ZA727532B - Heterocyclic compounds - Google Patents
Heterocyclic compoundsInfo
- Publication number
- ZA727532B ZA727532B ZA727532A ZA727532A ZA727532B ZA 727532 B ZA727532 B ZA 727532B ZA 727532 A ZA727532 A ZA 727532A ZA 727532 A ZA727532 A ZA 727532A ZA 727532 B ZA727532 B ZA 727532B
- Authority
- ZA
- South Africa
- Prior art keywords
- heterocyclic compounds
- heterocyclic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5375071A GB1400999A (en) | 1971-11-19 | 1971-11-19 | Imidazo-triazine compounds and their use in therapeutic compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA727532B true ZA727532B (en) | 1973-07-25 |
Family
ID=10468856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA727532A ZA727532B (en) | 1971-11-19 | 1972-10-23 | Heterocyclic compounds |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3840537A (en) |
| JP (1) | JPS563873B2 (en) |
| AT (1) | AT321923B (en) |
| AU (1) | AU472127B2 (en) |
| BE (1) | BE791025A (en) |
| CA (1) | CA990292A (en) |
| CH (1) | CH594671A5 (en) |
| DE (1) | DE2255172A1 (en) |
| DK (1) | DK138691B (en) |
| ES (1) | ES408736A1 (en) |
| FR (1) | FR2160407B1 (en) |
| GB (1) | GB1400999A (en) |
| IE (1) | IE37046B1 (en) |
| IL (1) | IL40686A (en) |
| NL (1) | NL7215646A (en) |
| PH (1) | PH9669A (en) |
| SE (1) | SE402915B (en) |
| ZA (1) | ZA727532B (en) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1457873A (en) * | 1973-01-04 | 1976-12-08 | Allen & Hanburys Ltd | Imidazotriazines |
| DE2314488C3 (en) * | 1973-03-23 | 1979-01-04 | C.H. Boehringer Sohn, 6507 Ingelheim | 8- (2,6-Dichlorophenyl) -7- (4-chlorophenyl) -5-oxo-233,8-tetrahydro-imidazo [1,2-a] -s-triazine, process for its preparation and medicament containing it |
| DE2335193A1 (en) * | 1973-07-11 | 1975-01-30 | Hoechst Ag | BIS-TRIAZINOBENZIMIDAZOLE AND THEIR PRODUCTION |
| US4107307A (en) * | 1977-02-03 | 1978-08-15 | American Cyanamid Company | Imidazo [1,5-d]-as-triazine-4(3H)-ones and thiones |
| US4115572A (en) * | 1977-02-03 | 1978-09-19 | American Cyanamid Company | Imidazo-[1,5-d]-as-triazin-1(2H)-ones and method of ameliorating asthma |
| USRE30511E (en) * | 1977-02-03 | 1981-02-10 | American Cyanamid Company | Imidazo[1,5-d]-as-triazine-4(3H)-ones and thiones |
| DK109578A (en) * | 1977-03-25 | 1978-09-26 | Allen & Hanburys Ltd | PROCEDURE FOR MAKING HETEROCYCLIC COMPOUNDS |
| US4107308A (en) * | 1977-10-18 | 1978-08-15 | American Cyanamid Company | Imidazo[1,5-d]-as-triazines |
| US4308384A (en) * | 1978-09-18 | 1981-12-29 | Glaxo Group Limited | Production of triazinones |
| HU187474B (en) * | 1981-11-18 | 1986-01-28 | Gyogyszerkutato Intezet,Hu | Process for producing new spiro-pyrazole-square bracket-1,5-d-square bracket closed-square bracket-1,2,4-square bracket closed-triazine derivatives |
| US4395547A (en) * | 1982-02-10 | 1983-07-26 | American Cyanamid Co. | Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones |
| AU622330B2 (en) * | 1989-06-23 | 1992-04-02 | Takeda Chemical Industries Ltd. | Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides |
| US6624181B1 (en) * | 1997-02-28 | 2003-09-23 | Altana Pharma Ag | Synergistic combination |
| HU230154B1 (en) | 1997-11-12 | 2015-09-28 | Bayer Intellectual Property Gmbh | Process for the preparation of 2-phenyl substituted imidazotriazinones |
| DE19827640A1 (en) * | 1998-06-20 | 1999-12-23 | Bayer Ag | New imidazotriazine derivatives useful as smooth muscle relaxants for treating e.g. cardiovascular disorders, cerebrovascular disorders, or erectile dysfunction |
| WO2000012078A1 (en) | 1998-08-26 | 2000-03-09 | Smithkline Beecham Corporation | Therapies for treating pulmonary diseases |
| CA2715683A1 (en) * | 1999-08-21 | 2001-03-01 | Nycomed Gmbh | Synergistic combination |
| JP4540295B2 (en) * | 2001-05-09 | 2010-09-08 | バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト | New uses for 2-phenyl substituted imidazotriazinones |
| GB0113343D0 (en) * | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel Heterocycles 2 |
| GB0113344D0 (en) | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel heterocycles 3 |
| DE10135815A1 (en) | 2001-07-23 | 2003-02-06 | Bayer Ag | Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain |
| DE10232113A1 (en) | 2002-07-16 | 2004-01-29 | Bayer Ag | Medicinal products containing vardenafil hydrochloride trihydrate |
| WO2004087652A2 (en) * | 2003-04-01 | 2004-10-14 | Smithkline Beecham Corporation | Imidazotriazine compounds |
| CN102924458B (en) | 2004-04-02 | 2014-11-05 | Osi制药有限责任公司 | 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors |
| DE102005001989A1 (en) * | 2005-01-15 | 2006-07-20 | Bayer Healthcare Ag | Intravenous formulations of PDE inhibitors |
| DE102005009240A1 (en) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Dosage forms with improved pharmacokinetic properties |
| DE102005009241A1 (en) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Dosage forms with controlled bioavailability |
| SG166106A1 (en) * | 2005-09-29 | 2010-11-29 | Bayer Schering Pharma Ag | Pde inhibitors and combinations thereof for the treatment of urological disorders |
| EP2385053B1 (en) * | 2005-11-17 | 2013-10-02 | OSI Pharmaceuticals, Inc. | Intermediates for the preparation of fused bicyclic mTOR inhibitors |
| WO2008151734A1 (en) * | 2007-06-13 | 2008-12-18 | Bayer Schering Pharma Aktiengesellschaft | Pde inhibitors for the treatment of hearing impairment |
| CA2752826A1 (en) | 2009-04-20 | 2010-10-28 | OSI Pharmaceuticals, LLC | Preparation of c-pyrazine-methylamines |
| CN103374002B (en) * | 2012-04-19 | 2015-07-15 | 山东轩竹医药科技有限公司 | Phosphodiesterase-5 inhibitor |
| TW201639851A (en) * | 2015-03-16 | 2016-11-16 | 大日本住友製藥股份有限公司 | Bicyclic imidazolo derivative |
| WO2017000276A1 (en) * | 2015-07-01 | 2017-01-05 | Merck Sharp & Dohme Corp. | Bicyclic heterocyclic compounds as pde2 inhibitors |
| WO2017204316A1 (en) * | 2016-05-27 | 2017-11-30 | 塩野義製薬株式会社 | 5-oxo-1,2,4-triazine derivative, and pharmaceutical composition thereof |
-
0
- BE BE791025D patent/BE791025A/en unknown
-
1971
- 1971-11-19 GB GB5375071A patent/GB1400999A/en not_active Expired
-
1972
- 1972-10-23 DK DK525172AA patent/DK138691B/en unknown
- 1972-10-23 ZA ZA727532A patent/ZA727532B/en unknown
- 1972-10-23 IE IE1433/72A patent/IE37046B1/en unknown
- 1972-10-25 US US00300749A patent/US3840537A/en not_active Expired - Lifetime
- 1972-10-26 AU AU48191/72A patent/AU472127B2/en not_active Expired
- 1972-10-27 IL IL40686A patent/IL40686A/en unknown
- 1972-11-01 CA CA155,720A patent/CA990292A/en not_active Expired
- 1972-11-06 SE SE7214358A patent/SE402915B/en unknown
- 1972-11-08 FR FR7239498A patent/FR2160407B1/fr not_active Expired
- 1972-11-10 DE DE2255172A patent/DE2255172A1/en not_active Withdrawn
- 1972-11-16 PH PH14090*UA patent/PH9669A/en unknown
- 1972-11-16 CH CH1668372A patent/CH594671A5/xx not_active IP Right Cessation
- 1972-11-17 JP JP11549572A patent/JPS563873B2/ja not_active Expired
- 1972-11-17 NL NL7215646A patent/NL7215646A/xx not_active Application Discontinuation
- 1972-11-17 ES ES408736A patent/ES408736A1/en not_active Expired
- 1972-11-17 AT AT982372A patent/AT321923B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GB1400999A (en) | 1975-07-16 |
| AU472127B2 (en) | 1976-05-20 |
| BE791025A (en) | 1973-05-07 |
| AT321923B (en) | 1975-04-25 |
| CA990292A (en) | 1976-06-01 |
| FR2160407B1 (en) | 1975-10-17 |
| AU4819172A (en) | 1974-05-16 |
| CH594671A5 (en) | 1978-01-13 |
| NL7215646A (en) | 1973-05-22 |
| FR2160407A1 (en) | 1973-06-29 |
| DK138691B (en) | 1978-10-16 |
| PH9669A (en) | 1976-02-10 |
| IL40686A (en) | 1975-12-31 |
| DK138691C (en) | 1979-03-26 |
| IE37046B1 (en) | 1977-04-27 |
| US3840537A (en) | 1974-10-08 |
| JPS563873B2 (en) | 1981-01-27 |
| IL40686A0 (en) | 1972-12-29 |
| ES408736A1 (en) | 1976-03-01 |
| IE37046L (en) | 1973-05-19 |
| DE2255172A1 (en) | 1973-05-24 |
| JPS4857993A (en) | 1973-08-14 |
| SE402915B (en) | 1978-07-24 |
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