PH22764A - New bicyclic compounds, method of use and pharmaceutical formulations containing such compounds - Google Patents
New bicyclic compounds, method of use and pharmaceutical formulations containing such compoundsInfo
- Publication number
- PH22764A PH22764A PH28109A PH28109A PH22764A PH 22764 A PH22764 A PH 22764A PH 28109 A PH28109 A PH 28109A PH 28109 A PH28109 A PH 28109A PH 22764 A PH22764 A PH 22764A
- Authority
- PH
- Philippines
- Prior art keywords
- compounds
- pharmaceutical formulations
- formulations containing
- new bicyclic
- bicyclic compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8133942 | 1981-11-10 | ||
GB8133930 | 1981-11-10 | ||
GB8213846 | 1982-05-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
PH22764A true PH22764A (en) | 1988-12-12 |
Family
ID=27261362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH28109A PH22764A (en) | 1981-11-10 | 1982-11-09 | New bicyclic compounds, method of use and pharmaceutical formulations containing such compounds |
Country Status (17)
Country | Link |
---|---|
US (1) | US4603139A (no) |
EP (1) | EP0079083B1 (no) |
KR (1) | KR890000022B1 (no) |
AR (1) | AR241247A1 (no) |
AU (1) | AU9030682A (no) |
DD (1) | DD205904A5 (no) |
DK (1) | DK161325C (no) |
ES (2) | ES517193A0 (no) |
FI (1) | FI79312C (no) |
GB (1) | GB2113675B (no) |
GR (1) | GR76746B (no) |
IE (1) | IE56478B1 (no) |
IL (1) | IL67206A0 (no) |
MC (1) | MC1491A1 (no) |
NO (1) | NO158100C (no) |
PH (1) | PH22764A (no) |
PT (1) | PT75820B (no) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0072926B1 (de) * | 1981-08-19 | 1986-09-24 | MERCK PATENT GmbH | 2-Aryl-imidazopyridine |
US4904785A (en) * | 1982-05-03 | 1990-02-27 | Eli Lilly And Company | 2-phenylimidazo[4,5-c]pyridines |
US4758574A (en) * | 1982-05-03 | 1988-07-19 | Eli Lilly And Company | 2-phenylimidazio (4,5-c) pyridines |
ZA832938B (en) * | 1982-05-03 | 1984-12-24 | Lilly Co Eli | 2-phenylimidazo(4,5-c)pyridines |
DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
DE3324115A1 (de) * | 1983-07-05 | 1985-01-17 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
US4515796A (en) * | 1983-09-08 | 1985-05-07 | Eli Lilly And Company | Certain naphthalenyl imidazo compounds and their pharmaceutical use |
US4533734A (en) * | 1983-11-10 | 1985-08-06 | Eli Lilly And Company | Inotropic agents |
DE3346602A1 (de) * | 1983-12-23 | 1985-07-11 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazo(4,5-c)pyridin-one, deren herstellung und diese verbindungen enthaltende arzneimittel |
DE3347290A1 (de) * | 1983-12-28 | 1985-07-11 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue 2-phenyl-imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel |
ZA851236B (en) * | 1984-02-24 | 1986-09-24 | Lilly Co Eli | 2-arylimidazo 4,5-cpyridines |
US4578387A (en) * | 1984-03-05 | 1986-03-25 | Eli Lilly And Company | Inotropic agents |
DE3445299A1 (de) * | 1984-12-12 | 1986-06-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
IL78241A0 (en) * | 1985-03-29 | 1986-07-31 | Lilly Co Eli | Synthesis of inotropic imidazo(4,5-c)pyridine |
DE3522230A1 (de) * | 1985-06-21 | 1987-01-02 | Thomae Gmbh Dr K | Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
US4740599A (en) * | 1986-10-03 | 1988-04-26 | Eli Lilly And Company | Synthesis of alkylsulfinyl substituted 2-phenylimidazo(4,5-c)pyridines |
ZA889365B (en) * | 1987-12-22 | 1990-08-29 | Lilly Co Eli | Hydrates of andinotropic agent |
GB8822170D0 (en) * | 1988-09-21 | 1988-10-26 | Pfizer Ltd | Therapeutic agents |
DE69104481T2 (de) * | 1990-05-09 | 1995-02-09 | Pfizer | Imidazo[4,5-c]pyridine als paf antagonisten. |
DE4324580A1 (de) * | 1993-07-22 | 1995-01-26 | Thomae Gmbh Dr K | Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
DK0912568T3 (da) * | 1996-05-15 | 2003-03-10 | Altana Pharma Ag | Imidazopyridiner |
ATE256683T1 (de) * | 1996-11-11 | 2004-01-15 | Altana Pharma Ag | Neue imidazo- und oxazolopyridine als phosphodiesterase inhibitoren. |
WO2001096336A2 (en) * | 2000-06-14 | 2001-12-20 | Warner-Lambert Company | 6,5-fused bicyclic heterocycles |
CA2516522A1 (en) * | 2003-02-25 | 2004-09-10 | Altana Pharma Ag | Imidazo[4,5-b]quinoline-derivatives and their use as no-synthase inhibitors |
KR20060087386A (ko) * | 2005-01-28 | 2006-08-02 | 주식회사 대웅제약 | 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물 |
WO2007034277A1 (en) * | 2005-09-19 | 2007-03-29 | Pfizer Products Inc. | Aryl substituted imidazo [4,5-c] pyridine compounds as c3a receptor antagonists |
PE20131197A1 (es) | 2008-10-31 | 2013-11-06 | Genentech Inc | Compuestos de pirazolopirimidina como inhibidores de jak y composiciones farmaceuticas que los contienen |
UA110324C2 (en) | 2009-07-02 | 2015-12-25 | Genentech Inc | Jak inhibitory compounds based on pyrazolo pyrimidine |
CA2770116C (en) * | 2009-08-10 | 2018-03-13 | Epitherix, Llc | Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof |
PT3001903T (pt) | 2009-12-21 | 2017-12-18 | Samumed Llc | 1h-pirazolo[3,4-b]piridinas e usos terapêuticos destas |
KR20130001272A (ko) * | 2010-03-17 | 2013-01-03 | 에프. 호프만-라 로슈 아게 | 이미다조피리딘 및 푸린 화합물, 조성물 및 사용 방법 |
AR082974A1 (es) | 2010-09-15 | 2013-01-23 | Hoffmann La Roche | Derivados de azabenzotiazol, composiciones farmaceuticas que los contienen, metodo para prepararlos y uso de los mismos para tratar enfermedades inflamatorias |
BR112013011520A2 (pt) | 2010-11-19 | 2019-09-24 | Hoffmann La Roche | pirazolo piridinas e pirazolo piridinas e seu uso como inibidores de tyk2 |
IN2014CN02646A (no) | 2011-09-14 | 2015-08-07 | Samumed Llc | |
PH12017500997A1 (en) | 2012-04-04 | 2018-02-19 | Samumed Llc | Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof |
PT2770994T (pt) | 2012-05-04 | 2019-11-04 | Samumed Llc | 1h-pirazolo[3,4-b]piridinas e utilizações terapêuticas destas |
EP2943198B1 (en) | 2013-01-08 | 2019-07-17 | Samumed, LLC | 3-(benzoimidazol-2-yl)-indazole inhibitors of the wnt signaling pathway and therapeutic uses thereof |
EP2818472A1 (en) * | 2013-06-27 | 2014-12-31 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Imidazo[4,5-c]pyridine and pyrrolo[3,2-c]pyridine compounds as G-protein-coupled receptor kinase 5 (GRK5) modulators |
US11229208B2 (en) | 2013-07-02 | 2022-01-25 | Syngenta Participations Ag | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents |
US10939682B2 (en) * | 2013-07-02 | 2021-03-09 | Syngenta Participations Ag | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents |
CN105431433B (zh) * | 2013-07-02 | 2018-04-06 | 先正达参股股份有限公司 | 有杀有害生物活性的具有含硫取代基的二环或三环杂环 |
US10364243B2 (en) | 2014-02-17 | 2019-07-30 | Bayer Cropscience Aktiengesellschaft | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides |
SI3145929T1 (sl) | 2014-05-23 | 2021-10-29 | Hoffmann La Roche | 5-kloro-2-difluorometoksifenil pirazolopirimidinove spojine, ki so zaviralci janusove kinaze |
JP6695326B2 (ja) | 2014-08-21 | 2020-05-20 | シンジェンタ パーティシペーションズ アーゲー | 硫黄含有置換基を有する殺有害生物的に活性な複素環式誘導体 |
WO2016040180A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040190A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof |
WO2016040188A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040193A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-b]pyridine and therapeutic uses thereof |
WO2016040181A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016040182A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 2-(1h-indazol-3-yl)-1h-imidazo[4,5-c]pyridine and therapeutic uses thereof |
WO2016040185A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 2-(1h-indazol-3-yl)-3h-imidazo[4,5-b]pyridine and therapeutic uses thereof |
WO2016040184A1 (en) | 2014-09-08 | 2016-03-17 | Samumed, Llc | 3-(3h-imidazo[4,5-b]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridine and therapeutic uses thereof |
WO2016058928A1 (en) * | 2014-10-14 | 2016-04-21 | Syngenta Participations Ag | Pesticidally active heterocyclic derivatives with sulphur containing substituents |
DK3233851T3 (da) * | 2014-12-17 | 2020-08-31 | Syngenta Participations Ag | Pesticidaktive heterocykliske derivater med svovlindeholdende substituenter |
ES2729984T3 (es) * | 2014-12-31 | 2019-11-07 | Syngenta Participations Ag | Derivados policíclicos activos como plaguicida que contienen sustituyentes de azufre |
UY36547A (es) * | 2015-02-05 | 2016-06-01 | Bayer Cropscience Ag | Derivados heterocíclicos condensados bicíclicos sustituidos por 2-(het)arilo como pesticidas |
WO2017023984A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-pyrazolo[3,4-c]pyridines and therapeutic uses thereof |
WO2017023989A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-benzo[d]imidazol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
WO2017023986A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc | 3-(1h-indol-2-yl)-1h-indazoles and therapeutic uses thereof |
US10226448B2 (en) | 2015-08-03 | 2019-03-12 | Samumed, Llc | 3-(1H-pyrrolo[3,2-C]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridines and therapeutic uses thereof |
US10166218B2 (en) | 2015-08-03 | 2019-01-01 | Samumed, Llc | 3-(1H-indol-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof |
WO2017023988A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(3h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
US10285982B2 (en) | 2015-08-03 | 2019-05-14 | Samumed, Llc | 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof |
US10231956B2 (en) | 2015-08-03 | 2019-03-19 | Samumed, Llc | 3-(1H-pyrrolo[3,2-C]pyridin-2-YL)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
WO2017024021A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc | 3-(1h-pyrrolo[2,3-b]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof |
US10285983B2 (en) | 2015-08-03 | 2019-05-14 | Samumed, Llc | 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[3,4-B] pyridines and therapeutic uses thereof |
US10519169B2 (en) | 2015-08-03 | 2019-12-31 | Samumed, Llc | 3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1 H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
WO2017023993A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-indol-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
WO2017024010A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-pyrrolo[3,2-c]pyridin-2-yl)-1h-indazoles and therapeutic uses thereof |
US10329309B2 (en) | 2015-08-03 | 2019-06-25 | Samumed, Llc | 3-(3H-imidazo[4,5-B]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
US10206909B2 (en) | 2015-08-03 | 2019-02-19 | Samumed, Llc | 3-(1H-pyrrolo[2,3-B]pyridin-2-yl)-1H-pyrazolo[4,3-B]pyridines and therapeutic uses thereof |
US10383861B2 (en) | 2015-08-03 | 2019-08-20 | Sammumed, LLC | 3-(1H-pyrrolo[2,3-C]pyridin-2-yl)-1H-pyrazolo[3,4-C]pyridines and therapeutic uses thereof |
WO2017023972A1 (en) | 2015-08-03 | 2017-02-09 | Samumed, Llc. | 3-(1h-imidazo[4,5-c]pyridin-2-yl)-1h-pyrazolo[4,3-b]pyridines and therapeutic uses thereof |
EP3370721A4 (en) | 2015-11-06 | 2019-05-22 | Samumed, LLC | TREATMENT OF OSTEOARTHRITIS |
JP7010851B2 (ja) | 2016-06-01 | 2022-02-10 | バイオスプライス セラピューティクス インコーポレイテッド | N-(5-(3-(7-(3-フルオロフェニル)-3H-イミダゾ[4,5-c]ピリジン-2-イル)-1H-インダゾール-5-イル)ピリジン-3-イル)-3-メチルブタンアミドを調製するための方法 |
BR112019008061A2 (pt) | 2016-10-21 | 2019-09-17 | Samumed Llc | métodos de uso de indazol-3-carboxamidas e seu uso como inibidores da via de sinalização de wnt/b-catenina |
US10758523B2 (en) | 2016-11-07 | 2020-09-01 | Samumed, Llc | Single-dose, ready-to-use injectable formulations |
SG11201909735YA (en) | 2017-05-22 | 2019-11-28 | Hoffmann La Roche | Therapeutic compounds and compositions, and methods of use thereof |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA820316A (en) * | 1969-08-12 | Fisons Pest Control Limited | Substituted heterocyclic compounds | |
US3985891A (en) * | 1973-02-03 | 1976-10-12 | Boehringer Ingelheim Gmbh | 2-Phenyl-imidazo (4,5-b)pyridines and salts thereof |
FI58126C (fi) * | 1973-02-03 | 1980-12-10 | Thomae Gmbh Dr K | Foerfarande foer framstaellning av kardiotona och blodtryckssaenkande 2-fenyl-1h-imidatso(4,5-b)pyridiner |
US3891660A (en) * | 1974-02-07 | 1975-06-24 | Squibb & Sons Inc | Derivatives of 1H-imidazo{8 4,5-c{9 pyridine-7-carboxylic acids and esters |
SU566842A1 (ru) * | 1976-01-06 | 1977-07-30 | Донецкое Отделение Физико-Органической Химии Института Физической Химии Им.Л.В.Писаржевского Ан Украинской Сср | Способ получени замещенных имидазопиридинов |
US4281005A (en) * | 1979-03-05 | 1981-07-28 | Merck & Co., Inc. | Novel 2-pyridylimidazole compounds |
DE2927987A1 (de) * | 1979-07-11 | 1981-02-05 | Thomae Gmbh Dr K | Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel |
DE3037464A1 (de) * | 1980-10-03 | 1982-05-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | 6-hydroxy-2-phenyl-imidazo 4,5-b zu pyridine, ihre herstellung und diese sie enthaltende arzneimittel |
EP0072926B1 (de) * | 1981-08-19 | 1986-09-24 | MERCK PATENT GmbH | 2-Aryl-imidazopyridine |
ZA832938B (en) * | 1982-05-03 | 1984-12-24 | Lilly Co Eli | 2-phenylimidazo(4,5-c)pyridines |
DE3224512A1 (de) * | 1982-07-01 | 1984-01-05 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
-
1982
- 1982-11-08 ES ES517193A patent/ES517193A0/es active Granted
- 1982-11-09 IE IE2667/82A patent/IE56478B1/en not_active IP Right Cessation
- 1982-11-09 DK DK499582A patent/DK161325C/da not_active IP Right Cessation
- 1982-11-09 MC MC821611A patent/MC1491A1/xx unknown
- 1982-11-09 FI FI823846A patent/FI79312C/fi not_active IP Right Cessation
- 1982-11-09 EP EP82110328A patent/EP0079083B1/en not_active Expired - Lifetime
- 1982-11-09 PH PH28109A patent/PH22764A/en unknown
- 1982-11-09 DD DD82244689A patent/DD205904A5/de not_active IP Right Cessation
- 1982-11-09 AR AR82291240A patent/AR241247A1/es active
- 1982-11-09 NO NO823732A patent/NO158100C/no unknown
- 1982-11-09 AU AU90306/82A patent/AU9030682A/en not_active Abandoned
- 1982-11-09 GB GB08231984A patent/GB2113675B/en not_active Expired
- 1982-11-09 PT PT75820A patent/PT75820B/pt unknown
- 1982-11-09 GR GR69767A patent/GR76746B/el unknown
- 1982-11-09 KR KR8205055A patent/KR890000022B1/ko active
- 1982-11-09 IL IL67206A patent/IL67206A0/xx unknown
-
1983
- 1983-06-08 ES ES523083A patent/ES8503351A1/es not_active Expired
-
1985
- 1985-01-11 US US06/690,815 patent/US4603139A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES8401486A1 (es) | 1983-12-01 |
NO823732L (no) | 1983-05-11 |
GR76746B (no) | 1984-08-30 |
AR241247A1 (es) | 1992-03-31 |
US4603139A (en) | 1986-07-29 |
ES523083A0 (es) | 1985-02-16 |
FI823846A0 (fi) | 1982-11-09 |
DK161325B (da) | 1991-06-24 |
FI79312B (fi) | 1989-08-31 |
ES517193A0 (es) | 1983-12-01 |
KR890000022B1 (ko) | 1989-03-06 |
IL67206A0 (en) | 1983-03-31 |
PT75820A (en) | 1982-12-01 |
FI823846L (fi) | 1983-05-11 |
IE56478B1 (en) | 1991-08-14 |
DK161325C (da) | 1991-12-02 |
MC1491A1 (fr) | 1983-09-12 |
DK499582A (da) | 1983-05-11 |
IE822667L (en) | 1983-05-10 |
AU9030682A (en) | 1983-05-19 |
KR840002398A (ko) | 1984-07-02 |
DD205904A5 (de) | 1984-01-11 |
GB2113675A (en) | 1983-08-10 |
NO158100C (no) | 1988-07-13 |
EP0079083B1 (en) | 1991-02-27 |
PT75820B (en) | 1986-06-11 |
GB2113675B (en) | 1985-10-30 |
EP0079083A1 (en) | 1983-05-18 |
ES8503351A1 (es) | 1985-02-16 |
NO158100B (no) | 1988-04-05 |
FI79312C (fi) | 1989-12-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PH22764A (en) | New bicyclic compounds, method of use and pharmaceutical formulations containing such compounds | |
PH20243A (en) | Cephalosporin derivatives, pharmaceutical formulation containing same and method of use thereof | |
PH16326A (en) | New chemical compounds,pharmaceutical compositions containing the same and method of use | |
IL67572A0 (en) | New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these compounds and their use,and new bicyclic aminoacids as intermediates and processes for their preparation | |
PT81015A (en) | Process for the preparation of bicyclic compounds and of pharmaceutical compositions containing | |
PH18979A (en) | Banzazepine derivatives,their pharmaceutical compositions and method of use | |
PH23447A (en) | B-actam compounds,pharmaceutical compositions containing the same and method of use thereof | |
PH20784A (en) | 1,4-naphthoquinones,pharmaceutical composition containing same and method of use thereof | |
PH20921A (en) | Polyprenyl compound drugs containing the same and method of use | |
PH23486A (en) | Indole analogs of mevalonolactone,pharmaceutical compositions containing the same and method of use thereof | |
PH20358A (en) | Mitomycin analogs pharmaceutical composition containing same and method of use thereof | |
PT75042A (en) | Process for the preparation of apovincaminates and pharmaceutical compositions containing them | |
PH18784A (en) | Fused 4h-1,4-benzothiazines,method of use and pharmaceutical composition containing them | |
ZA812034B (en) | Phrimidyl-quinazolines,process for their preparation pharmaceutical formulations containing these compounds,and their use | |
DE3277171D1 (en) | Pharmaceutical composition and the use of sn- or cr-protoporphyrin for the manufacture thereof | |
ZA839437B (en) | Substituted azabicycloalkanes,the use thereof,pharmaceutical compositions containing them,and processes for the preparation of these compounds | |
PT75265A (en) | Process for the preparation of diazabicyclicononanes substituted and pharmaceutical composition containing them | |
PH19347A (en) | Triazole derivatives,pharmaceutical composition containing same and method of use thereof | |
ZA828213B (en) | New bicyclic compounds,processes for their preparation and pharmaceutical formulations containing such compounds | |
ZW20982A1 (en) | Aminooxazolyl compounds processes for their manufacture pharmaceutical preparations containing these compounds and the use of the latter | |
PH21606A (en) | Penem compounds, pharmaceutical composition containing said compounds and method of use thereof | |
EP0058079A3 (en) | Imidazole derivative, method of preparation thereof, and pharmaceutical composition containing same | |
PT74400B (en) | Process for the preparation of 17,18-dehydro-apovincaminol-3', 4',5'-trimethoxy-benzoate and of pharmaceutical compositions containing them | |
PH16860A (en) | Novel indane derivatives,pharmaceutical compositions containing said derivatives and method of use thereof | |
PT83231A (en) | Process for the preparation of gem-dihalo-1,8-diamino-4-aza-octanes and of pharmaceutical compositions containing the same |