PE55097A1 - Isotiazolonas - Google Patents

Isotiazolonas

Info

Publication number
PE55097A1
PE55097A1 PE1996000385A PE00038596A PE55097A1 PE 55097 A1 PE55097 A1 PE 55097A1 PE 1996000385 A PE1996000385 A PE 1996000385A PE 00038596 A PE00038596 A PE 00038596A PE 55097 A1 PE55097 A1 PE 55097A1
Authority
PE
Peru
Prior art keywords
alkyl
cr6r7
phenyl
nr3r4
het
Prior art date
Application number
PE1996000385A
Other languages
English (en)
Inventor
Rocco Dean Gogliotti
Gary Louis Bolton
John Michael Domagala
Joseph Peter Sanchez
Bharat Kalidas Trivedi
Edward Faith Elslager
Terri Stoeber Purchase
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of PE55097A1 publication Critical patent/PE55097A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems

Abstract

SE REFIERE A COMPUESTOS DE FORMULA GENERAL (I), DONDE A ES UN ANILLO MONOCICLICO o BICICLICO, OPCIONALMENTE CON 1; 2 o 3 ATOMOS DE O, N Y S, SIENDO PREFERENTEMENTE UN MONOCICLO TAL COMO FENILO, PIRIDINA O PIRIMIDINA; R1 Y R2 SON INDEPENDIENTEMENTE H, -NR3R4 O HET(CR6R7)m, ENTRE OTROS; m ES 0; 1 o 2; R3, R4 Y R5 SON INDEPENDIENTEMENTE H, ALQUILO C1-C6, CICLOALQUILO, HET(CR6R7)m, O FENIL-(CR6R7)m-, DE LOS CUALES R5 ESTA OPCIONALMENTE SUSTITUIDO, SIENDO PREFERENTEMENTE: 2-IL-3-METIL PENTANOICO, 2-IL-4-METIL PENTANOICO O FENILO SUSTITUIDO POR S(O)2NR3R4, ADEMAS SIEMPRE QUE A ES FENILO SUSTITUIDO CON ALQUILO, HALOGENO, ALCOXI O NR3R4, ENTONCES R5 NO ES H, ALQUILO, CO-ALQUILO C1-C6 O FENIL-(CR6R7)m; R6 Y R7 SON H O ALQUILO C1-C6, ENTRE OTROS. SON USADOS COMO AGENTES ANTIRETROVIRUS POTENTES Y EN EL TRATAMIENTO DE INFLAMACIONES Y ATEROSCLEROSIS
PE1996000385A 1995-05-31 1996-05-30 Isotiazolonas PE55097A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/456,149 US5620997A (en) 1995-05-31 1995-05-31 Isothiazolones

Publications (1)

Publication Number Publication Date
PE55097A1 true PE55097A1 (es) 1998-01-16

Family

ID=23811632

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1996000385A PE55097A1 (es) 1995-05-31 1996-05-30 Isotiazolonas

Country Status (37)

Country Link
US (4) US5620997A (es)
EP (1) EP0828488B1 (es)
JP (1) JP2002502353A (es)
KR (2) KR20040004547A (es)
CN (1) CN1114402C (es)
AR (1) AR002740A1 (es)
AT (1) ATE232385T1 (es)
AU (1) AU723233B2 (es)
BG (1) BG62792B1 (es)
CA (1) CA2218253A1 (es)
CO (1) CO4700292A1 (es)
CZ (1) CZ373997A3 (es)
DE (1) DE69626203T2 (es)
DK (1) DK0828488T3 (es)
EA (1) EA000898B1 (es)
EE (1) EE9700287A (es)
ES (1) ES2192224T3 (es)
GE (1) GEP20012375B (es)
GT (1) GT199600026A (es)
HN (1) HN1996000017A (es)
HR (1) HRP960216B1 (es)
HU (1) HUP9900917A3 (es)
IL (1) IL117859A (es)
MX (1) MX9707948A (es)
MY (1) MY118452A (es)
NO (1) NO975496L (es)
NZ (1) NZ307023A (es)
OA (1) OA10745A (es)
PE (1) PE55097A1 (es)
PL (1) PL323683A1 (es)
PT (1) PT828488E (es)
SK (1) SK162297A3 (es)
SV (2) SV1996000026A (es)
TW (1) TW418206B (es)
UY (1) UY24244A1 (es)
WO (1) WO1996038144A1 (es)
ZA (1) ZA964441B (es)

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US5733921A (en) 1998-03-31
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