DK638487D0 - 0-substituerede tetrahydropyridin-oximer, fremgangsmaade til deres fremstilling og deres anvendelse - Google Patents

0-substituerede tetrahydropyridin-oximer, fremgangsmaade til deres fremstilling og deres anvendelse

Info

Publication number
DK638487D0
DK638487D0 DK638487A DK638487A DK638487D0 DK 638487 D0 DK638487 D0 DK 638487D0 DK 638487 A DK638487 A DK 638487A DK 638487 A DK638487 A DK 638487A DK 638487 D0 DK638487 D0 DK 638487D0
Authority
DK
Denmark
Prior art keywords
oximes
procedures
preparation
substituted tetrahydropyridine
tetrahydropyridine
Prior art date
Application number
DK638487A
Other languages
English (en)
Other versions
DK638487A (da
Inventor
Stephen Clark Bergmeier
David Alexis Downs
Walter Hamilton Moos
David Winslow Moreland
Haile Tecle
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/939,507 external-priority patent/US4710508A/en
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK638487D0 publication Critical patent/DK638487D0/da
Publication of DK638487A publication Critical patent/DK638487A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK638487A 1986-12-08 1987-12-04 0-substituerede tetrahydropyridin-oximer, fremgangsmaade til deres fremstilling og deres anvendelse DK638487A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/939,507 US4710508A (en) 1986-12-08 1986-12-08 O-substituted tetrahydropyridine oxime cholinergic agents
US07/091,893 US4786648A (en) 1986-12-08 1987-09-04 O-substituted tetrahydropyridine oxime cholinergic agents

Publications (2)

Publication Number Publication Date
DK638487D0 true DK638487D0 (da) 1987-12-04
DK638487A DK638487A (da) 1988-06-09

Family

ID=26784455

Family Applications (1)

Application Number Title Priority Date Filing Date
DK638487A DK638487A (da) 1986-12-08 1987-12-04 0-substituerede tetrahydropyridin-oximer, fremgangsmaade til deres fremstilling og deres anvendelse

Country Status (11)

Country Link
US (1) US4786648A (da)
EP (1) EP0271798B1 (da)
KR (1) KR960000072B1 (da)
AU (1) AU607442B2 (da)
DE (1) DE3785312T2 (da)
DK (1) DK638487A (da)
FI (1) FI85467C (da)
NO (1) NO172045C (da)
NZ (1) NZ222756A (da)
PH (1) PH23404A (da)
PT (1) PT86311B (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
US5219873A (en) * 1987-04-24 1993-06-15 Roussel Uclaf Compounds of 1,2,5,6-tetrahydropyridine which are useful as cholinergic agents
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti
IT1222526B (it) * 1987-08-21 1990-09-05 Roussel Maestretti Spa Derivati dell' ossima della 1,2,5,6-tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
US5231107A (en) * 1987-08-21 1993-07-27 Roussel Uclaf Derivatives of the oxime of 1,2,5,6-tetrahydropyridine 3-carboxaldehyde, the process for their preparation, their use as medicaments and the compositions containing them
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
EP0338723B1 (en) * 1988-04-15 1993-08-04 Beecham Group Plc Novel compounds
DK0392803T3 (da) * 1989-04-13 2004-10-18 Beecham Group Plc Hidtil ukendte forbindelser
US5278170A (en) * 1989-04-13 1994-01-11 Beecham Group P.L.C. Azabicylo oxime compounds
IT1240603B (it) * 1990-03-14 1993-12-17 Roussel Maestretti Spa Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale
IT1241138B (it) * 1990-05-15 1993-12-29 Roussel Pharma Derivati dell'ossina della 1,2,5,6- tetraidropiridin-3-carbossaldeide,loro procedimento di preparazione e loro impiego come sostanze medicinali
WO1992003435A1 (en) * 1990-08-24 1992-03-05 Beecham Group Plc Azabicyclic compounds, process and intermediates for their preparation and pharmaceutical compositions containing them
GB9019095D0 (en) * 1990-09-01 1990-10-17 Beecham Group Plc Novel compounds
EP0552213A1 (en) * 1990-10-12 1993-07-28 Beecham Group Plc 1,2,5,6-tetrahydropyridine oxime derivatives
US5175166A (en) * 1991-08-27 1992-12-29 The University Of Toledo Muscarinic agonists
AU3142793A (en) * 1991-12-18 1993-07-19 Warner-Lambert Company Transdermal delivery of (E)-1,2,5,6-tetrahydro-1-methyl-3-pyridine-carboxaldehyde-O- methyloxine HCL and related compounds in the treatment of cognitive disorders and for analgesia
ZA931109B (en) * 1992-03-04 1993-09-22 Akzo Nv Tetrahydropyrimidine derivatives.
US5208343A (en) * 1992-03-24 1993-05-04 Warner-Lambert Company Tetrahydropyridine oxime compounds
ZA937382B (en) * 1992-10-06 1994-04-29 Warner Lambert Co Novel composition for peroral therapy of cognitionimpairment and a process therefor
WO1994007493A1 (en) * 1992-10-06 1994-04-14 Warner-Lambert Company Stabilized compositions containing 1,2,5,6-tetrahydro-1-methyl-3-pyridinecarboxyaldehyde-o-methyl-oxime
WO1994012480A1 (en) * 1992-11-27 1994-06-09 Akzo Nobel N.V. 1,3-diazacycloalkyl oxime derivatives
US5362860A (en) * 1993-02-01 1994-11-08 Warner-Lambert Company Neutral stabilization complex for CI-979 HCl, a cognition activator
US5424301A (en) * 1993-02-01 1995-06-13 Warner-Lambert Company Starch stabilized o-substituted tetrahydropyridine oxime cholinergic agents
US5618818A (en) * 1996-03-20 1997-04-08 The University Of Toledo Muscarinic agonist compounds
EP2147679B1 (en) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions for blood-brain barrier transport
WO2004101422A2 (en) * 2003-05-13 2004-11-25 Oasis Corporation Combined water cooler and refrigerator unit
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
EP2275095A3 (en) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258358A3 (en) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
CA2634999A1 (en) * 2005-12-27 2007-07-05 University Of Toledo Muscarinic agonists and methods of use thereof
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
EP2296471A4 (en) 2008-05-15 2012-03-14 Univ Toledo MUSCARIC ACID AGONISTS AS COGNITIVE ENHANCERS
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
WO2012149524A1 (en) 2011-04-29 2012-11-01 The University Of Toledo Muscarinic agonists as enhancers of working memory and cognitive flexibility

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB889074A (en) * 1959-02-12 1962-02-07 Ciba Ltd New pyridine derivatives and process for their manufacture
FR1258847A (fr) * 1960-02-12 1961-04-21 Ciba Geigy Procédé de préparation de nouveaux dérivés pyridiniques, entre autres de l'oxime de la l-méthyl-3 ou 4-acétyl-1, 2, 5, 6-tétrahydropyridine
JPS511638A (ja) * 1974-06-27 1976-01-08 Fujisawa Pharmaceutical Co Shokubutsuseichochoseizai
US4297359A (en) * 1978-07-25 1981-10-27 Acf Chemiefarma Nv Anti-ulcer compositions containing certain pyridyl oxime ethers
IL81610A (en) * 1986-02-27 1990-12-23 Roussel Uclaf Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them
US4710508A (en) * 1986-12-08 1987-12-01 Warner-Lambert Company O-substituted tetrahydropyridine oxime cholinergic agents
IT1203971B (it) * 1987-04-24 1989-02-23 Roussel Maestretti Spa Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti

Also Published As

Publication number Publication date
NO172045B (no) 1993-02-22
FI85467B (fi) 1992-01-15
KR960000072B1 (ko) 1996-01-03
KR880007466A (ko) 1988-08-27
FI85467C (fi) 1992-04-27
NO172045C (no) 1993-06-02
US4786648A (en) 1988-11-22
FI875363A (fi) 1988-06-09
DK638487A (da) 1988-06-09
EP0271798B1 (en) 1993-04-07
EP0271798A2 (en) 1988-06-22
NO875082D0 (no) 1987-12-07
NZ222756A (en) 1989-10-27
PT86311B (pt) 1990-11-07
DE3785312T2 (de) 1993-07-22
NO875082L (no) 1988-06-09
AU607442B2 (en) 1991-03-07
AU8110287A (en) 1988-06-09
FI875363A0 (fi) 1987-12-04
PH23404A (en) 1989-07-26
EP0271798A3 (en) 1989-01-18
PT86311A (en) 1988-01-01
DE3785312D1 (de) 1993-05-13

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