PE21995A1 - Derivado de 2-carboxiindol - Google Patents
Derivado de 2-carboxiindolInfo
- Publication number
- PE21995A1 PE21995A1 PE1994252640A PE25264094A PE21995A1 PE 21995 A1 PE21995 A1 PE 21995A1 PE 1994252640 A PE1994252640 A PE 1994252640A PE 25264094 A PE25264094 A PE 25264094A PE 21995 A1 PE21995 A1 PE 21995A1
- Authority
- PE
- Peru
- Prior art keywords
- derivative
- adylene
- carboxyindol
- amino
- stricnin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939321221A GB9321221D0 (en) | 1993-10-14 | 1993-10-14 | Heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE21995A1 true PE21995A1 (es) | 1995-08-14 |
Family
ID=10743550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1994252640A PE21995A1 (es) | 1993-10-14 | 1994-10-12 | Derivado de 2-carboxiindol |
Country Status (27)
| Country | Link |
|---|---|
| US (3) | US5760059A (OSRAM) |
| EP (1) | EP0723541A1 (OSRAM) |
| JP (1) | JPH09503770A (OSRAM) |
| CN (1) | CN1070490C (OSRAM) |
| AP (1) | AP574A (OSRAM) |
| AU (1) | AU681194B2 (OSRAM) |
| BG (1) | BG61839B1 (OSRAM) |
| CA (1) | CA2171449A1 (OSRAM) |
| CO (1) | CO4290355A1 (OSRAM) |
| CZ (1) | CZ92396A3 (OSRAM) |
| FI (1) | FI961628A7 (OSRAM) |
| GB (1) | GB9321221D0 (OSRAM) |
| HU (1) | HU219710B (OSRAM) |
| IL (1) | IL111294A (OSRAM) |
| IS (1) | IS4219A (OSRAM) |
| MY (1) | MY112411A (OSRAM) |
| NO (1) | NO309861B1 (OSRAM) |
| NZ (1) | NZ274179A (OSRAM) |
| OA (1) | OA10578A (OSRAM) |
| PE (1) | PE21995A1 (OSRAM) |
| PL (1) | PL179568B1 (OSRAM) |
| RU (1) | RU2144535C1 (OSRAM) |
| SG (1) | SG49013A1 (OSRAM) |
| SK (1) | SK44996A3 (OSRAM) |
| TW (1) | TW283144B (OSRAM) |
| WO (1) | WO1995010517A1 (OSRAM) |
| ZA (1) | ZA947948B (OSRAM) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9321221D0 (en) * | 1993-10-14 | 1993-12-01 | Glaxo Spa | Heterocyclic compounds |
| GB9704498D0 (en) * | 1997-03-05 | 1997-04-23 | Glaxo Wellcome Spa | Chemical compound |
| GB9704499D0 (en) * | 1997-03-05 | 1997-04-23 | Glaxo Wellcome Spa | Method of manufacture |
| EP1163220A1 (en) * | 1999-03-23 | 2001-12-19 | Sumitomo Pharmaceuticals Company, Limited | Tricyclic indole-2-carboxylic acid compound used as nmda receptor antagonist |
| RU2209041C2 (ru) * | 2000-06-15 | 2003-07-27 | Новосибирский научно-исследовательский институт травматологии и ортопедии | Способ лечения церебрального вазоспазма |
| DE10153346A1 (de) | 2001-10-29 | 2004-04-22 | Grünenthal GmbH | Substituierte Indole |
| WO2003039540A2 (en) * | 2001-11-09 | 2003-05-15 | Sepracor Inc. | D-amino acid oxidase inhibitors for learning and memory |
| CZ2006427A3 (cs) | 2003-12-29 | 2006-11-15 | Sepracor Inc. | Pyrrolové a pyrazolové inhibitory DAAO |
| US20080293726A1 (en) | 2005-07-06 | 2008-11-27 | Sepracor Inc. | Combinations of Eszopiclone and Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-Napthalenamine or Trans 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-1-Napthalenamine, and Methods of Treatment of Menopause and Mood, Anxiety, and Cognitive Disorders |
| WO2007063010A1 (en) * | 2005-12-01 | 2007-06-07 | F. Hoffmann-La Roche Ag | Novel vinylogous acids derivatives |
| CN101426372A (zh) * | 2006-01-06 | 2009-05-06 | 塞普拉柯公司 | 基于四氢萘酮的单胺再摄取抑制剂 |
| BRPI0706365A2 (pt) * | 2006-01-06 | 2011-03-22 | Sepracor Inc | Cicloalquilaminas como inibidores da recaptação de monoamina |
| CN103588659A (zh) | 2006-03-31 | 2014-02-19 | 赛诺维信制药公司 | 手性酰胺和胺的制备 |
| US7579370B2 (en) * | 2006-06-30 | 2009-08-25 | Sepracor Inc. | Fused heterocycles |
| US7884124B2 (en) * | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| US20080082066A1 (en) * | 2006-10-02 | 2008-04-03 | Weyerhaeuser Co. | Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks |
| BRPI0806604A2 (pt) * | 2007-01-18 | 2011-09-06 | Sepracor Inc | inibidores de d-aminoácido oxidase |
| US7902252B2 (en) * | 2007-01-18 | 2011-03-08 | Sepracor, Inc. | Inhibitors of D-amino acid oxidase |
| BRPI0811639A2 (pt) | 2007-05-31 | 2014-09-30 | Sepracor Inc | Cicloaquilaminas fenil substituídas como inibidores da recaptação de monoamina |
| WO2010017418A1 (en) * | 2008-08-07 | 2010-02-11 | Sepracor Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
| WO2010104093A1 (ja) | 2009-03-10 | 2010-09-16 | 参天製薬株式会社 | ４，６－ジクロロ－１ｈ－インドール－２－カルボン酸誘導体又はその塩を有効成分として含有する視神経障害の予防又は治療剤 |
| US20110034434A1 (en) * | 2009-08-07 | 2011-02-10 | Sepracor Inc. | Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase |
| WO2013055386A2 (en) | 2011-10-03 | 2013-04-18 | The University Of Utah Research Foundation | Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome |
| IL248567B (en) | 2014-04-30 | 2022-08-01 | Univ Nat Taiwan | Use of known compounds as d-amino acid oxidase inhibitors |
| AU2017326359B2 (en) | 2016-09-14 | 2021-02-04 | National Chiao Tung University | Novel substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5256673A (en) * | 1983-11-25 | 1993-10-26 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Indole-3-yl-A-tetrahydropyridyl or piperidyl compounds |
| US4960786A (en) * | 1989-04-24 | 1990-10-02 | Merrell Dow Pharmaceuticals Inc. | Excitatory amino acid antagonists |
| JPH0347123A (ja) * | 1989-05-05 | 1991-02-28 | G D Searle & Co | インドール―２―カルボキシレート化合物類を含有するｃｎｓ疾患治療用組成物 |
| DE4101686A1 (de) * | 1991-01-22 | 1992-07-23 | Merck Patent Gmbh | Indolderivate |
| US5284862A (en) * | 1991-03-18 | 1994-02-08 | Warner-Lambert Company | Derivatives of 2-carboxyindoles having pharmaceutical activity |
| US5145845A (en) * | 1991-05-14 | 1992-09-08 | Warner-Lambert Co. | Substituted 2-carboxylindoles having pharmaceutical activity |
| EP0545478A1 (en) * | 1991-12-03 | 1993-06-09 | MERCK SHARP & DOHME LTD. | Heterocyclic compounds as tachykinin antagonists |
| GB9208492D0 (en) * | 1992-04-16 | 1992-06-03 | Glaxo Spa | Heterocyclic compounds |
| CZ181493A3 (en) * | 1992-09-10 | 1994-03-16 | Lilly Co Eli | The use of rhodanine derivative for the preparation of a pharmaceutical composition reducing level of sugar in blood and for treating alzheimer's disease |
| DE4333254A1 (de) * | 1993-09-30 | 1995-04-06 | Merck Patent Gmbh | Piperidine und Piperazine |
| GB9321221D0 (en) * | 1993-10-14 | 1993-12-01 | Glaxo Spa | Heterocyclic compounds |
-
1993
- 1993-10-14 GB GB939321221A patent/GB9321221D0/en active Pending
-
1994
- 1994-10-10 IS IS4219A patent/IS4219A/is unknown
- 1994-10-11 MY MYPI94002695A patent/MY112411A/en unknown
- 1994-10-12 ZA ZA947948A patent/ZA947948B/xx unknown
- 1994-10-12 SG SG1996005195A patent/SG49013A1/en unknown
- 1994-10-12 JP JP7511283A patent/JPH09503770A/ja active Pending
- 1994-10-12 CN CN94193759A patent/CN1070490C/zh not_active Expired - Fee Related
- 1994-10-12 WO PCT/EP1994/003359 patent/WO1995010517A1/en not_active Ceased
- 1994-10-12 NZ NZ274179A patent/NZ274179A/en unknown
- 1994-10-12 HU HU9600969A patent/HU219710B/hu not_active IP Right Cessation
- 1994-10-12 CO CO94046673A patent/CO4290355A1/es unknown
- 1994-10-12 CA CA002171449A patent/CA2171449A1/en not_active Abandoned
- 1994-10-12 SK SK449-96A patent/SK44996A3/sk unknown
- 1994-10-12 RU RU96108920A patent/RU2144535C1/ru active
- 1994-10-12 CZ CZ96923A patent/CZ92396A3/cs unknown
- 1994-10-12 AU AU78133/94A patent/AU681194B2/en not_active Ceased
- 1994-10-12 AP APAP/P/1994/000685A patent/AP574A/en active
- 1994-10-12 EP EP94928893A patent/EP0723541A1/en not_active Withdrawn
- 1994-10-12 US US08/619,510 patent/US5760059A/en not_active Expired - Fee Related
- 1994-10-12 PE PE1994252640A patent/PE21995A1/es not_active Application Discontinuation
- 1994-10-12 PL PL94313969A patent/PL179568B1/pl unknown
- 1994-10-13 IL IL11129494A patent/IL111294A/en not_active IP Right Cessation
- 1994-11-18 TW TW083110700A patent/TW283144B/zh active
-
1996
- 1996-04-09 OA OA60812A patent/OA10578A/en unknown
- 1996-04-12 FI FI961628A patent/FI961628A7/fi unknown
- 1996-04-12 NO NO961475A patent/NO309861B1/no not_active IP Right Cessation
- 1996-04-16 BG BG100511A patent/BG61839B1/bg unknown
-
1998
- 1998-05-29 US US09/086,522 patent/US5962496A/en not_active Expired - Lifetime
-
1999
- 1999-08-16 US US09/374,982 patent/US6100289A/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AE | Restoration of lapsed or forfeited application | ||
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |