NL7215646A - - Google Patents

Info

Publication number
NL7215646A
NL7215646A NL7215646A NL7215646A NL7215646A NL 7215646 A NL7215646 A NL 7215646A NL 7215646 A NL7215646 A NL 7215646A NL 7215646 A NL7215646 A NL 7215646A NL 7215646 A NL7215646 A NL 7215646A
Authority
NL
Netherlands
Application number
NL7215646A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7215646A publication Critical patent/NL7215646A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines
    • C07D253/0651,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/071,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075Two hetero atoms, in positions 3 and 5
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D253/00Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/061,2,4-Triazines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
NL7215646A 1971-11-19 1972-11-17 NL7215646A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5375071A GB1400999A (en) 1971-11-19 1971-11-19 Imidazo-triazine compounds and their use in therapeutic compositions

Publications (1)

Publication Number Publication Date
NL7215646A true NL7215646A (en) 1973-05-22

Family

ID=10468856

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7215646A NL7215646A (en) 1971-11-19 1972-11-17

Country Status (18)

Country Link
US (1) US3840537A (en)
JP (1) JPS563873B2 (en)
AT (1) AT321923B (en)
AU (1) AU472127B2 (en)
BE (1) BE791025A (en)
CA (1) CA990292A (en)
CH (1) CH594671A5 (en)
DE (1) DE2255172A1 (en)
DK (1) DK138691B (en)
ES (1) ES408736A1 (en)
FR (1) FR2160407B1 (en)
GB (1) GB1400999A (en)
IE (1) IE37046B1 (en)
IL (1) IL40686A (en)
NL (1) NL7215646A (en)
PH (1) PH9669A (en)
SE (1) SE402915B (en)
ZA (1) ZA727532B (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1457873A (en) * 1973-01-04 1976-12-08 Allen & Hanburys Ltd Imidazotriazines
DE2314488C3 (en) * 1973-03-23 1979-01-04 C.H. Boehringer Sohn, 6507 Ingelheim 8- (2,6-Dichlorophenyl) -7- (4-chlorophenyl) -5-oxo-233,8-tetrahydro-imidazo [1,2-a] -s-triazine, process for its preparation and medicament containing it
DE2335193A1 (en) * 1973-07-11 1975-01-30 Hoechst Ag BIS-TRIAZINOBENZIMIDAZOLE AND THEIR PRODUCTION
US4107307A (en) * 1977-02-03 1978-08-15 American Cyanamid Company Imidazo [1,5-d]-as-triazine-4(3H)-ones and thiones
USRE30511E (en) * 1977-02-03 1981-02-10 American Cyanamid Company Imidazo[1,5-d]-as-triazine-4(3H)-ones and thiones
US4115572A (en) * 1977-02-03 1978-09-19 American Cyanamid Company Imidazo-[1,5-d]-as-triazin-1(2H)-ones and method of ameliorating asthma
DK109578A (en) * 1977-03-25 1978-09-26 Allen & Hanburys Ltd PROCEDURE FOR MAKING HETEROCYCLIC COMPOUNDS
US4107308A (en) * 1977-10-18 1978-08-15 American Cyanamid Company Imidazo[1,5-d]-as-triazines
US4308384A (en) * 1978-09-18 1981-12-29 Glaxo Group Limited Production of triazinones
HU187474B (en) * 1981-11-18 1986-01-28 Gyogyszerkutato Intezet,Hu Process for producing new spiro-pyrazole-square bracket-1,5-d-square bracket closed-square bracket-1,2,4-square bracket closed-triazine derivatives
US4395547A (en) * 1982-02-10 1983-07-26 American Cyanamid Co. Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones
AU622330B2 (en) * 1989-06-23 1992-04-02 Takeda Chemical Industries Ltd. Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides
US6624181B1 (en) * 1997-02-28 2003-09-23 Altana Pharma Ag Synergistic combination
DE19881732D2 (en) 1997-11-12 2000-08-24 Bayer Ag 2-phenyl-substituted imidazotriazinones as phosphodiesterase inhibitors
DE19827640A1 (en) * 1998-06-20 1999-12-23 Bayer Ag New imidazotriazine derivatives useful as smooth muscle relaxants for treating e.g. cardiovascular disorders, cerebrovascular disorders, or erectile dysfunction
EP1107747A4 (en) 1998-08-26 2003-04-23 Smithkline Beecham Corp Therapies for treating pulmonary diseases
AU777012B2 (en) * 1999-08-21 2004-09-30 Takeda Gmbh Synergistic combination of PDE inhibitors and beta 2 adrenoceptor agonist
JP4540295B2 (en) * 2001-05-09 2010-09-08 バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト New uses for 2-phenyl substituted imidazotriazinones
GB0113343D0 (en) * 2001-06-01 2001-07-25 Bayer Ag Novel Heterocycles 2
GB0113344D0 (en) * 2001-06-01 2001-07-25 Bayer Ag Novel heterocycles 3
DE10135815A1 (en) 2001-07-23 2003-02-06 Bayer Ag Use of imidazo-triazinone derivative phosphodiesterase 5 inhibitors e.g. for treatment of cardiac insufficiency, psoriasis, diabetes, cancer, glaucoma, bladder disease, Parkinson's disease or pain
DE10232113A1 (en) 2002-07-16 2004-01-29 Bayer Ag Medicinal products containing vardenafil hydrochloride trihydrate
EP1608656B1 (en) * 2003-04-01 2009-06-03 SmithKline Beecham Corporation Imidazotriazine compounds for the treatment of cancer diseases
EP2168968B1 (en) 2004-04-02 2017-08-23 OSI Pharmaceuticals, LLC 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors
DE102005001989A1 (en) * 2005-01-15 2006-07-20 Bayer Healthcare Ag Intravenous formulations of PDE inhibitors
DE102005009241A1 (en) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Dosage forms with controlled bioavailability
DE102005009240A1 (en) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Dosage forms with improved pharmacokinetic properties
BRPI0616633A2 (en) * 2005-09-29 2011-06-28 Bayer Healthcare Ag pde inhibitors and combinations thereof for the treatment of urological disorders
SI1951724T1 (en) * 2005-11-17 2011-09-30 Osi Pharmaceuticals Llc FUSED BICYCLIC mTOR INHIBITORS
EP2167057A1 (en) * 2007-06-13 2010-03-31 Bayer HealthCare AG Pde inhibitors for the treatment of hearing impairment
MX2011011025A (en) 2009-04-20 2011-11-02 Osi Pharmaceuticals Llc Preparation of c-pyrazine-methylamines.
CN103374002B (en) * 2012-04-19 2015-07-15 山东轩竹医药科技有限公司 Phosphodiesterase-5 inhibitor
US20180044343A1 (en) * 2015-03-16 2018-02-15 Sumitomo Dainippon Pharma Co., Ltd. Bicyclic imidazolo derivative
WO2017000276A1 (en) * 2015-07-01 2017-01-05 Merck Sharp & Dohme Corp. Bicyclic heterocyclic compounds as pde2 inhibitors
WO2017204316A1 (en) * 2016-05-27 2017-11-30 塩野義製薬株式会社 5-oxo-1,2,4-triazine derivative, and pharmaceutical composition thereof

Also Published As

Publication number Publication date
JPS563873B2 (en) 1981-01-27
IL40686A (en) 1975-12-31
JPS4857993A (en) 1973-08-14
IE37046L (en) 1973-05-19
AU472127B2 (en) 1976-05-20
GB1400999A (en) 1975-07-16
IL40686A0 (en) 1972-12-29
DK138691C (en) 1979-03-26
US3840537A (en) 1974-10-08
IE37046B1 (en) 1977-04-27
AT321923B (en) 1975-04-25
CA990292A (en) 1976-06-01
AU4819172A (en) 1974-05-16
FR2160407A1 (en) 1973-06-29
BE791025A (en) 1973-05-07
DE2255172A1 (en) 1973-05-24
DK138691B (en) 1978-10-16
ES408736A1 (en) 1976-03-01
PH9669A (en) 1976-02-10
FR2160407B1 (en) 1975-10-17
CH594671A5 (en) 1978-01-13
SE402915B (en) 1978-07-24
ZA727532B (en) 1973-07-25

Similar Documents

Publication Publication Date Title
DK138691C (en)
ATA136472A (en)
AR196074A1 (en)
AU2658571A (en)
AU2691671A (en)
AU2684071A (en)
AU2564071A (en)
AU2485671A (en)
AU2894671A (en)
AU2742671A (en)
AU2755871A (en)
AU2399971A (en)
AU2473671A (en)
AR199640Q (en)
AU2726271A (en)
AU2724971A (en)
AR202997Q (en)
AU2885171A (en)
AU2684171A (en)
AU2837671A (en)
AU2669471A (en)
AU2854371A (en)
AU2654071A (en)
AU2588771A (en)
AU2577671A (en)

Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed