AP2015008563A0 - Tobacco specific nitrosamine reduction in plants - Google Patents

Tobacco specific nitrosamine reduction in plants

Info

Publication number
AP2015008563A0
AP2015008563A0 AP2015008563A AP2015008563A AP2015008563A0 AP 2015008563 A0 AP2015008563 A0 AP 2015008563A0 AP 2015008563 A AP2015008563 A AP 2015008563A AP 2015008563 A AP2015008563 A AP 2015008563A AP 2015008563 A0 AP2015008563 A0 AP 2015008563A0
Authority
AP
ARIPO
Prior art keywords
plants
specific nitrosamine
tobacco specific
reduction
nitrosamine reduction
Prior art date
Application number
AP2015008563A
Other languages
English (en)
Inventor
Prisca Campanoni
Lucien Bovet
Original Assignee
Philip Morris Products Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products Sa filed Critical Philip Morris Products Sa
Publication of AP2015008563A0 publication Critical patent/AP2015008563A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/24Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241Extraction of specific substances
    • A24B15/245Nitrosamines
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B3/00Preparing tobacco in the factory
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacture Of Tobacco Products (AREA)
AP2015008563A 2012-12-21 2013-12-19 Tobacco specific nitrosamine reduction in plants AP2015008563A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12198966 2012-12-21
PCT/EP2013/077532 WO2014096283A2 (en) 2012-12-21 2013-12-19 Tobacco specific nitrosamine reduction in plants

Publications (1)

Publication Number Publication Date
AP2015008563A0 true AP2015008563A0 (en) 2015-06-30

Family

ID=47559184

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2015008563A AP2015008563A0 (en) 2012-12-21 2013-12-19 Tobacco specific nitrosamine reduction in plants

Country Status (11)

Country Link
US (1) US10563215B2 (enExample)
EP (1) EP2935588B1 (enExample)
JP (1) JP6693747B2 (enExample)
KR (1) KR102253223B1 (enExample)
CN (1) CN105247053B (enExample)
AP (1) AP2015008563A0 (enExample)
CA (1) CA2894955C (enExample)
MX (2) MX2015008084A (enExample)
PH (1) PH12015501204B1 (enExample)
RU (1) RU2735254C2 (enExample)
WO (1) WO2014096283A2 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9980509B2 (en) 2013-04-05 2018-05-29 R.J. Reynolds Tobacco Company Modification of bacterial profile of tobacco
CN107074919A (zh) * 2014-06-25 2017-08-18 菲利普莫里斯产品有限公司 通过氯化物通道的异位表达调节植物中的生物质
GB201501941D0 (en) 2015-02-05 2015-03-25 British American Tobacco Co Method
US20180291388A1 (en) * 2015-05-05 2018-10-11 North Carolina State University Methods and compositions for reducing the tobacco specific nitrosamine nnk in tobacco
EP3426786A1 (en) * 2016-03-11 2019-01-16 Altria Client Services LLC Compositions and methods for producing tobacco plants and products having reduced or eliminated suckers
EP3661354A1 (en) 2017-07-31 2020-06-10 R. J. Reynolds Tobacco Company Methods and compositions for viral-based gene editing in plants
CN111801423A (zh) 2018-03-28 2020-10-20 菲利普莫里斯生产公司 调节植物中的氨基酸含量
CN111818795A (zh) 2018-03-28 2020-10-23 菲利普莫里斯生产公司 调节植物中的还原糖含量
GB201812603D0 (en) 2018-08-02 2018-09-19 British American Tobacco Investments Ltd Method
JP2022515435A (ja) * 2018-12-30 2022-02-18 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 硝酸レダクターゼの突然変異による植物における硝酸塩レベルの調節
US12344853B2 (en) * 2019-06-05 2025-07-01 University Of Kentucky Research Foundation bZIP transcription factors regulate conversion of nicotine to nornicotine and reduce levels of tobacco specific (TSNA) precursors
CN110499388B (zh) * 2019-09-29 2023-03-24 云南省烟草农业科学研究院 鉴别烟草抗斑萎病位点rtsw等位基因类型的共显性标记引物组、鉴别方法及其应用
US12419264B2 (en) 2019-10-01 2025-09-23 Philip Morris Products S.A. Modulating sugar and amino acid content in a plant (SULTR3)
US12291714B2 (en) 2019-10-01 2025-05-06 Philip Morris Products S.A. Modulating reducing sugar content in a plant (INV)
CN111690661A (zh) * 2020-06-01 2020-09-22 云南省烟草农业科学研究院 一种烟草NtbHLH13基因突变体及分子鉴定方法和应用
WO2023036691A1 (en) 2021-09-10 2023-03-16 Philip Morris Products S.A. Modulating alkaloid profiles in nicotiana tabacum
WO2023117661A1 (en) 2021-12-20 2023-06-29 Philip Morris Products S.A. Increasing anatabine in tobacco leaf by regulating methyl putrescine oxidase
WO2023117701A1 (en) 2021-12-21 2023-06-29 Philip Morris Products S.A. Modulation of nicotine production by alteration of nicotinamidase expression or function in plants
JP7756726B2 (ja) * 2021-12-27 2025-10-20 日本たばこ産業株式会社 タバコ植物
EP4602060A1 (en) 2022-10-13 2025-08-20 Philip Morris Products S.A. Increasing leaf biomass and nitrogen use efficiency by regulating ntp2
CN120476136A (zh) 2023-02-02 2025-08-12 菲利普莫里斯生产公司 编码赖氨酸酮戊二酸还原酶的基因的调节
JP2026506774A (ja) 2023-02-02 2026-02-26 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 糖トランスポーターの調節
CN117025626B (zh) * 2023-06-29 2025-02-14 中国烟草总公司郑州烟草研究院 烟草硝酸盐转运蛋白NtNPF7.4及其编码基因、基因编辑载体和应用
CN117025627B (zh) * 2023-06-29 2024-11-01 中国烟草总公司郑州烟草研究院 烟草氯离子通道蛋白NtCLC13及其编码基因和应用
KR20260026072A (ko) 2023-06-29 2026-02-25 필립모리스 프로덕츠 에스.에이. 글루타메이트 탈수소효소 코딩 유전자의 조절
CN120944912B (zh) * 2025-09-17 2026-05-08 河南省农业科学院烟草研究所 NtGCN1基因及其在调控烟叶氯离子含量中的应用

Family Cites Families (19)

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US5810020A (en) 1993-09-07 1998-09-22 Osmotek, Inc. Process for removing nitrogen-containing anions and tobacco-specific nitrosamines from tobacco products
US6202649B1 (en) 1996-12-02 2001-03-20 Regent Court Technologies Method of treating tobacco to reduce nitrosamine content, and products produced thereby
US6586661B1 (en) * 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
AP1524A (en) 1997-06-20 2005-12-22 Regent Court Tech Method of treating tobacco to reduce nitrosamine content, and products produced thereby.
US7700834B2 (en) * 2001-11-13 2010-04-20 U.S. Smokless Tobacco Company Nicotiana nucleic acid molecules and uses thereof
RU2191529C1 (ru) 2001-12-21 2002-10-27 Романенко Александр Павлович Устройство для курения
PT1623634E (pt) * 2003-05-06 2013-08-23 Japan Tobacco Inc Processo de produção de material de tabaco regenerado
JP4160868B2 (ja) 2003-07-10 2008-10-08 日本たばこ産業株式会社 葉タバコ中のニトロソアミン含量の低減方法
CN1838878A (zh) * 2003-08-19 2006-09-27 二十二世纪有限公司 低危害的烟草产品
WO2006091194A1 (en) 2005-02-23 2006-08-31 North Carolina State University Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes
EP2087123B1 (en) 2006-10-13 2011-08-10 North Carolina State University Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes
RU2324737C1 (ru) * 2006-10-18 2008-05-20 Институт цитологии и генетики Сибирского отделения Российской академии наук (СО РАН) Способ получения трансгенных растений табака с повышенным содержанием пролина
DK2840142T3 (en) 2007-06-06 2019-03-18 Monsanto Technology Llc Genes and uses for plant improvement
US8124851B2 (en) 2007-11-12 2012-02-28 North Carolina State University Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes
CN104131030A (zh) 2007-12-13 2014-11-05 菲利普莫里斯生产公司 就减少的镉转运进行修饰的转基因植物、衍生产物和相关方法
WO2009091518A2 (en) 2008-01-15 2009-07-23 Monsanto Technology, Llc Isolated novel nucleic acid and protein molecules from corn and methods of using those molecules to generate transgenic plant with enhanced agronomic traits
DE112010003738T5 (de) * 2009-10-22 2013-08-14 Basf Plant Science Company Gmbh Pflanzen mit gesteigerten Ertragsmerkmalen und Verfahren zu deren Herstellung
CN102858983B (zh) 2010-01-15 2015-08-12 北卡罗来纳州立大学 最小化烟草中去甲烟碱合成的组合物和方法
TR201815375T4 (tr) 2010-09-03 2018-11-21 Philip Morris Products Sa Bitkilerde ağır metal redüksiyonu.

Also Published As

Publication number Publication date
US10563215B2 (en) 2020-02-18
JP2016508032A (ja) 2016-03-17
CA2894955C (en) 2023-10-31
EP2935588C0 (en) 2026-03-25
MX2019001598A (es) 2019-07-01
PH12015501204B1 (en) 2022-07-15
RU2015126909A (ru) 2017-01-27
WO2014096283A2 (en) 2014-06-26
CN105247053B (zh) 2020-07-31
MX2015008084A (es) 2016-03-31
CN105247053A (zh) 2016-01-13
EP2935588A2 (en) 2015-10-28
KR102253223B1 (ko) 2021-05-21
RU2735254C2 (ru) 2020-10-29
WO2014096283A3 (en) 2014-08-14
JP6693747B2 (ja) 2020-05-13
CA2894955A1 (en) 2014-06-26
EP2935588B1 (en) 2026-03-25
PH12015501204A1 (en) 2015-08-17
KR20150096451A (ko) 2015-08-24
US20150315603A1 (en) 2015-11-05

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