PH23404A - Q-substituted tetrahydropyridine oxine cholinergic agents - Google Patents
Q-substituted tetrahydropyridine oxine cholinergic agentsInfo
- Publication number
- PH23404A PH23404A PH36177A PH36177A PH23404A PH 23404 A PH23404 A PH 23404A PH 36177 A PH36177 A PH 36177A PH 36177 A PH36177 A PH 36177A PH 23404 A PH23404 A PH 23404A
- Authority
- PH
- Philippines
- Prior art keywords
- oxine
- cholinergic agents
- substituted tetrahydropyridine
- tetrahydropyridine
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/939,507 US4710508A (en) | 1986-12-08 | 1986-12-08 | O-substituted tetrahydropyridine oxime cholinergic agents |
US07/091,893 US4786648A (en) | 1986-12-08 | 1987-09-04 | O-substituted tetrahydropyridine oxime cholinergic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
PH23404A true PH23404A (en) | 1989-07-26 |
Family
ID=26784455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH36177A PH23404A (en) | 1986-12-08 | 1987-12-07 | Q-substituted tetrahydropyridine oxine cholinergic agents |
Country Status (11)
Country | Link |
---|---|
US (1) | US4786648A (pt) |
EP (1) | EP0271798B1 (pt) |
KR (1) | KR960000072B1 (pt) |
AU (1) | AU607442B2 (pt) |
DE (1) | DE3785312T2 (pt) |
DK (1) | DK638487A (pt) |
FI (1) | FI85467C (pt) |
NO (1) | NO172045C (pt) |
NZ (1) | NZ222756A (pt) |
PH (1) | PH23404A (pt) |
PT (1) | PT86311B (pt) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL81610A (en) * | 1986-02-27 | 1990-12-23 | Roussel Uclaf | Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them |
US5219873A (en) * | 1987-04-24 | 1993-06-15 | Roussel Uclaf | Compounds of 1,2,5,6-tetrahydropyridine which are useful as cholinergic agents |
IT1203971B (it) * | 1987-04-24 | 1989-02-23 | Roussel Maestretti Spa | Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti |
IT1222526B (it) * | 1987-08-21 | 1990-09-05 | Roussel Maestretti Spa | Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali |
US5231107A (en) * | 1987-08-21 | 1993-07-27 | Roussel Uclaf | Derivatives of the oxime of 1,2,5,6-tetrahydropyridine 3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them |
IE63906B1 (en) * | 1987-11-13 | 1995-06-14 | Novo Nordisk As | Azabicyclic compounds and their preparation and use |
US5110828A (en) * | 1988-04-15 | 1992-05-05 | Beecham Group P.L.C. | Azabicyclo oxime derivatives |
DK0392803T3 (da) * | 1989-04-13 | 2004-10-18 | Beecham Group Plc | Hidtil ukendte forbindelser |
US5278170A (en) * | 1989-04-13 | 1994-01-11 | Beecham Group P.L.C. | Azabicylo oxime compounds |
IT1240603B (it) * | 1990-03-14 | 1993-12-17 | Roussel Maestretti Spa | Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale |
IT1241138B (it) * | 1990-05-15 | 1993-12-29 | Roussel Pharma | Derivati dell'ossina della 1,2,5,6- tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali |
EP0544773B1 (en) * | 1990-08-24 | 1998-03-18 | Beecham Group Plc | Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them |
GB9019095D0 (en) * | 1990-09-01 | 1990-10-17 | Beecham Group Plc | Novel compounds |
JPH06501933A (ja) * | 1990-10-12 | 1994-03-03 | ビーチャム・グループ・パブリック・リミテッド・カンパニー | 1,2,5,6−テトラヒドロピリジン・オキシム誘導体 |
US5175166A (en) * | 1991-08-27 | 1992-12-29 | The University Of Toledo | Muscarinic agonists |
WO1993011767A1 (en) * | 1991-12-18 | 1993-06-24 | Warner-Lambert Company | Transdermal delivery of (e)-1,2,5,6-tetrahydro-1-methyl-3-pyridine-carboxaldehyde-o-methyloxine hcl and related compounds in the treatment of cognitive disorders and for analgesia |
ZA931109B (en) * | 1992-03-04 | 1993-09-22 | Akzo Nv | Tetrahydropyrimidine derivatives. |
US5208343A (en) * | 1992-03-24 | 1993-05-04 | Warner-Lambert Company | Tetrahydropyridine oxime compounds |
WO1994007493A1 (en) * | 1992-10-06 | 1994-04-14 | Warner-Lambert Company | Stabilized compositions containing 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxyaldehyde-o-methyl-oxime |
ZA937382B (en) * | 1992-10-06 | 1994-04-29 | Warner Lambert Co | Novel composition for peroral therapy of cognitionimpairment and a process therefor |
WO1994012480A1 (en) * | 1992-11-27 | 1994-06-09 | Akzo Nobel N.V. | 1,3-diazacycloalkyl oxime derivatives |
US5424301A (en) * | 1993-02-01 | 1995-06-13 | Warner-Lambert Company | Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents |
US5362860A (en) * | 1993-02-01 | 1994-11-08 | Warner-Lambert Company | Neutral stabilization complex for CI-979 HCl, a cognition activator |
US5618818A (en) * | 1996-03-20 | 1997-04-08 | The University Of Toledo | Muscarinic agonist compounds |
ATE445838T1 (de) | 2001-07-25 | 2009-10-15 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
WO2004101422A2 (en) * | 2003-05-13 | 2004-11-25 | Oasis Corporation | Combined water cooler and refrigerator unit |
EP2671508B1 (en) | 2005-04-28 | 2020-09-16 | Proteus Digital Health, Inc. | Pharma-informatics system |
EP2275095A3 (en) * | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
EP2377530A3 (en) | 2005-10-21 | 2012-06-20 | Braincells, Inc. | Modulation of neurogenesis by PDE inhibition |
EP2314289A1 (en) | 2005-10-31 | 2011-04-27 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
WO2007075297A2 (en) * | 2005-12-27 | 2007-07-05 | University Of Toledo | Muscarinic agonists and methods of use thereof |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
WO2007134077A2 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
CA2651813A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
AU2007292848A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
CA2663377A1 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
WO2009140483A1 (en) | 2008-05-15 | 2009-11-19 | University Of Toledo | Muscarinic agonists as cognitive enhancers |
HUE059078T2 (hu) | 2009-02-20 | 2022-10-28 | Enhanx Biopharm Inc | Glutation-alapú hatóanyagszállító rendszer |
US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
JP2012526144A (ja) | 2009-05-06 | 2012-10-25 | ラボラトリー スキン ケア インコーポレイテッド | 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法 |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
WO2012149524A1 (en) | 2011-04-29 | 2012-11-01 | The University Of Toledo | Muscarinic agonists as enhancers of working memory and cognitive flexibility |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB889074A (en) * | 1959-02-12 | 1962-02-07 | Ciba Ltd | New pyridine derivatives and process for their manufacture |
FR1258847A (fr) * | 1960-02-12 | 1961-04-21 | Ciba Geigy | Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine |
JPS511638A (ja) * | 1974-06-27 | 1976-01-08 | Fujisawa Pharmaceutical Co | Shokubutsuseichochoseizai |
US4297359A (en) * | 1978-07-25 | 1981-10-27 | Acf Chemiefarma Nv | Anti-ulcer compositions containing certain pyridyl oxime ethers |
IL81610A (en) * | 1986-02-27 | 1990-12-23 | Roussel Uclaf | Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them |
US4710508A (en) * | 1986-12-08 | 1987-12-01 | Warner-Lambert Company | O-substituted tetrahydropyridine oxime cholinergic agents |
IT1203971B (it) * | 1987-04-24 | 1989-02-23 | Roussel Maestretti Spa | Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti |
-
1987
- 1987-09-04 US US07/091,893 patent/US4786648A/en not_active Expired - Fee Related
- 1987-11-11 AU AU81102/87A patent/AU607442B2/en not_active Ceased
- 1987-11-30 NZ NZ222756A patent/NZ222756A/xx unknown
- 1987-12-04 FI FI875363A patent/FI85467C/fi not_active IP Right Cessation
- 1987-12-04 DK DK638487A patent/DK638487A/da not_active Application Discontinuation
- 1987-12-07 NO NO875082A patent/NO172045C/no unknown
- 1987-12-07 DE DE8787118083T patent/DE3785312T2/de not_active Expired - Fee Related
- 1987-12-07 PT PT86311A patent/PT86311B/pt not_active IP Right Cessation
- 1987-12-07 PH PH36177A patent/PH23404A/en unknown
- 1987-12-07 EP EP87118083A patent/EP0271798B1/en not_active Expired - Lifetime
- 1987-12-08 KR KR1019870013971A patent/KR960000072B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PT86311A (en) | 1988-01-01 |
NZ222756A (en) | 1989-10-27 |
KR880007466A (ko) | 1988-08-27 |
EP0271798A2 (en) | 1988-06-22 |
EP0271798B1 (en) | 1993-04-07 |
US4786648A (en) | 1988-11-22 |
FI85467C (fi) | 1992-04-27 |
FI875363A (fi) | 1988-06-09 |
NO875082L (no) | 1988-06-09 |
KR960000072B1 (ko) | 1996-01-03 |
DE3785312T2 (de) | 1993-07-22 |
FI875363A0 (fi) | 1987-12-04 |
DK638487D0 (da) | 1987-12-04 |
DK638487A (da) | 1988-06-09 |
NO172045C (no) | 1993-06-02 |
NO875082D0 (no) | 1987-12-07 |
NO172045B (no) | 1993-02-22 |
AU607442B2 (en) | 1991-03-07 |
AU8110287A (en) | 1988-06-09 |
EP0271798A3 (en) | 1989-01-18 |
DE3785312D1 (de) | 1993-05-13 |
PT86311B (pt) | 1990-11-07 |
FI85467B (fi) | 1992-01-15 |
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