ES2031606T3 - Derivados de tiofeno - Google Patents
Derivados de tiofenoInfo
- Publication number
- ES2031606T3 ES2031606T3 ES198888310085T ES88310085T ES2031606T3 ES 2031606 T3 ES2031606 T3 ES 2031606T3 ES 198888310085 T ES198888310085 T ES 198888310085T ES 88310085 T ES88310085 T ES 88310085T ES 2031606 T3 ES2031606 T3 ES 2031606T3
- Authority
- ES
- Spain
- Prior art keywords
- rent
- group
- optionally protected
- alkylll
- aluminyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical class C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 1
- CIUQDSCDWFSTQR-UHFFFAOYSA-N [C]1=CC=CC=C1 Chemical class [C]1=CC=CC=C1 CIUQDSCDWFSTQR-UHFFFAOYSA-N 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 101100440695 Dictyostelium discoideum corB gene Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical class [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 239000002699 waste material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Electrophonic Musical Instruments (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Abstract
UN COMPUESTO DE LA FORMULA(I), EN LA QUE R1 ES C7 - 20 ALQUILO, C7 - 20 ALQUENILO O C7 - 20 ALQUINILO, SIENDO SUSTITUIDO OPCIONALMENTE EL GRUPO ALQUILO, ALQUENILO O ALQUINILO POR FENILO O FENILO SUSTITUIDO Y LOS GRUPOS ALQUENILO U ALQUINILO CON 1 A 3 ENLACES IBNSATURADOS; R2 ES (I) FENILO OPCIONALMENTE SUSTITUIDO, (II) C1 - 10 ALQUILO OPCIONALMENTE SUSTITUIDO POR UNO O MAS SUSTITUYENTES SELECCIONADOS DE HIDROXILO PROTEGIDO OPCIONALMENTE, CARBOXILO PROTEGIDO OPCIONALMENTE, NITRILO, TETRAZOILO PROTEGIDO OPCIONALMENTE, - COR4 O - NR5, Y - NHR6, SIENDO R6 H, UN GRUPO PROTECTOR, UN RESIDUO AMINOACIDO PROTEGIDO OPCIONALMENTE, C1 - 4 ALQUILO O - COR7, DONDE R7 ES C1 - 4 ALQUILO O C1 - 4 ALCOXI, O (III) C1 - 10 ALQUILO SUSTITUIDO CON UN GRUPO SELECCIONADO DE (II).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878725260A GB8725260D0 (en) | 1987-10-28 | 1987-10-28 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2031606T3 true ES2031606T3 (es) | 1992-12-16 |
Family
ID=10626046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES198888310085T Expired - Lifetime ES2031606T3 (es) | 1987-10-28 | 1988-10-27 | Derivados de tiofeno |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4886885A (es) |
| EP (1) | EP0314464B1 (es) |
| JP (1) | JPH01230572A (es) |
| AT (1) | ATE66919T1 (es) |
| DE (1) | DE3864660D1 (es) |
| ES (1) | ES2031606T3 (es) |
| GB (1) | GB8725260D0 (es) |
| GR (1) | GR3002958T3 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03204875A (ja) * | 1989-10-03 | 1991-09-06 | Wakamoto Pharmaceut Co Ltd | テトラゾール酢酸誘導体、及び該誘導体を有効成分とするアルドースレダクターゼ阻害剤 |
| JP2671059B2 (ja) * | 1990-11-30 | 1997-10-29 | 富士レビオ株式会社 | ナフトエ酸誘導体 |
| DE4124942A1 (de) * | 1991-07-27 | 1993-01-28 | Thomae Gmbh Dr K | 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US6162857A (en) | 1997-07-21 | 2000-12-19 | Eastman Chemical Company | Process for making polyester/platelet particle compositions displaying improved dispersion |
| US6734207B2 (en) * | 2001-04-20 | 2004-05-11 | Parker Hughes Institute | Cytotoxic compounds |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2424742C3 (de) * | 1974-05-21 | 1982-04-22 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Thiophenderivate Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| US4513005A (en) * | 1981-06-18 | 1985-04-23 | Lilly Industries Limited | SRS-A antagonists |
| EP0123543B1 (en) * | 1983-04-21 | 1988-02-03 | Merck Frosst Canada Inc. | Leukotriene antagonists, their production and use and compositions containing them |
| GB8320943D0 (en) * | 1983-08-03 | 1983-09-07 | Lilly Industries Ltd | Organic compounds |
| GB8432144D0 (en) * | 1984-12-20 | 1985-01-30 | Lilly Industries Ltd | Organic compounds |
| GB8502258D0 (en) * | 1985-01-30 | 1985-02-27 | Lilly Industries Ltd | Organic compounds |
| US4663332A (en) * | 1985-10-10 | 1987-05-05 | Hoffman-La Roche Inc. | 5-substituted N-alkylated tetrazoles |
| GB8530222D0 (en) * | 1985-12-07 | 1986-01-15 | Lilly Industries Ltd | Organic compounds |
| US4785004A (en) * | 1985-12-23 | 1988-11-15 | Ciba-Geigy Corporation | Aromatic thioethers |
| US4752613A (en) * | 1987-08-03 | 1988-06-21 | E. R. Squibb & Sons, Inc. | Sulphonamidothienylcarboxylic acid compounds |
-
1987
- 1987-10-28 GB GB878725260A patent/GB8725260D0/en active Pending
-
1988
- 1988-10-26 US US07/262,754 patent/US4886885A/en not_active Expired - Fee Related
- 1988-10-27 DE DE8888310085T patent/DE3864660D1/de not_active Expired - Fee Related
- 1988-10-27 JP JP63271911A patent/JPH01230572A/ja active Pending
- 1988-10-27 AT AT88310085T patent/ATE66919T1/de not_active IP Right Cessation
- 1988-10-27 ES ES198888310085T patent/ES2031606T3/es not_active Expired - Lifetime
- 1988-10-27 EP EP88310085A patent/EP0314464B1/en not_active Expired - Lifetime
-
1991
- 1991-10-22 GR GR91401589T patent/GR3002958T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH01230572A (ja) | 1989-09-14 |
| DE3864660D1 (en) | 1991-10-10 |
| GB8725260D0 (en) | 1987-12-02 |
| GR3002958T3 (en) | 1993-01-25 |
| EP0314464A1 (en) | 1989-05-03 |
| EP0314464B1 (en) | 1991-09-04 |
| ATE66919T1 (de) | 1991-09-15 |
| US4886885A (en) | 1989-12-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG2A | Definitive protection |
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