PH18683A - Novel 4-aroylimidazol-2-ones and their use - Google Patents

Novel 4-aroylimidazol-2-ones and their use

Info

Publication number
PH18683A
PH18683A PH24143A PH24143A PH18683A PH 18683 A PH18683 A PH 18683A PH 24143 A PH24143 A PH 24143A PH 24143 A PH24143 A PH 24143A PH 18683 A PH18683 A PH 18683A
Authority
PH
Philippines
Prior art keywords
aroylimidazol
ones
novel
Prior art date
Application number
PH24143A
Other languages
English (en)
Inventor
Richard A Schnettler
Richard C Dage
J Martin Grisar
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH18683(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of PH18683A publication Critical patent/PH18683A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH24143A 1979-06-18 1980-06-16 Novel 4-aroylimidazol-2-ones and their use PH18683A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4980879A 1979-06-18 1979-06-18
US11920780A 1980-02-07 1980-02-07

Publications (1)

Publication Number Publication Date
PH18683A true PH18683A (en) 1985-08-29

Family

ID=26727558

Family Applications (1)

Application Number Title Priority Date Filing Date
PH24143A PH18683A (en) 1979-06-18 1980-06-16 Novel 4-aroylimidazol-2-ones and their use

Country Status (20)

Country Link
AT (1) AT375349B (enExample)
AU (1) AU532783B2 (enExample)
CA (1) CA1132554A (enExample)
CH (1) CH646155A5 (enExample)
DE (1) DE3021792A1 (enExample)
DK (1) DK160269C (enExample)
ES (1) ES492255A0 (enExample)
FR (1) FR2459233A1 (enExample)
GB (1) GB2055364B (enExample)
HK (1) HK61486A (enExample)
HU (1) HU186736B (enExample)
IE (1) IE50646B1 (enExample)
IL (1) IL60243A (enExample)
IT (1) IT1143922B (enExample)
MY (1) MY8600709A (enExample)
NL (2) NL193752C (enExample)
NO (1) NO152841C (enExample)
NZ (1) NZ193935A (enExample)
PH (1) PH18683A (enExample)
SE (2) SE447107B (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4381393A (en) * 1981-05-04 1983-04-26 Merrell Dow Pharmaceuticals Inc. 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4371737A (en) * 1981-05-04 1983-02-01 Merrell Dow Pharmaceuticals Inc. 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
ZA822990B (en) * 1981-05-04 1983-03-30 Merrell Dow Pharma 4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones
US4526981A (en) * 1981-05-04 1985-07-02 Merrell Dow Pharmaceuticals Inc. [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
US4329471A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4329470A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4367236A (en) 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2007530566A (ja) * 2004-03-22 2007-11-01 ミオゲン インコーポレイティッド （ｒ）−エノキシモンスルホキシドおよびｐｄｅ−ｉｉｉ媒介疾患の治療におけるその使用
EP1737448A1 (en) * 2004-03-22 2007-01-03 Myogen, Inc. (s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
US8067433B2 (en) 2005-11-09 2011-11-29 Zalicus Inc. Methods, compositions, and kits for the treatment of ophthalmic disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2627848T3 (es) 2008-06-04 2017-07-31 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
MX357121B (es) 2011-03-01 2018-06-27 Synergy Pharmaceuticals Inc Star Proceso de preparacion de agonistas c de guanilato ciclasa.
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
EP2958577A2 (en) 2013-02-25 2015-12-30 Synergy Pharmaceuticals Inc. Guanylate cyclase receptor agonists for use in colonic cleansing
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
PL3004138T3 (pl) 2013-06-05 2024-07-29 Bausch Health Ireland Limited Ultra-oczyszczeni agoniści peptydowi cyklazy guanylanowej C, sposób ich uzyskiwania i ich zastosowanie
CA2920856C (en) 2013-08-09 2026-03-03 Ardelyx, Inc. Ph modulating compounds for inhibiting gastrointestinal phosphate uptake
JP2022533251A (ja) 2019-05-21 2022-07-21 アルデリックス， インコーポレイテッド 患者において血清リン酸塩を低下させるための組み合わせ
CN114539157B (zh) * 2022-03-03 2023-12-22 曲靖师范学院 一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them

Also Published As

Publication number Publication date
NO152841C (no) 1985-11-27
IL60243A0 (en) 1980-09-16
GB2055364A (en) 1981-03-04
NL193752B (nl) 2000-05-01
IE50646B1 (en) 1986-06-11
SE8004253L (sv) 1980-12-19
NL300015I1 (nl) 2000-11-01
CA1132554A (en) 1982-09-28
SE447107B (sv) 1986-10-27
MY8600709A (en) 1986-12-31
SE464559B (sv) 1991-05-13
IE801162L (en) 1980-12-18
NO801796L (no) 1980-12-19
ATA314280A (de) 1983-12-15
DK259080A (da) 1980-12-19
CH646155A5 (de) 1984-11-15
NL193752C (nl) 2000-09-04
DE3021792C2 (enExample) 1989-08-10
DK160269B (da) 1991-02-18
SE8501452D0 (sv) 1985-03-25
IT8048997A0 (it) 1980-06-17
NO152841B (no) 1985-08-19
HK61486A (en) 1986-08-29
AT375349B (de) 1984-07-25
ES8105299A1 (es) 1981-06-01
AU532783B2 (en) 1983-10-13
SE8501452L (sv) 1985-03-25
ES492255A0 (es) 1981-06-01
GB2055364B (en) 1983-06-08
NZ193935A (en) 1985-05-31
NL8003498A (nl) 1980-12-22
IT1143922B (it) 1986-10-29
HU186736B (en) 1985-09-30
NL300015I2 (nl) 2000-10-02
DK160269C (da) 1991-07-22
AU5911880A (en) 1981-01-08
FR2459233A1 (fr) 1981-01-09
IL60243A (en) 1987-01-30
DE3021792A1 (de) 1981-01-22
FR2459233B1 (enExample) 1983-09-23

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