PE20210121A1 - Regimenes de dosificacion superior de g1t38 - Google Patents
Regimenes de dosificacion superior de g1t38Info
- Publication number
- PE20210121A1 PE20210121A1 PE2020000908A PE2020000908A PE20210121A1 PE 20210121 A1 PE20210121 A1 PE 20210121A1 PE 2020000908 A PE2020000908 A PE 2020000908A PE 2020000908 A PE2020000908 A PE 2020000908A PE 20210121 A1 PE20210121 A1 PE 20210121A1
- Authority
- PE
- Peru
- Prior art keywords
- provides
- dosage regimen
- solid
- dose
- auc
- Prior art date
Links
- 239000007787 solid Substances 0.000 abstract 2
- -1 (5- (4-isopropylpiperazin-1-yl) pyridin-2-yl) amino Chemical group 0.000 abstract 1
- 229940124297 CDK 4/6 inhibitor Drugs 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000000440 neutrophil Anatomy 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862614952P | 2018-01-08 | 2018-01-08 | |
| US201862679575P | 2018-06-01 | 2018-06-01 | |
| US201962788017P | 2019-01-03 | 2019-01-03 | |
| PCT/US2019/012720 WO2019136451A1 (en) | 2018-01-08 | 2019-01-08 | G1t38 superior dosage regimes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20210121A1 true PE20210121A1 (es) | 2021-01-19 |
Family
ID=67143921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2020000908A PE20210121A1 (es) | 2018-01-08 | 2019-01-08 | Regimenes de dosificacion superior de g1t38 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US11357779B2 (https=) |
| EP (1) | EP3738084A4 (https=) |
| JP (1) | JP2021509680A (https=) |
| KR (1) | KR20200108867A (https=) |
| CN (1) | CN111837146B (https=) |
| AU (2) | AU2019205821C1 (https=) |
| BR (1) | BR112020013915A2 (https=) |
| CA (1) | CA3087570A1 (https=) |
| CO (1) | CO2020008825A2 (https=) |
| IL (1) | IL275708A (https=) |
| MX (2) | MX2020007312A (https=) |
| MY (1) | MY205589A (https=) |
| PE (1) | PE20210121A1 (https=) |
| PH (1) | PH12020551050A1 (https=) |
| RU (1) | RU2020123665A (https=) |
| SG (1) | SG11202005937QA (https=) |
| WO (1) | WO2019136451A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ME03557B (me) * | 2013-03-15 | 2020-07-20 | G1 Therapeutics Inc | Privremena zaštiтa normalnih ćelija током hemoterapije |
| KR20190092478A (ko) | 2016-12-05 | 2019-08-07 | 쥐원 쎄라퓨틱스, 인크. | 화학요법 레지멘 동안의 면역 반응의 보존 |
| MX2019008158A (es) | 2017-01-06 | 2019-12-09 | G1 Therapeutics Inc | Terapia de combinacion para el tratamiento del cancer. |
| EP3738084A4 (en) * | 2018-01-08 | 2021-11-17 | G1 Therapeutics, Inc. | SUPERIOR G1T38 DOSING SCHEMES |
| WO2019199883A1 (en) * | 2018-04-09 | 2019-10-17 | G1 Therapeutics, Inc. | Treatment of cancers having driving oncogenic mutations |
| TW202128174A (zh) * | 2019-10-09 | 2021-08-01 | 美商G1治療公司 | 失調之纖維母細胞生長因子受體訊息傳遞的癌症之標靶性治療 |
| KR20230012547A (ko) | 2020-05-19 | 2023-01-26 | 쥐원 쎄라퓨틱스, 인크. | 의학적 장애의 치료를 위한 시클린-의존성 키나제 억제 화합물 |
| US10988479B1 (en) | 2020-06-15 | 2021-04-27 | G1 Therapeutics, Inc. | Morphic forms of trilaciclib and methods of manufacture thereof |
| AU2021325426A1 (en) * | 2020-08-13 | 2023-03-09 | Astellas Pharma Inc. | Combination therapy |
| CA3210023A1 (en) * | 2021-01-29 | 2022-08-04 | Zhuhai United Laboratories Co., Ltd. | Oral preparation containing jak inhibitors or salts or crystal forms thereof, and preparation method and application thereof |
| US20220323446A1 (en) * | 2021-03-17 | 2022-10-13 | Amgen Inc. | Sotorasib dosing regimen |
| JP7564347B2 (ja) * | 2021-09-03 | 2024-10-08 | ノバルティス アーゲー | 多発性硬化症を治療するためのlou064 |
| WO2023243686A1 (ja) * | 2022-06-16 | 2023-12-21 | 日本たばこ産業株式会社 | ジヒドロオキサジアジノン化合物及びその医薬用途 |
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-
2019
- 2019-01-08 EP EP19736263.5A patent/EP3738084A4/en active Pending
- 2019-01-08 JP JP2020537622A patent/JP2021509680A/ja active Pending
- 2019-01-08 RU RU2020123665A patent/RU2020123665A/ru unknown
- 2019-01-08 BR BR112020013915-7A patent/BR112020013915A2/pt unknown
- 2019-01-08 MY MYPI2020003524A patent/MY205589A/en unknown
- 2019-01-08 SG SG11202005937QA patent/SG11202005937QA/en unknown
- 2019-01-08 CA CA3087570A patent/CA3087570A1/en active Pending
- 2019-01-08 PE PE2020000908A patent/PE20210121A1/es unknown
- 2019-01-08 MX MX2020007312A patent/MX2020007312A/es unknown
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- 2019-01-08 KR KR1020207022923A patent/KR20200108867A/ko not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| CN111837146A (zh) | 2020-10-27 |
| MX2024013788A (es) | 2024-12-06 |
| CA3087570A1 (en) | 2019-07-11 |
| JP2021509680A (ja) | 2021-04-01 |
| RU2020123665A (ru) | 2022-02-10 |
| WO2019136451A1 (en) | 2019-07-11 |
| US12364697B2 (en) | 2025-07-22 |
| AU2019205821B2 (en) | 2024-07-18 |
| EP3738084A4 (en) | 2021-11-17 |
| US20200405721A1 (en) | 2020-12-31 |
| AU2019205821C1 (en) | 2025-02-13 |
| US20260014160A1 (en) | 2026-01-15 |
| MY205589A (en) | 2024-10-28 |
| EP3738084A1 (en) | 2020-11-18 |
| IL275708A (en) | 2020-08-31 |
| AU2024205055A1 (en) | 2024-08-15 |
| KR20200108867A (ko) | 2020-09-21 |
| CO2020008825A2 (es) | 2020-07-31 |
| MX2020007312A (es) | 2021-01-08 |
| NZ765617A (en) | 2025-10-31 |
| SG11202005937QA (en) | 2020-07-29 |
| CN111837146B (zh) | 2024-10-15 |
| AU2019205821A1 (en) | 2020-07-09 |
| PH12020551050A1 (en) | 2021-08-23 |
| US11357779B2 (en) | 2022-06-14 |
| US20230149406A1 (en) | 2023-05-18 |
| BR112020013915A2 (pt) | 2020-12-01 |
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