PH24719A - Cephem compound, pharmaceutical composition containing said compound and method of use thereof - Google Patents
Cephem compound, pharmaceutical composition containing said compound and method of use thereofInfo
- Publication number
- PH24719A PH24719A PH37528A PH37528A PH24719A PH 24719 A PH24719 A PH 24719A PH 37528 A PH37528 A PH 37528A PH 37528 A PH37528 A PH 37528A PH 24719 A PH24719 A PH 24719A
- Authority
- PH
- Philippines
- Prior art keywords
- compound
- pharmaceutical composition
- composition containing
- cephem
- cephem compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878721568A GB8721568D0 (en) | 1987-09-14 | 1987-09-14 | Cephem compounds |
GB888815361A GB8815361D0 (en) | 1988-06-28 | 1988-06-28 | New cephem compound & process for preparation thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
PH24719A true PH24719A (en) | 1990-10-01 |
Family
ID=26292732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH37528A PH24719A (en) | 1987-09-14 | 1988-09-09 | Cephem compound, pharmaceutical composition containing said compound and method of use thereof |
Country Status (22)
Country | Link |
---|---|
US (1) | US4952578A (de) |
EP (1) | EP0307804B1 (de) |
JP (1) | JPH01151589A (de) |
KR (1) | KR0133560B1 (de) |
CN (1) | CN1024669C (de) |
AU (1) | AU617358B2 (de) |
CA (1) | CA1338842C (de) |
DE (1) | DE3885688T2 (de) |
DK (1) | DK509988A (de) |
ES (1) | ES2061581T3 (de) |
FI (1) | FI92322C (de) |
HK (1) | HK18396A (de) |
HU (1) | HU211830A9 (de) |
IE (1) | IE63094B1 (de) |
IL (1) | IL87731A (de) |
NO (1) | NO171853C (de) |
NZ (1) | NZ226143A (de) |
OA (1) | OA09014A (de) |
PH (1) | PH24719A (de) |
PT (1) | PT88481B (de) |
RU (1) | RU1787158C (de) |
UA (1) | UA41865C2 (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5194432A (en) * | 1985-11-22 | 1993-03-16 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
CA1293719C (en) * | 1986-09-22 | 1991-12-31 | Takao Takaya | Cephem compounds and processes for preparation thereof |
US5162520A (en) * | 1986-09-22 | 1992-11-10 | Fujisawa Pharmaceutical Co., Ltd. | Intermediates for cephem compounds |
US5663163A (en) * | 1987-09-07 | 1997-09-02 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds and processes for preparation thereof |
GB8905301D0 (en) * | 1989-03-08 | 1989-04-19 | Fujisawa Pharmaceutical Co | New cephem compound and a process for preparation thereof |
EP0517041A1 (de) * | 1991-06-07 | 1992-12-09 | Fujisawa Pharmaceutical Co., Ltd. | Cephemverbindungen |
MXPA03010002A (es) * | 2001-05-01 | 2004-06-30 | Fujisawa Pharmaceutical Co | Compuestos de cefemo. |
KR100463920B1 (ko) * | 2002-10-18 | 2004-12-30 | 제일약품주식회사 | 신규 세프디토렌 피복실 메지틸렌 설폰산염 및 그 제조방법 |
ATE368042T1 (de) * | 2002-10-30 | 2007-08-15 | Astellas Pharma Inc | Cephemverbindungen |
AU2003902380A0 (en) * | 2003-05-16 | 2003-06-05 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
WO2005027909A1 (en) * | 2003-09-18 | 2005-03-31 | Astellas Pharma Inc. | Cephem compounds |
CN1321109C (zh) * | 2003-11-07 | 2007-06-13 | 天津药物研究院 | 一种头孢烯类鎓盐化合物及其制备方法和以该化合物合成硫酸头孢吡唑的方法 |
CN101747348B (zh) * | 2008-12-11 | 2013-02-06 | 石药集团中奇制药技术(石家庄)有限公司 | 一种硫酸头孢噻利晶型及其制备方法 |
CN101781318B (zh) * | 2010-02-26 | 2013-07-31 | 烟台宝华生物技术有限公司 | 头孢母核衍生化合物、由其制备的头孢烯类鎓盐化合物及采用其制备硫酸头孢吡唑的方法 |
CN101830913B (zh) * | 2010-04-09 | 2012-10-31 | 烟台宝华生物技术有限公司 | 头孢母核衍生化合物、由其制备的头孢烯类鎓盐化合物及采用其制备硫酸头孢吡唑的方法 |
CN101993450B (zh) * | 2010-11-03 | 2011-11-30 | 湖南欧亚生物有限公司 | 一种硫酸头孢噻利的制备方法 |
CN102336771A (zh) * | 2011-07-11 | 2012-02-01 | 珠海联邦制药股份有限公司 | 一种硫酸头孢噻利中间体的制备方法 |
EA028342B1 (ru) | 2011-09-09 | 2017-11-30 | Мерк Шарп И Доум Корп. | Способы лечения пневмонии |
US8809314B1 (en) | 2012-09-07 | 2014-08-19 | Cubist Pharmacueticals, Inc. | Cephalosporin compound |
US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
CN102875572B (zh) * | 2012-10-26 | 2014-07-30 | 四川科伦药物研究有限公司 | 一种硫酸头孢噻利中间体的精制方法 |
NZ700372A (en) | 2013-03-15 | 2016-01-29 | Merck Sharp & Dohme | Ceftolozane antibiotic compositions |
US20140274997A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Cephalosporin pharmaceutical compositions |
US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
EP3043797B1 (de) | 2013-09-09 | 2020-04-08 | Merck Sharp & Dohme Corp. | Behandlung von infektionen mit ceftolozan/tazobactam bei personen mit beeinträchtigter nierenfunktion |
US8906898B1 (en) | 2013-09-27 | 2014-12-09 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2760484C2 (de) * | 1976-04-14 | 1992-12-03 | Takeda Chemical Industries, Ltd., Osaka, Jp | |
GB2037281B (en) * | 1978-11-15 | 1983-01-19 | Glaxo Group Ltd | 7( -(2-amino-4-thiozolyl)-2-hydroximino-acetanuds)-cephalosporins |
DE3279470D1 (en) * | 1981-04-03 | 1989-04-06 | Fujisawa Pharmaceutical Co | New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds |
JPS584789A (ja) * | 1981-04-03 | 1983-01-11 | Fujisawa Pharmaceut Co Ltd | 新規セフエム化合物およびその製造法 |
US4401668A (en) * | 1981-10-02 | 1983-08-30 | Eli Lilly And Company | Pyrazinium substituted cephalosporins |
ATE82976T1 (de) * | 1985-09-03 | 1992-12-15 | Otsuka Kagaku Kk | Cephalosporinderivate. |
DE3539901A1 (de) * | 1985-11-11 | 1987-05-14 | Hoechst Ag | Cephalosporinderivate und verfahren zu ihrer herstellung |
CN86107947A (zh) * | 1985-11-22 | 1987-05-27 | 藤沢药品工业株式会社 | 新的头孢烯化合物及其制备方法 |
-
1988
- 1988-09-06 IE IE269288A patent/IE63094B1/en not_active IP Right Cessation
- 1988-09-07 US US07/241,419 patent/US4952578A/en not_active Expired - Lifetime
- 1988-09-09 PH PH37528A patent/PH24719A/en unknown
- 1988-09-09 DE DE88114722T patent/DE3885688T2/de not_active Expired - Fee Related
- 1988-09-09 IL IL87731A patent/IL87731A/xx not_active IP Right Cessation
- 1988-09-09 EP EP88114722A patent/EP0307804B1/de not_active Expired - Lifetime
- 1988-09-09 ES ES88114722T patent/ES2061581T3/es not_active Expired - Lifetime
- 1988-09-12 KR KR1019880011743A patent/KR0133560B1/ko not_active IP Right Cessation
- 1988-09-12 NZ NZ226143A patent/NZ226143A/en unknown
- 1988-09-13 CN CN88106644A patent/CN1024669C/zh not_active Expired - Fee Related
- 1988-09-13 RU SU4356636A patent/RU1787158C/ru active
- 1988-09-13 FI FI884193A patent/FI92322C/fi not_active IP Right Cessation
- 1988-09-13 PT PT88481A patent/PT88481B/pt not_active IP Right Cessation
- 1988-09-13 NO NO884058A patent/NO171853C/no not_active IP Right Cessation
- 1988-09-13 DK DK509988A patent/DK509988A/da not_active Application Discontinuation
- 1988-09-13 CA CA000577194A patent/CA1338842C/en not_active Expired - Fee Related
- 1988-09-14 JP JP63233183A patent/JPH01151589A/ja active Granted
- 1988-09-14 OA OA59431A patent/OA09014A/xx unknown
- 1988-09-14 AU AU22271/88A patent/AU617358B2/en not_active Ceased
-
1992
- 1992-02-24 UA UA5010902A patent/UA41865C2/uk unknown
-
1995
- 1995-06-22 HU HU95P/P00350P patent/HU211830A9/hu unknown
-
1996
- 1996-02-01 HK HK18396A patent/HK18396A/xx not_active IP Right Cessation
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