing new spiro-pyrazole-square bracket-1,5-d-square bracket closed-square bracket-1,2,4-square bracket closed-triazine derivatives |
US4395547A (en) * | 1982-02-10 | 1983-07-26 | American Cyanamid Co. | Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones |
AU622330B2 (en) * | 1989-06-23 | 1992-04-02 | Takeda Chemical Industries Ltd. | Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides |
US6624181B1 (en) * | 1997-02-28 | 2003-09-23 | Altana Pharma Ag | Synergistic combination |
US6362178B1 (en) * | 1997-11-12 | 2002-03-26 | Bayer Aktiengesellschaft | 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors |
DE19827640A1 (de) * | 1998-06-20 | 1999-12-23 | Bayer Ag | 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone |
HUP0103160A3 (en) | 1998-08-26 | 2002-11-28 | Smithkline Beecham Corp | Pharmaceutical compositions for treating pulmonary diseases containing pde4 inhibitor |
PT1212089E (pt) | 1999-08-21 | 2006-08-31 | Altana Pharma Ag | Combinacao sinergica de roflumilast e salmeterol |
EP1392314B1 (de) * | 2001-05-09 | 2006-12-20 | Bayer HealthCare AG | NEUE VERWENDUNG VON 2-[2-Ethoxy-5-(4-methyl-piperazin-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-on |
GB0113343D0 (en) * | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel Heterocycles 2 |
GB0113344D0 (en) * | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel heterocycles 3 |
DE10135815A1 (de) | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
DE10232113A1 (de) | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
WO2004087652A2 (en) * | 2003-04-01 | 2004-10-14 | Smithkline Beecham Corporation | Imidazotriazine compounds |
ATE433979T1 (de) | 2004-04-02 | 2009-07-15 | Osi Pharm Inc | Mit einem 6,6-bicyclischen ring substituierte heterobicyclische proteinkinaseinhibitoren |
DE102005001989A1 (de) * | 2005-01-15 | 2006-07-20 | Bayer Healthcare Ag | Intravenöse Formulierungen von PDE-Inhibitoren |
DE102005009240A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
DE102005009241A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit kontrollierter Bioverfügbarkeit |
US20090186896A1 (en) * | 2005-09-29 | 2009-07-23 | Bayer Healthcare Ag | PDE Inhibitors and Combinations Thereof for the Treatment of Urological Disorders |
WO2007061737A2 (en) * | 2005-11-17 | 2007-05-31 | Osi Pharmaceuticals, Inc. | FUSED BICYCLIC mTOR INHIBITORS |
JP2010532319A (ja) * | 2007-06-13 | 2010-10-07 | バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト | 聴覚障害の処置用のpde阻害剤 |
MX2011011025A (es) | 2009-04-20 | 2011-11-02 | Osi Pharmaceuticals Llc | Preparacion de c-piracin-metilaminas. |
CN103374002B (zh) * | 2012-04-19 | 2015-07-15 | 山东轩竹医药科技有限公司 | 磷酸二酯酶-5抑制剂 |
TW201639851A (zh) * | 2015-03-16 | 2016-11-16 | 大日本住友製藥股份有限公司 | 雙環咪唑衍生物 |
WO2017000276A1 (en) * | 2015-07-01 | 2017-01-05 | Merck Sharp & Dohme Corp. | Bicyclic heterocyclic compounds as pde2 inhibitors |
WO2017204316A1 (ja) * | 2016-05-27 | 2017-11-30 | 塩野義製薬株式会社 | 5-オキソ-1,2,4-トリアジン誘導体およびその医薬組成物 |
-
0
- BE BE791025D patent/BE791025A/xx unknown
-
1971
- 1971-11-19 GB GB5375071A patent/GB1400999A/en not_active Expired
-
1972
- 1972-10-23 DK DK525172AA patent/DK138691B/da unknown
- 1972-10-23 ZA ZA727532A patent/ZA727532B/xx unknown
- 1972-10-23 IE IE1433/72A patent/IE37046B1/xx unknown
- 1972-10-25 US US00300749A patent/US3840537A/en not_active Expired - Lifetime
- 1972-10-26 AU AU48191/72A patent/AU472127B2/en not_active Expired
- 1972-10-27 IL IL40686A patent/IL40686A/xx unknown
- 1972-11-01 CA CA155,720A patent/CA990292A/en not_active Expired
- 1972-11-06 SE SE7214358A patent/SE402915B/xx unknown
- 1972-11-08 FR FR7239498A patent/FR2160407B1/fr not_active Expired
- 1972-11-10 DE DE2255172A patent/DE2255172A1/de not_active Withdrawn
- 1972-11-16 PH PH14090*UA patent/PH9669A/en unknown
- 1972-11-16 CH CH1668372A patent/CH594671A5/xx not_active IP Right Cessation
- 1972-11-17 NL NL7215646A patent/NL7215646A/xx not_active Application Discontinuation
- 1972-11-17 JP JP11549572A patent/JPS563873B2/ja not_active Expired
- 1972-11-17 AT AT982372A patent/AT321923B/de not_active IP Right Cessation
- 1972-11-17 ES ES408736A patent/ES408736A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE2255172A1 (de) | 1973-05-24 |
GB1400999A (en) | 1975-07-16 |
FR2160407A1 (es) | 1973-06-29 |
FR2160407B1 (es) | 1975-10-17 |
CA990292A (en) | 1976-06-01 |
IE37046B1 (en) | 1977-04-27 |
DK138691B (da) | 1978-10-16 |
AU472127B2 (en) | 1976-05-20 |
IE37046L (en) | 1973-05-19 |
DK138691C (es) | 1979-03-26 |
JPS4857993A (es) | 1973-08-14 |
IL40686A (en) | 1975-12-31 |
AU4819172A (en) | 1974-05-16 |
SE402915B (sv) | 1978-07-24 |
AT321923B (de) | 1975-04-25 |
ZA727532B (en) | 1973-07-25 |
US3840537A (en) | 1974-10-08 |
IL40686A0 (en) | 1972-12-29 |
CH594671A5 (es) | 1978-01-13 |
NL7215646A (es) | 1973-05-22 |
JPS563873B2 (es) | 1981-01-27 |
BE791025A (fr) | 1973-05-07 |
PH9669A (en) | 1976-02-10 |
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