PE29898A1 - Procedimiento para el desdoblamiento de los racematos del tramadol - Google Patents

Procedimiento para el desdoblamiento de los racematos del tramadol

Info

Publication number
PE29898A1
PE29898A1 PE1996000930A PE00093096A PE29898A1 PE 29898 A1 PE29898 A1 PE 29898A1 PE 1996000930 A PE1996000930 A PE 1996000930A PE 00093096 A PE00093096 A PE 00093096A PE 29898 A1 PE29898 A1 PE 29898A1
Authority
PE
Peru
Prior art keywords
tramadol
procedure
racematos
del
unfolding
Prior art date
Application number
PE1996000930A
Other languages
English (en)
Spanish (es)
Inventor
Helmut Buschmann
Ivars Graudums
Werner Winter
Ursula Jansen
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of PE29898A1 publication Critical patent/PE29898A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PE1996000930A 1996-01-19 1996-12-18 Procedimiento para el desdoblamiento de los racematos del tramadol PE29898A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19601745A DE19601745C1 (de) 1996-01-19 1996-01-19 Verfahren zur Racematspaltung von Tramadol

Publications (1)

Publication Number Publication Date
PE29898A1 true PE29898A1 (es) 1998-08-08

Family

ID=7783112

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1996000930A PE29898A1 (es) 1996-01-19 1996-12-18 Procedimiento para el desdoblamiento de los racematos del tramadol

Country Status (31)

Country Link
US (1) US5723668A (OSRAM)
EP (1) EP0787715B1 (OSRAM)
JP (1) JPH09216858A (OSRAM)
KR (1) KR100505527B1 (OSRAM)
CN (1) CN1131203C (OSRAM)
AR (1) AR005391A1 (OSRAM)
AT (1) ATE189205T1 (OSRAM)
AU (1) AU711750B2 (OSRAM)
BR (1) BR9700094A (OSRAM)
CA (1) CA2195370C (OSRAM)
CO (1) CO4520185A1 (OSRAM)
CZ (1) CZ291775B6 (OSRAM)
DE (2) DE19601745C1 (OSRAM)
DK (1) DK0787715T3 (OSRAM)
ES (1) ES2145373T3 (OSRAM)
GR (1) GR3032489T3 (OSRAM)
HU (1) HU223067B1 (OSRAM)
IL (1) IL120028A (OSRAM)
IN (1) IN182218B (OSRAM)
MY (1) MY116583A (OSRAM)
NO (1) NO306059B1 (OSRAM)
NZ (1) NZ299999A (OSRAM)
PE (1) PE29898A1 (OSRAM)
PL (1) PL187403B1 (OSRAM)
PT (1) PT787715E (OSRAM)
RU (1) RU2192407C2 (OSRAM)
SI (1) SI0787715T1 (OSRAM)
SK (1) SK281612B6 (OSRAM)
UA (1) UA45343C2 (OSRAM)
UY (1) UY24439A1 (OSRAM)
ZA (1) ZA97369B (OSRAM)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2130079B1 (es) * 1997-07-10 2000-01-16 Esteve Labor Dr Resolucion de aminas
AU730530B2 (en) * 1997-07-15 2001-03-08 Russinsky Limited Tramadol, salts thereof and process for their preparation
DE19821039A1 (de) * 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
GB9826540D0 (en) 1998-12-02 1999-01-27 Darwin Discovery Ltd Process
KR100342919B1 (ko) * 1999-10-21 2002-07-04 박노중 트랜스체 염산 트라마돌의 분리 제조방법
IL155102A0 (en) * 2000-10-03 2003-10-31 Penwest Pharmaceuticals Co Delivery system for multi-pharmaceutical active materials at various release rates
DE10108122A1 (de) 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
JP4377585B2 (ja) 2001-03-16 2009-12-02 ディーエムアイ バイオサイエンシズ インコーポレイテッド 射精遅延の方法
US6649783B2 (en) * 2001-10-03 2003-11-18 Euro-Celtique, S.A. Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols
AU2002364517A1 (en) 2001-11-30 2003-06-17 Sepracor Inc. Tramadol analogs and uses thereof
US20040248979A1 (en) * 2003-06-03 2004-12-09 Dynogen Pharmaceuticals, Inc. Method of treating lower urinary tract disorders
CA2595519C (en) 2005-01-26 2013-10-29 Allergan, Inc. Methods of using as analgesics 1-benzyl-1-hydroxy-2,3-diamino-propyl amines, 3-benzyl-3-hydroxy-2-amino-propionic acid amides and related compounds
EP1785412A1 (en) 2005-11-14 2007-05-16 IPCA Laboratories Limited Tramadol recovery process
CA2677690C (en) * 2007-02-12 2012-05-15 James V. Winkler Treatment of comorbid premature ejaculation and erectile dysfunction
JP5550101B2 (ja) 2007-02-12 2014-07-16 ヴィリックス ファーマシューティカルズ インコーポレイテッド トラマドールの副作用の低減薬の製造におけるトラマドールおよびｐｄｅ阻害剤の使用方法
DE102013009114A1 (de) 2013-05-29 2014-12-04 Franz Gerstheimer Pharmazeutische Zusammensetzung zur Überwindung von Metabolisierungsproblemen
KR102136004B1 (ko) 2018-06-18 2020-07-22 (주)센텍코리아 감지부의 잔존 수명을 추정할 수 있는 음주측정기

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2528267A (en) * 1950-10-31 Eobeet j
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
IL50080A (en) * 1975-07-29 1979-07-25 Beecham Group Ltd 4-oxa-1-azabicyclo(3.2.0)heptan-7-one-2-car boxylic acid derivatives and their preparation
GB9017390D0 (en) * 1990-08-08 1990-09-19 Norgine Ltd Improvements in or relating to propylamine derivatives
JPH06122686A (ja) * 1992-10-12 1994-05-06 Fujisawa Pharmaceut Co Ltd ラセミ体の光学分割法

Also Published As

Publication number Publication date
CN1161957A (zh) 1997-10-15
ZA97369B (en) 1997-07-29
SK281612B6 (sk) 2001-05-10
UY24439A1 (es) 1997-01-30
NO970211L (no) 1997-07-21
SI0787715T1 (en) 2000-04-30
PT787715E (pt) 2000-06-30
EP0787715A1 (de) 1997-08-06
CZ291775B6 (cs) 2003-05-14
SK6897A3 (en) 1997-08-06
CO4520185A1 (es) 1997-10-15
CA2195370C (en) 2005-07-12
ATE189205T1 (de) 2000-02-15
MY116583A (en) 2004-02-28
KR100505527B1 (ko) 2005-10-19
AU711750B2 (en) 1999-10-21
DK0787715T3 (da) 2000-04-25
IL120028A0 (en) 1997-04-15
RU2192407C2 (ru) 2002-11-10
PL318003A1 (en) 1997-07-21
DE19601745C1 (de) 1997-10-09
US5723668A (en) 1998-03-03
DE59604295D1 (de) 2000-03-02
CZ15697A3 (cs) 1998-05-13
EP0787715B1 (de) 2000-01-26
CA2195370A1 (en) 1997-07-20
IN182218B (OSRAM) 1999-02-06
AR005391A1 (es) 1999-04-28
GR3032489T3 (en) 2000-05-31
HUP9700141A3 (en) 2000-03-28
PL187403B1 (pl) 2004-07-30
NO970211D0 (no) 1997-01-17
MX9700483A (es) 1997-07-31
AU1223297A (en) 1997-07-24
ES2145373T3 (es) 2000-07-01
NO306059B1 (no) 1999-09-13
IL120028A (en) 1999-12-22
UA45343C2 (uk) 2002-04-15
KR970059155A (ko) 1997-08-12
HU9700141D0 (en) 1997-03-28
HU223067B1 (hu) 2004-03-01
CN1131203C (zh) 2003-12-17
BR9700094A (pt) 1998-09-22
HUP9700141A2 (hu) 1998-01-28
NZ299999A (en) 1998-01-26
JPH09216858A (ja) 1997-08-19

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Legal Events

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FG Grant, registration
FD Application declared void or lapsed