AT321923B - Verfahren zur herstellung von neuen imidazotriazinonen - Google Patents
Verfahren zur herstellung von neuen imidazotriazinonenInfo
- Publication number
- AT321923B AT321923B AT982372A AT982372A AT321923B AT 321923 B AT321923 B AT 321923B AT 982372 A AT982372 A AT 982372A AT 982372 A AT982372 A AT 982372A AT 321923 B AT321923 B AT 321923B
- Authority
- AT
- Austria
- Prior art keywords
- imidazotriazinones
- producing new
- producing
- new
- new imidazotriazinones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5375071A GB1400999A (en) | 1971-11-19 | 1971-11-19 | Imidazo-triazine compounds and their use in therapeutic compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT321923B true AT321923B (de) | 1975-04-25 |
Family
ID=10468856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT982372A AT321923B (de) | 1971-11-19 | 1972-11-17 | Verfahren zur herstellung von neuen imidazotriazinonen |
Country Status (18)
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1457873A (en) * | 1973-01-04 | 1976-12-08 | Allen & Hanburys Ltd | Imidazotriazines |
| DE2314488C3 (de) * | 1973-03-23 | 1979-01-04 | C.H. Boehringer Sohn, 6507 Ingelheim | 8-(2,6-Dichlorphenyl)-7-(4-chlorphenyl)-5-oxo-233,8-tetrahydro-imidazo [1,2-a] -s-triazin, Verfahren zu dessen Herstellung und dieses enthaltene Arzneimittel |
| DE2335193A1 (de) * | 1973-07-11 | 1975-01-30 | Hoechst Ag | Bis-triazinobenzimidazole und ihre herstellung |
| USRE30511E (en) * | 1977-02-03 | 1981-02-10 | American Cyanamid Company | Imidazo[1,5-d]-as-triazine-4(3H)-ones and thiones |
| US4115572A (en) * | 1977-02-03 | 1978-09-19 | American Cyanamid Company | Imidazo-[1,5-d]-as-triazin-1(2H)-ones and method of ameliorating asthma |
| US4107307A (en) * | 1977-02-03 | 1978-08-15 | American Cyanamid Company | Imidazo [1,5-d]-as-triazine-4(3H)-ones and thiones |
| DK109578A (da) * | 1977-03-25 | 1978-09-26 | Allen & Hanburys Ltd | Fremgangsmaade til fremstilling af heterocycliske forbindelser |
| US4107308A (en) * | 1977-10-18 | 1978-08-15 | American Cyanamid Company | Imidazo[1,5-d]-as-triazines |
| US4308384A (en) * | 1978-09-18 | 1981-12-29 | Glaxo Group Limited | Production of triazinones |
| HU187474B (en) * | 1981-11-18 | 1986-01-28 | Gyogyszerkutato Intezet,Hu | Process for producing new spiro-pyrazole-square bracket-1,5-d-square bracket closed-square bracket-1,2,4-square bracket closed-triazine derivatives |
| US4395547A (en) * | 1982-02-10 | 1983-07-26 | American Cyanamid Co. | Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones |
| AU622330B2 (en) * | 1989-06-23 | 1992-04-02 | Takeda Chemical Industries Ltd. | Condensed heterocyclic compounds having a nitrogen atom in the bridgehead for use as fungicides |
| US6624181B1 (en) * | 1997-02-28 | 2003-09-23 | Altana Pharma Ag | Synergistic combination |
| CZ301911B6 (cs) * | 1997-11-12 | 2010-07-28 | Bayer Schering Pharma Aktiengesellschaft | 2-Fenylsubstituované imidazotriazinony, zpusob jejich výroby, léciva tyto látky obsahující a jejich použití |
| DE19827640A1 (de) * | 1998-06-20 | 1999-12-23 | Bayer Ag | 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone |
| AU754379B2 (en) | 1998-08-26 | 2002-11-14 | Smithkline Beecham Corporation | Therapies for treating pulmonary diseases |
| JP5038568B2 (ja) * | 1999-08-21 | 2012-10-03 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 協力剤の組合せ物 |
| EP1392314B1 (de) * | 2001-05-09 | 2006-12-20 | Bayer HealthCare AG | NEUE VERWENDUNG VON 2-[2-Ethoxy-5-(4-methyl-piperazin-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-on |
| GB0113343D0 (en) * | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel Heterocycles 2 |
| GB0113344D0 (en) * | 2001-06-01 | 2001-07-25 | Bayer Ag | Novel heterocycles 3 |
| DE10135815A1 (de) | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
| DE10232113A1 (de) * | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
| DE602004021363D1 (de) * | 2003-04-01 | 2009-07-16 | Smithkline Beecham Corp | Imidazotriazin verbindungen zur behandlung von krebserkrankungen |
| CN1960993A (zh) | 2004-04-02 | 2007-05-09 | Osi制药公司 | 6,6－双环取代的杂双环蛋白激酶抑制剂 |
| DE102005001989A1 (de) * | 2005-01-15 | 2006-07-20 | Bayer Healthcare Ag | Intravenöse Formulierungen von PDE-Inhibitoren |
| DE102005009241A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit kontrollierter Bioverfügbarkeit |
| DE102005009240A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
| WO2007039075A2 (en) * | 2005-09-29 | 2007-04-12 | Bayer Healthcare Ag | Pde inhibitors and combinations thereof for the treatment of urological disorders |
| RS51843B (en) * | 2005-11-17 | 2012-02-29 | Osi Pharmaceuticals Llc. | CONDENSED BICYCLIC m TOR INHIBITORS |
| WO2008151734A1 (en) * | 2007-06-13 | 2008-12-18 | Bayer Schering Pharma Aktiengesellschaft | Pde inhibitors for the treatment of hearing impairment |
| WO2010123792A1 (en) | 2009-04-20 | 2010-10-28 | Osi Pharmaceuticals, Inc. | Preparation of c-pyrazine-methylamines |
| CN103374002B (zh) * | 2012-04-19 | 2015-07-15 | 山东轩竹医药科技有限公司 | 磷酸二酯酶-5抑制剂 |
| JP2018508555A (ja) * | 2015-03-16 | 2018-03-29 | 大日本住友製薬株式会社 | 二環性イミダゾロ誘導体 |
| WO2017000276A1 (en) * | 2015-07-01 | 2017-01-05 | Merck Sharp & Dohme Corp. | Bicyclic heterocyclic compounds as pde2 inhibitors |
| WO2017204316A1 (ja) * | 2016-05-27 | 2017-11-30 | 塩野義製薬株式会社 | ５－オキソ－１，２，４－トリアジン誘導体およびその医薬組成物 |
-
0
- BE BE791025D patent/BE791025A/xx unknown
-
1971
- 1971-11-19 GB GB5375071A patent/GB1400999A/en not_active Expired
-
1972
- 1972-10-23 DK DK525172AA patent/DK138691B/da unknown
- 1972-10-23 ZA ZA727532A patent/ZA727532B/xx unknown
- 1972-10-23 IE IE1433/72A patent/IE37046B1/xx unknown
- 1972-10-25 US US00300749A patent/US3840537A/en not_active Expired - Lifetime
- 1972-10-26 AU AU48191/72A patent/AU472127B2/en not_active Expired
- 1972-10-27 IL IL40686A patent/IL40686A/xx unknown
- 1972-11-01 CA CA155,720A patent/CA990292A/en not_active Expired
- 1972-11-06 SE SE7214358A patent/SE402915B/xx unknown
- 1972-11-08 FR FR7239498A patent/FR2160407B1/fr not_active Expired
- 1972-11-10 DE DE2255172A patent/DE2255172A1/de not_active Withdrawn
- 1972-11-16 PH PH14090*UA patent/PH9669A/en unknown
- 1972-11-16 CH CH1668372A patent/CH594671A5/xx not_active IP Right Cessation
- 1972-11-17 AT AT982372A patent/AT321923B/de not_active IP Right Cessation
- 1972-11-17 ES ES408736A patent/ES408736A1/es not_active Expired
- 1972-11-17 JP JP11549572A patent/JPS563873B2/ja not_active Expired
- 1972-11-17 NL NL7215646A patent/NL7215646A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CH594671A5 (enrdf_load_stackoverflow) | 1978-01-13 |
| JPS563873B2 (enrdf_load_stackoverflow) | 1981-01-27 |
| GB1400999A (en) | 1975-07-16 |
| PH9669A (en) | 1976-02-10 |
| ZA727532B (en) | 1973-07-25 |
| JPS4857993A (enrdf_load_stackoverflow) | 1973-08-14 |
| ES408736A1 (es) | 1976-03-01 |
| FR2160407B1 (enrdf_load_stackoverflow) | 1975-10-17 |
| SE402915B (sv) | 1978-07-24 |
| IE37046L (en) | 1973-05-19 |
| NL7215646A (enrdf_load_stackoverflow) | 1973-05-22 |
| IE37046B1 (en) | 1977-04-27 |
| AU4819172A (en) | 1974-05-16 |
| AU472127B2 (en) | 1976-05-20 |
| CA990292A (en) | 1976-06-01 |
| IL40686A (en) | 1975-12-31 |
| BE791025A (fr) | 1973-05-07 |
| DK138691B (da) | 1978-10-16 |
| DK138691C (enrdf_load_stackoverflow) | 1979-03-26 |
| DE2255172A1 (de) | 1973-05-24 |
| IL40686A0 (en) | 1972-12-29 |
| FR2160407A1 (enrdf_load_stackoverflow) | 1973-06-29 |
| US3840537A (en) | 1974-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |