IS4219A - Aðferð til framleiðslu á Indole afleiðum - Google Patents

Aðferð til framleiðslu á Indole afleiðum

Info

Publication number
IS4219A
IS4219A IS4219A IS4219A IS4219A IS 4219 A IS4219 A IS 4219A IS 4219 A IS4219 A IS 4219A IS 4219 A IS4219 A IS 4219A IS 4219 A IS4219 A IS 4219A
Authority
IS
Iceland
Prior art keywords
indole derivatives
producing indole
producing
derivatives
indole
Prior art date
Application number
IS4219A
Other languages
English (en)
Inventor
Cugola Alfredo
Di Fabio Romano
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Spa filed Critical Glaxo Spa
Publication of IS4219A publication Critical patent/IS4219A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
IS4219A 1993-10-14 1994-10-10 Aðferð til framleiðslu á Indole afleiðum IS4219A (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939321221A GB9321221D0 (en) 1993-10-14 1993-10-14 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
IS4219A true IS4219A (is) 1995-04-15

Family

ID=10743550

Family Applications (1)

Application Number Title Priority Date Filing Date
IS4219A IS4219A (is) 1993-10-14 1994-10-10 Aðferð til framleiðslu á Indole afleiðum

Country Status (27)

Country Link
US (3) US5760059A (is)
EP (1) EP0723541A1 (is)
JP (1) JPH09503770A (is)
CN (1) CN1070490C (is)
AP (1) AP574A (is)
AU (1) AU681194B2 (is)
BG (1) BG61839B1 (is)
CA (1) CA2171449A1 (is)
CO (1) CO4290355A1 (is)
CZ (1) CZ92396A3 (is)
FI (1) FI961628A0 (is)
GB (1) GB9321221D0 (is)
HU (1) HU219710B (is)
IL (1) IL111294A (is)
IS (1) IS4219A (is)
MY (1) MY112411A (is)
NO (1) NO309861B1 (is)
NZ (1) NZ274179A (is)
OA (1) OA10578A (is)
PE (1) PE21995A1 (is)
PL (1) PL179568B1 (is)
RU (1) RU2144535C1 (is)
SG (1) SG49013A1 (is)
SK (1) SK44996A3 (is)
TW (1) TW283144B (is)
WO (1) WO1995010517A1 (is)
ZA (1) ZA947948B (is)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9321221D0 (en) * 1993-10-14 1993-12-01 Glaxo Spa Heterocyclic compounds
GB9704498D0 (en) * 1997-03-05 1997-04-23 Glaxo Wellcome Spa Chemical compound
GB9704499D0 (en) 1997-03-05 1997-04-23 Glaxo Wellcome Spa Method of manufacture
CA2362700A1 (en) 1999-03-23 2000-09-28 Nobuyuki Ae Tricyclic indole-2-carboxylic acid compound used as nmda receptor antagonist
RU2209041C2 (ru) * 2000-06-15 2003-07-27 Новосибирский научно-исследовательский институт травматологии и ортопедии Способ лечения церебрального вазоспазма
DE10153346A1 (de) 2001-10-29 2004-04-22 Grünenthal GmbH Substituierte Indole
WO2003039540A2 (en) * 2001-11-09 2003-05-15 Sepracor Inc. D-amino acid oxidase inhibitors for learning and memory
RU2361862C2 (ru) 2003-12-29 2009-07-20 Сепракор Инк. Пиррольные и пиразольные ингибиторы daao
CA2614282A1 (en) 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
KR101026088B1 (ko) * 2005-12-01 2011-03-31 에프. 호프만-라 로슈 아게 신규한 비닐로구스산 유도체
US8053603B2 (en) * 2006-01-06 2011-11-08 Sunovion Pharmaceuticals Inc. Tetralone-based monoamine reuptake inhibitors
CA2636324C (en) 2006-01-06 2012-03-20 Sepracor Inc. Cycloalkylamines as monoamine reuptake inhibitors
CN101421228B (zh) 2006-03-31 2014-05-21 塞普拉柯公司 手性酰胺和胺的制备
US7884124B2 (en) * 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US7579370B2 (en) * 2006-06-30 2009-08-25 Sepracor Inc. Fused heterocycles
US20080082066A1 (en) * 2006-10-02 2008-04-03 Weyerhaeuser Co. Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks
KR20090111322A (ko) * 2007-01-18 2009-10-26 세프라코 아이엔시. 디 아미노산 옥시다제의 억제제
US7902252B2 (en) * 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
MX2009012685A (es) 2007-05-31 2009-12-14 Sepracor Inc Cicloalquilaminas sustituidas con fenilo como inhibidores de la reabsorcion de monoamina.
US20100120740A1 (en) * 2008-08-07 2010-05-13 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
WO2010104093A1 (ja) 2009-03-10 2010-09-16 参天製薬株式会社 4,6-ジクロロ-1h-インドール-2-カルボン酸誘導体又はその塩を有効成分として含有する視神経障害の予防又は治療剤
US20110034434A1 (en) * 2009-08-07 2011-02-10 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
EP3718547A1 (en) 2011-10-03 2020-10-07 The University of Utah Research Foundation Application of 5-ht6 receptor antagonists for the alleviation of cognitive deficits of down syndrome
WO2015168346A1 (en) 2014-04-30 2015-11-05 National Taiwan University Use of known compounds as d-amino acid oxidase inhibitors
NZ779170A (en) 2016-09-14 2025-08-29 Univ Nat Taiwan Novel substituted benzimidazole derivatives as d-amino acid oxidase (daao) inhibitors

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256673A (en) * 1983-11-25 1993-10-26 Merck Patent Gesellschaft Mit Beschrankter Haftung Indole-3-yl-A-tetrahydropyridyl or piperidyl compounds
US4960786A (en) * 1989-04-24 1990-10-02 Merrell Dow Pharmaceuticals Inc. Excitatory amino acid antagonists
PT93943A (pt) * 1989-05-05 1991-02-08 Searle & Co Processo para a preparacao de composicoes contendo compostos indole-2-carboxilato para tratamento de perturbacoes do snc
DE4101686A1 (de) * 1991-01-22 1992-07-23 Merck Patent Gmbh Indolderivate
US5284862A (en) * 1991-03-18 1994-02-08 Warner-Lambert Company Derivatives of 2-carboxyindoles having pharmaceutical activity
US5145845A (en) * 1991-05-14 1992-09-08 Warner-Lambert Co. Substituted 2-carboxylindoles having pharmaceutical activity
EP0545478A1 (en) * 1991-12-03 1993-06-09 MERCK SHARP & DOHME LTD. Heterocyclic compounds as tachykinin antagonists
GB9208492D0 (en) * 1992-04-16 1992-06-03 Glaxo Spa Heterocyclic compounds
IL106877A (en) * 1992-09-10 1998-03-10 Lilly Co Eli Rhodanine derivatives for use as medicaments for the treatment of alzheimer's disease
DE4333254A1 (de) * 1993-09-30 1995-04-06 Merck Patent Gmbh Piperidine und Piperazine
GB9321221D0 (en) * 1993-10-14 1993-12-01 Glaxo Spa Heterocyclic compounds

Also Published As

Publication number Publication date
CN1070490C (zh) 2001-09-05
US5962496A (en) 1999-10-05
BG61839B1 (bg) 1998-07-31
PL179568B1 (pl) 2000-09-29
CN1133042A (zh) 1996-10-09
ZA947948B (en) 1995-05-23
WO1995010517A1 (en) 1995-04-20
NO961475D0 (no) 1996-04-12
FI961628A7 (fi) 1996-04-12
HU9600969D0 (en) 1996-06-28
AU7813394A (en) 1995-05-04
CO4290355A1 (es) 1996-04-17
NO309861B1 (no) 2001-04-09
EP0723541A1 (en) 1996-07-31
AP574A (en) 1997-01-30
PE21995A1 (es) 1995-08-14
IL111294A0 (en) 1994-12-29
HU219710B (hu) 2001-06-28
HUT76065A (en) 1997-06-30
JPH09503770A (ja) 1997-04-15
CZ92396A3 (en) 1996-08-14
PL313969A1 (en) 1996-08-05
GB9321221D0 (en) 1993-12-01
OA10578A (en) 2002-06-07
US6100289A (en) 2000-08-08
NZ274179A (en) 1998-01-26
BG100511A (en) 1996-11-29
MY112411A (en) 2001-06-30
RU2144535C1 (ru) 2000-01-20
CA2171449A1 (en) 1995-04-20
US5760059A (en) 1998-06-02
SK44996A3 (en) 1997-01-08
AP9400685A0 (en) 1994-10-31
AU681194B2 (en) 1997-08-21
TW283144B (is) 1996-08-11
SG49013A1 (en) 1998-05-18
IL111294A (en) 1998-12-06
FI961628A0 (fi) 1996-04-12
NO961475L (no) 1996-04-12

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