PH12015501204B1 - Tobacco specific nitrosamine reduction in plants - Google Patents
Tobacco specific nitrosamine reduction in plantsInfo
- Publication number
- PH12015501204B1 PH12015501204B1 PH1/2015/501204A PH12015501204A PH12015501204B1 PH 12015501204 B1 PH12015501204 B1 PH 12015501204B1 PH 12015501204 A PH12015501204 A PH 12015501204A PH 12015501204 B1 PH12015501204 B1 PH 12015501204B1
- Authority
- PH
- Philippines
- Prior art keywords
- seq
- mutant
- naturally occurring
- plants
- polynucleotide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
- A24B15/241—Extraction of specific substances
- A24B15/245—Nitrosamines
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B3/00—Preparing tobacco in the factory
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Virology (AREA)
- Botany (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physiology (AREA)
- Developmental Biology & Embryology (AREA)
- Environmental Sciences (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Manufacture Of Tobacco Products (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12198966 | 2012-12-21 | ||
| PCT/EP2013/077532 WO2014096283A2 (en) | 2012-12-21 | 2013-12-19 | Tobacco specific nitrosamine reduction in plants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PH12015501204A1 PH12015501204A1 (en) | 2015-08-17 |
| PH12015501204B1 true PH12015501204B1 (en) | 2022-07-15 |
Family
ID=47559184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH1/2015/501204A PH12015501204B1 (en) | 2012-12-21 | 2013-12-19 | Tobacco specific nitrosamine reduction in plants |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US10563215B2 (enExample) |
| EP (1) | EP2935588B1 (enExample) |
| JP (1) | JP6693747B2 (enExample) |
| KR (1) | KR102253223B1 (enExample) |
| CN (1) | CN105247053B (enExample) |
| AP (1) | AP2015008563A0 (enExample) |
| CA (1) | CA2894955C (enExample) |
| MX (2) | MX2015008084A (enExample) |
| PH (1) | PH12015501204B1 (enExample) |
| RU (1) | RU2735254C2 (enExample) |
| WO (1) | WO2014096283A2 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9980509B2 (en) | 2013-04-05 | 2018-05-29 | R.J. Reynolds Tobacco Company | Modification of bacterial profile of tobacco |
| EP3160988A2 (en) * | 2014-06-25 | 2017-05-03 | Philip Morris Products S.A. | Modulation of biomass in plants by ectopic expression of a chloride channel |
| GB201501941D0 (en) * | 2015-02-05 | 2015-03-25 | British American Tobacco Co | Method |
| HK1250883A1 (zh) * | 2015-05-05 | 2019-01-18 | North Carolina State University | 减少烟草中的烟草特异性亚硝胺nnk的方法和组合物 |
| WO2017156535A1 (en) * | 2016-03-11 | 2017-09-14 | Altria Client Services Llc | Compositions and methods for producing tobacco plants and products having reduced or eliminated suckers |
| JP2020529206A (ja) | 2017-07-31 | 2020-10-08 | アール・ジエイ・レイノルズ・タバコ・カンパニー | 植物におけるウイルスベースの遺伝子編集のための方法及び組成物 |
| WO2019185699A1 (en) | 2018-03-28 | 2019-10-03 | Philip Morris Products S.A. | Modulating reducing sugar content in a plant |
| KR102995073B1 (ko) | 2018-03-28 | 2026-07-24 | 필립모리스 프로덕츠 에스.에이. | 식물 내 아미노산 함량 조절 |
| GB201812603D0 (en) | 2018-08-02 | 2018-09-19 | British American Tobacco Investments Ltd | Method |
| EP3902390A1 (en) * | 2018-12-30 | 2021-11-03 | Philip Morris Products S.A. | Modulation of nitrate levels in plants via mutation of nitrate reductase |
| WO2020247821A2 (en) * | 2019-06-05 | 2020-12-10 | R.J. Reynolds Tobacco Company | bZIP TRANSCRIPTION FACTORS REGULATE CONVERSION OF NICOTINE TO NORNICOTINE AND REDUCE LEVELS OF TOBACCO SPECIFIC (TSNA) PRECURSORS |
| CN110499388B (zh) * | 2019-09-29 | 2023-03-24 | 云南省烟草农业科学研究院 | 鉴别烟草抗斑萎病位点rtsw等位基因类型的共显性标记引物组、鉴别方法及其应用 |
| WO2021063863A1 (en) | 2019-10-01 | 2021-04-08 | Philip Morris Products S.A. | Modulating sugar and amino acid content in a plant (sultr3) |
| KR20220070305A (ko) | 2019-10-01 | 2022-05-30 | 필립모리스 프로덕츠 에스.에이. | 식물 내 환원당 (inv) 함량 조절 |
| CN111690661A (zh) * | 2020-06-01 | 2020-09-22 | 云南省烟草农业科学研究院 | 一种烟草NtbHLH13基因突变体及分子鉴定方法和应用 |
| US20240368615A1 (en) | 2021-09-10 | 2024-11-07 | Philip Morris Products S.A. | Modulating alkaloid profiles in nicotiana tabacum |
| WO2023117661A1 (en) | 2021-12-20 | 2023-06-29 | Philip Morris Products S.A. | Increasing anatabine in tobacco leaf by regulating methyl putrescine oxidase |
| US20250084427A1 (en) | 2021-12-21 | 2025-03-13 | Philip Morris Products S.A. | Modulation of nicotine production by alteration of nicotinamidase expression or function in plants |
| CN118475234A (zh) * | 2021-12-27 | 2024-08-09 | 日本烟草产业株式会社 | 烟草植物 |
| KR20250078994A (ko) | 2022-10-13 | 2025-06-04 | 필립모리스 프로덕츠 에스.에이. | Ntp2 조절에 의한 잎 바이오매스 및 질소 사용 효율 증가 |
| KR20250139371A (ko) | 2023-02-02 | 2025-09-23 | 필립모리스 프로덕츠 에스.에이. | 당 수송체의 조절 |
| WO2024160860A1 (en) | 2023-02-02 | 2024-08-08 | Philip Morris Products S.A. | Modulation of genes coding for lysine ketoglutarate reductase |
| WO2025003105A1 (en) | 2023-06-29 | 2025-01-02 | Philip Morris Products S.A. | Modulation of genes coding for glutamate dehydrogenase |
| CN117025626B (zh) * | 2023-06-29 | 2025-02-14 | 中国烟草总公司郑州烟草研究院 | 烟草硝酸盐转运蛋白NtNPF7.4及其编码基因、基因编辑载体和应用 |
| CN117025627B (zh) * | 2023-06-29 | 2024-11-01 | 中国烟草总公司郑州烟草研究院 | 烟草氯离子通道蛋白NtCLC13及其编码基因和应用 |
| CN120944912B (zh) * | 2025-09-17 | 2026-05-08 | 河南省农业科学院烟草研究所 | NtGCN1基因及其在调控烟叶氯离子含量中的应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5810020A (en) | 1993-09-07 | 1998-09-22 | Osmotek, Inc. | Process for removing nitrogen-containing anions and tobacco-specific nitrosamines from tobacco products |
| US6202649B1 (en) | 1996-12-02 | 2001-03-20 | Regent Court Technologies | Method of treating tobacco to reduce nitrosamine content, and products produced thereby |
| US6586661B1 (en) * | 1997-06-12 | 2003-07-01 | North Carolina State University | Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid |
| EE9900590A (et) | 1997-06-20 | 2000-08-15 | Regent Court Technologies | Nitrosamiinide sisaldust vähendav tubaka töötlemise meetod ja seejuures saadavad tooted |
| US7700834B2 (en) * | 2001-11-13 | 2010-04-20 | U.S. Smokless Tobacco Company | Nicotiana nucleic acid molecules and uses thereof |
| RU2191529C1 (ru) | 2001-12-21 | 2002-10-27 | Романенко Александр Павлович | Устройство для курения |
| DK1623634T3 (da) * | 2003-05-06 | 2013-07-15 | Japan Tobacco Inc | Fremgangsmåde til fremstilling af regenereret tobaksmateriale |
| JP4160868B2 (ja) * | 2003-07-10 | 2008-10-08 | 日本たばこ産業株式会社 | 葉タバコ中のニトロソアミン含量の低減方法 |
| OA13241A (en) * | 2003-08-19 | 2007-01-31 | 22Nd Century Ltd Llc | Reduced-exposure tobacco products. |
| ATE530656T1 (de) | 2005-02-23 | 2011-11-15 | Univ North Carolina State | Veränderung des alkaloidgehaltes in tabak durch modifikation spezifischer cytochrome p450 gene. |
| AU2007329776B2 (en) | 2006-10-13 | 2013-05-16 | North Carolina State University | Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes |
| RU2324737C1 (ru) * | 2006-10-18 | 2008-05-20 | Институт цитологии и генетики Сибирского отделения Российской академии наук (СО РАН) | Способ получения трансгенных растений табака с повышенным содержанием пролина |
| ES2716864T3 (es) | 2007-06-06 | 2019-06-17 | Monsanto Technology Llc | Genes y usos para la mejora de plantas |
| CN101939431B (zh) | 2007-11-12 | 2015-01-28 | 北卡罗来纳州立大学 | 通过修饰特定细胞色素p450基因改变烟草生物碱含量 |
| AP3226A (en) | 2007-12-13 | 2015-04-30 | Philip Morris Products Sa | Transgenic plants modifier for reducede cadmium transport, derivative products, and related methods |
| WO2009091518A2 (en) * | 2008-01-15 | 2009-07-23 | Monsanto Technology, Llc | Isolated novel nucleic acid and protein molecules from corn and methods of using those molecules to generate transgenic plant with enhanced agronomic traits |
| KR20120126061A (ko) * | 2009-10-22 | 2012-11-20 | 재단법인 작물유전체기능연구사업단 | 향상된 수확량 관련 형질을 갖는 식물 및 이의 제조 방법 |
| MX337123B (es) | 2010-01-15 | 2016-02-12 | Univ North Carolina State | Composiciones y metodos para minimizar la sintesis de nornicotina en el tabaco. |
| ES2698154T3 (es) | 2010-09-03 | 2019-01-31 | Philip Morris Products Sa | Reducción de metales pesados en plantas |
-
2013
- 2013-12-19 CA CA2894955A patent/CA2894955C/en active Active
- 2013-12-19 CN CN201380073174.4A patent/CN105247053B/zh active Active
- 2013-12-19 MX MX2015008084A patent/MX2015008084A/es unknown
- 2013-12-19 US US14/653,924 patent/US10563215B2/en active Active
- 2013-12-19 EP EP13817681.3A patent/EP2935588B1/en active Active
- 2013-12-19 PH PH1/2015/501204A patent/PH12015501204B1/en unknown
- 2013-12-19 WO PCT/EP2013/077532 patent/WO2014096283A2/en not_active Ceased
- 2013-12-19 AP AP2015008563A patent/AP2015008563A0/xx unknown
- 2013-12-19 JP JP2015548608A patent/JP6693747B2/ja active Active
- 2013-12-19 KR KR1020157018188A patent/KR102253223B1/ko active Active
- 2013-12-19 RU RU2015126909A patent/RU2735254C2/ru active
-
2015
- 2015-06-19 MX MX2019001598A patent/MX2019001598A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PH12015501204A1 (en) | 2015-08-17 |
| KR102253223B1 (ko) | 2021-05-21 |
| AP2015008563A0 (en) | 2015-06-30 |
| CN105247053A (zh) | 2016-01-13 |
| JP6693747B2 (ja) | 2020-05-13 |
| WO2014096283A2 (en) | 2014-06-26 |
| EP2935588B1 (en) | 2026-03-25 |
| MX2019001598A (es) | 2019-07-01 |
| US20150315603A1 (en) | 2015-11-05 |
| RU2015126909A (ru) | 2017-01-27 |
| MX2015008084A (es) | 2016-03-31 |
| CA2894955A1 (en) | 2014-06-26 |
| EP2935588C0 (en) | 2026-03-25 |
| RU2735254C2 (ru) | 2020-10-29 |
| US10563215B2 (en) | 2020-02-18 |
| JP2016508032A (ja) | 2016-03-17 |
| CA2894955C (en) | 2023-10-31 |
| KR20150096451A (ko) | 2015-08-24 |
| CN105247053B (zh) | 2020-07-31 |
| EP2935588A2 (en) | 2015-10-28 |
| WO2014096283A3 (en) | 2014-08-14 |
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